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The map label for this gene is namA [H]

Identifier: 78223774

GI number: 78223774

Start: 2924810

End: 2925877

Strand: Reverse

Name: namA [H]

Synonym: Gmet_2577

Alternate gene names: 78223774

Gene position: 2925877-2924810 (Counterclockwise)

Preceding gene: 78223775

Following gene: 78223772

Centisome position: 73.19

GC content: 68.45

Gene sequence:

>1068_bases
ATGAGTGCCCTTTTCACTCCCTTTACCCTGCGGTCGGTCACCTTCCGCAACCGCATCTTCGTCTCCCCCATGTGCCAGTA
TTCGAGCCTTGACGGGATGCCTACCGACTGGCATCTGGTCCACTTGGGGAGCCGGGCCGTGGGGGGAGCGGGTCTCGTGA
TGGTGGAGGCGACGGCGGTGAGTCCCGAGGGGCGCATCAGCCCCGACGACAGCGGCATCTGGGACGACCGGCATGGGGAG
GGGTTCGCCCCTATCACCCGCTTCATCGCCGAGCAGGGGGCGGTTCCCGGAATCCAACTGGCCCATGCGGGCCGCAAGGC
CTCCACCGATCTCCCCTGGCGCGGCGGGCTCCCCTTGGGGCCAGAGGCCCGGGGGTGGCAGCCGGTGGCGCCGAGCCCCC
GCCCCTTCGCGGCCGATTATCCCGTTCCCCGGGAGCTGACGGTGGAGGAGATGGACGATGTGGTCAGCCAGTTCCGGGAT
GGGGCCCAACGGGCGTTGGCCGCCGGTTTCCAGGTGGTGGAAATTCACATGGCCCACGGCTATCTTCTCCACGAGTTCCT
CTCCCCCCTCTCGAACCGACGGACGGACGACTTCGGCGGCAGCCTGGAGAACCGGATCCGTCTCCCCCTTCGGGTGACCC
GGGCGGTGCGGGAGGTGTGGCCCGCCGATCTCCCCCTCTTTGTCCGGATATCCGCCACCGACTGGGTCGAGGGTGGATGG
GACCTGGATCAATCGGTGGTCCTTGCCCGAAAGCTGAGGGAGGCTGGCGTCGACCTCGTCGACTGCTCGGCCGGCTTCCT
CACTCCCGACGCGGTCATCCCCTTCGGATCGGGGTACCAGACCCCCTTTGCCACTGCCATCCGGCGCGAGGCCGGAATCC
CCACGGGGACCGTCGGTTTCATTACCGACCCGGCCCAGGCGGAGCAGATCGTGGCCACGGGGCTCGCCGACGCGGTACTC
CTGGCCCGGGAGATGCTCAGGGATCCCTACTGGCCCCTCCACGCCGCCCGTTCCCTCGGGGTCAACGTTCCGTGGCCTCC
CCAGTATGAGCGGGCGAAACTCCCCTGA

Upstream 100 bases:

>100_bases
ACCGTCGCCGTCGCTAGCCGTCTGTCCCGTCTTCCATTCCTTTACTCCCCCCTTCCGTCTGATACACTCTTCCTGAACAC
CACGAACGGAGGAGATCCCC

Downstream 100 bases:

>100_bases
TAGCCGCAATTACATGGTATAAAGCGTATCGTCGTGGGCCGGGGGGGCGAGCCTCTTTTTTATCCCCCGAATCCCCTCTT
TGGCAAAGGGATTGTCGGCG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSALFTPFTLRSVTFRNRIFVSPMCQYSSLDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSPEGRISPDDSGIWDDRHGE
GFAPITRFIAEQGAVPGIQLAHAGRKASTDLPWRGGLPLGPEARGWQPVAPSPRPFAADYPVPRELTVEEMDDVVSQFRD
GAQRALAAGFQVVEIHMAHGYLLHEFLSPLSNRRTDDFGGSLENRIRLPLRVTRAVREVWPADLPLFVRISATDWVEGGW
DLDQSVVLARKLREAGVDLVDCSAGFLTPDAVIPFGSGYQTPFATAIRREAGIPTGTVGFITDPAQAEQIVATGLADAVL
LAREMLRDPYWPLHAARSLGVNVPWPPQYERAKLP

Sequences:

>Translated_355_residues
MSALFTPFTLRSVTFRNRIFVSPMCQYSSLDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSPEGRISPDDSGIWDDRHGE
GFAPITRFIAEQGAVPGIQLAHAGRKASTDLPWRGGLPLGPEARGWQPVAPSPRPFAADYPVPRELTVEEMDDVVSQFRD
GAQRALAAGFQVVEIHMAHGYLLHEFLSPLSNRRTDDFGGSLENRIRLPLRVTRAVREVWPADLPLFVRISATDWVEGGW
DLDQSVVLARKLREAGVDLVDCSAGFLTPDAVIPFGSGYQTPFATAIRREAGIPTGTVGFITDPAQAEQIVATGLADAVL
LAREMLRDPYWPLHAARSLGVNVPWPPQYERAKLP
>Mature_354_residues
SALFTPFTLRSVTFRNRIFVSPMCQYSSLDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSPEGRISPDDSGIWDDRHGEG
FAPITRFIAEQGAVPGIQLAHAGRKASTDLPWRGGLPLGPEARGWQPVAPSPRPFAADYPVPRELTVEEMDDVVSQFRDG
AQRALAAGFQVVEIHMAHGYLLHEFLSPLSNRRTDDFGGSLENRIRLPLRVTRAVREVWPADLPLFVRISATDWVEGGWD
LDQSVVLARKLREAGVDLVDCSAGFLTPDAVIPFGSGYQTPFATAIRREAGIPTGTVGFITDPAQAEQIVATGLADAVLL
AREMLRDPYWPLHAARSLGVNVPWPPQYERAKLP

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=336, Percent_Identity=31.25, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789463, Length=341, Percent_Identity=28.7390029325513, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17559804, Length=244, Percent_Identity=30.327868852459, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=245, Percent_Identity=29.3877551020408, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=254, Percent_Identity=29.5275590551181, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=253, Percent_Identity=26.8774703557312, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=279, Percent_Identity=25.4480286738351, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540738, Length=270, Percent_Identity=26.2962962962963, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=343, Percent_Identity=26.530612244898, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=219, Percent_Identity=30.1369863013699, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=222, Percent_Identity=28.3783783783784, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38747; Mature: 38616

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFTPFTLRSVTFRNRIFVSPMCQYSSLDGMPTDWHLVHLGSRAVGGAGLVMVEATAV
CCCCCCCHHHHHHHHCCEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEE
SPEGRISPDDSGIWDDRHGEGFAPITRFIAEQGAVPGIQLAHAGRKASTDLPWRGGLPLG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
PEARGWQPVAPSPRPFAADYPVPRELTVEEMDDVVSQFRDGAQRALAAGFQVVEIHMAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
YLLHEFLSPLSNRRTDDFGGSLENRIRLPLRVTRAVREVWPADLPLFVRISATDWVEGGW
HHHHHHHHHHHCCCCCCCCCCCHHHEECHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
DLDQSVVLARKLREAGVDLVDCSAGFLTPDAVIPFGSGYQTPFATAIRREAGIPTGTVGF
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
ITDPAQAEQIVATGLADAVLLAREMLRDPYWPLHAARSLGVNVPWPPQYERAKLP
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SALFTPFTLRSVTFRNRIFVSPMCQYSSLDGMPTDWHLVHLGSRAVGGAGLVMVEATAV
CCCCCCHHHHHHHHCCEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEE
SPEGRISPDDSGIWDDRHGEGFAPITRFIAEQGAVPGIQLAHAGRKASTDLPWRGGLPLG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
PEARGWQPVAPSPRPFAADYPVPRELTVEEMDDVVSQFRDGAQRALAAGFQVVEIHMAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
YLLHEFLSPLSNRRTDDFGGSLENRIRLPLRVTRAVREVWPADLPLFVRISATDWVEGGW
HHHHHHHHHHHCCCCCCCCCCCHHHEECHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
DLDQSVVLARKLREAGVDLVDCSAGFLTPDAVIPFGSGYQTPFATAIRREAGIPTGTVGF
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
ITDPAQAEQIVATGLADAVLLAREMLRDPYWPLHAARSLGVNVPWPPQYERAKLP
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA