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The map label for this gene is xylR [H]

Identifier: 78223306

GI number: 78223306

Start: 2362565

End: 2364289

Strand: Reverse

Name: xylR [H]

Synonym: Gmet_2099

Alternate gene names: 78223306

Gene position: 2364289-2362565 (Counterclockwise)

Preceding gene: 78223319

Following gene: 78223305

Centisome position: 59.15

GC content: 57.45

Gene sequence:

>1725_bases
ATGACTAAACAGCGACGTTCCGATAAGCCTGGCTGCACATTGACGGACGGCGATCTCCTCGGACGGGTGCATTTCTGTAG
GGAATCAGGGAATATTTGGCTGCACGAGCATCGCATGCTCCTGGTGCATGCCGAGGCGCAGGCCACTCTGCGGAGGGAGC
TGATTGATACGCTCGGCATAGAGCGCGTACAGGGGCTGCTCACGCGCATGGGGTACGCGGCCGGCATGCACGATGCCGAA
CTCGTCTGTACGCGCGTTGAGGGCGCGACGGATGTGGAACTTTTTATGACCGGGCCAATGCTCCATAAGCTGGAGGGAGA
AGCAAATGTAACACCGGTCAAGGTTGACTTTGATCGAACAACAGGAAGCTTCTACGGCGAATTTATCTGGGAGAACTCAT
GGGAAGGCCAATGGCACAAGCGCCACTATGGAGCCTGTTCCGAGCCGGTCTGCTGGAGTCAGATCGGTTACGCCTGCGGC
TACTCGACGGCCTTCATGGGACGACCGATTTTGTACAAGGAAGTGGAATGCATAGGGATGGGAGATACTCATTGCCGCAT
CATCGGCAAGCCGATCGATGAATGGGATGACGCACGTGACTATGCGCGTCTTTTCAGTCGGGAGTCCATTGCCGAGCAGC
TCATTGACCTGCAGACCCAGGTGATACAGCTCCGCTCCGCCATAAACAAAAAGGAAAAGCTTCCCGAAGACGTTGTCGGC
AATTCAAAGGTCTTCCGGGCGGCCTATGATTTGCTCCAGCAGGCGGCCAAAAGTCAGATTACGGTGCTGCTCCTGGGGGA
GACCGGCGTTGGCAAAGAGGTGTTCGCCCGGACCCTCCACGCCAGTGGTGCCCGCAACAAAGAACCCTTCATCGCCATAA
ACTGTGCGGCAATTCCCCATGATCTGGTGGAATCCGAGTTGTTCGGCGTTGAAAAGGGTGCCTATACCGGGGCAGTAACG
GCCCGTGCCGGGCGCTTCGAACGGGCAAACGGCGGTACGTTGTTTCTCGACGAGGTGGGTGATTTGCCCCTTTCGGCGCA
GGCCAAGCTCTTGCGTGTCTTGCAGGAAGGTGAGCTCGAACGCGTCGGCGACCATAAAACCCGTAAGGTCAATGTGCGCT
TGGTGGCAGCGACCAACATCGATCTGAAGCAACTGGTCCAGGAGGGGAGGTTCCGGTCGGACCTCTATTATCGGCTCAAT
GCCTTCCAGATCAACATCCCCCCTCTCAGGGAGCGCAAGGAGGATATTTCACTGCTTGCCCGACGTTTCCTGGAAAAATA
TTCCGCGATCCACGGCAAGAAACTGCGTGGCTTCACCGATAAGGCCAAACGCTCGCTCCTGGCATATCCCTGGCCGGGCA
ACATTCGCGAACTGCAGAACATGATTGAGCGTGGCGTCATTCTTGCCCCAAGCGGCACCCGCATCGAGCTGGAGCATATG
TTTTCGGCCAGCGGCGACGAGCATGCCCATGAACTCGGGCTCGACGGCAACGGCGATCTTAACGGCAGGCGCGGGAAAGG
CGCTGAAGAAATTTGCGAGATGGTTTTCAGTGGCGCCATGACGCTGGATCAGCTGGAGGCCATGTTGATTGAAACCGCTG
TGAGCAAGACCGGCGGCAATCTTGCCTCGGCTGCCAGGAAACTCGGCCTGACCCGGCGTCAGTTTGCCTACCGATTGAAC
CGGCTGCATGAAGGAGAGGTGGCGGTAATAGGGGGCAATGCTTGA

Upstream 100 bases:

>100_bases
CATCTGACAATCTATCAAATTAGGCAATGATAATAAAATATCGTTATGAAATGACGGTTCAAAAAGTGATTCTGGTGCCA
ATTTGCGGTGAGGTGGGAAA

Downstream 100 bases:

>100_bases
TCCATGGGGCAGGCGGGACAAACCTGCCCGCAATCGGAACGAACTGTCTTATCAATTGATTAATCGATAAAACATGGTTA
CACGATCATTTGATTATATG

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MTKQRRSDKPGCTLTDGDLLGRVHFCRESGNIWLHEHRMLLVHAEAQATLRRELIDTLGIERVQGLLTRMGYAAGMHDAE
LVCTRVEGATDVELFMTGPMLHKLEGEANVTPVKVDFDRTTGSFYGEFIWENSWEGQWHKRHYGACSEPVCWSQIGYACG
YSTAFMGRPILYKEVECIGMGDTHCRIIGKPIDEWDDARDYARLFSRESIAEQLIDLQTQVIQLRSAINKKEKLPEDVVG
NSKVFRAAYDLLQQAAKSQITVLLLGETGVGKEVFARTLHASGARNKEPFIAINCAAIPHDLVESELFGVEKGAYTGAVT
ARAGRFERANGGTLFLDEVGDLPLSAQAKLLRVLQEGELERVGDHKTRKVNVRLVAATNIDLKQLVQEGRFRSDLYYRLN
AFQINIPPLRERKEDISLLARRFLEKYSAIHGKKLRGFTDKAKRSLLAYPWPGNIRELQNMIERGVILAPSGTRIELEHM
FSASGDEHAHELGLDGNGDLNGRRGKGAEEICEMVFSGAMTLDQLEAMLIETAVSKTGGNLASAARKLGLTRRQFAYRLN
RLHEGEVAVIGGNA

Sequences:

>Translated_574_residues
MTKQRRSDKPGCTLTDGDLLGRVHFCRESGNIWLHEHRMLLVHAEAQATLRRELIDTLGIERVQGLLTRMGYAAGMHDAE
LVCTRVEGATDVELFMTGPMLHKLEGEANVTPVKVDFDRTTGSFYGEFIWENSWEGQWHKRHYGACSEPVCWSQIGYACG
YSTAFMGRPILYKEVECIGMGDTHCRIIGKPIDEWDDARDYARLFSRESIAEQLIDLQTQVIQLRSAINKKEKLPEDVVG
NSKVFRAAYDLLQQAAKSQITVLLLGETGVGKEVFARTLHASGARNKEPFIAINCAAIPHDLVESELFGVEKGAYTGAVT
ARAGRFERANGGTLFLDEVGDLPLSAQAKLLRVLQEGELERVGDHKTRKVNVRLVAATNIDLKQLVQEGRFRSDLYYRLN
AFQINIPPLRERKEDISLLARRFLEKYSAIHGKKLRGFTDKAKRSLLAYPWPGNIRELQNMIERGVILAPSGTRIELEHM
FSASGDEHAHELGLDGNGDLNGRRGKGAEEICEMVFSGAMTLDQLEAMLIETAVSKTGGNLASAARKLGLTRRQFAYRLN
RLHEGEVAVIGGNA
>Mature_573_residues
TKQRRSDKPGCTLTDGDLLGRVHFCRESGNIWLHEHRMLLVHAEAQATLRRELIDTLGIERVQGLLTRMGYAAGMHDAEL
VCTRVEGATDVELFMTGPMLHKLEGEANVTPVKVDFDRTTGSFYGEFIWENSWEGQWHKRHYGACSEPVCWSQIGYACGY
STAFMGRPILYKEVECIGMGDTHCRIIGKPIDEWDDARDYARLFSRESIAEQLIDLQTQVIQLRSAINKKEKLPEDVVGN
SKVFRAAYDLLQQAAKSQITVLLLGETGVGKEVFARTLHASGARNKEPFIAINCAAIPHDLVESELFGVEKGAYTGAVTA
RAGRFERANGGTLFLDEVGDLPLSAQAKLLRVLQEGELERVGDHKTRKVNVRLVAATNIDLKQLVQEGRFRSDLYYRLNA
FQINIPPLRERKEDISLLARRFLEKYSAIHGKKLRGFTDKAKRSLLAYPWPGNIRELQNMIERGVILAPSGTRIELEHMF
SASGDEHAHELGLDGNGDLNGRRGKGAEEICEMVFSGAMTLDQLEAMLIETAVSKTGGNLASAARKLGLTRRQFAYRLNR
LHEGEVAVIGGNA

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=236, Percent_Identity=55.0847457627119, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1788550, Length=318, Percent_Identity=46.2264150943396, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1790437, Length=324, Percent_Identity=43.5185185185185, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790299, Length=335, Percent_Identity=41.1940298507463, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI1789087, Length=260, Percent_Identity=48.0769230769231, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1788905, Length=343, Percent_Identity=40.5247813411079, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789233, Length=242, Percent_Identity=47.1074380165289, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI87081872, Length=327, Percent_Identity=40.6727828746177, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082152, Length=218, Percent_Identity=49.0825688073394, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786524, Length=241, Percent_Identity=46.0580912863071, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1787583, Length=256, Percent_Identity=39.0625, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789828, Length=233, Percent_Identity=40.343347639485, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=31.5789473684211, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 64023; Mature: 63892

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQRRSDKPGCTLTDGDLLGRVHFCRESGNIWLHEHRMLLVHAEAQATLRRELIDTLGI
CCCCCCCCCCCCEEECCHHHHHHHEEECCCCEEEEECEEEEEECHHHHHHHHHHHHHHCH
ERVQGLLTRMGYAAGMHDAELVCTRVEGATDVELFMTGPMLHKLEGEANVTPVKVDFDRT
HHHHHHHHHHHHHCCCCCHHEEEEECCCCCCEEEEEECCHHHHCCCCCCCCEEEEEECCC
TGSFYGEFIWENSWEGQWHKRHYGACSEPVCWSQIGYACGYSTAFMGRPILYKEVECIGM
CCCHHHHEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHHCCCCCHHCCEEEEEC
GDTHCRIIGKPIDEWDDARDYARLFSRESIAEQLIDLQTQVIQLRSAINKKEKLPEDVVG
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
NSKVFRAAYDLLQQAAKSQITVLLLGETGVGKEVFARTLHASGARNKEPFIAINCAAIPH
CHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCH
DLVESELFGVEKGAYTGAVTARAGRFERANGGTLFLDEVGDLPLSAQAKLLRVLQEGELE
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
RVGDHKTRKVNVRLVAATNIDLKQLVQEGRFRSDLYYRLNAFQINIPPLRERKEDISLLA
HCCCCCCEEEEEEEEEECCCCHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHH
RRFLEKYSAIHGKKLRGFTDKAKRSLLAYPWPGNIRELQNMIERGVILAPSGTRIELEHM
HHHHHHHHHHCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHHCCEEECCCCCEEEEHHH
FSASGDEHAHELGLDGNGDLNGRRGKGAEEICEMVFSGAMTLDQLEAMLIETAVSKTGGN
HCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
LASAARKLGLTRRQFAYRLNRLHEGEVAVIGGNA
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure 
TKQRRSDKPGCTLTDGDLLGRVHFCRESGNIWLHEHRMLLVHAEAQATLRRELIDTLGI
CCCCCCCCCCCEEECCHHHHHHHEEECCCCEEEEECEEEEEECHHHHHHHHHHHHHHCH
ERVQGLLTRMGYAAGMHDAELVCTRVEGATDVELFMTGPMLHKLEGEANVTPVKVDFDRT
HHHHHHHHHHHHHCCCCCHHEEEEECCCCCCEEEEEECCHHHHCCCCCCCCEEEEEECCC
TGSFYGEFIWENSWEGQWHKRHYGACSEPVCWSQIGYACGYSTAFMGRPILYKEVECIGM
CCCHHHHEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHHCCCCCHHCCEEEEEC
GDTHCRIIGKPIDEWDDARDYARLFSRESIAEQLIDLQTQVIQLRSAINKKEKLPEDVVG
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
NSKVFRAAYDLLQQAAKSQITVLLLGETGVGKEVFARTLHASGARNKEPFIAINCAAIPH
CHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCH
DLVESELFGVEKGAYTGAVTARAGRFERANGGTLFLDEVGDLPLSAQAKLLRVLQEGELE
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
RVGDHKTRKVNVRLVAATNIDLKQLVQEGRFRSDLYYRLNAFQINIPPLRERKEDISLLA
HCCCCCCEEEEEEEEEECCCCHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHH
RRFLEKYSAIHGKKLRGFTDKAKRSLLAYPWPGNIRELQNMIERGVILAPSGTRIELEHM
HHHHHHHHHHCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHHCCEEECCCCCEEEEHHH
FSASGDEHAHELGLDGNGDLNGRRGKGAEEICEMVFSGAMTLDQLEAMLIETAVSKTGGN
HCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
LASAARKLGLTRRQFAYRLNRLHEGEVAVIGGNA
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]