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The map label for this gene is pyrR [H]

Identifier: 78222977

GI number: 78222977

Start: 1983311

End: 1983847

Strand: Direct

Name: pyrR [H]

Synonym: Gmet_1768

Alternate gene names: 78222977

Gene position: 1983311-1983847 (Clockwise)

Preceding gene: 78222976

Following gene: 78222978

Centisome position: 49.61

GC content: 59.78

Gene sequence:

>537_bases
GTGGCTGAAGAGAAGACGACCATACTGGATGGGGTTGGCGTGAAACGGGCGCTGACCCGCATCGCCCATGAGATTCTCGA
GCGGAACAAGGGGGTTGCCGACCTGGTTCTCGTTGGAATCAGGACCGGGGGAGTCCACCTGGCCCGGGAGCTGTCGTCCC
GGCTTGAAGAGATCGAAGGAGGGAAAGTGTCGGTGGGCGAGGTTGACATTACCCTCTACCGCGACGATTTCAAAGGGCAC
GCCGTTCATCTGCCGGTGGGGAAGACCGATATCCCGTTCACCGTGGAAAAGAAAAAGGTAATTCTCGTGGATGATGTGCT
CTTCACCGGTCGGACCATCCGCGCCGCCATGGATGCCATCATGGATCATGGCAGGCCCGGCAGCATCCAACTGGCGGTCC
TCATCGACAGGGGACACCGGGAACTCCCCATCAGGGCTGATTTTGTCGGGCGCAACGTCCCCACGAGCCGCAGGGAGAAG
ATCACGGTCCAGTTCGATGCCGATGCCAAGCCGGTGGAAGTGGTTCTGGAAAAGTGA

Upstream 100 bases:

>100_bases
ATACAGTCTTACTGAGCCTTTTCGCGTCGTGCGGAAGGGCTCTTTTCGTGCCTGCCGGCGGAGTCGGCGACAAGGCCCTG
TGAGCGAAAGGAGGGACGAG

Downstream 100 bases:

>100_bases
TTTGCGTCGGGGGCAACCCAGGCGGTTACTTTTGACAGGGCAGGCACGGGGCCTAGCCCTACGCGAGATGGGGGGAAGCG
ATGGGATTCAAGCACAAGGA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MAEEKTTILDGVGVKRALTRIAHEILERNKGVADLVLVGIRTGGVHLARELSSRLEEIEGGKVSVGEVDITLYRDDFKGH
AVHLPVGKTDIPFTVEKKKVILVDDVLFTGRTIRAAMDAIMDHGRPGSIQLAVLIDRGHRELPIRADFVGRNVPTSRREK
ITVQFDADAKPVEVVLEK

Sequences:

>Translated_178_residues
MAEEKTTILDGVGVKRALTRIAHEILERNKGVADLVLVGIRTGGVHLARELSSRLEEIEGGKVSVGEVDITLYRDDFKGH
AVHLPVGKTDIPFTVEKKKVILVDDVLFTGRTIRAAMDAIMDHGRPGSIQLAVLIDRGHRELPIRADFVGRNVPTSRREK
ITVQFDADAKPVEVVLEK
>Mature_177_residues
AEEKTTILDGVGVKRALTRIAHEILERNKGVADLVLVGIRTGGVHLARELSSRLEEIEGGKVSVGEVDITLYRDDFKGHA
VHLPVGKTDIPFTVEKKKVILVDDVLFTGRTIRAAMDAIMDHGRPGSIQLAVLIDRGHRELPIRADFVGRNVPTSRREKI
TVQFDADAKPVEVVLEK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19617; Mature: 19486

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEKTTILDGVGVKRALTRIAHEILERNKGVADLVLVGIRTGGVHLARELSSRLEEIEG
CCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
GKVSVGEVDITLYRDDFKGHAVHLPVGKTDIPFTVEKKKVILVDDVLFTGRTIRAAMDAI
CEEEECEEEEEEEECCCCCCEEEECCCCCCCCEEECCCEEEEEECEECCCCHHHHHHHHH
MDHGRPGSIQLAVLIDRGHRELPIRADFVGRNVPTSRREKITVQFDADAKPVEVVLEK
HHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC
>Mature Secondary Structure 
AEEKTTILDGVGVKRALTRIAHEILERNKGVADLVLVGIRTGGVHLARELSSRLEEIEG
CCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
GKVSVGEVDITLYRDDFKGHAVHLPVGKTDIPFTVEKKKVILVDDVLFTGRTIRAAMDAI
CEEEECEEEEEEEECCCCCCEEEECCCCCCCCEEECCCEEEEEECEECCCCHHHHHHHHH
MDHGRPGSIQLAVLIDRGHRELPIRADFVGRNVPTSRREKITVQFDADAKPVEVVLEK
HHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA