Click here to switch to the map view.

The map label for this gene is cheW [H]

Identifier: 78223624

GI number: 78223624

Start: 2734499

End: 2735035

Strand: Reverse

Name: cheW [H]

Synonym: Gmet_2421

Alternate gene names: 78223624

Gene position: 2735035-2734499 (Counterclockwise)

Preceding gene: 78223625

Following gene: 78223623

Centisome position: 68.42

GC content: 59.03

Gene sequence:

>537_bases
ATGCGCCTAGCCCCCAAAGTACAACCCCACGAGGAGGTTACCATGAGCGTTGCGGCAATAACGGAAACACGGCAGTATCT
GACCTTCAAGCTGGCGGAGGAGATCTTTGCCGTGGATGTGGCGAAGGTGCGCGAGATCCTCGAGTTCACAACCATTACGA
AGGTTCCCCAGACCCCCGATTTCATGCGCGGGGTCATCAATCTGCGGGGGAGCGTGGTGCCTGTCATGGACATGCGGCTC
AAGTTCGGCATGCCCGTGACGGAGAAGACCGTCAATACCTGCATCATTGTCGTGGAAGTGAACCACGAGGGCGAGACCAT
TATTATCGGTGCCCTGGCCGACTCGGTGCAGGAGGTCTTCGAGCTGGAGCCCGAGCAGATTGAGCCGGCTCCCCGGATCG
GGACCAAGCTCAACACCGACTTCATCCTGGGGATGGGGAAACATGATGGGCAGTTCATCATGATCCTCGACATCGACCGT
ACCTTCACCAGCGATGAGATTGCCACTGCCGGCGTCGTGGCGGGAGAGGCGGCGTAG

Upstream 100 bases:

>100_bases
AGAAATCGTGGAATTACAGATCAGGCAATTCCTGAACTGCTAAAGAATTTTCATTTTTTGCCGATATGTATCCTATAAGC
GAAGGTTCGGGGCGGGCCGC

Downstream 100 bases:

>100_bases
AGGCCGGGACCAGGGACCAGATCCTATTTATGCTCAATTCTGCCACTGACAACCGCCTTGCCACGGCGGCCATGAGCGAC
CGGGAGTTCTCGCGATTCGC

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRLAPKVQPHEEVTMSVAAITETRQYLTFKLAEEIFAVDVAKVREILEFTTITKVPQTPDFMRGVINLRGSVVPVMDMRL
KFGMPVTEKTVNTCIIVVEVNHEGETIIIGALADSVQEVFELEPEQIEPAPRIGTKLNTDFILGMGKHDGQFIMILDIDR
TFTSDEIATAGVVAGEAA

Sequences:

>Translated_178_residues
MRLAPKVQPHEEVTMSVAAITETRQYLTFKLAEEIFAVDVAKVREILEFTTITKVPQTPDFMRGVINLRGSVVPVMDMRL
KFGMPVTEKTVNTCIIVVEVNHEGETIIIGALADSVQEVFELEPEQIEPAPRIGTKLNTDFILGMGKHDGQFIMILDIDR
TFTSDEIATAGVVAGEAA
>Mature_178_residues
MRLAPKVQPHEEVTMSVAAITETRQYLTFKLAEEIFAVDVAKVREILEFTTITKVPQTPDFMRGVINLRGSVVPVMDMRL
KFGMPVTEKTVNTCIIVVEVNHEGETIIIGALADSVQEVFELEPEQIEPAPRIGTKLNTDFILGMGKHDGQFIMILDIDR
TFTSDEIATAGVVAGEAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=155, Percent_Identity=32.9032258064516, Blast_Score=110, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19645; Mature: 19645

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAPKVQPHEEVTMSVAAITETRQYLTFKLAEEIFAVDVAKVREILEFTTITKVPQTPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FMRGVINLRGSVVPVMDMRLKFGMPVTEKTVNTCIIVVEVNHEGETIIIGALADSVQEVF
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHH
ELEPEQIEPAPRIGTKLNTDFILGMGKHDGQFIMILDIDRTFTSDEIATAGVVAGEAA
CCCHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHCCEECCCCC
>Mature Secondary Structure
MRLAPKVQPHEEVTMSVAAITETRQYLTFKLAEEIFAVDVAKVREILEFTTITKVPQTPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FMRGVINLRGSVVPVMDMRLKFGMPVTEKTVNTCIIVVEVNHEGETIIIGALADSVQEVF
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHH
ELEPEQIEPAPRIGTKLNTDFILGMGKHDGQFIMILDIDRTFTSDEIATAGVVAGEAA
CCCHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]