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The map label for this gene is ubiE [C]

Identifier: 78223384

GI number: 78223384

Start: 2460081

End: 2461118

Strand: Reverse

Name: ubiE [C]

Synonym: Gmet_2177

Alternate gene names: 78223384

Gene position: 2461118-2460081 (Counterclockwise)

Preceding gene: 78223385

Following gene: 78223383

Centisome position: 61.57

GC content: 58.0

Gene sequence:

>1038_bases
ATGGATAACATCAGGATAACCACTGAACCCAGGCGTGACTGCTTGTTATGCGGTAGGAACGGGAATGCGCTCTACGAGGA
TCTGGGAGACAGGCTCTTCGGGGCGCCCGGTAAATGGACGCTTGAGAAGTGCGTTAATGATAACTGCGGCCTTGTTTGGT
TGAATCCTGCTCCCCGCAAGGATGAGATCTGGAAGGCGTACGCTTCCTACTACACCCACGGGGACAATCAGGCTCCCCCG
GCAGGCGTTGCGAAAAGAATATTCCATTGCGTCAGGGACTGCTATCTGGCCCTCAAATATGACTATTTCAACGAACTGCG
TCAGTCCCCACTGAGGTTTTTGGGAACACTTCTGTATCTCTTTCCGGGACGACGCGCCGATGTGGATTTCAGCGTGATGT
ACCTGCGAAGCAGGCCGGGGGGGCGATTGCTGGAAATCGGATGCGGCAGCGGCACGATGCTGAGCTACCTGGGATCGCTG
GGGTGGCGGACGGAAGGGATAGACGTTGACCCTTCGGCAGTTGCCAATGCCAGGAGCAAGGGGCTGAATGTGGCGCAGGG
CGACCTTCTGGAGCAGCCCTACGGGGACAACACCTTTGACGCCGTCATGATCAGCCACGTGATCGAGCATGTTCCCAATC
CTGTGGAACTGCTCACCGAGTGCTACCGGATATTGAAACCGGGCGGGGTGCTCAGTCTGGTAACCCCGAACGTCGAATCC
ATGGGCAGCCATCTCTTCGGGAGGCATTGGCTGCACCTGGACCCGCCCCGGCATCTGATCCTCTACAACGTCAGAACGAT
TCGGGCGCTGGCCCGCAAGGCCGGCTTCACCAACATGGAAATCAGGACCACCATCCGCGATGCCCACGCCCTTTTCTGGG
CAAGCTACTCCATCAGTAGACGGGGCACGTATGCCATGGGATCGCAACCGGGCCGGTCCGGCAGGCTGTTCATGCTGCTG
ATGCGGCTGGTGGAGTGGGGCCTGCTCAAAGTGTTCCCTCACAAGGGAGAGGAATTATCTCTCATGGGTGTCAAGTGA

Upstream 100 bases:

>100_bases
TCTTGATGAGGTCGCCGAACCTGGTTGGTGGACAACAGAGCAAGTATCTCCGACGGACCGGTGGCCAGACGATACTTGGC
CCCATCCGGAAAGCTAGAGC

Downstream 100 bases:

>100_bases
GTGCCATGCTGAAACTGTCTGTCGCCATATGCACCTACAACGGTGAACGGTTCCTCCGGGAGCAGCTGGACAGCATCGCC
CGCCAGACAAGACTGCCGGA

Product: ubiquinone/menaquinone biosynthesis methylase-like protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDNIRITTEPRRDCLLCGRNGNALYEDLGDRLFGAPGKWTLEKCVNDNCGLVWLNPAPRKDEIWKAYASYYTHGDNQAPP
AGVAKRIFHCVRDCYLALKYDYFNELRQSPLRFLGTLLYLFPGRRADVDFSVMYLRSRPGGRLLEIGCGSGTMLSYLGSL
GWRTEGIDVDPSAVANARSKGLNVAQGDLLEQPYGDNTFDAVMISHVIEHVPNPVELLTECYRILKPGGVLSLVTPNVES
MGSHLFGRHWLHLDPPRHLILYNVRTIRALARKAGFTNMEIRTTIRDAHALFWASYSISRRGTYAMGSQPGRSGRLFMLL
MRLVEWGLLKVFPHKGEELSLMGVK

Sequences:

>Translated_345_residues
MDNIRITTEPRRDCLLCGRNGNALYEDLGDRLFGAPGKWTLEKCVNDNCGLVWLNPAPRKDEIWKAYASYYTHGDNQAPP
AGVAKRIFHCVRDCYLALKYDYFNELRQSPLRFLGTLLYLFPGRRADVDFSVMYLRSRPGGRLLEIGCGSGTMLSYLGSL
GWRTEGIDVDPSAVANARSKGLNVAQGDLLEQPYGDNTFDAVMISHVIEHVPNPVELLTECYRILKPGGVLSLVTPNVES
MGSHLFGRHWLHLDPPRHLILYNVRTIRALARKAGFTNMEIRTTIRDAHALFWASYSISRRGTYAMGSQPGRSGRLFMLL
MRLVEWGLLKVFPHKGEELSLMGVK
>Mature_345_residues
MDNIRITTEPRRDCLLCGRNGNALYEDLGDRLFGAPGKWTLEKCVNDNCGLVWLNPAPRKDEIWKAYASYYTHGDNQAPP
AGVAKRIFHCVRDCYLALKYDYFNELRQSPLRFLGTLLYLFPGRRADVDFSVMYLRSRPGGRLLEIGCGSGTMLSYLGSL
GWRTEGIDVDPSAVANARSKGLNVAQGDLLEQPYGDNTFDAVMISHVIEHVPNPVELLTECYRILKPGGVLSLVTPNVES
MGSHLFGRHWLHLDPPRHLILYNVRTIRALARKAGFTNMEIRTTIRDAHALFWASYSISRRGTYAMGSQPGRSGRLFMLL
MRLVEWGLLKVFPHKGEELSLMGVK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 38879; Mature: 38879

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNIRITTEPRRDCLLCGRNGNALYEDLGDRLFGAPGKWTLEKCVNDNCGLVWLNPAPRK
CCCCEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEECCCCCH
DEIWKAYASYYTHGDNQAPPAGVAKRIFHCVRDCYLALKYDYFNELRQSPLRFLGTLLYL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPGRRADVDFSVMYLRSRPGGRLLEIGCGSGTMLSYLGSLGWRTEGIDVDPSAVANARSK
CCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GLNVAQGDLLEQPYGDNTFDAVMISHVIEHVPNPVELLTECYRILKPGGVLSLVTPNVES
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHH
MGSHLFGRHWLHLDPPRHLILYNVRTIRALARKAGFTNMEIRTTIRDAHALFWASYSISR
HHHHHHCCCCEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHEEEECCC
RGTYAMGSQPGRSGRLFMLLMRLVEWGLLKVFPHKGEELSLMGVK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCEEEEECCC
>Mature Secondary Structure
MDNIRITTEPRRDCLLCGRNGNALYEDLGDRLFGAPGKWTLEKCVNDNCGLVWLNPAPRK
CCCCEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEECCCCCH
DEIWKAYASYYTHGDNQAPPAGVAKRIFHCVRDCYLALKYDYFNELRQSPLRFLGTLLYL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPGRRADVDFSVMYLRSRPGGRLLEIGCGSGTMLSYLGSLGWRTEGIDVDPSAVANARSK
CCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GLNVAQGDLLEQPYGDNTFDAVMISHVIEHVPNPVELLTECYRILKPGGVLSLVTPNVES
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHH
MGSHLFGRHWLHLDPPRHLILYNVRTIRALARKAGFTNMEIRTTIRDAHALFWASYSISR
HHHHHHCCCCEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHEEEECCC
RGTYAMGSQPGRSGRLFMLLMRLVEWGLLKVFPHKGEELSLMGVK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]