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The map label for this gene is trxA [H]

Identifier: 78223850

GI number: 78223850

Start: 3001831

End: 3002943

Strand: Reverse

Name: trxA [H]

Synonym: Gmet_2654

Alternate gene names: 78223850

Gene position: 3002943-3001831 (Counterclockwise)

Preceding gene: 78223851

Following gene: 78223849

Centisome position: 75.12

GC content: 62.17

Gene sequence:

>1113_bases
ATGAAAAAAGCCATACGCCAACTCGTCATCACGTCACTGTTCGCCCTGCTGACCGTTTCGCCTCTCCTGGCCCAGGAGGA
AATTCCCGAGGCGGCTCGGGAGCGCTTCAAGGCCGGCTTCGCCATCATCGAAAAGGCGGACAGCCCTGCCGGTTTCCGTG
CCGCCATGGACGAGTTCGAGGCGGCCGCCGCCCTTGCTCCCCGCTGGCCCGACATCCACTACAACCTGGCAAAGGTGGCG
GCGGAAACGGACAAACCGGCCAAGGCCATCAATGAGTACCGTGCCTACCTGGCGCTGGCCCCCGAGGCGGCGGACCGGGC
CGCGGTGGAAGGGGATATTGCGCGGATGAAGGAGATGATCGCCCGGAAACGGAAGCTCGGCCTGCCCGGTGTCGTCTTTG
CCGCCATGCCGGACGGCATCTGGGTCATGGAGCTTGCTCCCGGGTCAAGGGTGGGGAAAACCCTCTTGAGGAAAGGGTAC
AAGATCCTTGCCGTCGAGGGTGAATCGGTTGTGGGAGCAAAGCTGGACGGGTTTTTCCGGGCCATTGAGACCCAGTCCGC
CAAGGTAGCCGCGGCCAAGAGCGAGGAAAAGAAACAGCCGGGGCAGATACCGGCCGGATTCAGGTCGGAGATGGGCTTCA
TCCGCTCCCAGAAGTTCATGCGGACGACCCAGCCAAACGCCGCCGGCAACGCGGTGGAGGAAACGGGGCCGGCCATCGCG
TTTACCGTCATCTCTCCCGGTTCCACTGACACCGGCAAGCTGTTCTTTAAGCAGAGCATGTTCCGCTCCAGCGTGATCGA
GATCGAAGAGGACGAGTTCGAGGATGAAGTCATCAAGGAGCGACTGCCAGTGGTGGTGACCTTCTGGGGGAGCGACTGCG
GCCCCTGCCAGGATTTCGTCCCGGCCGTGGAGGCGCAAAGCGCCAGGTATGCCGGCAAGGTCAAGTTCGTCAATGTCAAC
GTGAATGAGAACCGGAAGCTCGCCGGCCAGCTGGCTATCAAAGGGGTTCCGGCCATGATGGTCTACAAGGGGGGAAGTCC
CGTTTCCACCACGACCGGCAGGATCGACAATGCGAAGCTCGCGGAGCTTTTGCAGGGCGTAGCCGCCAATTAA

Upstream 100 bases:

>100_bases
CCGGAGTCAAGAAACTGGAACTTGAGATCGACGCCCTGAACGAAGTGGGCAAGCTGGCCACGGCGCCGAAAGCCGGCCAG
ACCACGAAAGGATCACAGCC

Downstream 100 bases:

>100_bases
GGGGAAAACCCGATGGGACGATTCTTTGTCAGTTCAGCCATGGTAGTTGTTTTGTTTGTCTCTGTTTCCGTCTCCCACGC
CCGGATGACCGACGCGGACC

Product: thioredoxin-related protein

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKKAIRQLVITSLFALLTVSPLLAQEEIPEAARERFKAGFAIIEKADSPAGFRAAMDEFEAAAALAPRWPDIHYNLAKVA
AETDKPAKAINEYRAYLALAPEAADRAAVEGDIARMKEMIARKRKLGLPGVVFAAMPDGIWVMELAPGSRVGKTLLRKGY
KILAVEGESVVGAKLDGFFRAIETQSAKVAAAKSEEKKQPGQIPAGFRSEMGFIRSQKFMRTTQPNAAGNAVEETGPAIA
FTVISPGSTDTGKLFFKQSMFRSSVIEIEEDEFEDEVIKERLPVVVTFWGSDCGPCQDFVPAVEAQSARYAGKVKFVNVN
VNENRKLAGQLAIKGVPAMMVYKGGSPVSTTTGRIDNAKLAELLQGVAAN

Sequences:

>Translated_370_residues
MKKAIRQLVITSLFALLTVSPLLAQEEIPEAARERFKAGFAIIEKADSPAGFRAAMDEFEAAAALAPRWPDIHYNLAKVA
AETDKPAKAINEYRAYLALAPEAADRAAVEGDIARMKEMIARKRKLGLPGVVFAAMPDGIWVMELAPGSRVGKTLLRKGY
KILAVEGESVVGAKLDGFFRAIETQSAKVAAAKSEEKKQPGQIPAGFRSEMGFIRSQKFMRTTQPNAAGNAVEETGPAIA
FTVISPGSTDTGKLFFKQSMFRSSVIEIEEDEFEDEVIKERLPVVVTFWGSDCGPCQDFVPAVEAQSARYAGKVKFVNVN
VNENRKLAGQLAIKGVPAMMVYKGGSPVSTTTGRIDNAKLAELLQGVAAN
>Mature_370_residues
MKKAIRQLVITSLFALLTVSPLLAQEEIPEAARERFKAGFAIIEKADSPAGFRAAMDEFEAAAALAPRWPDIHYNLAKVA
AETDKPAKAINEYRAYLALAPEAADRAAVEGDIARMKEMIARKRKLGLPGVVFAAMPDGIWVMELAPGSRVGKTLLRKGY
KILAVEGESVVGAKLDGFFRAIETQSAKVAAAKSEEKKQPGQIPAGFRSEMGFIRSQKFMRTTQPNAAGNAVEETGPAIA
FTVISPGSTDTGKLFFKQSMFRSSVIEIEEDEFEDEVIKERLPVVVTFWGSDCGPCQDFVPAVEAQSARYAGKVKFVNVN
VNENRKLAGQLAIKGVPAMMVYKGGSPVSTTTGRIDNAKLAELLQGVAAN

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=91, Percent_Identity=36.2637362637363, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082331, Length=100, Percent_Identity=29, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI212646193, Length=108, Percent_Identity=31.4814814814815, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 39942; Mature: 39942

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAIRQLVITSLFALLTVSPLLAQEEIPEAARERFKAGFAIIEKADSPAGFRAAMDEFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHEEECCCCCCHHHHHHHHHH
AAAALAPRWPDIHYNLAKVAAETDKPAKAINEYRAYLALAPEAADRAAVEGDIARMKEMI
HHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
ARKRKLGLPGVVFAAMPDGIWVMELAPGSRVGKTLLRKGYKILAVEGESVVGAKLDGFFR
HHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCEEEEECCCCEECHHHHHHHH
AIETQSAKVAAAKSEEKKQPGQIPAGFRSEMGFIRSQKFMRTTQPNAAGNAVEETGPAIA
HHHCCCCCEEHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEE
FTVISPGSTDTGKLFFKQSMFRSSVIEIEEDEFEDEVIKERLPVVVTFWGSDCGPCQDFV
EEEECCCCCCCHHHHHHHHHHHHHCEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
PAVEAQSARYAGKVKFVNVNVNENRKLAGQLAIKGVPAMMVYKGGSPVSTTTGRIDNAKL
HHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
AELLQGVAAN
HHHHHHHCCC
>Mature Secondary Structure
MKKAIRQLVITSLFALLTVSPLLAQEEIPEAARERFKAGFAIIEKADSPAGFRAAMDEFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHEEECCCCCCHHHHHHHHHH
AAAALAPRWPDIHYNLAKVAAETDKPAKAINEYRAYLALAPEAADRAAVEGDIARMKEMI
HHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
ARKRKLGLPGVVFAAMPDGIWVMELAPGSRVGKTLLRKGYKILAVEGESVVGAKLDGFFR
HHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCEEEEECCCCEECHHHHHHHH
AIETQSAKVAAAKSEEKKQPGQIPAGFRSEMGFIRSQKFMRTTQPNAAGNAVEETGPAIA
HHHCCCCCEEHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEE
FTVISPGSTDTGKLFFKQSMFRSSVIEIEEDEFEDEVIKERLPVVVTFWGSDCGPCQDFV
EEEECCCCCCCHHHHHHHHHHHHHCEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
PAVEAQSARYAGKVKFVNVNVNENRKLAGQLAIKGVPAMMVYKGGSPVSTTTGRIDNAKL
HHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHH
AELLQGVAAN
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2137818; 3280308 [H]