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The map label for this gene is atoS [H]

Identifier: 78223873

GI number: 78223873

Start: 3025823

End: 3027010

Strand: Reverse

Name: atoS [H]

Synonym: Gmet_2677

Alternate gene names: 78223873

Gene position: 3027010-3025823 (Counterclockwise)

Preceding gene: 78223874

Following gene: 78223872

Centisome position: 75.72

GC content: 58.33

Gene sequence:

>1188_bases
ATGACTACGGTAACTAACGCCTCTAAGGGTACCATTCTCATCATCGACGATGAGAAGGTAATCCTTGACCTCACCTCCAT
AGTCCTCAGTAACCGTGGTTACACGGTCTACACCGCTCCGGACGCCATGGTCGGCCTGGAAGAGTTGGAGGAGCATCATC
CAAGCCTGGTGCTCCTCGACTACATGATGCCGGTCATGGACGGTTTTACGGCCCTCAAGCAGATCCGGCAGAGATTCCCC
GATACCTATGTCATCATGTTCACCGGCAAGGGAAACGAGGAGATCGCCGTTGAACTCATGAAGGCCGGCGCCTCCGATTA
CATCCTCAAGCCCTTCAATAACCAGGATCTGGTGGAACGGATCGAGAGCGTCCTGCGGATCAGGGCGGTGGAGCTCAGGA
ACCGCGAGCTGATGGCGGAGCGGGATAAGCTTCTGGCCGAGATTGCAGAGTGGAACCGGGAGTTGGAGGAACGGGTGCGG
GAGAAGACCGAGGCTCTCCAGAAAGCCCAGGCGGAAATCGTCCAGTCGGAGAAGCTCGCTTCGCTGGGGTATCTTTCGGC
CGGCATGGCCCATGAGATCAGAAATCCCCTCAACTCCATCAATCTCTTTGCCCAGCTCCTGAAAAGCGGCTGCGAAGAAC
CGGAGAAGCTTGACTATATCGATAAGATCCTCAAGGAGGTGGACCGGATCGACGACATCATGCGCAAGCTCCTCGATGCG
TCCAAGCGCCCCCGCTTCCAGTTGAGCGAGGTGCGGCTCGACCGGGTCATCGATGCCACCCTGGAGGTGTTCAGACCCCA
GACCACCCTCTACGGCATCGAGGTGGTGAGGGCCTTCCGTCGTGTCCCTCCCCCCTTTCAGGCAGACCCCTCCGAGATCG
AGCAGATCTTCACCAACCTTTTCCTGAACGCCATCCACGAGATGCAGGAAGGCGGGACCCTTGCCGTCCTGCTCGACCAT
GACGACCGGGAGGTCATCATCCGGATCTCCGACACCGGCAGGGGAATGCCGCCGGATAATGTGAAGAAAATCTTTGATCC
CTTCTTCACCACCAAGACCAGCGGTAGCGGCCTCGGCCTTGCGGTGGTGCTCCGCATCGTCAAGACCTATCAGGGGAAGA
TCACCGTGGAGAAGAGCGACGAAACCGGCACCACCTTTGCCATCAGGCTCCCCCTTCTCCCTTCCTGA

Upstream 100 bases:

>100_bases
CCGAAGAGTAGTAATGTGGGCTCTGTTTCATGCAGGGCGGACAAAGGGCAGCTTTGGCTGCCCTTTGTTTTTATTCTGAC
AGGAAGAGATTTGCCACTCC

Downstream 100 bases:

>100_bases
CCCTGCCCCCTTTCTCCTTTTCTTTTCCACCCCGATTTTGTATGATGGCGCCCTGTTTTTCAGGGCTTTTGACGAATTAA
TACGATGCCGATTCTGATAC

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTTVTNASKGTILIIDDEKVILDLTSIVLSNRGYTVYTAPDAMVGLEELEEHHPSLVLLDYMMPVMDGFTALKQIRQRFP
DTYVIMFTGKGNEEIAVELMKAGASDYILKPFNNQDLVERIESVLRIRAVELRNRELMAERDKLLAEIAEWNRELEERVR
EKTEALQKAQAEIVQSEKLASLGYLSAGMAHEIRNPLNSINLFAQLLKSGCEEPEKLDYIDKILKEVDRIDDIMRKLLDA
SKRPRFQLSEVRLDRVIDATLEVFRPQTTLYGIEVVRAFRRVPPPFQADPSEIEQIFTNLFLNAIHEMQEGGTLAVLLDH
DDREVIIRISDTGRGMPPDNVKKIFDPFFTTKTSGSGLGLAVVLRIVKTYQGKITVEKSDETGTTFAIRLPLLPS

Sequences:

>Translated_395_residues
MTTVTNASKGTILIIDDEKVILDLTSIVLSNRGYTVYTAPDAMVGLEELEEHHPSLVLLDYMMPVMDGFTALKQIRQRFP
DTYVIMFTGKGNEEIAVELMKAGASDYILKPFNNQDLVERIESVLRIRAVELRNRELMAERDKLLAEIAEWNRELEERVR
EKTEALQKAQAEIVQSEKLASLGYLSAGMAHEIRNPLNSINLFAQLLKSGCEEPEKLDYIDKILKEVDRIDDIMRKLLDA
SKRPRFQLSEVRLDRVIDATLEVFRPQTTLYGIEVVRAFRRVPPPFQADPSEIEQIFTNLFLNAIHEMQEGGTLAVLLDH
DDREVIIRISDTGRGMPPDNVKKIFDPFFTTKTSGSGLGLAVVLRIVKTYQGKITVEKSDETGTTFAIRLPLLPS
>Mature_394_residues
TTVTNASKGTILIIDDEKVILDLTSIVLSNRGYTVYTAPDAMVGLEELEEHHPSLVLLDYMMPVMDGFTALKQIRQRFPD
TYVIMFTGKGNEEIAVELMKAGASDYILKPFNNQDLVERIESVLRIRAVELRNRELMAERDKLLAEIAEWNRELEERVRE
KTEALQKAQAEIVQSEKLASLGYLSAGMAHEIRNPLNSINLFAQLLKSGCEEPEKLDYIDKILKEVDRIDDIMRKLLDAS
KRPRFQLSEVRLDRVIDATLEVFRPQTTLYGIEVVRAFRRVPPPFQADPSEIEQIFTNLFLNAIHEMQEGGTLAVLLDHD
DREVIIRISDTGRGMPPDNVKKIFDPFFTTKTSGSGLGLAVVLRIVKTYQGKITVEKSDETGTTFAIRLPLLPS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=34.6320346320346, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=35.2422907488987, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081816, Length=262, Percent_Identity=28.6259541984733, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=28.2157676348548, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=29.6875, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=34.1269841269841, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=36.7521367521368, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=26.0089686098655, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=25.1101321585903, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788393, Length=215, Percent_Identity=25.1162790697674, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=34.1880341880342, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994928, Length=284, Percent_Identity=26.4084507042254, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789809, Length=123, Percent_Identity=36.5853658536585, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=21.9730941704036, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788394, Length=115, Percent_Identity=33.9130434782609, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=25.9109311740891, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790552, Length=115, Percent_Identity=32.1739130434783, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082012, Length=115, Percent_Identity=32.1739130434783, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44764; Mature: 44633

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50168 DED ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVTNASKGTILIIDDEKVILDLTSIVLSNRGYTVYTAPDAMVGLEELEEHHPSLVLLD
CCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEHH
YMMPVMDGFTALKQIRQRFPDTYVIMFTGKGNEEIAVELMKAGASDYILKPFNNQDLVER
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCHHHHHH
IESVLRIRAVELRNRELMAERDKLLAEIAEWNRELEERVREKTEALQKAQAEIVQSEKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGYLSAGMAHEIRNPLNSINLFAQLLKSGCEEPEKLDYIDKILKEVDRIDDIMRKLLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SKRPRFQLSEVRLDRVIDATLEVFRPQTTLYGIEVVRAFRRVPPPFQADPSEIEQIFTNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FLNAIHEMQEGGTLAVLLDHDDREVIIRISDTGRGMPPDNVKKIFDPFFTTKTSGSGLGL
HHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHH
AVVLRIVKTYQGKITVEKSDETGTTFAIRLPLLPS
HHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TTVTNASKGTILIIDDEKVILDLTSIVLSNRGYTVYTAPDAMVGLEELEEHHPSLVLLD
CCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEHH
YMMPVMDGFTALKQIRQRFPDTYVIMFTGKGNEEIAVELMKAGASDYILKPFNNQDLVER
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCHHHHHH
IESVLRIRAVELRNRELMAERDKLLAEIAEWNRELEERVREKTEALQKAQAEIVQSEKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGYLSAGMAHEIRNPLNSINLFAQLLKSGCEEPEKLDYIDKILKEVDRIDDIMRKLLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SKRPRFQLSEVRLDRVIDATLEVFRPQTTLYGIEVVRAFRRVPPPFQADPSEIEQIFTNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FLNAIHEMQEGGTLAVLLDHDDREVIIRISDTGRGMPPDNVKKIFDPFFTTKTSGSGLGL
HHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHH
AVVLRIVKTYQGKITVEKSDETGTTFAIRLPLLPS
HHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]