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The map label for this gene is efp2 [H]

Identifier: 78223045

GI number: 78223045

Start: 2051757

End: 2052320

Strand: Direct

Name: efp2 [H]

Synonym: Gmet_1838

Alternate gene names: 78223045

Gene position: 2051757-2052320 (Clockwise)

Preceding gene: 78223044

Following gene: 78223046

Centisome position: 51.33

GC content: 55.67

Gene sequence:

>564_bases
ATGTATACTGTGGCAGATTTAAAAAAAGGACTGAAAATAACCCTCGACGGCGATCCCTATCTTGTCACCGCCTTCGAGTT
CTCCAAGCCGGGCAAGGGCCAGGCCCTGTACCGCACCAAGATGCGCAACATGATTACCGGCACTACCCTCGATCGGACCT
ACCGTTCCGGCGAGACCTTCGAACCGGCCCGTCTTGAAGAGCGCCAGATGCAGTACCTCTACAAGGAAGACAACCACTAT
ACATTCATGGACAACCAGACCTTCGAGCAGGTCCAGATGAGCGAGGACGCCGTAGGCGATGCAAAGAACTTCATGATCGA
CAACATCCAGGTCGATGTTCTGATGTTTGGGGAAAAGGCCATAGGCGTATCCCTTCCCAACTTCGTCAATCTCCGCGTCG
TCCAGACCGACCCGTGGGTCAAGGGTGACACCTCCGGCAGTGACTCCAAGCCAGCCACTGTGGAAACCGGCTACGTCCTG
CGCGTACCCCCCTTCATAGAGGAAGGCGAGATGATTGTGGTCGACACCCGCACCGGTGATTACTCCACGAGGGTCAAGGG
GTAA

Upstream 100 bases:

>100_bases
TCGTGTTGCGTCATCTTGCCATTTTTTACTTAACATCCAATCAATTATGGTGTAAAAAAGTACGTTTTTTGCAGATAACA
CCAACAAAAGGGGCTCACGT

Downstream 100 bases:

>100_bases
GCCGATGACGGCAAACTGGCGCCTTGCCCGCCGCCATGGAGCGCTCCGGGCACGGGCCCGCATCATACAGGAAATAAGAC
GCTTTTTTATTGAAGGGGGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 2 [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MYTVADLKKGLKITLDGDPYLVTAFEFSKPGKGQALYRTKMRNMITGTTLDRTYRSGETFEPARLEERQMQYLYKEDNHY
TFMDNQTFEQVQMSEDAVGDAKNFMIDNIQVDVLMFGEKAIGVSLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGEMIVVDTRTGDYSTRVKG

Sequences:

>Translated_187_residues
MYTVADLKKGLKITLDGDPYLVTAFEFSKPGKGQALYRTKMRNMITGTTLDRTYRSGETFEPARLEERQMQYLYKEDNHY
TFMDNQTFEQVQMSEDAVGDAKNFMIDNIQVDVLMFGEKAIGVSLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGEMIVVDTRTGDYSTRVKG
>Mature_187_residues
MYTVADLKKGLKITLDGDPYLVTAFEFSKPGKGQALYRTKMRNMITGTTLDRTYRSGETFEPARLEERQMQYLYKEDNHY
TFMDNQTFEQVQMSEDAVGDAKNFMIDNIQVDVLMFGEKAIGVSLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGEMIVVDTRTGDYSTRVKG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=185, Percent_Identity=45.945945945946, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=27.1739130434783, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 21197; Mature: 21197

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTVADLKKGLKITLDGDPYLVTAFEFSKPGKGQALYRTKMRNMITGTTLDRTYRSGETF
CCCHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCC
EPARLEERQMQYLYKEDNHYTFMDNQTFEQVQMSEDAVGDAKNFMIDNIQVDVLMFGEKA
CCHHHHHHHHHHEEECCCEEEEECCCCHHHHHHCCCCCCCCCCEEECCEEEEEEEECCEE
IGVSLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVLRVPPFIEEGEMIVVDTRTGD
ECEECCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
CEEECCC
>Mature Secondary Structure
MYTVADLKKGLKITLDGDPYLVTAFEFSKPGKGQALYRTKMRNMITGTTLDRTYRSGETF
CCCHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCC
EPARLEERQMQYLYKEDNHYTFMDNQTFEQVQMSEDAVGDAKNFMIDNIQVDVLMFGEKA
CCHHHHHHHHHHEEECCCEEEEECCCCHHHHHHCCCCCCCCCCEEECCEEEEEEEECCEE
IGVSLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVLRVPPFIEEGEMIVVDTRTGD
ECEECCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA