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The map label for this gene is frzCD [H]

Identifier: 78223905

GI number: 78223905

Start: 3057852

End: 3059465

Strand: Direct

Name: frzCD [H]

Synonym: Gmet_2709

Alternate gene names: 78223905

Gene position: 3057852-3059465 (Clockwise)

Preceding gene: 78223904

Following gene: 78223906

Centisome position: 76.5

GC content: 62.7

Gene sequence:

>1614_bases
ATGGATATGCGAATACGGACACGGCTCCTTGTGAGTTTCGCGATCGTTCTGGCGCTCCTGGTGGGAGTCGGGGGCTATTC
CCTGAACCGGATGAACCTCCTGGCGGACCTCACCAACGATCTGTACGAACACCCCTTCACCGTCAGGAAGTCGATCCGCG
ATGCCTATCTCAACCTGATGCAGATGAACCGCTCCCTGAACAGGATGGTAACGTCGCCGGACAACACTATGGTCTCCGCG
GACATGCAGGCGATCAACGATTCCGAAAAGGAGTTCCTGAAGAACATGGGGATCATCAGGGAGCGGTTCCTCGGCAAGCA
GGGCGACGTTGACGACGTCATCAAGACCTATGAAGAGTGGAAGCCGCTCCGGGACCGGGTTATCGCCCTGACGGCCGCCA
ACCAGAAAGGGAAGGCGAAGGAACTCCTCTCCGGTGCCGAAGCGAAGCTTTTCACGGCCCTGGACAAGGAGACTGGAGAT
ATACTCAGCTTTTCCGACCGTAACGCAAGCGAGTTTTTCAAAGGGGCACAGAGTACGGCAAGGATGTCTCTGATCCTCAC
CGCCCTCGCCATTGCCGCCGCCGCCGGAATCGTCGTTCTGGTTGCCGTCACCCTCACCCGCAGCATCATCCGCCCCCTCG
GCACGGCAATGGGGGTCGCGGCGCGGGTGGCCGACGGCGACCTGACCGTGACGGTCCCCCCCGTCAGTGGGCAGGACGAG
ATGAACCTCCTCCTCCAGACCTTTGGCCGGATGGTGGAGAATCTCCGCCGGCAGGCCATGGATATCCAGGAGGGGGTGAA
CGTCCTTGCGGCCTCGGCGGGAGAGATCCTGGCCTCAACCACCCAGGTGGCCTCCAGCGCGGCCGAAACGGCGAGCGCCC
TGAACGAAACCACCGCCACCGTGGAAGAGGTGAAGCAGACCACGCAACTGGCCGCCCAGAAGGCCCGGAATGTGGCCGAC
ACCGCCCAGCGGTCGCTGCAGGTATCCCAGGGAGGGAGGAAAGCGGTGGAAAGCTCCGTCGAAGGGATGAACCGGATCCG
CGAGCAGATGGCGACCATCGCCGAGAGCATCGTGAACCTCAGCGAGCAGAGCCACGCCATCGGGGAGATTATCGCCACGG
TCAACGACCTGGCCGAGCAGTCGAACCTCCTGGCCGTCAACGCCTCCATCGAGGCGGCAAAGGCGGGGGAGCACGGCAAG
GGGTTTGCCGTGGTGGCCCATGAAGTCAAGAGCCTGGCCGACCAGTCGAAGCAGGCCACCGCCCAGGTGCGGGCGCTGCT
GAACGATATCCAGAAAGGGACCAACGCCGCGGTGATGGCGACGGAGCAGGGGAGCAAGGCTGTTGAGGCGGGCGAAAAAC
AGGCGGCTGAGGCGGGAGAGGCAATCCAGCTCCTGACGGAAAGCATCGCCGAATCGGCCAACGCCTCGGCCCAGATCACC
GCCACCAGCCAGCAGCAGTTGGTCGGCATGGATCAGGTGGCCCTGGCCATGGAAAACATCAGCGAGGCAAGCGCCCTGAG
CGTCACCAGCACGAAACAGGCCGAGTCCTCCGCCCAGAATCTCCATGAGTTGGGACAGAAGCTGAAGCGGCTGGTGGAGC
AACTCAAACTGTAA

Upstream 100 bases:

>100_bases
CCTCAACGACAGGCGCATCATCGTCAATGACGAAGGGTGAACGCCCATCGGGCAAAGTTTTCAATAACTACGCACTGAAG
AAAGGAAGAACGGGAACATG

Downstream 100 bases:

>100_bases
CGGGCAAGGGGCAATCTTGTATTCACCCGTGCGCCGACGCGCTTCAGCGCACAGGCACTGGTCGCCCCTACATGGAACAC
CCATGGATAAAGACTTTCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MDMRIRTRLLVSFAIVLALLVGVGGYSLNRMNLLADLTNDLYEHPFTVRKSIRDAYLNLMQMNRSLNRMVTSPDNTMVSA
DMQAINDSEKEFLKNMGIIRERFLGKQGDVDDVIKTYEEWKPLRDRVIALTAANQKGKAKELLSGAEAKLFTALDKETGD
ILSFSDRNASEFFKGAQSTARMSLILTALAIAAAAGIVVLVAVTLTRSIIRPLGTAMGVAARVADGDLTVTVPPVSGQDE
MNLLLQTFGRMVENLRRQAMDIQEGVNVLAASAGEILASTTQVASSAAETASALNETTATVEEVKQTTQLAAQKARNVAD
TAQRSLQVSQGGRKAVESSVEGMNRIREQMATIAESIVNLSEQSHAIGEIIATVNDLAEQSNLLAVNASIEAAKAGEHGK
GFAVVAHEVKSLADQSKQATAQVRALLNDIQKGTNAAVMATEQGSKAVEAGEKQAAEAGEAIQLLTESIAESANASAQIT
ATSQQQLVGMDQVALAMENISEASALSVTSTKQAESSAQNLHELGQKLKRLVEQLKL

Sequences:

>Translated_537_residues
MDMRIRTRLLVSFAIVLALLVGVGGYSLNRMNLLADLTNDLYEHPFTVRKSIRDAYLNLMQMNRSLNRMVTSPDNTMVSA
DMQAINDSEKEFLKNMGIIRERFLGKQGDVDDVIKTYEEWKPLRDRVIALTAANQKGKAKELLSGAEAKLFTALDKETGD
ILSFSDRNASEFFKGAQSTARMSLILTALAIAAAAGIVVLVAVTLTRSIIRPLGTAMGVAARVADGDLTVTVPPVSGQDE
MNLLLQTFGRMVENLRRQAMDIQEGVNVLAASAGEILASTTQVASSAAETASALNETTATVEEVKQTTQLAAQKARNVAD
TAQRSLQVSQGGRKAVESSVEGMNRIREQMATIAESIVNLSEQSHAIGEIIATVNDLAEQSNLLAVNASIEAAKAGEHGK
GFAVVAHEVKSLADQSKQATAQVRALLNDIQKGTNAAVMATEQGSKAVEAGEKQAAEAGEAIQLLTESIAESANASAQIT
ATSQQQLVGMDQVALAMENISEASALSVTSTKQAESSAQNLHELGQKLKRLVEQLKL
>Mature_537_residues
MDMRIRTRLLVSFAIVLALLVGVGGYSLNRMNLLADLTNDLYEHPFTVRKSIRDAYLNLMQMNRSLNRMVTSPDNTMVSA
DMQAINDSEKEFLKNMGIIRERFLGKQGDVDDVIKTYEEWKPLRDRVIALTAANQKGKAKELLSGAEAKLFTALDKETGD
ILSFSDRNASEFFKGAQSTARMSLILTALAIAAAAGIVVLVAVTLTRSIIRPLGTAMGVAARVADGDLTVTVPPVSGQDE
MNLLLQTFGRMVENLRRQAMDIQEGVNVLAASAGEILASTTQVASSAAETASALNETTATVEEVKQTTQLAAQKARNVAD
TAQRSLQVSQGGRKAVESSVEGMNRIREQMATIAESIVNLSEQSHAIGEIIATVNDLAEQSNLLAVNASIEAAKAGEHGK
GFAVVAHEVKSLADQSKQATAQVRALLNDIQKGTNAAVMATEQGSKAVEAGEKQAAEAGEAIQLLTESIAESANASAQIT
ATSQQQLVGMDQVALAMENISEASALSVTSTKQAESSAQNLHELGQKLKRLVEQLKL

Specific function: Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies. Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=293, Percent_Identity=32.4232081911263, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI2367378, Length=338, Percent_Identity=30.7692307692308, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787690, Length=396, Percent_Identity=26.7676767676768, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788194, Length=323, Percent_Identity=28.1733746130031, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=27.5229357798165, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57324; Mature: 57324

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMRIRTRLLVSFAIVLALLVGVGGYSLNRMNLLADLTNDLYEHPFTVRKSIRDAYLNLM
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QMNRSLNRMVTSPDNTMVSADMQAINDSEKEFLKNMGIIRERFLGKQGDVDDVIKTYEEW
HHHHHHHHHCCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KPLRDRVIALTAANQKGKAKELLSGAEAKLFTALDKETGDILSFSDRNASEFFKGAQSTA
HHHHHHEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
RMSLILTALAIAAAAGIVVLVAVTLTRSIIRPLGTAMGVAARVADGDLTVTVPPVSGQDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
MNLLLQTFGRMVENLRRQAMDIQEGVNVLAASAGEILASTTQVASSAAETASALNETTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEVKQTTQLAAQKARNVADTAQRSLQVSQGGRKAVESSVEGMNRIREQMATIAESIVNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEQSHAIGEIIATVNDLAEQSNLLAVNASIEAAKAGEHGKGFAVVAHEVKSLADQSKQAT
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQVRALLNDIQKGTNAAVMATEQGSKAVEAGEKQAAEAGEAIQLLTESIAESANASAQIT
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ATSQQQLVGMDQVALAMENISEASALSVTSTKQAESSAQNLHELGQKLKRLVEQLKL
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDMRIRTRLLVSFAIVLALLVGVGGYSLNRMNLLADLTNDLYEHPFTVRKSIRDAYLNLM
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QMNRSLNRMVTSPDNTMVSADMQAINDSEKEFLKNMGIIRERFLGKQGDVDDVIKTYEEW
HHHHHHHHHCCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KPLRDRVIALTAANQKGKAKELLSGAEAKLFTALDKETGDILSFSDRNASEFFKGAQSTA
HHHHHHEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
RMSLILTALAIAAAAGIVVLVAVTLTRSIIRPLGTAMGVAARVADGDLTVTVPPVSGQDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
MNLLLQTFGRMVENLRRQAMDIQEGVNVLAASAGEILASTTQVASSAAETASALNETTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEVKQTTQLAAQKARNVADTAQRSLQVSQGGRKAVESSVEGMNRIREQMATIAESIVNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEQSHAIGEIIATVNDLAEQSNLLAVNASIEAAKAGEHGKGFAVVAHEVKSLADQSKQAT
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
AQVRALLNDIQKGTNAAVMATEQGSKAVEAGEKQAAEAGEAIQLLTESIAESANASAQIT
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ATSQQQLVGMDQVALAMENISEASALSVTSTKQAESSAQNLHELGQKLKRLVEQLKL
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2492105; 1624419 [H]