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The map label for this gene is adrA [H]

Identifier: 78223628

GI number: 78223628

Start: 2743282

End: 2744343

Strand: Reverse

Name: adrA [H]

Synonym: Gmet_2425

Alternate gene names: 78223628

Gene position: 2744343-2743282 (Counterclockwise)

Preceding gene: 78223629

Following gene: 78223627

Centisome position: 68.65

GC content: 60.26

Gene sequence:

>1062_bases
ATGCTGCAATCGCACATTATGGCGGGAAACTGCACGGTAAAACCGGCACGGATGACACGCGCCCCCTATGCACGGCACGA
ACTGAAATCGACAAACTCCGGTTGTGACGAATCTCCTGCCGCCCTGGAGCGGCGCGTTGCCGAACTGCTTCTCGTGGCGG
ATTTTGGCGCTGTTGTCGGTTCCATCCTCGACCCCCGGCAGGTATGCGAGGTAGCATCTTCATGGCTCGGCGAGACTCTC
GGCTGGCAAATGCTCTCGGTTTGCTGCCATGATTTTTCCACCGGCACGATGAGGGGTGGGGCGGGACGCGGTCGTCATTT
GTCAAAAAAACGTCAGGAAGGCGCCACGTCCACGGTCTTTATCGCTGCCGCGCAGAAGGGGCTGAGCGATGCCGCCGACG
TCCGTACCATCCCTTTCCCCGACGGCTCGGGAACCCTCTCCCTCTCCCGTCAATCCCTGGCCGAAAGTCAATATTCCGAC
GAGTTCTTTGGGGGAGTTGTCGAAAACCTTGCCCGTTCCCTGGCCGCTGCCCGGGAGTGCGACCGGCTCAAGAACCTTTC
CATGCGCGATCATCTGACCGGACTTTACAACCGTCGGGTCTTCGAGGCGATGCTGGAAGTCGAGGCCCGGAAGCGGACCA
CAAAGCCGTTTTCGCTGCTTTTGATCGATCTCGACGACTTCAAACGCGTGAACGATACCTACGGTCACGGAGCCGGAGAC
CAGGTTCTCGTCGCCGTGGCGAAGATGCTGAGGCTCAGCTTCCGGAAGTCCGACGTCGTTTCCCGCTACGGCGGCGAGGA
GTTCGGAGTGCTGCTCCCCGATACGTCGCAGGATTCCGCCCGGGTGGTTGCGGAACGATTCCGGCAGAATGTGGCGACGC
TGTCGCTTCCCGTGAACAAAGAGAAGATAATGCCGACGGTCAGTGTCGGAATCGCCTCCGTGACGCTGCGCCTGGGAATT
GAGGTTGCCGATGTGATCGAAGAGGCCGACCGGGCTCTCTACCAGGCGAAGGTGACCGGCAAGAACCGCGTCTGCTCTTC
CCTGCTGGGAGAGAATTCGTAA

Upstream 100 bases:

>100_bases
ATAGCGTTAATGGACTGGCACTAAATATGCTTTTTTATGGCAATGGTTCCGTAATTGGCTGTAACTATTATGATGTTTTC
TTTCAGGGAGGAAATTGAAC

Downstream 100 bases:

>100_bases
ATTTTTAGTGTGGATCAAGCGTGTCGATGACGCCGTGGCCAGTGCCGCGGCGTTTTTTTTTGACACCATTTTGCTGCTGA
CAGCCAACGGGGAATATTAG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLQSHIMAGNCTVKPARMTRAPYARHELKSTNSGCDESPAALERRVAELLLVADFGAVVGSILDPRQVCEVASSWLGETL
GWQMLSVCCHDFSTGTMRGGAGRGRHLSKKRQEGATSTVFIAAAQKGLSDAADVRTIPFPDGSGTLSLSRQSLAESQYSD
EFFGGVVENLARSLAAARECDRLKNLSMRDHLTGLYNRRVFEAMLEVEARKRTTKPFSLLLIDLDDFKRVNDTYGHGAGD
QVLVAVAKMLRLSFRKSDVVSRYGGEEFGVLLPDTSQDSARVVAERFRQNVATLSLPVNKEKIMPTVSVGIASVTLRLGI
EVADVIEEADRALYQAKVTGKNRVCSSLLGENS

Sequences:

>Translated_353_residues
MLQSHIMAGNCTVKPARMTRAPYARHELKSTNSGCDESPAALERRVAELLLVADFGAVVGSILDPRQVCEVASSWLGETL
GWQMLSVCCHDFSTGTMRGGAGRGRHLSKKRQEGATSTVFIAAAQKGLSDAADVRTIPFPDGSGTLSLSRQSLAESQYSD
EFFGGVVENLARSLAAARECDRLKNLSMRDHLTGLYNRRVFEAMLEVEARKRTTKPFSLLLIDLDDFKRVNDTYGHGAGD
QVLVAVAKMLRLSFRKSDVVSRYGGEEFGVLLPDTSQDSARVVAERFRQNVATLSLPVNKEKIMPTVSVGIASVTLRLGI
EVADVIEEADRALYQAKVTGKNRVCSSLLGENS
>Mature_353_residues
MLQSHIMAGNCTVKPARMTRAPYARHELKSTNSGCDESPAALERRVAELLLVADFGAVVGSILDPRQVCEVASSWLGETL
GWQMLSVCCHDFSTGTMRGGAGRGRHLSKKRQEGATSTVFIAAAQKGLSDAADVRTIPFPDGSGTLSLSRQSLAESQYSD
EFFGGVVENLARSLAAARECDRLKNLSMRDHLTGLYNRRVFEAMLEVEARKRTTKPFSLLLIDLDDFKRVNDTYGHGAGD
QVLVAVAKMLRLSFRKSDVVSRYGGEEFGVLLPDTSQDSARVVAERFRQNVATLSLPVNKEKIMPTVSVGIASVTLRLGI
EVADVIEEADRALYQAKVTGKNRVCSSLLGENS

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=39.1304347826087, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=42.0731707317073, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87081881, Length=194, Percent_Identity=38.1443298969072, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=35.4037267080745, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=40.5063291139241, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=39.2857142857143, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787816, Length=195, Percent_Identity=34.8717948717949, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788381, Length=158, Percent_Identity=37.9746835443038, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=31.3513513513514, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=33.5294117647059, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081974, Length=161, Percent_Identity=29.8136645962733, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=213, Percent_Identity=29.5774647887324, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 38417; Mature: 38417

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSHIMAGNCTVKPARMTRAPYARHELKSTNSGCDESPAALERRVAELLLVADFGAVVG
CCCCCEECCCCEECHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SILDPRQVCEVASSWLGETLGWQMLSVCCHDFSTGTMRGGAGRGRHLSKKRQEGATSTVF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEE
IAAAQKGLSDAADVRTIPFPDGSGTLSLSRQSLAESQYSDEFFGGVVENLARSLAAAREC
EEEHHHCCCCHHCCEECCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DRLKNLSMRDHLTGLYNRRVFEAMLEVEARKRTTKPFSLLLIDLDDFKRVNDTYGHGAGD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCH
QVLVAVAKMLRLSFRKSDVVSRYGGEEFGVLLPDTSQDSARVVAERFRQNVATLSLPVNK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCHHEEECCCCH
EKIMPTVSVGIASVTLRLGIEVADVIEEADRALYQAKVTGKNRVCSSLLGENS
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MLQSHIMAGNCTVKPARMTRAPYARHELKSTNSGCDESPAALERRVAELLLVADFGAVVG
CCCCCEECCCCEECHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SILDPRQVCEVASSWLGETLGWQMLSVCCHDFSTGTMRGGAGRGRHLSKKRQEGATSTVF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEE
IAAAQKGLSDAADVRTIPFPDGSGTLSLSRQSLAESQYSDEFFGGVVENLARSLAAAREC
EEEHHHCCCCHHCCEECCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DRLKNLSMRDHLTGLYNRRVFEAMLEVEARKRTTKPFSLLLIDLDDFKRVNDTYGHGAGD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCH
QVLVAVAKMLRLSFRKSDVVSRYGGEEFGVLLPDTSQDSARVVAERFRQNVATLSLPVNK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCHHEEECCCCH
EKIMPTVSVGIASVTLRLGIEVADVIEEADRALYQAKVTGKNRVCSSLLGENS
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]