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The map label for this gene is fmt [H]

Identifier: 78223232

GI number: 78223232

Start: 2265888

End: 2266700

Strand: Reverse

Name: fmt [H]

Synonym: Gmet_2025

Alternate gene names: 78223232

Gene position: 2266700-2265888 (Counterclockwise)

Preceding gene: 78223233

Following gene: 78223231

Centisome position: 56.7

GC content: 59.9

Gene sequence:

>813_bases
ATGCCCATGAGCGACACGAAAAGCAAAAAACTGAACGTCCTGTTCATCACCCAGGACGACCCTTTCTACGTCAGGCTCTT
CTTCGAGGAGTTTTTCAAGTCTTTCAACGATCTTGCGTCCATCAAGGGGGTCGTAATCGCCGCTGCCATGGGGAAGAAGG
GCCCTGTGCAGCTGGCCCGGCAGATGTACGACTTCTACGGCCCCCTGGATTTCGTTCGGGTCGGCACCCGCTATGCGTCT
TACAAGGTGAAGGCCAGGATACCGGCCCTGGCCGGGGGGAACTTCTACAGCGTTGGCCAACTCTGTGCCCACCATGGAAT
GCCGGTCTTCAGTACCAACCGGGTCAACTCCCCTGAATTCCTCGCGTCGCTCCGGGAGATGGACCTGGACCTCATCGCCT
CCGTTGCCGCCCCGGTCATCTTCAAGAAGGAACTGGTGGAACTGCCTCGGCTTGGCTGCATCAACATCCATAACGGCGCG
CTTCCCCGCTACCGGGGCATGCTCCCCAATTTCTGGCAGATGTACCACAACGAGCGGCAGGTGGGGATCACGATCCACGA
GATGAACGAGAAGCTTGACGACGGGCGTATCCTCCGCCAGGAGATGGTCGATATCCTCCCCGGCGAGACCCTCGACTCCC
TCATCCGGCGGACCAAGATCCTGGGCGCCCACGTCATGGCCCGGGCCATCGCCTCGCTGCGGGACGGCACCGCCACGTAC
CGCGAGAATCCTGCGTCCGAGGGGTCCTATTTTTCCTTTCCGACCAAAGACCACGTGCGGGAATTCAAACAGAACGGCAA
GAGGCTGATCTGA

Upstream 100 bases:

>100_bases
CTCTTCAAACTCATCAAGATGGTTGATAAAGGCGGCAAACAGCTTCCCGATCCTCCCAAAAAGGGCTTCTGGAACTGGAT
GACCAACTGACGGAATAACG

Downstream 100 bases:

>100_bases
GCGCGGCCATGAAGGATCATCACCAATGAGCCAGGGAATTTTCGGGATAATCGATTTCAGGAACGCCATTGCCGACAGGG
ATGTGCTGGGTAATGCCATG

Product: Formyl transferase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MPMSDTKSKKLNVLFITQDDPFYVRLFFEEFFKSFNDLASIKGVVIAAAMGKKGPVQLARQMYDFYGPLDFVRVGTRYAS
YKVKARIPALAGGNFYSVGQLCAHHGMPVFSTNRVNSPEFLASLREMDLDLIASVAAPVIFKKELVELPRLGCINIHNGA
LPRYRGMLPNFWQMYHNERQVGITIHEMNEKLDDGRILRQEMVDILPGETLDSLIRRTKILGAHVMARAIASLRDGTATY
RENPASEGSYFSFPTKDHVREFKQNGKRLI

Sequences:

>Translated_270_residues
MPMSDTKSKKLNVLFITQDDPFYVRLFFEEFFKSFNDLASIKGVVIAAAMGKKGPVQLARQMYDFYGPLDFVRVGTRYAS
YKVKARIPALAGGNFYSVGQLCAHHGMPVFSTNRVNSPEFLASLREMDLDLIASVAAPVIFKKELVELPRLGCINIHNGA
LPRYRGMLPNFWQMYHNERQVGITIHEMNEKLDDGRILRQEMVDILPGETLDSLIRRTKILGAHVMARAIASLRDGTATY
RENPASEGSYFSFPTKDHVREFKQNGKRLI
>Mature_269_residues
PMSDTKSKKLNVLFITQDDPFYVRLFFEEFFKSFNDLASIKGVVIAAAMGKKGPVQLARQMYDFYGPLDFVRVGTRYASY
KVKARIPALAGGNFYSVGQLCAHHGMPVFSTNRVNSPEFLASLREMDLDLIASVAAPVIFKKELVELPRLGCINIHNGAL
PRYRGMLPNFWQMYHNERQVGITIHEMNEKLDDGRILRQEMVDILPGETLDSLIRRTKILGAHVMARAIASLRDGTATYR
ENPASEGSYFSFPTKDHVREFKQNGKRLI

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Escherichia coli, GI1789683, Length=160, Percent_Identity=30, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788589, Length=164, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 30613; Mature: 30482

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSDTKSKKLNVLFITQDDPFYVRLFFEEFFKSFNDLASIKGVVIAAAMGKKGPVQLAR
CCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMYDFYGPLDFVRVGTRYASYKVKARIPALAGGNFYSVGQLCAHHGMPVFSTNRVNSPEF
HHHHHHCCHHHHHHCCHHHHEEEEEECCEEECCCHHHHHHHHHHCCCCEEECCCCCCHHH
LASLREMDLDLIASVAAPVIFKKELVELPRLGCINIHNGALPRYRGMLPNFWQMYHNERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCHHHHHHHCCCCE
VGITIHEMNEKLDDGRILRQEMVDILPGETLDSLIRRTKILGAHVMARAIASLRDGTATY
EEEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RENPASEGSYFSFPTKDHVREFKQNGKRLI
CCCCCCCCCEECCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PMSDTKSKKLNVLFITQDDPFYVRLFFEEFFKSFNDLASIKGVVIAAAMGKKGPVQLAR
CCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QMYDFYGPLDFVRVGTRYASYKVKARIPALAGGNFYSVGQLCAHHGMPVFSTNRVNSPEF
HHHHHHCCHHHHHHCCHHHHEEEEEECCEEECCCHHHHHHHHHHCCCCEEECCCCCCHHH
LASLREMDLDLIASVAAPVIFKKELVELPRLGCINIHNGALPRYRGMLPNFWQMYHNERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCHHHHHHHCCCCE
VGITIHEMNEKLDDGRILRQEMVDILPGETLDSLIRRTKILGAHVMARAIASLRDGTATY
EEEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RENPASEGSYFSFPTKDHVREFKQNGKRLI
CCCCCCCCCEECCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA