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The map label for this gene is aroF [H]

Identifier: 78223578

GI number: 78223578

Start: 2684673

End: 2685740

Strand: Direct

Name: aroF [H]

Synonym: Gmet_2375

Alternate gene names: 78223578

Gene position: 2684673-2685740 (Clockwise)

Preceding gene: 78223577

Following gene: 78223582

Centisome position: 67.16

GC content: 61.24

Gene sequence:

>1068_bases
ATGACCAAGACAAGCAACCTGAAGGTCACGAGCATTACCCCCATCATCGCCCCTGCCGACCTGCGGCAAGTTTTCCCCCA
ATCGCTGGAAACAGCTGAATTCGTTAATGCGAGCCGGGCCCACATCAAGAACATCCTCAAGGGGAAAGACACCCGCCTCA
TGGTGGTGGTGGGCCCCTGTTCCATTCACGACCCCAAGGCCGCCCTCGACTATGCGGGGCGCCTTGCGCGACTCGCCAGC
GAACTCTCCGACCAGCTTTTCATCGTGATGCGGGTCTACTTCGAGAAGCCCCGCACCACCATCGGCTGGAAGGGGCTCAT
CAACGACCCCGACATGAACCACACCCACCAGATCTCCAAGGGACTCGGCATCGCGCGGCGGCTCCTGAACGACATCACCA
GCATGCTCCTCCCCGTGGCGTGCGAGATGCTCGATACCATCACCCCTGAATACCTGGCCGACTATATCTCGTGGGGCGCC
ATCGGCGCCCGGACCACCGAGAGCCAATCGCACCGGGAGATGGCGAGCGGCCTTTCCTTCCCCGTGGGCTTCAAAAATGG
CACTGACGGCAACCTGCAGATCGCCATCGACGCCATGAACGCGGCGCTCCACCCCCACAGCTTCCTCGGCATCAATCGGG
ATGGCAAGACCTCCATCATCCAGACCACCGGCAACCCGGACGTGCACATCGTCCTGCGTGGCGGCAAGAAGCCCAACTAC
TCTCCCGAGGACATCGCCAAGACCGAAGAGATGGTTGAAAAGGGGGGTATCTTCCCGACCATCATGGTTGATTGCAGCCA
CGGCAACTCGGAGAAGCGCCACGAGAAGCAGCCGGAGGTGCTTGACAGCATCGTCGACCAGATCGAGGCGGGCAATCGCT
CCATCTCGGGGGTCATGATCGAGAGCTTCCTCGAAGCGGGGAACCAGCCCATTCCCAAGGATCTGTCCCAACTCCGCTAC
GGGGTCTCCACCACCGACAAGTGCATCGACTGGAAGACCACCGAGGAAATCCTGCGCAAGGCCCATGAACGGCTCAAGCG
CTGCGGCGGAAGACCGATGCACGGTTGA

Upstream 100 bases:

>100_bases
ACCGTCCATGAGAGGGAATACATCCCGTTTGACTTTTGAGGGGGAAAGCGCTAGAGTGATTCGTCTCAAATCCCCATGAA
ATCAAAGGACAATTCCCGTA

Downstream 100 bases:

>100_bases
TCCCGGTCGCTCCTGGATACGCAGAGAGCCCCGCCAAAAGCGGGGCTCTTTTTTGGTTCATCCGGGAATTCCGGGGAAAG
CGGCTCTGATCTTGAGAAAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTKTSNLKVTSITPIIAPADLRQVFPQSLETAEFVNASRAHIKNILKGKDTRLMVVVGPCSIHDPKAALDYAGRLARLAS
ELSDQLFIVMRVYFEKPRTTIGWKGLINDPDMNHTHQISKGLGIARRLLNDITSMLLPVACEMLDTITPEYLADYISWGA
IGARTTESQSHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHPHSFLGINRDGKTSIIQTTGNPDVHIVLRGGKKPNY
SPEDIAKTEEMVEKGGIFPTIMVDCSHGNSEKRHEKQPEVLDSIVDQIEAGNRSISGVMIESFLEAGNQPIPKDLSQLRY
GVSTTDKCIDWKTTEEILRKAHERLKRCGGRPMHG

Sequences:

>Translated_355_residues
MTKTSNLKVTSITPIIAPADLRQVFPQSLETAEFVNASRAHIKNILKGKDTRLMVVVGPCSIHDPKAALDYAGRLARLAS
ELSDQLFIVMRVYFEKPRTTIGWKGLINDPDMNHTHQISKGLGIARRLLNDITSMLLPVACEMLDTITPEYLADYISWGA
IGARTTESQSHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHPHSFLGINRDGKTSIIQTTGNPDVHIVLRGGKKPNY
SPEDIAKTEEMVEKGGIFPTIMVDCSHGNSEKRHEKQPEVLDSIVDQIEAGNRSISGVMIESFLEAGNQPIPKDLSQLRY
GVSTTDKCIDWKTTEEILRKAHERLKRCGGRPMHG
>Mature_354_residues
TKTSNLKVTSITPIIAPADLRQVFPQSLETAEFVNASRAHIKNILKGKDTRLMVVVGPCSIHDPKAALDYAGRLARLASE
LSDQLFIVMRVYFEKPRTTIGWKGLINDPDMNHTHQISKGLGIARRLLNDITSMLLPVACEMLDTITPEYLADYISWGAI
GARTTESQSHREMASGLSFPVGFKNGTDGNLQIAIDAMNAALHPHSFLGINRDGKTSIIQTTGNPDVHIVLRGGKKPNYS
PEDIAKTEEMVEKGGIFPTIMVDCSHGNSEKRHEKQPEVLDSIVDQIEAGNRSISGVMIESFLEAGNQPIPKDLSQLRYG
VSTTDKCIDWKTTEEILRKAHERLKRCGGRPMHG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=341, Percent_Identity=55.7184750733138, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1786969, Length=344, Percent_Identity=53.4883720930233, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787996, Length=340, Percent_Identity=49.4117647058824, Blast_Score=347, Evalue=5e-97,
Organism=Saccharomyces cerevisiae, GI6320240, Length=343, Percent_Identity=51.8950437317784, Blast_Score=364, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319726, Length=337, Percent_Identity=51.3353115727003, Blast_Score=352, Evalue=4e-98,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39135; Mature: 39004

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSNLKVTSITPIIAPADLRQVFPQSLETAEFVNASRAHIKNILKGKDTRLMVVVGPC
CCCCCCEEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDPKAALDYAGRLARLASELSDQLFIVMRVYFEKPRTTIGWKGLINDPDMNHTHQISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
GLGIARRLLNDITSMLLPVACEMLDTITPEYLADYISWGAIGARTTESQSHREMASGLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
PVGFKNGTDGNLQIAIDAMNAALHPHSFLGINRDGKTSIIQTTGNPDVHIVLRGGKKPNY
CCCCCCCCCCCEEEEEEEHHHHCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCCC
SPEDIAKTEEMVEKGGIFPTIMVDCSHGNSEKRHEKQPEVLDSIVDQIEAGNRSISGVMI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHH
ESFLEAGNQPIPKDLSQLRYGVSTTDKCIDWKTTEEILRKAHERLKRCGGRPMHG
HHHHHCCCCCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKTSNLKVTSITPIIAPADLRQVFPQSLETAEFVNASRAHIKNILKGKDTRLMVVVGPC
CCCCCEEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDPKAALDYAGRLARLASELSDQLFIVMRVYFEKPRTTIGWKGLINDPDMNHTHQISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
GLGIARRLLNDITSMLLPVACEMLDTITPEYLADYISWGAIGARTTESQSHREMASGLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
PVGFKNGTDGNLQIAIDAMNAALHPHSFLGINRDGKTSIIQTTGNPDVHIVLRGGKKPNY
CCCCCCCCCCCEEEEEEEHHHHCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCCC
SPEDIAKTEEMVEKGGIFPTIMVDCSHGNSEKRHEKQPEVLDSIVDQIEAGNRSISGVMI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHH
ESFLEAGNQPIPKDLSQLRYGVSTTDKCIDWKTTEEILRKAHERLKRCGGRPMHG
HHHHHCCCCCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]