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The map label for this gene is purQ [H]

Identifier: 78223147

GI number: 78223147

Start: 2164828

End: 2165655

Strand: Reverse

Name: purQ [H]

Synonym: Gmet_1940

Alternate gene names: 78223147

Gene position: 2165655-2164828 (Counterclockwise)

Preceding gene: 78223148

Following gene: 78223146

Centisome position: 54.18

GC content: 60.51

Gene sequence:

>828_bases
ATGGCAAAAGCACGTGCACTAGTCATAACCGGTAACGGTACCAACTGCGAGACGGAGGCGGCCCACGCCTGCCGGCTCGG
CGGCTTCGACGAGGCGGTCATTGCCCACATCTCCGACCTCCTGTCCGGGGATATTCGGTTGGACGATTTCCACTTCATCA
ACCTCACCGGCGGTTTCCTGGACGGCGACGATCTGGGGAGCGCCAAGGCCCAGGCCAACCGTTTCCGGTACGCCAAGGTG
AACGATCTGGCCGAACATCTCATCGATCAGTTAACCCGATTCATCGAGGCGGGGAAGCTGATCCTCGGGGTCTGCAACGG
CTTTCAGCTCATGGTGAAGATGGGGCTTCTGCCGGCCCTAGACGGCGCCTATCTCAAACAAACCGCGACGCTGACTTTCA
ACGACTGTGGCCGCTTCCAGGACCGCTGGGTCTATCTCAAGGTGGATCCAACATCTCCCTCGGTCTACACGAAGGGGGTA
GCAAAGGGGCTGTACCTGCCGATGCGTCACGGTGAAGGGAAGTTTGTCGTCGACGGCCCGGCCACCCTTGCCGCCATCGA
GGAAAAACATCTGGCTGTTTTCAAATATTCCGACGCCGCCTACGACGCCCCCACCATGGAATTCCCCTTGAACCCCAACG
GGTCGGTGAACGCCATTGCGGCCCTTTGCGACGGGACCGGCCGCCTCATGGGGATGATGCCCCACCCCGAGGCCTTCGTC
CACCGGACCCAGCATCCCCGCTGGACCCGCGAGGAGCTTCCCGAAGAAGGGGACGGCCTTGTCCTCTTCAAGAACGCTGC
CGAGTATGTCAAACTAAACTTGCTGTAA

Upstream 100 bases:

>100_bases
GGGGCGGTGCGTATCACGGGCCTTTCCGGCCAGGCGGTGGTCGAAGCAAGCATCGACGAACTGAAAGAAGCGTGGCAGAG
CCCGCTGAGGGAGCTGTAAC

Downstream 100 bases:

>100_bases
GACCGCTGAAACCAGGCGGCTGCCACCGTGCAGCCGCTTATTTCGTGCATGGAGACGGAATGAAGCTTTACAGACCTACG
GAAGAGTGCGGCATTTTTGG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAKARALVITGNGTNCETEAAHACRLGGFDEAVIAHISDLLSGDIRLDDFHFINLTGGFLDGDDLGSAKAQANRFRYAKV
NDLAEHLIDQLTRFIEAGKLILGVCNGFQLMVKMGLLPALDGAYLKQTATLTFNDCGRFQDRWVYLKVDPTSPSVYTKGV
AKGLYLPMRHGEGKFVVDGPATLAAIEEKHLAVFKYSDAAYDAPTMEFPLNPNGSVNAIAALCDGTGRLMGMMPHPEAFV
HRTQHPRWTREELPEEGDGLVLFKNAAEYVKLNLL

Sequences:

>Translated_275_residues
MAKARALVITGNGTNCETEAAHACRLGGFDEAVIAHISDLLSGDIRLDDFHFINLTGGFLDGDDLGSAKAQANRFRYAKV
NDLAEHLIDQLTRFIEAGKLILGVCNGFQLMVKMGLLPALDGAYLKQTATLTFNDCGRFQDRWVYLKVDPTSPSVYTKGV
AKGLYLPMRHGEGKFVVDGPATLAAIEEKHLAVFKYSDAAYDAPTMEFPLNPNGSVNAIAALCDGTGRLMGMMPHPEAFV
HRTQHPRWTREELPEEGDGLVLFKNAAEYVKLNLL
>Mature_274_residues
AKARALVITGNGTNCETEAAHACRLGGFDEAVIAHISDLLSGDIRLDDFHFINLTGGFLDGDDLGSAKAQANRFRYAKVN
DLAEHLIDQLTRFIEAGKLILGVCNGFQLMVKMGLLPALDGAYLKQTATLTFNDCGRFQDRWVYLKVDPTSPSVYTKGVA
KGLYLPMRHGEGKFVVDGPATLAAIEEKHLAVFKYSDAAYDAPTMEFPLNPNGSVNAIAALCDGTGRLMGMMPHPEAFVH
RTQHPRWTREELPEEGDGLVLFKNAAEYVKLNLL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=283, Percent_Identity=33.9222614840989, Blast_Score=117, Evalue=8e-27,
Organism=Escherichia coli, GI48994899, Length=267, Percent_Identity=36.3295880149813, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553022, Length=240, Percent_Identity=28.75, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321498, Length=283, Percent_Identity=29.6819787985866, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24582111, Length=285, Percent_Identity=31.9298245614035, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24582109, Length=285, Percent_Identity=31.9298245614035, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17137292, Length=285, Percent_Identity=31.9298245614035, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 30073; Mature: 29942

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKARALVITGNGTNCETEAAHACRLGGFDEAVIAHISDLLSGDIRLDDFHFINLTGGFL
CCCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCEEEEEEECCCC
DGDDLGSAKAQANRFRYAKVNDLAEHLIDQLTRFIEAGKLILGVCNGFQLMVKMGLLPAL
CCCCCCCCHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCEEEEHHCHHHHHHHHCCCCCC
DGAYLKQTATLTFNDCGRFQDRWVYLKVDPTSPSVYTKGVAKGLYLPMRHGEGKFVVDGP
CCHHHHEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEEEEECCCCCEEEECC
ATLAAIEEKHLAVFKYSDAAYDAPTMEFPLNPNGSVNAIAALCDGTGRLMGMMPHPEAFV
CEEEECCCCEEEEEEECCCCCCCCCEEECCCCCCCCEEEEEEECCCCCEEECCCCCHHHH
HRTQHPRWTREELPEEGDGLVLFKNAAEYVKLNLL
CCCCCCCCCHHHCCCCCCCEEEECCCCEEEEEECC
>Mature Secondary Structure 
AKARALVITGNGTNCETEAAHACRLGGFDEAVIAHISDLLSGDIRLDDFHFINLTGGFL
CCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCEEEEEEECCCC
DGDDLGSAKAQANRFRYAKVNDLAEHLIDQLTRFIEAGKLILGVCNGFQLMVKMGLLPAL
CCCCCCCCHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCEEEEHHCHHHHHHHHCCCCCC
DGAYLKQTATLTFNDCGRFQDRWVYLKVDPTSPSVYTKGVAKGLYLPMRHGEGKFVVDGP
CCHHHHEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEEEEECCCCCEEEECC
ATLAAIEEKHLAVFKYSDAAYDAPTMEFPLNPNGSVNAIAALCDGTGRLMGMMPHPEAFV
CEEEECCCCEEEEEEECCCCCCCCCEEECCCCCCCCEEEEEEECCCCCEEECCCCCHHHH
HRTQHPRWTREELPEEGDGLVLFKNAAEYVKLNLL
CCCCCCCCCHHHCCCCCCCEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA