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The map label for this gene is 78223791

Identifier: 78223791

GI number: 78223791

Start: 2944016

End: 2944978

Strand: Direct

Name: 78223791

Synonym: Gmet_2594

Alternate gene names: NA

Gene position: 2944016-2944978 (Clockwise)

Preceding gene: 78223787

Following gene: 78223792

Centisome position: 73.65

GC content: 63.45

Gene sequence:

>963_bases
ATGAAATCGACGCGTATTAACAGATGGGGAATCTTGGGGCTGTTGCTGGCTCTCGTGCTGCAGGCACCGGGCCTGGCCAC
GGCGCAAACCACGTTCGGGCGGATCGTGGTGTTCGGCGACAGCCTGTCCGATCCCGGCAACCTGTTTGCCCTGGAGGGGG
GAGCGAACACTCCACCCTACAACACCCTGGACCAGCTCCTCATTCCTGACAAGCCCTATGCGAGGGGGGGACACCATTTC
AGTAACGGTGCAACCTGGATTGAGCAGCTTTCGCGGCCGTTGGGGCTCGCCGGGAACACCCGTCCCGCCTTTCTGGGATC
GGATACCGAGGCCACCAATTACGCAGTAGGTGGCGCCAGGGCCCATGACGACGGGATCAACGTCAACCTCCAGGCCCAGG
TGACTGCGTTCCTCAACACTGTCGGCGGCGCTGCCCCGGCCGATGCCCTCTACGTGGTGGAGTTCGGCAGCAACGACATC
CGCGACGCCCTGGCGGCGGGCGCTGCCGGTGGACCCATCCTTGAAGGCGCCCTTGCCTCCGTCGGCAACAACCTCGGGGC
ACTCTACGCGGCAGGTGCGCGGAAGTTCCTGGTATGCAACGCGCCCGACATCTCGCTGACCCCCGCCGTTCTCACCCTTG
ACAAGCTCTCCCCCGGCGCAGGCCAATTCGCCAGCTTTCTGACGATGACCTACAACTCGGGGCTCAACCTTCTTCTGGGG
TCGTTGGCAGGGCTTCCCGGCATCGAGATTGTGCGGGTTGATTTCTTCCAGAAACTGCACGAGCTGGTTGCCACTCCCGC
TGCATTCGGTCTGAGCGTGGTGGACAGGGCCTGTGTAATGCCCGACACCCCGCCGTTCGCCTGCCAGTACCCTGATCAGT
TCCTGTTCTGGGATGGGACCCACCCGACCCAGGCGGTCCATGCCATCATGTCGCAAGAGGCGACATCCGCGCTGGCAAAC
TGA

Upstream 100 bases:

>100_bases
TTCGATTGTCAGAGAACTTTGTCTACGATGTGCTGGCACATTTTTCTGTCCACGATGTCGTGGCACTCAACAAGTAACCA
ACAACCAGGGAGGGCAAAAC

Downstream 100 bases:

>100_bases
TCGTCCCGGAACAGACGCAAGAGAACCAATCACACAAAAAAGGGCGCCGCACACCATGCGACGCCCCTTTTCAGATGCAA
TTCTGCCTATGCAGCGAGGG

Product: lipolytic protein

Products: NA

Alternate protein names: Glycerophospholipid-cholesterol acyltransferase; GCAT [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKSTRINRWGILGLLLALVLQAPGLATAQTTFGRIVVFGDSLSDPGNLFALEGGANTPPYNTLDQLLIPDKPYARGGHHF
SNGATWIEQLSRPLGLAGNTRPAFLGSDTEATNYAVGGARAHDDGINVNLQAQVTAFLNTVGGAAPADALYVVEFGSNDI
RDALAAGAAGGPILEGALASVGNNLGALYAAGARKFLVCNAPDISLTPAVLTLDKLSPGAGQFASFLTMTYNSGLNLLLG
SLAGLPGIEIVRVDFFQKLHELVATPAAFGLSVVDRACVMPDTPPFACQYPDQFLFWDGTHPTQAVHAIMSQEATSALAN

Sequences:

>Translated_320_residues
MKSTRINRWGILGLLLALVLQAPGLATAQTTFGRIVVFGDSLSDPGNLFALEGGANTPPYNTLDQLLIPDKPYARGGHHF
SNGATWIEQLSRPLGLAGNTRPAFLGSDTEATNYAVGGARAHDDGINVNLQAQVTAFLNTVGGAAPADALYVVEFGSNDI
RDALAAGAAGGPILEGALASVGNNLGALYAAGARKFLVCNAPDISLTPAVLTLDKLSPGAGQFASFLTMTYNSGLNLLLG
SLAGLPGIEIVRVDFFQKLHELVATPAAFGLSVVDRACVMPDTPPFACQYPDQFLFWDGTHPTQAVHAIMSQEATSALAN
>Mature_320_residues
MKSTRINRWGILGLLLALVLQAPGLATAQTTFGRIVVFGDSLSDPGNLFALEGGANTPPYNTLDQLLIPDKPYARGGHHF
SNGATWIEQLSRPLGLAGNTRPAFLGSDTEATNYAVGGARAHDDGINVNLQAQVTAFLNTVGGAAPADALYVVEFGSNDI
RDALAAGAAGGPILEGALASVGNNLGALYAAGARKFLVCNAPDISLTPAVLTLDKLSPGAGQFASFLTMTYNSGLNLLLG
SLAGLPGIEIVRVDFFQKLHELVATPAAFGLSVVDRACVMPDTPPFACQYPDQFLFWDGTHPTQAVHAIMSQEATSALAN

Specific function: Fatty acid transfer between phosphatidylcholine and cholesterol [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =2.3.1.43 [H]

Molecular weight: Translated: 33276; Mature: 33276

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTRINRWGILGLLLALVLQAPGLATAQTTFGRIVVFGDSLSDPGNLFALEGGANTPPY
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCC
NTLDQLLIPDKPYARGGHHFSNGATWIEQLSRPLGLAGNTRPAFLGSDTEATNYAVGGAR
CCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEECCCCC
AHDDGINVNLQAQVTAFLNTVGGAAPADALYVVEFGSNDIRDALAAGAAGGPILEGALAS
CCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHHHHHH
VGNNLGALYAAGARKFLVCNAPDISLTPAVLTLDKLSPGAGQFASFLTMTYNSGLNLLLG
HCCCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHH
SLAGLPGIEIVRVDFFQKLHELVATPAAFGLSVVDRACVMPDTPPFACQYPDQFLFWDGT
HHCCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCC
HPTQAVHAIMSQEATSALAN
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSTRINRWGILGLLLALVLQAPGLATAQTTFGRIVVFGDSLSDPGNLFALEGGANTPPY
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCC
NTLDQLLIPDKPYARGGHHFSNGATWIEQLSRPLGLAGNTRPAFLGSDTEATNYAVGGAR
CCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEECCCCC
AHDDGINVNLQAQVTAFLNTVGGAAPADALYVVEFGSNDIRDALAAGAAGGPILEGALAS
CCCCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCHHHHHHHHH
VGNNLGALYAAGARKFLVCNAPDISLTPAVLTLDKLSPGAGQFASFLTMTYNSGLNLLLG
HCCCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHH
SLAGLPGIEIVRVDFFQKLHELVATPAAFGLSVVDRACVMPDTPPFACQYPDQFLFWDGT
HHCCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCC
HPTQAVHAIMSQEATSALAN
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2271578; 3280033; 1985976; 8294469 [H]