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The map label for this gene is glmM

Identifier: 78223093

GI number: 78223093

Start: 2100595

End: 2101950

Strand: Reverse

Name: glmM

Synonym: Gmet_1886

Alternate gene names: 78223093

Gene position: 2101950-2100595 (Counterclockwise)

Preceding gene: 78223094

Following gene: 78223092

Centisome position: 52.58

GC content: 58.41

Gene sequence:

>1356_bases
ATGAAGAAGCTTTTCGGTACTGATGGCGTTCGCGGCGTGGCGAACGTTTATCCCATGACGACGGAAATGGCCATGCAGAT
CGGCCGTGCCGCAGCCTATCTGTTCAAGAACGGCAACCGGCGGCACCGGATCGTCATTGGCAAGGATACCCGCCTTTCCG
GTTACATGCTGGAGAACGCCCTGGTGGCCGGTATCTGTTCCATGGGAGTAGACGTACTCGTGGTAGGGCCACTGCCAACC
CCGGGCATTGCCAATATCACCTCGTCCATGCGGGCTGACGCGGGAGTGGTCATCTCGGCATCCCACAACGCTTTTCAGGA
TAACGGCATCAAGTTCTTCTCCCGGGATGGTTTCAAGCTCCCCGATGAGATGGAACTCAAGATCGAGGAGCTGATCTTTT
CCAAGAAGATCGATTCCCTGCGCCCCATTGCCACCGAGGTGGGGAAGGCCTACCGGATCGACGATGCGGTGGGGCGCTAT
GTGGTCTTTCTCAAGAACACCTTCCCCAAGGAGCTTGATCTCACGGGGATGAAGATCGTCCTCGACTGCGCCAACGGTGC
CGCCTACAAGGTGGCGCCGGCAGTCCTGGAGGAGCTTGGGGCGGAGGTCATTCCCTACGGCATCAAGCCCAACGGCACTA
ACATCAATGCCGGCTTCGGATCGCTTCACCCCGAGGTGATCAGCGAGGCAGTCAAGGAGCACCGGGCCGATCTGGGCATA
GCCCTTGACGGCGACGCCGACCGGGTCATTTTTGTGGACGAATTCGGCAACGAGGTGGACGGCGACCACATCATGGCCAT
CTGCGCCACAGATATGCTCAAACATAAGAAACTCCGCAAGAATACCCTCGTGGCAACGGTTATGAGCAATATGGGGCTCG
ACATAGCCGTGAAAAAGGCTGGCGGGAAGGTGATCAAGACGGCAGTCGGGGACCGCTACGTGGTGGAGGAGATGCTGAAG
GGAGGCTACAACCTCGGCGGCGAGCAGTCAGGGCACATGATCTTCCTTGATCACAACACCACGGGGGACGGGATGCTCTC
CGCCCTCCAGGTCCTCGCCATCATGCGTCGAAGCGGCAAGACTCTCTCCGAGCTGGCCGAGGTGATGATTCCGCTTCCCC
AGGTCCTCGTCAATGTGCGGGTTACCGAGAAAAAGGATATCATGACGATCCCCGAGGTGGCTGCACTCATCCGGGGGGTA
GAAGATAAACTGAAGGACGAGGGGCGCATCCTCATCCGCTATTCCGGCACTGAGCCGCTGTTGCGGATCATGCTGGAAGG
TCAGGACAAATACCAGATTACCGGGTGGGCCAAGGAGATTGCCGACCTGGTTGAGAAGAAGATCGGAGGGAAGTAG

Upstream 100 bases:

>100_bases
AAGCAACAATCACCCGTCTTTTTCCTGCAACGGTTGAAGTAAGGCTGATCCGTTCCAAAACAGTCCAGAAACCGTAATTT
CGCTATCCAGGAGTTGTTAT

Downstream 100 bases:

>100_bases
GTGGCAAAGCTTGGCGTAAATATTGACCACGTGGCAACAATCAGGCAGGCGAGGGGAGGAGTGGAACCCGATCCCGTGGC
TGCCGCCGCTCTGGCGGAGT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENALVAGICSMGVDVLVVGPLPT
PGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKLPDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRY
VVFLKNTFPKELDLTGMKIVLDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGI
ALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKAGGKVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGKTLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGV
EDKLKDEGRILIRYSGTEPLLRIMLEGQDKYQITGWAKEIADLVEKKIGGK

Sequences:

>Translated_451_residues
MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENALVAGICSMGVDVLVVGPLPT
PGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKLPDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRY
VVFLKNTFPKELDLTGMKIVLDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGI
ALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKAGGKVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGKTLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGV
EDKLKDEGRILIRYSGTEPLLRIMLEGQDKYQITGWAKEIADLVEKKIGGK
>Mature_451_residues
MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENALVAGICSMGVDVLVVGPLPT
PGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKLPDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRY
VVFLKNTFPKELDLTGMKIVLDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGI
ALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKAGGKVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGKTLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGV
EDKLKDEGRILIRYSGTEPLLRIMLEGQDKYQITGWAKEIADLVEKKIGGK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=51.3452914798206, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1788361, Length=431, Percent_Identity=29.6983758700696, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17535441, Length=377, Percent_Identity=27.0557029177719, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864244, Length=407, Percent_Identity=26.2899262899263, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_GEOMG (Q39UF9)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384840.1
- ProteinModelPortal:   Q39UF9
- SMR:   Q39UF9
- STRING:   Q39UF9
- GeneID:   3739162
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1886
- NMPDR:   fig|269799.3.peg.2149
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q39UF9
- ProtClustDB:   PRK14314
- BioCyc:   GMET269799:GMET_1886-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49034; Mature: 49034

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENA
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
LVAGICSMGVDVLVVGPLPTPGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKL
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCC
PDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRYVVFLKNTFPKELDLTGMKIV
CCHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEHHHHCCEEEEEECCCCCCCCCCCEEEE
LDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGI
EEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCE
ALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKA
EECCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GGKVIKTAVGDRYVVEEMLKGGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGK
CCEEEEHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
TLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGVEDKLKDEGRILIRYSGTEPL
CHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LRIMLEGQDKYQITGWAKEIADLVEKKIGGK
HHHHCCCCCCEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENA
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
LVAGICSMGVDVLVVGPLPTPGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKL
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCC
PDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRYVVFLKNTFPKELDLTGMKIV
CCHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEHHHHCCEEEEEECCCCCCCCCCCEEEE
LDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGI
EEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCE
ALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKA
EECCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GGKVIKTAVGDRYVVEEMLKGGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGK
CCEEEEHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
TLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGVEDKLKDEGRILIRYSGTEPL
CHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LRIMLEGQDKYQITGWAKEIADLVEKKIGGK
HHHHCCCCCCEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA