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The map label for this gene is moaA [C]

Identifier: 78223014

GI number: 78223014

Start: 2022211

End: 2023608

Strand: Direct

Name: moaA [C]

Synonym: Gmet_1807

Alternate gene names: 78223014

Gene position: 2022211-2023608 (Clockwise)

Preceding gene: 78223013

Following gene: 78223015

Centisome position: 50.59

GC content: 62.59

Gene sequence:

>1398_bases
ATGGAAACAGTGAATCTGGGTGAAACCGAAAGCATCTGCCCCGTCTGCCTGAAAAGGATAGCGGCGACACGACAAGTGCT
GGGTGACGAGGTCTTCCAGGTCAAGGAGTGCGACGAGCACGGTTCGTTCAGGACCCTTATCTGGCGCGGAAAGCCGTCAC
TGGCCGAGTGGCGGAGACCGAAGCCGCCCGTCCACCCCGAGCTCTGCTACGGGACCGTCGAGCAGGGGTGCCCGTTCGAC
TGCGGCCTCTGCAGTGCCCATGCACAGATGCCCTGTTCGGTGCTACTGGAGGTGACTGACCGGTGCAACCTGCAGTGCGC
CGTCTGTTTTGCCGATTCCGGCCGAAAGGATTCCGTGGATACCTCCCTGGACAGGATCACCTGGCTGCTAGAACGGGCCA
TGGCAGCGGCTGGGCCGTGCAATCTCCAGTTGTCCGGCGGAGAGCCCACACTGCGGGACGATCTGCCGGAGATCGTGGCA
GCGGCGCGGCGGATCGGTTTTTCCTTTATCCAGCTCAATACCAACGGCCTGCGCCTTGCCGCCGACGGGAATTATGCCGC
CCGGTTGCGGTCGGCGGGGCTTTCGGCAGTCTTTCTCCAGTTCGACGGGGTCGACGACGGCATCTACCGCACCTTGAGGG
GACGTCCGCTTCTGGAGCAGAAGCTCCGGGCCGTCAGGCATGCCGGCGAGGCCGGCCTCGGCGTGATCCTGGTCCCGACC
ATCGTGAGCGGAGTGAACAGCCATGCCGTCGGCGCCATCGTGCGGCAGGCCCTTCAATTGGCCCCAATCGTGCGGGGGAT
TCACTTCCAGCCTGTCAGCTATTTTGGCCGTTTCCCTGAGCAGGGCTGCGGCAACCGCTTCACTTTACCCGAACTGATGG
GGTGTCTCGAAGAGCAGACCGACGGACTGCTCAGGCTGGCCGATTTCTCTCCTCCCGGTGGGGAACATGCCCACTGTTCC
TTTCACGCCACATATCTCTACTCGGCCGACGGCGGGCTGCGCTCCCTCGGGGCGATGGGGGGCGATTCCTGCTGCACGAC
CGACTGTGGCAGCGGGGGAATCAGGAGGACCGTGGATACCGTGTCGCGCCGCTGGAAGCTTCCCTCAGCCGCACCATGCT
GCGGCAATCCCAGAGAATCGGAGCAGACCGATTGTTGTGAGTCGGGCAGATCAAACCCGGTCCGGGTCGAAGGGGCCATT
GATCTGGATAGCTTTCTCCGGGATGTCGCCACCAGGAGTTTAACCATCTCTGCCATGGCATTTCAAGATGCGGAAAACCT
GGATCTGGAGCGCCTCAGGGGGTGCTGCATATCGGTTGTGTCTCCCGATGGCCTGCTGGTGCCATTCTGTGCCTATAACC
TGACCAGCAGGGACGGAAGGAGCCTTTACCGCCGATGA

Upstream 100 bases:

>100_bases
GGAGAGGAAAGGGGAGGCGGCCCGTGGGGGCCTCGGCTATTTCCTCATGGTGGCCCGAAAGGCTGAAGACCCGCTTCCGT
AACAGATAAAGGATAGTGTC

Downstream 100 bases:

>100_bases
TCTGGCACGGCGGCAATCACTTCATGATTTACGTCCCATAAGATATATTATGTCAAGTACGCGAAATAAATTTTTGTCCT
GTGCCCTTGAAAGATTCAGA

Product: radical SAM family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
METVNLGETESICPVCLKRIAATRQVLGDEVFQVKECDEHGSFRTLIWRGKPSLAEWRRPKPPVHPELCYGTVEQGCPFD
CGLCSAHAQMPCSVLLEVTDRCNLQCAVCFADSGRKDSVDTSLDRITWLLERAMAAAGPCNLQLSGGEPTLRDDLPEIVA
AARRIGFSFIQLNTNGLRLAADGNYAARLRSAGLSAVFLQFDGVDDGIYRTLRGRPLLEQKLRAVRHAGEAGLGVILVPT
IVSGVNSHAVGAIVRQALQLAPIVRGIHFQPVSYFGRFPEQGCGNRFTLPELMGCLEEQTDGLLRLADFSPPGGEHAHCS
FHATYLYSADGGLRSLGAMGGDSCCTTDCGSGGIRRTVDTVSRRWKLPSAAPCCGNPRESEQTDCCESGRSNPVRVEGAI
DLDSFLRDVATRSLTISAMAFQDAENLDLERLRGCCISVVSPDGLLVPFCAYNLTSRDGRSLYRR

Sequences:

>Translated_465_residues
METVNLGETESICPVCLKRIAATRQVLGDEVFQVKECDEHGSFRTLIWRGKPSLAEWRRPKPPVHPELCYGTVEQGCPFD
CGLCSAHAQMPCSVLLEVTDRCNLQCAVCFADSGRKDSVDTSLDRITWLLERAMAAAGPCNLQLSGGEPTLRDDLPEIVA
AARRIGFSFIQLNTNGLRLAADGNYAARLRSAGLSAVFLQFDGVDDGIYRTLRGRPLLEQKLRAVRHAGEAGLGVILVPT
IVSGVNSHAVGAIVRQALQLAPIVRGIHFQPVSYFGRFPEQGCGNRFTLPELMGCLEEQTDGLLRLADFSPPGGEHAHCS
FHATYLYSADGGLRSLGAMGGDSCCTTDCGSGGIRRTVDTVSRRWKLPSAAPCCGNPRESEQTDCCESGRSNPVRVEGAI
DLDSFLRDVATRSLTISAMAFQDAENLDLERLRGCCISVVSPDGLLVPFCAYNLTSRDGRSLYRR
>Mature_465_residues
METVNLGETESICPVCLKRIAATRQVLGDEVFQVKECDEHGSFRTLIWRGKPSLAEWRRPKPPVHPELCYGTVEQGCPFD
CGLCSAHAQMPCSVLLEVTDRCNLQCAVCFADSGRKDSVDTSLDRITWLLERAMAAAGPCNLQLSGGEPTLRDDLPEIVA
AARRIGFSFIQLNTNGLRLAADGNYAARLRSAGLSAVFLQFDGVDDGIYRTLRGRPLLEQKLRAVRHAGEAGLGVILVPT
IVSGVNSHAVGAIVRQALQLAPIVRGIHFQPVSYFGRFPEQGCGNRFTLPELMGCLEEQTDGLLRLADFSPPGGEHAHCS
FHATYLYSADGGLRSLGAMGGDSCCTTDCGSGGIRRTVDTVSRRWKLPSAAPCCGNPRESEQTDCCESGRSNPVRVEGAI
DLDSFLRDVATRSLTISAMAFQDAENLDLERLRGCCISVVSPDGLLVPFCAYNLTSRDGRSLYRR

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI22027536, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI116734668, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786999, Length=187, Percent_Identity=31.5508021390374, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 50432; Mature: 50432

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVNLGETESICPVCLKRIAATRQVLGDEVFQVKECDEHGSFRTLIWRGKPSLAEWRRP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCC
KPPVHPELCYGTVEQGCPFDCGLCSAHAQMPCSVLLEVTDRCNLQCAVCFADSGRKDSVD
CCCCCHHHHHCCHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCHH
TSLDRITWLLERAMAAAGPCNLQLSGGEPTLRDDLPEIVAAARRIGFSFIQLNTNGLRLA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEE
ADGNYAARLRSAGLSAVFLQFDGVDDGIYRTLRGRPLLEQKLRAVRHAGEAGLGVILVPT
ECCCHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEHHH
IVSGVNSHAVGAIVRQALQLAPIVRGIHFQPVSYFGRFPEQGCGNRFTLPELMGCLEEQT
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
DGLLRLADFSPPGGEHAHCSFHATYLYSADGGLRSLGAMGGDSCCTTDCGSGGIRRTVDT
CCEEEEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VSRRWKLPSAAPCCGNPRESEQTDCCESGRSNPVRVEGAIDLDSFLRDVATRSLTISAMA
HHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEEEEEE
FQDAENLDLERLRGCCISVVSPDGLLVPFCAYNLTSRDGRSLYRR
ECCCCCCCHHHHCCCEEEEECCCCCEEEHHHCCCCCCCCHHHHCC
>Mature Secondary Structure
METVNLGETESICPVCLKRIAATRQVLGDEVFQVKECDEHGSFRTLIWRGKPSLAEWRRP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCC
KPPVHPELCYGTVEQGCPFDCGLCSAHAQMPCSVLLEVTDRCNLQCAVCFADSGRKDSVD
CCCCCHHHHHCCHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCHH
TSLDRITWLLERAMAAAGPCNLQLSGGEPTLRDDLPEIVAAARRIGFSFIQLNTNGLRLA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEE
ADGNYAARLRSAGLSAVFLQFDGVDDGIYRTLRGRPLLEQKLRAVRHAGEAGLGVILVPT
ECCCHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEHHH
IVSGVNSHAVGAIVRQALQLAPIVRGIHFQPVSYFGRFPEQGCGNRFTLPELMGCLEEQT
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
DGLLRLADFSPPGGEHAHCSFHATYLYSADGGLRSLGAMGGDSCCTTDCGSGGIRRTVDT
CCEEEEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VSRRWKLPSAAPCCGNPRESEQTDCCESGRSNPVRVEGAIDLDSFLRDVATRSLTISAMA
HHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEEEEEE
FQDAENLDLERLRGCCISVVSPDGLLVPFCAYNLTSRDGRSLYRR
ECCCCCCCHHHHCCCEEEEECCCCCEEEHHHCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]