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The map label for this gene is recG [H]

Identifier: 78222986

GI number: 78222986

Start: 1992850

End: 1995153

Strand: Direct

Name: recG [H]

Synonym: Gmet_1777

Alternate gene names: 78222986

Gene position: 1992850-1995153 (Clockwise)

Preceding gene: 78222985

Following gene: 78222987

Centisome position: 49.85

GC content: 62.37

Gene sequence:

>2304_bases
ATGCCGGTTGTTACTCTTGCCGAGAACGGTCAGCTAGCCATACCCGACGACCTTCTGAAGGATCTGGGAATCAAGCCGGG
CGATCCGGTCTTACTGGAAAAGACATCGGGCGGCATCCTCCTGTCCCGTCATGCCCCTCCTTCTCCTGGTGCGGTCCAGA
GCCGACTCCATGAGTCCATCAACCGCAAGAACCTGGAAACTCCCATTCAGTTCATAAAAGGGGTCGGTCCGAAGCTGGCG
GAGACCCTTGGCAAGAAGGGGATTGCCACGGTGGAGGATGCCCTCTATCTTCTTCCCAACCGTTACGAGGACCGCCGCCA
AGTGGTGCCCATTGCAAGGCTTTGCCCCGGAGTGACGAGTGTCTTTTCCGGCGAGGTGATTACCGCTGACGTGGTGAGCA
CCAAGGGGGGGCGTCGCTTCTTCGAAGTGGTGGTGCGGGATGCAAGCGGCACCATCTCCTTCAAATGGTTCAATTTTAAT
CCCGCCTTTCTCAAGAAGACCTGGAAGGAGGGGAGGCGGGGCATATTTACCGGACTGGTCTCTCAGTTTGGACTCCAGCG
CGAGGTGCATCATCCGGACGCCGAATGGCTGGCCGAGGGAGAAACGGTGGCATCTGTCATGGCCCGGGATCCGGTCAGTT
TCGGCCGCGTGGTGCCGGTCTACCCCCTCACCGAGGGACTCCACCAGAAGACTCTGCGGAAGGTAATGAAAGGGGTAGTG
GACCAGTATGCGTCCTGCGTGGAGAGCGCCTTGCCGCTGGAAGTGGCGGGGCGCCAGGGACTCCTGCCCCTCTCTGACGC
GCTCCGACGGGTCCACTTCCCCGACAGCGATGCCGATCCCCGGGGGCTTGAGGAAGGAAAGGATCCCGCCAATCGCACCC
TGGTTTTCGACGAGTTCTTTTTCCTTGAGCTGGGGCTGGCCATGAAAAAACGTGGCGTAACCCTCGAATCGGGAATCGCC
TTCACTGTCAGCCACACGTACACGAAGCCGCTCCTGAAACTCCTCCCCTTCTCGCTGACCGGGGCCCAGCGGCGGGTCCT
GGCCGAGATCAAGGAGGATATGATGGCTCCGCACCCCATGCACCGCCTGGTACAGGGGGATGTGGGATGCGGCAAGACCC
TCGTGGCGCTCATGGCGGCCCTGGTGGCGGTGGAGAACGGCTACCAGGTGGCGATCATGGCACCCACCGAGATCCTTGCC
GAGCAGCATTATCTGAACATTCACCGCTGGTGCGACGAACTGGGCGTTTCGGTGACGCTCGTTACCTCGTCGTTGAAGGG
GAAGGCGAAGAAGGATGCCCTGGAACGGGTAGCCGGTGGGGAGGCACAGATCGTCATCGGCACCCATGCGGTGATCCAGG
ACAAGGTGGAGTTCCATCGGCTTGGCCTCGGCATCGTGGACGAGCAGCACCGTTTCGGCGTCCTGCAGCGGGGGCTTCTG
CGGAAAAAAGGTGAGAACCCCGACATCCTTGTCATGACCGCCACCCCCATTCCCCGGACCCTTGCCATGACTGTTTTCGG
CGACCTTTCGCTGTCGGTCATCGACGAGTTGCCGCCGGGGCGGACCCCCATCGAGACGCGGATCTGTTTCGAGTCACGCC
GGAAGCAGGTCTACGGCATCATCCGCGACGAGGTGACCAAGGGGCATCAGGCGTACGTCATCTACCCCCTGGTAGAGGAG
TCGGAGAAGTCGGATCTCAAGGCCGCCACCCAGATGGCCGAGCACCTGGCCAACGACATCTTCCCGGAGTTGAGGCTCGG
CATCCTTCATGGCCGGATGAAGCCCGAGGAGAAGGAGGCGGTGATGCGCTCCTTCAAGGCGCGGGAGATCGATATCCTGG
TGGCCACCACAGTCATCGAGGTGGGGATCGACGTCCCCAATGCCACGGTGATGGTCATCGAGCATGCCGAGCGGTTCGGC
CTGTCGCAACTCCACCAGCTGCGGGGAAGGGTGGGGCGGGGGAGCGAGAAATCCCGCTGCATCCTCATGGCCGGCGAGCG
CCTTTCCGAGGACGCCGAGAAGCGGCTCCGGGTCATGGAGTCCACCACCGACGGTTTCAGGATTGCCGAGGCCGATCTGG
AGATCCGGGGCCCCGGCGATTTCCTCGGCACCCGCCAGGCGGGAATTCCCGATTTTCGCGTCGCCAACATCCTGCGGGAC
GGTCGTATCCTGGAAGAGGCCCGACAGGAGGCCTTCGCTGTGGCAGAGGTGGATCCGGAGCTGCGGTTGCCCCGGCACGA
TAAGCTCCGGACGGAGCTGGCTCGGCGTTGGGGAGGCCGGCTTGAACTGGCGGGAATCGCATAA

Upstream 100 bases:

>100_bases
CGAGGTCCTGAAAGACCTGAACGCTATCGGCCAGTAAACCTATGCCACAAGGGCGAAGGGGGAAACCTCTTCGCCCTTCG
TCTATCCGCAGCGAGGAGCC

Downstream 100 bases:

>100_bases
AAAAACAGTGCTGCACCAATTTCAGAATGGAGGAAATATGTCTGAATTCATCAACGTAACCGTAGTCCGGGAGGCAAACG
TATTCTTCAATGGCGGCGTC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MPVVTLAENGQLAIPDDLLKDLGIKPGDPVLLEKTSGGILLSRHAPPSPGAVQSRLHESINRKNLETPIQFIKGVGPKLA
ETLGKKGIATVEDALYLLPNRYEDRRQVVPIARLCPGVTSVFSGEVITADVVSTKGGRRFFEVVVRDASGTISFKWFNFN
PAFLKKTWKEGRRGIFTGLVSQFGLQREVHHPDAEWLAEGETVASVMARDPVSFGRVVPVYPLTEGLHQKTLRKVMKGVV
DQYASCVESALPLEVAGRQGLLPLSDALRRVHFPDSDADPRGLEEGKDPANRTLVFDEFFFLELGLAMKKRGVTLESGIA
FTVSHTYTKPLLKLLPFSLTGAQRRVLAEIKEDMMAPHPMHRLVQGDVGCGKTLVALMAALVAVENGYQVAIMAPTEILA
EQHYLNIHRWCDELGVSVTLVTSSLKGKAKKDALERVAGGEAQIVIGTHAVIQDKVEFHRLGLGIVDEQHRFGVLQRGLL
RKKGENPDILVMTATPIPRTLAMTVFGDLSLSVIDELPPGRTPIETRICFESRRKQVYGIIRDEVTKGHQAYVIYPLVEE
SEKSDLKAATQMAEHLANDIFPELRLGILHGRMKPEEKEAVMRSFKAREIDILVATTVIEVGIDVPNATVMVIEHAERFG
LSQLHQLRGRVGRGSEKSRCILMAGERLSEDAEKRLRVMESTTDGFRIAEADLEIRGPGDFLGTRQAGIPDFRVANILRD
GRILEEARQEAFAVAEVDPELRLPRHDKLRTELARRWGGRLELAGIA

Sequences:

>Translated_767_residues
MPVVTLAENGQLAIPDDLLKDLGIKPGDPVLLEKTSGGILLSRHAPPSPGAVQSRLHESINRKNLETPIQFIKGVGPKLA
ETLGKKGIATVEDALYLLPNRYEDRRQVVPIARLCPGVTSVFSGEVITADVVSTKGGRRFFEVVVRDASGTISFKWFNFN
PAFLKKTWKEGRRGIFTGLVSQFGLQREVHHPDAEWLAEGETVASVMARDPVSFGRVVPVYPLTEGLHQKTLRKVMKGVV
DQYASCVESALPLEVAGRQGLLPLSDALRRVHFPDSDADPRGLEEGKDPANRTLVFDEFFFLELGLAMKKRGVTLESGIA
FTVSHTYTKPLLKLLPFSLTGAQRRVLAEIKEDMMAPHPMHRLVQGDVGCGKTLVALMAALVAVENGYQVAIMAPTEILA
EQHYLNIHRWCDELGVSVTLVTSSLKGKAKKDALERVAGGEAQIVIGTHAVIQDKVEFHRLGLGIVDEQHRFGVLQRGLL
RKKGENPDILVMTATPIPRTLAMTVFGDLSLSVIDELPPGRTPIETRICFESRRKQVYGIIRDEVTKGHQAYVIYPLVEE
SEKSDLKAATQMAEHLANDIFPELRLGILHGRMKPEEKEAVMRSFKAREIDILVATTVIEVGIDVPNATVMVIEHAERFG
LSQLHQLRGRVGRGSEKSRCILMAGERLSEDAEKRLRVMESTTDGFRIAEADLEIRGPGDFLGTRQAGIPDFRVANILRD
GRILEEARQEAFAVAEVDPELRLPRHDKLRTELARRWGGRLELAGIA
>Mature_766_residues
PVVTLAENGQLAIPDDLLKDLGIKPGDPVLLEKTSGGILLSRHAPPSPGAVQSRLHESINRKNLETPIQFIKGVGPKLAE
TLGKKGIATVEDALYLLPNRYEDRRQVVPIARLCPGVTSVFSGEVITADVVSTKGGRRFFEVVVRDASGTISFKWFNFNP
AFLKKTWKEGRRGIFTGLVSQFGLQREVHHPDAEWLAEGETVASVMARDPVSFGRVVPVYPLTEGLHQKTLRKVMKGVVD
QYASCVESALPLEVAGRQGLLPLSDALRRVHFPDSDADPRGLEEGKDPANRTLVFDEFFFLELGLAMKKRGVTLESGIAF
TVSHTYTKPLLKLLPFSLTGAQRRVLAEIKEDMMAPHPMHRLVQGDVGCGKTLVALMAALVAVENGYQVAIMAPTEILAE
QHYLNIHRWCDELGVSVTLVTSSLKGKAKKDALERVAGGEAQIVIGTHAVIQDKVEFHRLGLGIVDEQHRFGVLQRGLLR
KKGENPDILVMTATPIPRTLAMTVFGDLSLSVIDELPPGRTPIETRICFESRRKQVYGIIRDEVTKGHQAYVIYPLVEES
EKSDLKAATQMAEHLANDIFPELRLGILHGRMKPEEKEAVMRSFKAREIDILVATTVIEVGIDVPNATVMVIEHAERFGL
SQLHQLRGRVGRGSEKSRCILMAGERLSEDAEKRLRVMESTTDGFRIAEADLEIRGPGDFLGTRQAGIPDFRVANILRDG
RILEEARQEAFAVAEVDPELRLPRHDKLRTELARRWGGRLELAGIA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=696, Percent_Identity=44.9712643678161, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1787357, Length=398, Percent_Identity=40.9547738693467, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 84776; Mature: 84645

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVTLAENGQLAIPDDLLKDLGIKPGDPVLLEKTSGGILLSRHAPPSPGAVQSRLHESI
CCEEEEECCCCEECCHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHH
NRKNLETPIQFIKGVGPKLAETLGKKGIATVEDALYLLPNRYEDRRQVVPIARLCPGVTS
HHCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHCCCHHH
VFSGEVITADVVSTKGGRRFFEVVVRDASGTISFKWFNFNPAFLKKTWKEGRRGIFTGLV
HHCCCEEEEEHHCCCCCHHEEHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SQFGLQREVHHPDAEWLAEGETVASVMARDPVSFGRVVPVYPLTEGLHQKTLRKVMKGVV
HHHCCCHHCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
DQYASCVESALPLEVAGRQGLLPLSDALRRVHFPDSDADPRGLEEGKDPANRTLVFDEFF
HHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHH
FLELGLAMKKRGVTLESGIAFTVSHTYTKPLLKLLPFSLTGAQRRVLAEIKEDMMAPHPM
HHHHHHHHHHCCCEEECCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
HRLVQGDVGCGKTLVALMAALVAVENGYQVAIMAPTEILAEQHYLNIHRWCDELGVSVTL
HHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEE
VTSSLKGKAKKDALERVAGGEAQIVIGTHAVIQDKVEFHRLGLGIVDEQHRFGVLQRGLL
EECCCCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHH
RKKGENPDILVMTATPIPRTLAMTVFGDLSLSVIDELPPGRTPIETRICFESRRKQVYGI
HHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IRDEVTKGHQAYVIYPLVEESEKSDLKAATQMAEHLANDIFPELRLGILHGRMKPEEKEA
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VMRSFKAREIDILVATTVIEVGIDVPNATVMVIEHAERFGLSQLHQLRGRVGRGSEKSRC
HHHHHCCCCEEEEEEEEHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCCE
ILMAGERLSEDAEKRLRVMESTTDGFRIAEADLEIRGPGDFLGTRQAGIPDFRVANILRD
EEEECCHHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHC
GRILEEARQEAFAVAEVDPELRLPRHDKLRTELARRWGGRLELAGIA
CHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure 
PVVTLAENGQLAIPDDLLKDLGIKPGDPVLLEKTSGGILLSRHAPPSPGAVQSRLHESI
CEEEEECCCCEECCHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHH
NRKNLETPIQFIKGVGPKLAETLGKKGIATVEDALYLLPNRYEDRRQVVPIARLCPGVTS
HHCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHCCCHHH
VFSGEVITADVVSTKGGRRFFEVVVRDASGTISFKWFNFNPAFLKKTWKEGRRGIFTGLV
HHCCCEEEEEHHCCCCCHHEEHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SQFGLQREVHHPDAEWLAEGETVASVMARDPVSFGRVVPVYPLTEGLHQKTLRKVMKGVV
HHHCCCHHCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
DQYASCVESALPLEVAGRQGLLPLSDALRRVHFPDSDADPRGLEEGKDPANRTLVFDEFF
HHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHH
FLELGLAMKKRGVTLESGIAFTVSHTYTKPLLKLLPFSLTGAQRRVLAEIKEDMMAPHPM
HHHHHHHHHHCCCEEECCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
HRLVQGDVGCGKTLVALMAALVAVENGYQVAIMAPTEILAEQHYLNIHRWCDELGVSVTL
HHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEE
VTSSLKGKAKKDALERVAGGEAQIVIGTHAVIQDKVEFHRLGLGIVDEQHRFGVLQRGLL
EECCCCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHH
RKKGENPDILVMTATPIPRTLAMTVFGDLSLSVIDELPPGRTPIETRICFESRRKQVYGI
HHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IRDEVTKGHQAYVIYPLVEESEKSDLKAATQMAEHLANDIFPELRLGILHGRMKPEEKEA
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VMRSFKAREIDILVATTVIEVGIDVPNATVMVIEHAERFGLSQLHQLRGRVGRGSEKSRC
HHHHHCCCCEEEEEEEEHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCCE
ILMAGERLSEDAEKRLRVMESTTDGFRIAEADLEIRGPGDFLGTRQAGIPDFRVANILRD
EEEECCHHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHC
GRILEEARQEAFAVAEVDPELRLPRHDKLRTELARRWGGRLELAGIA
CHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]