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The map label for this gene is atoC [H]

Identifier: 78223875

GI number: 78223875

Start: 3027590

End: 3027979

Strand: Reverse

Name: atoC [H]

Synonym: Gmet_2679

Alternate gene names: 78223875

Gene position: 3027979-3027590 (Counterclockwise)

Preceding gene: 78223876

Following gene: 78223874

Centisome position: 75.75

GC content: 48.97

Gene sequence:

>390_bases
TTGGCAGAGCAGGCAAAAAAACGGATACTGGTTGTTGACGACGAAGAGAATGCCCGGATAGGTCTGTCGAAACTTCTCGA
ACGGGAGGGATTCGAAGTCGAAAGCGTTTCGAATGGCTATGAAGCCCTTAACTATCTGAACCAGCGGCAGGTGAACGTTA
TTGTCACCGATATCAATATGCCGGAGATGAACGGCATCACCTTCCTCAAGGAACTCAACAAGAATTTCCCCGCGAGCAAC
GTCATCATGATTACTGCCTATGGCGGTGTTGAGTCGTATATCGAGGCCATGAACCTGGGGGCCTTTGAGTATATCAACAA
GCCCATCAAGATCGACGAGCTGAAGTCGATCCTGAAGAAGATTTTCAAGGAGAAGGAACACCGCCACTGA

Upstream 100 bases:

>100_bases
GGCCACGGGCAAAAAAGCGCTGCAACCGTCTGCTTGACAGGGGGGGACACCATGCTAGACTCAGATTCATCGTACCACGC
GCCAGAAGCGGAGTTTATCA

Downstream 100 bases:

>100_bases
TCTTGTCCACTCAAGCCAGATTCCTCCAGGGGGTAGAGCAATGAAAACCTTTTCCACCATTGTCTTTCCGACCGACTTTT
CCGAAAACTCGGAGTACGCC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MAEQAKKRILVVDDEENARIGLSKLLEREGFEVESVSNGYEALNYLNQRQVNVIVTDINMPEMNGITFLKELNKNFPASN
VIMITAYGGVESYIEAMNLGAFEYINKPIKIDELKSILKKIFKEKEHRH

Sequences:

>Translated_129_residues
MAEQAKKRILVVDDEENARIGLSKLLEREGFEVESVSNGYEALNYLNQRQVNVIVTDINMPEMNGITFLKELNKNFPASN
VIMITAYGGVESYIEAMNLGAFEYINKPIKIDELKSILKKIFKEKEHRH
>Mature_128_residues
AEQAKKRILVVDDEENARIGLSKLLEREGFEVESVSNGYEALNYLNQRQVNVIVTDINMPEMNGITFLKELNKNFPASNV
IMITAYGGVESYIEAMNLGAFEYINKPIKIDELKSILKKIFKEKEHRH

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=129, Percent_Identity=41.8604651162791, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=37.5, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=33.0357142857143, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1788905, Length=106, Percent_Identity=33.0188679245283, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=32.7731092436975, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=7e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=35.8333333333333, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=116, Percent_Identity=24.1379310344828, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 14792; Mature: 14661

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQAKKRILVVDDEENARIGLSKLLEREGFEVESVSNGYEALNYLNQRQVNVIVTDINM
CCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHCCCCEEEEEEECCC
PEMNGITFLKELNKNFPASNVIMITAYGGVESYIEAMNLGAFEYINKPIKIDELKSILKK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
IFKEKEHRH
HHHHHHCCC
>Mature Secondary Structure 
AEQAKKRILVVDDEENARIGLSKLLEREGFEVESVSNGYEALNYLNQRQVNVIVTDINM
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHCCCCEEEEEEECCC
PEMNGITFLKELNKNFPASNVIMITAYGGVESYIEAMNLGAFEYINKPIKIDELKSILKK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
IFKEKEHRH
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]