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The map label for this gene is pgsA [H]

Identifier: 78223159

GI number: 78223159

Start: 2179075

End: 2179668

Strand: Reverse

Name: pgsA [H]

Synonym: Gmet_1952

Alternate gene names: 78223159

Gene position: 2179668-2179075 (Counterclockwise)

Preceding gene: 78223160

Following gene: 78223157

Centisome position: 54.53

GC content: 55.22

Gene sequence:

>594_bases
ATGCCTGACACTAACGCCAAGACCATCTGGAATATCCCGAACATTCTCACTCTCCTGCGAATCGCTCTGATACCCGTTTT
GGCGGTGCTTCTTCTGTCACCGTCCCGGGAAGCGGGATTCTGGGCCGCTGCCGTGTTCGCCGTCGCCTCAACCACCGACT
GGCTTGACGGCTATCTAGCCCGCAGGATGGGTATCGTTACTGTCTTCGGCAAGTTCCTTGACCCCATTGCAGACAAGCTC
ATGGTGATGGCGGCACTCATCATGATCCTCCCCTACAATCGGGTTCCTGCCTGGATGGTTCTTGTAATCCTCGGCCGCGA
GATCATCATTACGGGGCTGCGGGGGATCGCCTCCAGCGAGGGGATTGTCATATCCGCCAGCGATCTGGGAAAGTTCAAGA
CCATCTTCCAGATGGTGGCTATCATCGGGCTGCTTCTCCACTATGACTACCACTGGTTTTTCGGGGTCGACAACCCCTAT
CTCATCGTCAACATGCACAATGCAGGGATGTTCTATCTCTGGATCGCCACAATTATGACTGTCTGGTCCGGAGCCGACTA
CCTTGCCAAGTTCATGAGGGTAATAGCCCGCTGA

Upstream 100 bases:

>100_bases
GTATAACGGCATTCCCCCTTATCAGGAAACGCGCACCTATGTCGACAGGGTGCTTACTTACAGAAAATCCTACCAGACCA
CCAATTGAGAATCAGCGTAC

Downstream 100 bases:

>100_bases
CCATTTCCTAGGTCTTATTTCTCTTCCAGTGCCATAGGCTCACAGACATTGTCCCCTGAATTTGCTTTGGACCCGCAGAT
AAAGCAGACGACGGTCGGGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MPDTNAKTIWNIPNILTLLRIALIPVLAVLLLSPSREAGFWAAAVFAVASTTDWLDGYLARRMGIVTVFGKFLDPIADKL
MVMAALIMILPYNRVPAWMVLVILGREIIITGLRGIASSEGIVISASDLGKFKTIFQMVAIIGLLLHYDYHWFFGVDNPY
LIVNMHNAGMFYLWIATIMTVWSGADYLAKFMRVIAR

Sequences:

>Translated_197_residues
MPDTNAKTIWNIPNILTLLRIALIPVLAVLLLSPSREAGFWAAAVFAVASTTDWLDGYLARRMGIVTVFGKFLDPIADKL
MVMAALIMILPYNRVPAWMVLVILGREIIITGLRGIASSEGIVISASDLGKFKTIFQMVAIIGLLLHYDYHWFFGVDNPY
LIVNMHNAGMFYLWIATIMTVWSGADYLAKFMRVIAR
>Mature_196_residues
PDTNAKTIWNIPNILTLLRIALIPVLAVLLLSPSREAGFWAAAVFAVASTTDWLDGYLARRMGIVTVFGKFLDPIADKLM
VMAALIMILPYNRVPAWMVLVILGREIIITGLRGIASSEGIVISASDLGKFKTIFQMVAIIGLLLHYDYHWFFGVDNPYL
IVNMHNAGMFYLWIATIMTVWSGADYLAKFMRVIAR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=37.8378378378378, Blast_Score=104, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320059, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22010; Mature: 21879

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTNAKTIWNIPNILTLLRIALIPVLAVLLLSPSREAGFWAAAVFAVASTTDWLDGYLA
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMGIVTVFGKFLDPIADKLMVMAALIMILPYNRVPAWMVLVILGREIIITGLRGIASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GIVISASDLGKFKTIFQMVAIIGLLLHYDYHWFFGVDNPYLIVNMHNAGMFYLWIATIMT
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHH
VWSGADYLAKFMRVIAR
HHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PDTNAKTIWNIPNILTLLRIALIPVLAVLLLSPSREAGFWAAAVFAVASTTDWLDGYLA
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMGIVTVFGKFLDPIADKLMVMAALIMILPYNRVPAWMVLVILGREIIITGLRGIASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GIVISASDLGKFKTIFQMVAIIGLLLHYDYHWFFGVDNPYLIVNMHNAGMFYLWIATIMT
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHH
VWSGADYLAKFMRVIAR
HHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]