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The map label for this gene is ycbL [H]

Identifier: 78223870

GI number: 78223870

Start: 3022164

End: 3022793

Strand: Reverse

Name: ycbL [H]

Synonym: Gmet_2674

Alternate gene names: 78223870

Gene position: 3022793-3022164 (Counterclockwise)

Preceding gene: 78223871

Following gene: 78223869

Centisome position: 75.62

GC content: 64.44

Gene sequence:

>630_bases
ATGATCTTCGAAATCGTTGTTGTCGGCCCCATGGGGGTCAACTGCTTCATCCTCGGCTGTGAGGAAACCAAAGAGGGAGT
GGTGGTGGACCCCGGCGCCGATGCGGGGCGCATCCTCGACCGGGTCCGGGCTCTTGGCCTCACCATCCGCACGGTCATCA
ACACCCACGGCCACTTCGACCATATAGGGGGGAACAAGGCGGTCCTGGAGGCAACCGGCGGCCGGCTCATGATCCATCGG
GATGACGTCCACTTCCTGTCCCGGGCCGCGGACGTGGCGGCCAACTACGGCCTTTCCACCGCGAACTCCCCCCCGCCGGA
CGAGCTTCTTGAGGACGGGATGACGGTTACCTTCGGCAAATGCGCCATGAAGGTCTTCCACACGCCGGGTCACACGCCGG
GGGGATGCTGTCTCTACCTGGAAGGGGAGGGTAAGGTCATCACCGGGGACACCCTCTTTGCCGAGTCGGTGGGACGGACC
GATTTCCCCGGCTCCTCCCACGAGGCCCTTATAACCTCCATCCGCACGAAGCTCCTCCCCCTCCCCGACGAGACCCAGGT
CTTCCCGGGACACGGCGAGGCGAGCTCCATCGGGCGGGAGAAGCTGTACAATCCGTACCTGAACGGGTAG

Upstream 100 bases:

>100_bases
ATCAGTCCGATAGTTCCTGTTCGACAATTACCTGATTTTACTCCGTGCTCTCCGTTTCTCCGTGTTATTCGGACTGTATT
CTGTCTCGGGAGATACCGCT

Downstream 100 bases:

>100_bases
GAGACCATCCATGCTCAACGGCAAGCAGATCGTCCTCGGCGTCACCGGCGGCATAGCCGTCTACAAGGCGGTGGAGCTCG
TGCGGCTCCTGACCAAGGCG

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIFEIVVVGPMGVNCFILGCEETKEGVVVDPGADAGRILDRVRALGLTIRTVINTHGHFDHIGGNKAVLEATGGRLMIHR
DDVHFLSRAADVAANYGLSTANSPPPDELLEDGMTVTFGKCAMKVFHTPGHTPGGCCLYLEGEGKVITGDTLFAESVGRT
DFPGSSHEALITSIRTKLLPLPDETQVFPGHGEASSIGREKLYNPYLNG

Sequences:

>Translated_209_residues
MIFEIVVVGPMGVNCFILGCEETKEGVVVDPGADAGRILDRVRALGLTIRTVINTHGHFDHIGGNKAVLEATGGRLMIHR
DDVHFLSRAADVAANYGLSTANSPPPDELLEDGMTVTFGKCAMKVFHTPGHTPGGCCLYLEGEGKVITGDTLFAESVGRT
DFPGSSHEALITSIRTKLLPLPDETQVFPGHGEASSIGREKLYNPYLNG
>Mature_209_residues
MIFEIVVVGPMGVNCFILGCEETKEGVVVDPGADAGRILDRVRALGLTIRTVINTHGHFDHIGGNKAVLEATGGRLMIHR
DDVHFLSRAADVAANYGLSTANSPPPDELLEDGMTVTFGKCAMKVFHTPGHTPGGCCLYLEGEGKVITGDTLFAESVGRT
DFPGSSHEALITSIRTKLLPLPDETQVFPGHGEASSIGREKLYNPYLNG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=198, Percent_Identity=29.2929292929293, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI94538322, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI94538320, Length=181, Percent_Identity=28.1767955801105, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787158, Length=209, Percent_Identity=36.8421052631579, Blast_Score=154, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17538952, Length=212, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221330176, Length=212, Percent_Identity=28.7735849056604, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356335, Length=195, Percent_Identity=32.3076923076923, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24667711, Length=195, Percent_Identity=32.3076923076923, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24667703, Length=197, Percent_Identity=30.9644670050761, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 22272; Mature: 22272

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFEIVVVGPMGVNCFILGCEETKEGVVVDPGADAGRILDRVRALGLTIRTVINTHGHFD
CEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHEEHHHCCCCEE
HIGGNKAVLEATGGRLMIHRDDVHFLSRAADVAANYGLSTANSPPPDELLEDGMTVTFGK
ECCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEHH
CAMKVFHTPGHTPGGCCLYLEGEGKVITGDTLFAESVGRTDFPGSSHEALITSIRTKLLP
HEEEEEECCCCCCCCEEEEECCCCEEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
LPDETQVFPGHGEASSIGREKLYNPYLNG
CCCCCCEECCCCCHHHHCHHHHCCCCCCC
>Mature Secondary Structure
MIFEIVVVGPMGVNCFILGCEETKEGVVVDPGADAGRILDRVRALGLTIRTVINTHGHFD
CEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHEEHHHCCCCEE
HIGGNKAVLEATGGRLMIHRDDVHFLSRAADVAANYGLSTANSPPPDELLEDGMTVTFGK
ECCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEHH
CAMKVFHTPGHTPGGCCLYLEGEGKVITGDTLFAESVGRTDFPGSSHEALITSIRTKLLP
HEEEEEECCCCCCCCEEEEECCCCEEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
LPDETQVFPGHGEASSIGREKLYNPYLNG
CCCCCCEECCCCCHHHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]