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The map label for this gene is wzc [C]

Identifier: 78223389

GI number: 78223389

Start: 2467515

End: 2468744

Strand: Reverse

Name: wzc [C]

Synonym: Gmet_2183

Alternate gene names: 78223389

Gene position: 2468744-2467515 (Counterclockwise)

Preceding gene: 78223390

Following gene: 78223388

Centisome position: 61.76

GC content: 58.78

Gene sequence:

>1230_bases
ATGATGCTGCATTCAGAAAATTCAACTGACGATACCCGCACCTCGAAACCCCTGTTCACTCTGCTTGATTTCGCGGCCGT
AATCATCAAGCACTGGCGGCTGACTGCCTGCATCACCCTCGCTGCGGCCCTTGTCGCCGTGATTTACACGCTGATGCTGC
CGAACCTCTACACGGCACGGTCCATGATCCTGCCGCTGGAGGACGATCGCGAAGGGGTGGGAGCCGCTCTTGGCCAACTG
GCCGGCCTGGCCGGAGTCGGACGGATCGGGCTCGGCAACCCCTCCAAGGCCGACGTGTATCTGGCCATGCTCAATGGCGA
AACCATCAGGGACCCGCTCATTGACCGCTTCAGGCTGTTGGAAGCCTACGAGGCGAAGTACCGGACCGAAGCCTATGGAG
CGCTGGACAGAAATGTTGCGGTCACGGTGGGAAAAAAGGACGGCATCATCACCATTGCCGTGGATGACAGGGACCCCAGG
CGCGCGGCGGAGATGGCCAACGCCTACGTGGAGGAGTTGGGGAGGCTGGCAAATCGGCTCAACATGGCGTCTGCGGGCAA
TGACAGGATGTATCTGGAAAAACGGCTTGCCTCGGCCCGTGTCGATCTTGCCAAGGCTGAGGATGCGCTCAAGGCCTTTC
AGTCGAAAAACAAGGCCGTATCGGTAAGCGATCAGGCGAAAGCCACGATCGATGGCGTGGCGCAACTGCGTGCCCAGCTT
GCCGCCCAGGAAGTGCAACTTTCCGCTTACCGGAGCCAGTTCACCGATTCGAGCCAGGAAGTGAGAACGTCCAAGGCCGC
CATCGGCAGACTGCAGGCCCAGATCGCCAGGCTCGAAGGGAATGGCGGCGGAGGCAGCGCCATTCCGTCGGTGGGGAGCA
TGCCGCAGCTGGGACAGCAGTACCTGCGGCTGATGCGGGATTTCAAGATCCAGGAGACAATGGTTGAGCTGCTTGCAAAG
CAGTATGAAGTGGCAAGGATGTCCGAGGTCAAGGATGTTTCGCCGTTCCAGGTGCTCCAGGTGGCAAAAGTGCCCGAGAA
GAAAAGCAAACCCCATCGCACGCTGATCGTGCTGGTTGCCGCACTTACGGCGTTCCTCTGCTCGATCTACCTTTCGTTCG
TGCTCGAACATCTCGACAGGATGTCCGAGCAGGACAAGATGCGGTGGTTCGAGTTGAAAAGCCGGCTGTTGTTCTGGAAA
AAACAGAAGCTCACTTTGCAAAACGAATAG

Upstream 100 bases:

>100_bases
ATCCTCGGCAACCTGGCCCTTGCGGCCGGGGTGATAGTAGCGGCAGGTCTGTAGCGATGGCGGCGGAAAGGGAAAACCTA
CAAGGATTCGCGGAGTTCAT

Downstream 100 bases:

>100_bases
TGCCTGAAGGAATGCATGTTCGGGCGCTTGAATTGGAAAAATCATGCCCTTTCAAGCCATTACTCAAAACGGGATATCAG
AAATCTATGAACGACCGGCC

Product: lipopolysaccharide biosynthesis

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MMLHSENSTDDTRTSKPLFTLLDFAAVIIKHWRLTACITLAAALVAVIYTLMLPNLYTARSMILPLEDDREGVGAALGQL
AGLAGVGRIGLGNPSKADVYLAMLNGETIRDPLIDRFRLLEAYEAKYRTEAYGALDRNVAVTVGKKDGIITIAVDDRDPR
RAAEMANAYVEELGRLANRLNMASAGNDRMYLEKRLASARVDLAKAEDALKAFQSKNKAVSVSDQAKATIDGVAQLRAQL
AAQEVQLSAYRSQFTDSSQEVRTSKAAIGRLQAQIARLEGNGGGGSAIPSVGSMPQLGQQYLRLMRDFKIQETMVELLAK
QYEVARMSEVKDVSPFQVLQVAKVPEKKSKPHRTLIVLVAALTAFLCSIYLSFVLEHLDRMSEQDKMRWFELKSRLLFWK
KQKLTLQNE

Sequences:

>Translated_409_residues
MMLHSENSTDDTRTSKPLFTLLDFAAVIIKHWRLTACITLAAALVAVIYTLMLPNLYTARSMILPLEDDREGVGAALGQL
AGLAGVGRIGLGNPSKADVYLAMLNGETIRDPLIDRFRLLEAYEAKYRTEAYGALDRNVAVTVGKKDGIITIAVDDRDPR
RAAEMANAYVEELGRLANRLNMASAGNDRMYLEKRLASARVDLAKAEDALKAFQSKNKAVSVSDQAKATIDGVAQLRAQL
AAQEVQLSAYRSQFTDSSQEVRTSKAAIGRLQAQIARLEGNGGGGSAIPSVGSMPQLGQQYLRLMRDFKIQETMVELLAK
QYEVARMSEVKDVSPFQVLQVAKVPEKKSKPHRTLIVLVAALTAFLCSIYLSFVLEHLDRMSEQDKMRWFELKSRLLFWK
KQKLTLQNE
>Mature_409_residues
MMLHSENSTDDTRTSKPLFTLLDFAAVIIKHWRLTACITLAAALVAVIYTLMLPNLYTARSMILPLEDDREGVGAALGQL
AGLAGVGRIGLGNPSKADVYLAMLNGETIRDPLIDRFRLLEAYEAKYRTEAYGALDRNVAVTVGKKDGIITIAVDDRDPR
RAAEMANAYVEELGRLANRLNMASAGNDRMYLEKRLASARVDLAKAEDALKAFQSKNKAVSVSDQAKATIDGVAQLRAQL
AAQEVQLSAYRSQFTDSSQEVRTSKAAIGRLQAQIARLEGNGGGGSAIPSVGSMPQLGQQYLRLMRDFKIQETMVELLAK
QYEVARMSEVKDVSPFQVLQVAKVPEKKSKPHRTLIVLVAALTAFLCSIYLSFVLEHLDRMSEQDKMRWFELKSRLLFWK
KQKLTLQNE

Specific function: Required For The Extracellular Polysaccharide Colanic Acid Synthesis. The Autophosphorylated Form Is Inactive. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 45313; Mature: 45313

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLHSENSTDDTRTSKPLFTLLDFAAVIIKHWRLTACITLAAALVAVIYTLMLPNLYTAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SMILPLEDDREGVGAALGQLAGLAGVGRIGLGNPSKADVYLAMLNGETIRDPLIDRFRLL
HEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
EAYEAKYRTEAYGALDRNVAVTVGKKDGIITIAVDDRDPRRAAEMANAYVEELGRLANRL
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NMASAGNDRMYLEKRLASARVDLAKAEDALKAFQSKNKAVSVSDQAKATIDGVAQLRAQL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHH
AAQEVQLSAYRSQFTDSSQEVRTSKAAIGRLQAQIARLEGNGGGGSAIPSVGSMPQLGQQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
YLRLMRDFKIQETMVELLAKQYEVARMSEVKDVSPFQVLQVAKVPEKKSKPHRTLIVLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
ALTAFLCSIYLSFVLEHLDRMSEQDKMRWFELKSRLLFWKKQKLTLQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMLHSENSTDDTRTSKPLFTLLDFAAVIIKHWRLTACITLAAALVAVIYTLMLPNLYTAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SMILPLEDDREGVGAALGQLAGLAGVGRIGLGNPSKADVYLAMLNGETIRDPLIDRFRLL
HEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
EAYEAKYRTEAYGALDRNVAVTVGKKDGIITIAVDDRDPRRAAEMANAYVEELGRLANRL
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
NMASAGNDRMYLEKRLASARVDLAKAEDALKAFQSKNKAVSVSDQAKATIDGVAQLRAQL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHH
AAQEVQLSAYRSQFTDSSQEVRTSKAAIGRLQAQIARLEGNGGGGSAIPSVGSMPQLGQQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
YLRLMRDFKIQETMVELLAKQYEVARMSEVKDVSPFQVLQVAKVPEKKSKPHRTLIVLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
ALTAFLCSIYLSFVLEHLDRMSEQDKMRWFELKSRLLFWKKQKLTLQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]