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The map label for this gene is nuoE [H]

Identifier: 78223288

GI number: 78223288

Start: 2341148

End: 2341600

Strand: Reverse

Name: nuoE [H]

Synonym: Gmet_2081

Alternate gene names: 78223288

Gene position: 2341600-2341148 (Counterclockwise)

Preceding gene: 78223289

Following gene: 78223287

Centisome position: 58.58

GC content: 57.4

Gene sequence:

>453_bases
ATGGATATCTCTAGAATAGACCAGATTATTGACAAGCATGACGGTGAAGCCAGTTCGCTCATACAGATCCTGCTGGATAT
CCAGAGCGAGCACAATTGGTTGCCCAAGGAGGCGCTGAAAAGAGTCTGTGAGAGACTGCAGGTGCCCATGAGCCGCATCA
CGCACATTGCCACGTTTTACAAGGCCTTCAGCCTCGTTCCGAAGGGGCGTCATCAGGTTCACGTCTGCATGGGGACTGCC
TGCCACGTCCGGGGCGCCCAGCGGGTCCTCGACACGGTGCAGGAGGTGACCGGCGTCAAGTCCGGCGAGACGGACTCCGA
CCTGAAGTTCAGCGTCGAAACCGTTAACTGTCTCGGCTGCTGCGCCCTCGGGCCGGTTATGGAAGTGGACGGCAAACACC
ATGGCAACATTGCCCCGTCCCAGATTGCATCCGTGCTGAATAACTGCGAGTAA

Upstream 100 bases:

>100_bases
AGCGTACCCGTTGGTACGTTGAGCTTTCGAGCAAGCGGCAACAACGCAGACCGGACCCGCAATAGTTTTGCAAGTGCCTC
GGAGGAAAAGGAAGGCGACC

Downstream 100 bases:

>100_bases
GGGTGATTTATGACAAGGTTAAGCTCCCCTGAAAAATTGGAATGTGCCAGGAAGGACATCGTCTCCCGCATTGACCCGAC
CAAGCCGTGCATCTCGGTAT

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MDISRIDQIIDKHDGEASSLIQILLDIQSEHNWLPKEALKRVCERLQVPMSRITHIATFYKAFSLVPKGRHQVHVCMGTA
CHVRGAQRVLDTVQEVTGVKSGETDSDLKFSVETVNCLGCCALGPVMEVDGKHHGNIAPSQIASVLNNCE

Sequences:

>Translated_150_residues
MDISRIDQIIDKHDGEASSLIQILLDIQSEHNWLPKEALKRVCERLQVPMSRITHIATFYKAFSLVPKGRHQVHVCMGTA
CHVRGAQRVLDTVQEVTGVKSGETDSDLKFSVETVNCLGCCALGPVMEVDGKHHGNIAPSQIASVLNNCE
>Mature_150_residues
MDISRIDQIIDKHDGEASSLIQILLDIQSEHNWLPKEALKRVCERLQVPMSRITHIATFYKAFSLVPKGRHQVHVCMGTA
CHVRGAQRVLDTVQEVTGVKSGETDSDLKFSVETVNCLGCCALGPVMEVDGKHHGNIAPSQIASVLNNCE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=148, Percent_Identity=30.4054054054054, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788621, Length=133, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561328, Length=148, Percent_Identity=33.1081081081081, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859877, Length=146, Percent_Identity=31.5068493150685, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355353, Length=126, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16516; Mature: 16516

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISRIDQIIDKHDGEASSLIQILLDIQSEHNWLPKEALKRVCERLQVPMSRITHIATFY
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
KAFSLVPKGRHQVHVCMGTACHVRGAQRVLDTVQEVTGVKSGETDSDLKFSVETVNCLGC
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHH
CALGPVMEVDGKHHGNIAPSQIASVLNNCE
HHHCCHHHCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDISRIDQIIDKHDGEASSLIQILLDIQSEHNWLPKEALKRVCERLQVPMSRITHIATFY
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
KAFSLVPKGRHQVHVCMGTACHVRGAQRVLDTVQEVTGVKSGETDSDLKFSVETVNCLGC
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHH
CALGPVMEVDGKHHGNIAPSQIASVLNNCE
HHHCCHHHCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA