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The map label for this gene is gluQ [H]

Identifier: 78222989

GI number: 78222989

Start: 1996878

End: 1997822

Strand: Direct

Name: gluQ [H]

Synonym: Gmet_1780

Alternate gene names: 78222989

Gene position: 1996878-1997822 (Clockwise)

Preceding gene: 78222987

Following gene: 78222996

Centisome position: 49.95

GC content: 64.02

Gene sequence:

>945_bases
ATGATGTCTGAACAGATACCTGATAACCGCAGCGTTGTGGGACGCTTCGCCCCGTCTCCCACTGGTCCCCTTCACCTGGG
TTCCCTGGTGGCCGCCGTGGGTAGTTATGCCATGGCGAAGCGGGAGGGAGGACTTTGGCTCCTCCGGATGGAGGATCTGG
ATACCCCTCGGGTCGTGCCGGGGATGGCGGATGACATGTTCCGCACCCTGGAAGCCCTCGGTTTTGCCTGGGACGGCGAG
GTCATGTGGCAGAGCCGCCGGTCTGATGCCTATAGTGCCGCCTTCGAGCGCCTTCTGGCGATCGGCGAGGCCTATCCCTG
TGGCTGCTCCCGGGCCGAGATCGCCCGAGCCGCCTCGGCCCCCCACGACGGCGAAGGGGAGGTGGCTTATCCCAATATCT
GCCGCAACGGCCTGCAGCCTGGGAAAGAGCCGCGCTCCTACCGCGTGAAGGTGGGGAGCGAACCTATCGTGGTACGGGAT
CTCGTCATGGGGGAGAAGCGGTATGACCTGTCACAAATTTGCGGAGATTTCGTGGTGAAGCGGGCCGACGGGCTTTTCGC
CTACCAACTGGCTGTGGTCGTGGACGACGCCGACCAGGGTGTGAACCAGGTGGTGCGGGGTGCCGACCTCCTGTCATCGA
CTCCTCGGCAGATCCTGCTCCAGAGTCTCCTCGATTACGAAACACCGGTCTACGCCCATCTTCCCCTGGTTACCGCCGCC
GGCGGGGGTAAGCTCTCCAAGCGGGACAATGCCGTGTCCCTCGCCGCCGGCCTCGATCTGGCCGTCGAAGGAGGGAGGCT
TATCCTGGCCGCGTTACGCTTCTTGGGGCAGCGTCCTCCTGAATCCCTCGCAGGATCCAACGGGAAGGAGGTTCTTGCCT
GGGGGGCGGCCAATTTTGATATCGCCCTTGTTCCCACGGCGTCCGCCCCCCTCTCGGTTCACTGA

Upstream 100 bases:

>100_bases
CCAGTATGAAAAGTCGAACCACTCCTCTCCCCATGGCAGCCTCCTGCCTCAAGTTTATCGCACCTGAAGGGATTCTCATC
AAGGGTTGGTCCGTATTCGT

Downstream 100 bases:

>100_bases
TGATTACCCTCGCAATGACCAGGAATCCCCAGCCAGCCGGTGCCGAGAATGACGAGTAGCGCAGAGGTGATCAGTAGTCC
GCCGATGGAGCCGTTGAAGA

Product: glutamyl-tRNA synthetase, class Ic

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MMSEQIPDNRSVVGRFAPSPTGPLHLGSLVAAVGSYAMAKREGGLWLLRMEDLDTPRVVPGMADDMFRTLEALGFAWDGE
VMWQSRRSDAYSAAFERLLAIGEAYPCGCSRAEIARAASAPHDGEGEVAYPNICRNGLQPGKEPRSYRVKVGSEPIVVRD
LVMGEKRYDLSQICGDFVVKRADGLFAYQLAVVVDDADQGVNQVVRGADLLSSTPRQILLQSLLDYETPVYAHLPLVTAA
GGGKLSKRDNAVSLAAGLDLAVEGGRLILAALRFLGQRPPESLAGSNGKEVLAWGAANFDIALVPTASAPLSVH

Sequences:

>Translated_314_residues
MMSEQIPDNRSVVGRFAPSPTGPLHLGSLVAAVGSYAMAKREGGLWLLRMEDLDTPRVVPGMADDMFRTLEALGFAWDGE
VMWQSRRSDAYSAAFERLLAIGEAYPCGCSRAEIARAASAPHDGEGEVAYPNICRNGLQPGKEPRSYRVKVGSEPIVVRD
LVMGEKRYDLSQICGDFVVKRADGLFAYQLAVVVDDADQGVNQVVRGADLLSSTPRQILLQSLLDYETPVYAHLPLVTAA
GGGKLSKRDNAVSLAAGLDLAVEGGRLILAALRFLGQRPPESLAGSNGKEVLAWGAANFDIALVPTASAPLSVH
>Mature_314_residues
MMSEQIPDNRSVVGRFAPSPTGPLHLGSLVAAVGSYAMAKREGGLWLLRMEDLDTPRVVPGMADDMFRTLEALGFAWDGE
VMWQSRRSDAYSAAFERLLAIGEAYPCGCSRAEIARAASAPHDGEGEVAYPNICRNGLQPGKEPRSYRVKVGSEPIVVRD
LVMGEKRYDLSQICGDFVVKRADGLFAYQLAVVVDDADQGVNQVVRGADLLSSTPRQILLQSLLDYETPVYAHLPLVTAA
GGGKLSKRDNAVSLAAGLDLAVEGGRLILAALRFLGQRPPESLAGSNGKEVLAWGAANFDIALVPTASAPLSVH

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=255, Percent_Identity=38.4313725490196, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI226510925, Length=300, Percent_Identity=40.3333333333333, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1788743, Length=269, Percent_Identity=34.5724907063197, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71993394, Length=258, Percent_Identity=32.5581395348837, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324540, Length=308, Percent_Identity=31.8181818181818, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24665321, Length=262, Percent_Identity=35.1145038167939, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 33563; Mature: 33563

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSEQIPDNRSVVGRFAPSPTGPLHLGSLVAAVGSYAMAKREGGLWLLRMEDLDTPRVVP
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
GMADDMFRTLEALGFAWDGEVMWQSRRSDAYSAAFERLLAIGEAYPCGCSRAEIARAASA
CCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
PHDGEGEVAYPNICRNGLQPGKEPRSYRVKVGSEPIVVRDLVMGEKRYDLSQICGDFVVK
CCCCCCCEECHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHCCCCCCHHHHHHHHHHH
RADGLFAYQLAVVVDDADQGVNQVVRGADLLSSTPRQILLQSLLDYETPVYAHLPLVTAA
HCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCEEEEC
GGGKLSKRDNAVSLAAGLDLAVEGGRLILAALRFLGQRPPESLAGSNGKEVLAWGAANFD
CCCCCCCCCCEEEEEECCEEEECCCHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCE
IALVPTASAPLSVH
EEEEECCCCCCCCC
>Mature Secondary Structure
MMSEQIPDNRSVVGRFAPSPTGPLHLGSLVAAVGSYAMAKREGGLWLLRMEDLDTPRVVP
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
GMADDMFRTLEALGFAWDGEVMWQSRRSDAYSAAFERLLAIGEAYPCGCSRAEIARAASA
CCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
PHDGEGEVAYPNICRNGLQPGKEPRSYRVKVGSEPIVVRDLVMGEKRYDLSQICGDFVVK
CCCCCCCEECHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHCCCCCCHHHHHHHHHHH
RADGLFAYQLAVVVDDADQGVNQVVRGADLLSSTPRQILLQSLLDYETPVYAHLPLVTAA
HCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCEEEEC
GGGKLSKRDNAVSLAAGLDLAVEGGRLILAALRFLGQRPPESLAGSNGKEVLAWGAANFD
CCCCCCCCCCEEEEEECCEEEECCCHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCE
IALVPTASAPLSVH
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA