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The map label for this gene is 78223410

Identifier: 78223410

GI number: 78223410

Start: 2494946

End: 2496745

Strand: Reverse

Name: 78223410

Synonym: Gmet_2205

Alternate gene names: NA

Gene position: 2496745-2494946 (Counterclockwise)

Preceding gene: 78223411

Following gene: 78223409

Centisome position: 62.46

GC content: 57.67

Gene sequence:

>1800_bases
ATGGGCAAAAAGATAGAACTTACATCAAAGATCGGGCAGCTTTCTGACATCGGCAGATTCATCACACCAGGGGCGTTTGT
CGCTTTTGGCGGTGGCTGGAGCTGCAACAAGCCGATGGCTGTTATCCGTGAGATAGCCCGTCAGAATATAACCAACCTCA
AGGTAATGTCGATTGTCGGCGGTTGGGAGATGGAATGGCTGCTGGGTGCCGGGTGCGTCGATCACCTGGTCTTCAGTTTC
CTCAGCCTCGAGTTTTTCGGGCTTCCGGCCAATTTCCGACGCGTCGCTGAGAGACAGTTGGTAAAATTGACCGAGATCGA
AGGGTGCAGCATGATTAAGGGTCTTGAAGCCGCGCGTCTTGGCCTCCCCTTTGCTCCCTTCATGGGGCCCAAGGGGTCGG
ATATCGTCAAGGAGGCGCCGGAGCTATACAAGACCGTCGCCTGTCCCTTTACCGGCAAGGAGCTGACCGCCATCCAGGCT
ATTGTGCCTGATGTGGCGGTGATCCATGCCCAGCGCGCCGACGAGCAGGGTAACGTCCAGATCTTCGGCACATCGGCCTC
CGACCTTGACATGGCCATGGCCGCAAAGAAGACGATAGTCACGGTAGAGGAGATCGTCTCGGGAGACCAGATCCGGGCTG
ACAAAACTGCCACCAAGCTCTTCCGCACCGATGTCGACATGGTCATTCATGTCCCCTTCGGTGCCAGTCCCTGTAGTTCC
ATACCGTATTACTCTGCCCACCTCCTTCAGATGAACCGGGATGTGCAGGGGCTCAATCCGAAAACGGCCAAAGAGTATAT
CGCCGCAACGGTCGGAAAGAATGAGGACGAGTATTGGGCGAAGGCTGGCGGCGATGCCGCCAAGAAAAAGCTGCAATCCC
TCGCACGGCAGACAACCCGTGTTGAATGGCCCCAGAAGCTGGTTAACGATAAAGCCGAAGAGTATGAGGTCGCCGACCAG
ATGGTCACCAGCCTGGCCCGTACCATTGACGACGGGGATACGACGGTGCTCGGCTCATTCACCCCCCTGGCATACGCTGC
CTACAACCTGGCAAAACTGACCACGGCCCCCAACTCGTTCATGGTCGGCTACAGCGGCGTGGATGCCTATCCGTTCCAGA
TGGGGTTCCATACATCGGAAGCGGCCTGTATCGGCAACTCGGCGGGACTCTGGTCCATGACCGAATGCATCGAGGCCCTC
CATTTCCGGGGTACCGGCGACGTGGAGGCGGTGTCGAGCGCCCAGATGGATGCCAACGGCGACATCAACATCTCCTGGCT
GCCGATGCCGGTCATGGATGCCGAGGGGAAGCCAACCGGCGAATTCAATGCCAGGGGACTCAGGCTCCCCGGCGGGGCCG
GTGCGCCGGTCGTCTTCGGACTGCACCGCAAGTCGGTTGCCTACTTTCCCAACCACTCGAAACAGATTTTTGTCCCCAAG
GTGAATTATATAACTGGCACGCGGGTCTACCTGAACGATGAAGAGCGGTTGGCCCAGGGACTGCAGCCGGGACCGATGAT
CGTGGTGACCAACCTGTGCGTCATGGAAATGAGGGAACGTGGCAAGTGGAAGATCGTCTCCCTTCATAAAGGGGTTACAC
CGGAAGATGTGGTCAAAAACACCGGCTTTCCCGTGGAAATCGCGGCCGATTGCCCGGTCACGGAGCCTCCGACCAAGCAG
GAACAGGAATTGATCGGCAAGATCGATCCCAAGGGGATTCGCCGGCTCGATTTCATGAGTGGAAAGGAACGGGCCGTCAA
GCTTCCCGATATCCTTCAAGAGGAATGGGATTCAGTGTAG

Upstream 100 bases:

>100_bases
GCGGTACTGCCGCTGGATGGAGGGTGGTCGGCCGGCTAGTGACGGTGTTTTCTCCCGGCTACAAACTGCTACTTACGTAA
CGAGAGGAGATAGGAAGCCC

Downstream 100 bases:

>100_bases
CGGGGAACCAGGCCCCCTCGAAGGGGGAATATTGATACGATTATGGCTGTTAGCCGAAAGGAGATGACTAACAATGAAGT
ATACCGTTTTCAAGGTTGAA

Product: coenzyme A transferase

Products: acetate; glutaconyl-1-CoA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MGKKIELTSKIGQLSDIGRFITPGAFVAFGGGWSCNKPMAVIREIARQNITNLKVMSIVGGWEMEWLLGAGCVDHLVFSF
LSLEFFGLPANFRRVAERQLVKLTEIEGCSMIKGLEAARLGLPFAPFMGPKGSDIVKEAPELYKTVACPFTGKELTAIQA
IVPDVAVIHAQRADEQGNVQIFGTSASDLDMAMAAKKTIVTVEEIVSGDQIRADKTATKLFRTDVDMVIHVPFGASPCSS
IPYYSAHLLQMNRDVQGLNPKTAKEYIAATVGKNEDEYWAKAGGDAAKKKLQSLARQTTRVEWPQKLVNDKAEEYEVADQ
MVTSLARTIDDGDTTVLGSFTPLAYAAYNLAKLTTAPNSFMVGYSGVDAYPFQMGFHTSEAACIGNSAGLWSMTECIEAL
HFRGTGDVEAVSSAQMDANGDINISWLPMPVMDAEGKPTGEFNARGLRLPGGAGAPVVFGLHRKSVAYFPNHSKQIFVPK
VNYITGTRVYLNDEERLAQGLQPGPMIVVTNLCVMEMRERGKWKIVSLHKGVTPEDVVKNTGFPVEIAADCPVTEPPTKQ
EQELIGKIDPKGIRRLDFMSGKERAVKLPDILQEEWDSV

Sequences:

>Translated_599_residues
MGKKIELTSKIGQLSDIGRFITPGAFVAFGGGWSCNKPMAVIREIARQNITNLKVMSIVGGWEMEWLLGAGCVDHLVFSF
LSLEFFGLPANFRRVAERQLVKLTEIEGCSMIKGLEAARLGLPFAPFMGPKGSDIVKEAPELYKTVACPFTGKELTAIQA
IVPDVAVIHAQRADEQGNVQIFGTSASDLDMAMAAKKTIVTVEEIVSGDQIRADKTATKLFRTDVDMVIHVPFGASPCSS
IPYYSAHLLQMNRDVQGLNPKTAKEYIAATVGKNEDEYWAKAGGDAAKKKLQSLARQTTRVEWPQKLVNDKAEEYEVADQ
MVTSLARTIDDGDTTVLGSFTPLAYAAYNLAKLTTAPNSFMVGYSGVDAYPFQMGFHTSEAACIGNSAGLWSMTECIEAL
HFRGTGDVEAVSSAQMDANGDINISWLPMPVMDAEGKPTGEFNARGLRLPGGAGAPVVFGLHRKSVAYFPNHSKQIFVPK
VNYITGTRVYLNDEERLAQGLQPGPMIVVTNLCVMEMRERGKWKIVSLHKGVTPEDVVKNTGFPVEIAADCPVTEPPTKQ
EQELIGKIDPKGIRRLDFMSGKERAVKLPDILQEEWDSV
>Mature_598_residues
GKKIELTSKIGQLSDIGRFITPGAFVAFGGGWSCNKPMAVIREIARQNITNLKVMSIVGGWEMEWLLGAGCVDHLVFSFL
SLEFFGLPANFRRVAERQLVKLTEIEGCSMIKGLEAARLGLPFAPFMGPKGSDIVKEAPELYKTVACPFTGKELTAIQAI
VPDVAVIHAQRADEQGNVQIFGTSASDLDMAMAAKKTIVTVEEIVSGDQIRADKTATKLFRTDVDMVIHVPFGASPCSSI
PYYSAHLLQMNRDVQGLNPKTAKEYIAATVGKNEDEYWAKAGGDAAKKKLQSLARQTTRVEWPQKLVNDKAEEYEVADQM
VTSLARTIDDGDTTVLGSFTPLAYAAYNLAKLTTAPNSFMVGYSGVDAYPFQMGFHTSEAACIGNSAGLWSMTECIEALH
FRGTGDVEAVSSAQMDANGDINISWLPMPVMDAEGKPTGEFNARGLRLPGGAGAPVVFGLHRKSVAYFPNHSKQIFVPKV
NYITGTRVYLNDEERLAQGLQPGPMIVVTNLCVMEMRERGKWKIVSLHKGVTPEDVVKNTGFPVEIAADCPVTEPPTKQE
QELIGKIDPKGIRRLDFMSGKERAVKLPDILQEEWDSV

Specific function: Unknown

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.12

Molecular weight: Translated: 65351; Mature: 65220

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKIELTSKIGQLSDIGRFITPGAFVAFGGGWSCNKPMAVIREIARQNITNLKVMSIVG
CCCEEEHHHHHCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
GWEMEWLLGAGCVDHLVFSFLSLEFFGLPANFRRVAERQLVKLTEIEGCSMIKGLEAARL
CCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHC
GLPFAPFMGPKGSDIVKEAPELYKTVACPFTGKELTAIQAIVPDVAVIHAQRADEQGNVQ
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHEEEHHCCCCCCCEE
IFGTSASDLDMAMAAKKTIVTVEEIVSGDQIRADKTATKLFRTDVDMVIHVPFGASPCSS
EEECCCCHHHHHHHHHHHHEEHHHHHCCCCEECHHHHHHHHHCCCCEEEECCCCCCCCCC
IPYYSAHLLQMNRDVQGLNPKTAKEYIAATVGKNEDEYWAKAGGDAAKKKLQSLARQTTR
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
VEWPQKLVNDKAEEYEVADQMVTSLARTIDDGDTTVLGSFTPLAYAAYNLAKLTTAPNSF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHEEECCCCE
MVGYSGVDAYPFQMGFHTSEAACIGNSAGLWSMTECIEALHFRGTGDVEAVSSAQMDANG
EEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCC
DINISWLPMPVMDAEGKPTGEFNARGLRLPGGAGAPVVFGLHRKSVAYFPNHSKQIFVPK
CEEEEEECCCEECCCCCCCCCCCCCEEECCCCCCCCEEEEECCCEEEECCCCCCEEEEEE
VNYITGTRVYLNDEERLAQGLQPGPMIVVTNLCVMEMRERGKWKIVSLHKGVTPEDVVKN
ECEEECCEEEECCHHHHHCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHHHHC
TGFPVEIAADCPVTEPPTKQEQELIGKIDPKGIRRLDFMSGKERAVKLPDILQEEWDSV
CCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCEEECHHHHHHHHCCC
>Mature Secondary Structure 
GKKIELTSKIGQLSDIGRFITPGAFVAFGGGWSCNKPMAVIREIARQNITNLKVMSIVG
CCEEEHHHHHCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
GWEMEWLLGAGCVDHLVFSFLSLEFFGLPANFRRVAERQLVKLTEIEGCSMIKGLEAARL
CCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHC
GLPFAPFMGPKGSDIVKEAPELYKTVACPFTGKELTAIQAIVPDVAVIHAQRADEQGNVQ
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHEEEHHCCCCCCCEE
IFGTSASDLDMAMAAKKTIVTVEEIVSGDQIRADKTATKLFRTDVDMVIHVPFGASPCSS
EEECCCCHHHHHHHHHHHHEEHHHHHCCCCEECHHHHHHHHHCCCCEEEECCCCCCCCCC
IPYYSAHLLQMNRDVQGLNPKTAKEYIAATVGKNEDEYWAKAGGDAAKKKLQSLARQTTR
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
VEWPQKLVNDKAEEYEVADQMVTSLARTIDDGDTTVLGSFTPLAYAAYNLAKLTTAPNSF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHEEECCCCE
MVGYSGVDAYPFQMGFHTSEAACIGNSAGLWSMTECIEALHFRGTGDVEAVSSAQMDANG
EEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCC
DINISWLPMPVMDAEGKPTGEFNARGLRLPGGAGAPVVFGLHRKSVAYFPNHSKQIFVPK
CEEEEEECCCEECCCCCCCCCCCCCEEECCCCCCCCEEEEECCCEEEECCCCCCEEEEEE
VNYITGTRVYLNDEERLAQGLQPGPMIVVTNLCVMEMRERGKWKIVSLHKGVTPEDVVKN
ECEEECCEEEECCHHHHHCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHHHHC
TGFPVEIAADCPVTEPPTKQEQELIGKIDPKGIRRLDFMSGKERAVKLPDILQEEWDSV
CCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; (E)-glutaconate

Specific reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]