Click here to switch to the map view.

The map label for this gene is kdpA

Identifier: 78223636

GI number: 78223636

Start: 2753856

End: 2755616

Strand: Direct

Name: kdpA

Synonym: Gmet_2433

Alternate gene names: 78223636

Gene position: 2753856-2755616 (Clockwise)

Preceding gene: 78223616

Following gene: 78223637

Centisome position: 68.89

GC content: 61.67

Gene sequence:

>1761_bases
ATGACCCAGTACGAATGGCTGCAAACAACCCTTTTTCTAGTCCTCCTCTTGGCCGTGGTGAAGCCGATGGGGGCCTTCAT
GGCTAAGGTCTTCCAGGGGGAGCGCACCATGCTGTCGCCACTCCTCGTCCCGTGCGAGAACCTCCTCTACCGGATCTGCG
GAGTGAACCGTGACGAAGAGATGGACTGGAAGCGGTACGCCGTCGCCGTGCTCCTTTTCAATCTGGCGCTTTTTGTCTCG
CTCTTCGCTATCCTGATGCTGCAGCACCTGCTGCCGCTCAACCCGCAGAAGTTCCCGGCCTACACCTGGCAACTGGCCCT
CAACACCGCTATCAGCTTCGTCACCAACACCAACTGGCAGGCCTACAGCGGTGAATCGGCGGCCAGCTACTTCACCCAGA
CGGTGGGGCTGGCGGTGCACAACTTCGTCTCCGCCGCCACCGGCATTGCCGTGGCGATTGCGGTGATCCGGGGCTTTGCC
CGACGCAGGACCTCGATGCTGGGTAACTTCTGGGTCGACATGACCCGCTGCACCCTCTATGTCCTGCTGCCCATTTCCCT
TATTGGTGCACTCATCCTGGTTTCCCAGGGGGTGATCCAAAACTTCAGCGATTACAAAACAGTCCCCCTGGTCCAGCCCA
TCACCTACGACAAGCCGAAGGCGGACGGCAAGGGGAATCCAGTCACCGGGCGCGTGACCGTCAAAGATATCACCATTCCC
ATGGGTCCGGTCGCGTCCCAGGAAGCGATCAAAGAACTGGGGACCAACGGCGGCGGCTTCTTCAACGCCAACTCGGCCCA
TCCCTATGAAAACCCCACACCCATTTCCAACATGGTTGAGATCTTCCTGATCCTCCTCATCCCGTTCGCCCTCACCTCCA
CCTTCGGCGTCATGGTGGGAAATACCCGCCAGGGGTGGGCGATCCTGGGGGTGATGCTCCTGATGATGGCGATCTCCTTT
GCCGTGCTGCAAGGCGTGGAAACGAGCGGCAATCCCCTCGTGGCCAAGCTGGGCGTCCACGGTGTCAACATGGAGGGAAA
GGAGGTCCGCTTTGGGCTGGCCGGCGCGAGCCTCTTCACGGTGGCCACCACCGGTACCTCCTGCGGTGCGGTGGCCACCA
TGCACGACTCCCTCACCCCCCTCGGCGGCATGATCCCCCTGGGCCTGATACTTCTGGGCGAAATCGCTCCCGGCGGGGTC
GGCTCCGGGCTCTACACCATGCTCGCCTTCGTGGTGATCGCAGTCTTCGTGGCAGGGCTGATGATCGGCAGGACGCCGGA
GTTTCTGGGGAAGAAGATCGAGGTGCGCGAGATGTGGATGTCGATCATCACGGTCCTGGCAGCAGGGGTTGTGGTGCTGA
TCCTTTCGGGCGTCGCCATGATCACGCCTCAAGCCGTGGCCTCCAAGGCCAACCCCGGCGCCCATGGCCTGTCCGAGGTG
CTGTACGCCTTTGCCTCCATGGCCAACAACAACGGCAGCGCCTTTGCCGGGCTGAACGCCAACGTCGATTTCTATACCAT
TCTGGGTTCCCTGGCCATGCTGGTCGGGCGCTTTGCCCCAGCCGTCGCCGTGCTCGCCATGGCCGGTTCCCTGGCGGAGA
AAAAGTACGTCCCACCCAGCCTGGGGACGCTTCCCACCGACAAGGTTCCCTTTGCCCTCTGGCTCATGCTGGTAATTCTG
ATCGTGGGCGCACTGACCTTTTTCCCGGCCCTGTCGCTTGGCCCGCTCGTCGAGCATCTGACCATGCTGGGAGGTAAATA
A

Upstream 100 bases:

>100_bases
CGCGAACAACGGTGGGAAGTCCGCACCCGGCCTACCCCCTTTCGCCGACGTGATCAACAGGTACAATAAGTACGTTGGCA
TCCGAAACGGAGACCAAATC

Downstream 100 bases:

>100_bases
TCCATGTCGATACACAAGCCTGACCCGATCTCCATCTTCGACAGCCGGATTATGAAACCCGCGCTGATCGATTCCTTCAA
AAAGCTCGATCCCCGGGAAC

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MTQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEEMDWKRYAVAVLLFNLALFVS
LFAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQAYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFA
RRRTSMLGNFWVDMTRCTLYVLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIP
MGPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVGNTRQGWAILGVMLLMMAISF
AVLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFTVATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGV
GSGLYTMLAFVVIAVFVAGLMIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEV
LYAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPSLGTLPTDKVPFALWLMLVIL
IVGALTFFPALSLGPLVEHLTMLGGK

Sequences:

>Translated_586_residues
MTQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEEMDWKRYAVAVLLFNLALFVS
LFAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQAYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFA
RRRTSMLGNFWVDMTRCTLYVLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIP
MGPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVGNTRQGWAILGVMLLMMAISF
AVLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFTVATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGV
GSGLYTMLAFVVIAVFVAGLMIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEV
LYAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPSLGTLPTDKVPFALWLMLVIL
IVGALTFFPALSLGPLVEHLTMLGGK
>Mature_585_residues
TQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEEMDWKRYAVAVLLFNLALFVSL
FAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQAYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFAR
RRTSMLGNFWVDMTRCTLYVLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIPM
GPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVGNTRQGWAILGVMLLMMAISFA
VLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFTVATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGVG
SGLYTMLAFVVIAVFVAGLMIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEVL
YAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPSLGTLPTDKVPFALWLMLVILI
VGALTFFPALSLGPLVEHLTMLGGK

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=571, Percent_Identity=50.7880910683012, Blast_Score=540, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_GEOMG (Q39SW6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385383.1
- STRING:   Q39SW6
- GeneID:   3738448
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2433
- NMPDR:   fig|269799.3.peg.2874
- eggNOG:   COG2060
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- PhylomeDB:   Q39SW6
- ProtClustDB:   PRK05482
- BioCyc:   GMET269799:GMET_2433-MONOMER
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 62393; Mature: 62262

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf2507c8)-; HASH(0x11fa1b20)-; HASH(0x142dc7ac)-; HASH(0x11e04498)-; HASH(0x14308ddc)-; HASH(0x141cafac)-; HASH(0x13c4ba88)-; HASH(0x12abdd54)-; HASH(0x13e33f9c)-; HASH(0x13c3c0a4)-; HASH(0x13f81454)-; HASH(0x13dcf0bc)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MDWKRYAVAVLLFNLALFVSLFAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
AYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFARRRTSMLGNFWVDMTRCTLY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEC
MGPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVG
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC
NTRQGWAILGVMLLMMAISFAVLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEE
VATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGVGSGLYTMLAFVVIAVFVAGL
EEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEV
HHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHH
LYAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPS
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGTLPTDKVPFALWLMLVILIVGALTFFPALSLGPLVEHLTMLGGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MDWKRYAVAVLLFNLALFVSLFAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
AYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFARRRTSMLGNFWVDMTRCTLY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEC
MGPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVG
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC
NTRQGWAILGVMLLMMAISFAVLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEE
VATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGVGSGLYTMLAFVVIAVFVAGL
EEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEV
HHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHH
LYAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPS
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGTLPTDKVPFALWLMLVILIVGALTFFPALSLGPLVEHLTMLGGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA