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The map label for this gene is pepQ [H]

Identifier: 78223886

GI number: 78223886

Start: 3037032

End: 3038225

Strand: Reverse

Name: pepQ [H]

Synonym: Gmet_2690

Alternate gene names: 78223886

Gene position: 3038225-3037032 (Counterclockwise)

Preceding gene: 78223887

Following gene: 78223885

Centisome position: 76.0

GC content: 57.04

Gene sequence:

>1194_bases
ATGCGCCTTACCCCGAGGGATGAACTCGAATATCGCATCAAGAAGCTCCAGGCTTACATGGCGGAAGCGGGGCTCGATGC
CGTCATAGTTGTCCAGAATGCCGACCTCTTCTATTTCACCGGCACCATTCAGAACGGCGCTCTCTACGTGCCGGTGGCGG
GCGACCCCATCTACATGGTCCGCAAGGAGGTCTCCCGGGCTCGGATGGAATCCGGGCTGAAAGAGATTGTTCCCTTTGCC
TCCATGAGAGAAATCCCCGAGATTCTGACAAAGTACGGTTATGCTACGCCCATCCGCATCGGCATGGAATTCGATGTCGT
GCCGGTCAACTTCTTTGCCCGTTACCGCGCGGTCTTCCCTGCTGGCGATTTTGTCGATGCATCAACCCTTATCCGGCGTG
TCCGGATGATTAAAAGCAAATACGAGATTCACCTGCTCCAGGATGCGGCCAATCAGGTCGACAAGGTCTACCGCCGTGCC
CGGGAGGTTGTCCGCGAGGGGATGACCGATCTGGAACTGGCAGCAGAGCTTGAGTTCGCCGCCCGCAAGGAAGCGCACCA
GGGGTATGTCCGCATGAGGGGCTTCAATGCCGAACTCTTTTTTGCCCAGGTCTTCTCGGGAACCGATACCGCAGTTCCCG
CCTATATGGACACCCCTCTTGGGGGGCTCGGGCTCAATCCCTCCTTCGGGCAGGGGGCTGGGCTGAAGCGGATAGAGAGG
GGGGAGCCGATCATTGTCGACTTCGCCGGTTGCGTTGACGGCTACCTTGTGGACCAGACCCGCGTCATTGCTCTCGGCGC
TCTCTCCGATCGCATGAAAAAGGCCTATGATGACATGCTTCGGGTTCAGGAACGGATGACCGAAGTGGCCGTGCCCGGCA
CACCCTGGAGTCACGTTTACGATGTCTGTGTCGCCCTGGCCGCTGAACTCGGCTATGCCGACAATTTCATGGGGGCGAAG
GGGGCGCGGGTTTCCTTTATTGGTCATGGCATTGGTATAGAAGTCGACGAATACCCCTTTATCGCCAAGGGGTTTACGGA
CATGGTTCTCGAGCCGGGAATGGTTTTCGCGTTCGAACCGAAGGTCATCTTCCCCGGAGAGGGGGCCATCGGCATTGAGA
ACACTTTTTATATCTCCCATTATGAAGGGTTGAAGCAACTCACGTTCTCTGACCAGGAACTGCTTATTCTCTGA

Upstream 100 bases:

>100_bases
CGTCAGCTCCAGCGCAAGGCGCGGGCCGCCGCTTCAGAGCCGGAACAGCAGTAGATATAATCAGTGATTTTCTGACGATT
CAGTCCGGGAGAACCCAACC

Downstream 100 bases:

>100_bases
TTTTTCCCACCGCTGGCCGCTCTCTTTACCTGCTCCGTGGCTGTGTGTCCGCAGTCCACGGAGTCCTTGTCGCCTTCAGG
CGACGGTTGCTGTTTACGCA

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRLTPRDELEYRIKKLQAYMAEAGLDAVIVVQNADLFYFTGTIQNGALYVPVAGDPIYMVRKEVSRARMESGLKEIVPFA
SMREIPEILTKYGYATPIRIGMEFDVVPVNFFARYRAVFPAGDFVDASTLIRRVRMIKSKYEIHLLQDAANQVDKVYRRA
REVVREGMTDLELAAELEFAARKEAHQGYVRMRGFNAELFFAQVFSGTDTAVPAYMDTPLGGLGLNPSFGQGAGLKRIER
GEPIIVDFAGCVDGYLVDQTRVIALGALSDRMKKAYDDMLRVQERMTEVAVPGTPWSHVYDVCVALAAELGYADNFMGAK
GARVSFIGHGIGIEVDEYPFIAKGFTDMVLEPGMVFAFEPKVIFPGEGAIGIENTFYISHYEGLKQLTFSDQELLIL

Sequences:

>Translated_397_residues
MRLTPRDELEYRIKKLQAYMAEAGLDAVIVVQNADLFYFTGTIQNGALYVPVAGDPIYMVRKEVSRARMESGLKEIVPFA
SMREIPEILTKYGYATPIRIGMEFDVVPVNFFARYRAVFPAGDFVDASTLIRRVRMIKSKYEIHLLQDAANQVDKVYRRA
REVVREGMTDLELAAELEFAARKEAHQGYVRMRGFNAELFFAQVFSGTDTAVPAYMDTPLGGLGLNPSFGQGAGLKRIER
GEPIIVDFAGCVDGYLVDQTRVIALGALSDRMKKAYDDMLRVQERMTEVAVPGTPWSHVYDVCVALAAELGYADNFMGAK
GARVSFIGHGIGIEVDEYPFIAKGFTDMVLEPGMVFAFEPKVIFPGEGAIGIENTFYISHYEGLKQLTFSDQELLIL
>Mature_397_residues
MRLTPRDELEYRIKKLQAYMAEAGLDAVIVVQNADLFYFTGTIQNGALYVPVAGDPIYMVRKEVSRARMESGLKEIVPFA
SMREIPEILTKYGYATPIRIGMEFDVVPVNFFARYRAVFPAGDFVDASTLIRRVRMIKSKYEIHLLQDAANQVDKVYRRA
REVVREGMTDLELAAELEFAARKEAHQGYVRMRGFNAELFFAQVFSGTDTAVPAYMDTPLGGLGLNPSFGQGAGLKRIER
GEPIIVDFAGCVDGYLVDQTRVIALGALSDRMKKAYDDMLRVQERMTEVAVPGTPWSHVYDVCVALAAELGYADNFMGAK
GARVSFIGHGIGIEVDEYPFIAKGFTDMVLEPGMVFAFEPKVIFPGEGAIGIENTFYISHYEGLKQLTFSDQELLIL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=251, Percent_Identity=27.8884462151394, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44295; Mature: 44295

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPRDELEYRIKKLQAYMAEAGLDAVIVVQNADLFYFTGTIQNGALYVPVAGDPIYMV
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCHHHH
RKEVSRARMESGLKEIVPFASMREIPEILTKYGYATPIRIGMEFDVVPVNFFARYRAVFP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEHHHHHHHHEECC
AGDFVDASTLIRRVRMIKSKYEIHLLQDAANQVDKVYRRAREVVREGMTDLELAAELEFA
CCCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARKEAHQGYVRMRGFNAELFFAQVFSGTDTAVPAYMDTPLGGLGLNPSFGQGAGLKRIER
HHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHCC
GEPIIVDFAGCVDGYLVDQTRVIALGALSDRMKKAYDDMLRVQERMTEVAVPGTPWSHVY
CCCEEEEECCCCCCEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DVCVALAAELGYADNFMGAKGARVSFIGHGIGIEVDEYPFIAKGFTDMVLEPGMVFAFEP
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEECCCCCHHCCCHHHHCCCCEEEEECC
KVIFPGEGAIGIENTFYISHYEGLKQLTFSDQELLIL
EEEECCCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MRLTPRDELEYRIKKLQAYMAEAGLDAVIVVQNADLFYFTGTIQNGALYVPVAGDPIYMV
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCHHHH
RKEVSRARMESGLKEIVPFASMREIPEILTKYGYATPIRIGMEFDVVPVNFFARYRAVFP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEHHHHHHHHEECC
AGDFVDASTLIRRVRMIKSKYEIHLLQDAANQVDKVYRRAREVVREGMTDLELAAELEFA
CCCCCCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARKEAHQGYVRMRGFNAELFFAQVFSGTDTAVPAYMDTPLGGLGLNPSFGQGAGLKRIER
HHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHCC
GEPIIVDFAGCVDGYLVDQTRVIALGALSDRMKKAYDDMLRVQERMTEVAVPGTPWSHVY
CCCEEEEECCCCCCEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DVCVALAAELGYADNFMGAKGARVSFIGHGIGIEVDEYPFIAKGFTDMVLEPGMVFAFEP
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEECCCCCHHCCCHHHHCCCCEEEEECC
KVIFPGEGAIGIENTFYISHYEGLKQLTFSDQELLIL
EEEECCCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]