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The map label for this gene is htpG

Identifier: 78223699

GI number: 78223699

Start: 2840812

End: 2842764

Strand: Direct

Name: htpG

Synonym: Gmet_2498

Alternate gene names: 78223699

Gene position: 2840812-2842764 (Clockwise)

Preceding gene: 78223690

Following gene: 78223700

Centisome position: 71.07

GC content: 60.93

Gene sequence:

>1953_bases
ATGACGAAGACCACCAAGAAATTCGAAACCGAGGTCCAGCAGCTCCTCGATCTCGTAATTCACTCCCTTTACTCCAACAA
GGACATCTTCCTCCGGGAACTCATCTCCAACTCTTCCGACGCCATCGACAAGGTCCTCTTCGAGGCTCACCAGAATGCGG
CGGTCATTGAGGGAGAGCCGGAAGGGAAAATCAAGCTGATCCCCGACAAAGAGGCCGGCACCATCACCATCCGCGACAAC
GGGGTCGGCATGACCATGGAGGAGGTGGAGAAGAACATCGGCACCATCGCCCATTCGGGGACCAAGGCGTTCCTGGCGAA
CCTGAAGGAGCAGAACGTGTCCGAGCACCCGGAGCTGATCGGCCAGTTCGGGGTCGGCTTCTACGCTTCGTTCATGGTGG
CCGACCGGGTCACCCTCGTCACCCGCCGTGCCGGCCAGGACAAGGCCGCCGGGGTCCGCTGGGAGTCCACCGGCGACGGC
ACCTACACCGTTGAAGAAGCAGTCAAGGAGACCCGCGGCACCGAAATCACCCTCCACCTGAAAGAAGAGATGAAGGAATA
TCTCGACGAGTGGAAGATCCGCTCCATCGTACGTAAATACTCCGACTACGTCCAGTACCCCGTCGTCATGGATGTGACCC
GGACCGAAGTCCCGAAAGGGGTGAACGGCGAGGAAATCGAAGGGGCCGGCACCATCGAGAAAACTGTGGAAGAGACTCTC
AACTCCATGAAGGCCATCTGGGCCCGCGCCAAGAGCGAAGTGACCGAGGAGGAGTACGAGGAGTTCTACAAGCACGTCTC
CCACGATTTCGAGAAACCCCTCAAGACCATCCACTATTCGGCCGAAGGGGTGAGCGAGTTCAAGGCACTCCTCTACCTGC
CGGCCCACAAACCCTTCGACCTCTTCATGCCCGAGCGCAAGAAAGGGGTCCAGCTCTACGTGCGCCGGGTCTTCATCACC
GACTCCTGCGAGCAGCTCATCCCCGACTACCTCCGCTTCGTGAAGGGGGTGGTGGACTCCAGCGACCTGCCACTCAACGT
GTCGCGGGAAATCCTCCAGGAAGATGTCCAGATCAAGCGGATCCAGAAAAGCCTCGTTTCCAAGATCATCTCCACCCTCT
CAGAAATGCGGGAGAAGGAGGCCGACGACTACCTCGCCTTCTACAAGGAGTTCGGCCAGGTCCTCAAGGAAGGGGTCCAC
TTCGATTACGCCAACCGGGAGAAGCTCCAGGACCTCCTCCTCTTCGAAAGCACCAGGACCGAGGCGGGGAAATTCACCTC
CCTCAAGGAGTACGTGGAGCGGATGCCCGCGGGGCAGGAAGAGATCTACTTCATCACTGGCACGAGCCGCACGGCCCTGG
AGCAGTCCCCCCACCTGGAGATCTTCCGGAAGAAGGAATACGAGGTCCTCTTCCTGACCGATCCCGTGGACGAGTGGGTG
GTGCAGGGGGTCACGGAGTACGACGGCAAGAAGCTCAAGGCCGTGGACCGGGGCGATGTCATCCCCGCCACCGAAGAGGA
GAAGAAGGAGCAGGAGGCCAAGCGGGAAGAGGCGTTCAAGCAGTACGGCGACCTCCTCTCCTTCGTGAAGGAGAAGCTCG
ACGCGCGGGTGAAGGAAGTGCGCCTTTCCAGCCGCCTCACCGACAGCGCCTGCTGCCTCGTGGCCGACGAGCACGGTCTC
AACGCCAACATGGAGCGGATTCTCCGGGCCATGAACCAGGATGTCCCCGAGTCGAAGCGGATTCTGGAGCTGAACCCGGA
TCACCCCCTCATGCAGGTGATGGCAAACCTCTTTGCCCGGGACAAGGCCAACCCGCGCCTGGGCGACTACTGCGACCTCC
TCTACGACCAGGCTCTGCTCACCGAAGGCTCGCCCATCAGCGACCCGCTCCGGTTCACGCGGCTCGTGGCGGAGCTGATG
GTGGCGGACGGGAAAGCGGCTGCGGGGGAGTAA

Upstream 100 bases:

>100_bases
GACAAAAAGTGTCGGCGCTCCCCTTGAAAAATCCCGGAGTGATAGTTAGGTTAGGGGAGTTCTGTCATCACCACACCGAC
ACAAAGGAGAAGACACCCCC

Downstream 100 bases:

>100_bases
TCGCAAGAACATAGACGGAACAAAGGGGAGTCGGTGACGGCTCCCCTTTGTCGTTTGCGCGGTGTTGGCAATGAGATGCT
TGCATAATGCATCATAGTAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MTKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEPEGKIKLIPDKEAGTITIRDN
GVGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELIGQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDG
TYTVEEAVKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETL
NSMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFIT
DSCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVH
FDYANREKLQDLLLFESTRTEAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWV
VQGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEVRLSSRLTDSACCLVADEHGL
NANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFARDKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELM
VADGKAAAGE

Sequences:

>Translated_650_residues
MTKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEPEGKIKLIPDKEAGTITIRDN
GVGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELIGQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDG
TYTVEEAVKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETL
NSMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFIT
DSCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVH
FDYANREKLQDLLLFESTRTEAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWV
VQGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEVRLSSRLTDSACCLVADEHGL
NANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFARDKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELM
VADGKAAAGE
>Mature_649_residues
TKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEPEGKIKLIPDKEAGTITIRDNG
VGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELIGQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDGT
YTVEEAVKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETLN
SMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFITD
SCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVHF
DYANREKLQDLLLFESTRTEAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWVV
QGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEVRLSSRLTDSACCLVADEHGLN
ANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFARDKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELMV
ADGKAAAGE

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=671, Percent_Identity=38.4500745156483, Blast_Score=464, Evalue=1e-130,
Organism=Homo sapiens, GI154146191, Length=675, Percent_Identity=39.2592592592593, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI153792590, Length=675, Percent_Identity=39.2592592592593, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI4507677, Length=663, Percent_Identity=39.0648567119155, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI155722983, Length=649, Percent_Identity=34.5146379044684, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1786679, Length=639, Percent_Identity=46.9483568075117, Blast_Score=571, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17559162, Length=658, Percent_Identity=40.1215805471125, Blast_Score=472, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17542208, Length=657, Percent_Identity=37.8995433789954, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=654, Percent_Identity=34.7094801223242, Blast_Score=345, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=37.5286041189931, Blast_Score=279, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6323840, Length=683, Percent_Identity=39.0922401171303, Blast_Score=460, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=687, Percent_Identity=39.4468704512373, Blast_Score=460, Evalue=1e-130,
Organism=Drosophila melanogaster, GI17647529, Length=706, Percent_Identity=39.943342776204, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=38.9955686853767, Blast_Score=419, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24586016, Length=624, Percent_Identity=36.2179487179487, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_GEOMG (Q39SQ3)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385446.1
- ProteinModelPortal:   Q39SQ3
- STRING:   Q39SQ3
- GeneID:   3738984
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2498
- NMPDR:   fig|269799.3.peg.2664
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q39SQ3
- ProtClustDB:   PRK05218
- BioCyc:   GMET269799:GMET_2498-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 74044; Mature: 73913

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEP
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCC
EGKIKLIPDKEAGTITIRDNGVGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELI
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
GQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDGTYTVEEAVKETRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEEH
KEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHH
NSMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCC
LFMPERKKGVQLYVRRVFITDSCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVHFDYANREKLQDLLLFESTRT
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
EAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWV
CCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCHHHEECCCCEEEEEECCHHHHH
VQGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEV
HHCHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSSRLTDSACCLVADEHGLNANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFAR
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHC
DKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELMVADGKAAAGE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEP
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCC
EGKIKLIPDKEAGTITIRDNGVGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELI
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
GQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDGTYTVEEAVKETRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEEH
KEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHH
NSMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCC
LFMPERKKGVQLYVRRVFITDSCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVHFDYANREKLQDLLLFESTRT
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
EAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWV
CCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCCHHHEECCCCEEEEEECCHHHHH
VQGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEV
HHCHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSSRLTDSACCLVADEHGLNANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFAR
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHC
DKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELMVADGKAAAGE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA