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The map label for this gene is coaD

Identifier: 78222968

GI number: 78222968

Start: 1974244

End: 1974735

Strand: Reverse

Name: coaD

Synonym: Gmet_1759

Alternate gene names: 78222968

Gene position: 1974735-1974244 (Counterclockwise)

Preceding gene: 78222969

Following gene: 78222967

Centisome position: 49.4

GC content: 53.46

Gene sequence:

>492_bases
ATGCCTAGAAAAGTTGCCGTCTATCCCGGCTCCTTCGACCCCATCACCTACGGTCATCTTGACATCATAGACCGGGGGCT
GCGAATCTTCGACGAAATCATCGTTGCCGTGGCCCGTAATTCGGCAAAGAACTCCCTCTTTTCCATTGATGAACGGGTCG
ACATGATCCAGCGTGTGCTGGCGGACAACGTCAGGGCGCGCGTTGACACTTTCGACGGTCTTCTGGTAGATTACGTCCTC
TCCCAGAACGCAACGGTCATCATCCGAGGGCTTCGGGCAATATCCGATTTCGAATACGAATTCCAGATCGCCCAGATGAA
TAGAAGCATCTCCCAGGATGTTGAAACGCTCTTCATGATGACATCGGTTCCCTTCGGATACCTGTCGTCATCCATCGTCA
AGGAAGTAAGTTCCCTGAACGGCCCCATCGACGGTCTGGTCCCTCCCCTGGTGCGGGAGGCCCTCAAGGATAAGTTCTCA
AAACCAAGATAG

Upstream 100 bases:

>100_bases
AAGTTTTTCCTGAAAGATTCGGTGCATTGCAGCAGTTCGACCGGAGGGTTTACGGCGACACCGCCCTCACTTTTTTCCAG
AAAGGGACTTCCTGACGACC

Downstream 100 bases:

>100_bases
ACTTGAGCTAGAGCGGACGCTACCCTTCAACGGAAGAAGGCGGGGAATACTCAGGTACTACCTCGCCTTTTTTCATATTC
AACCGGCACGAAGAGACGAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MPRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVLADNVRARVDTFDGLLVDYVL
SQNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFS
KPR

Sequences:

>Translated_163_residues
MPRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVLADNVRARVDTFDGLLVDYVL
SQNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFS
KPR
>Mature_162_residues
PRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVLADNVRARVDTFDGLLVDYVLS
QNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFSK
PR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=42.4050632911392, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_GEOMG (Q39UT4)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384715.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q39UT4
- SMR:   Q39UT4
- STRING:   Q39UT4
- GeneID:   3741435
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1759
- NMPDR:   fig|269799.3.peg.2076
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q39UT4
- ProtClustDB:   PRK00168
- BioCyc:   GMET269799:GMET_1759-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18314; Mature: 18183

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVL
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ADNVRARVDTFDGLLVDYVLSQNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMM
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFSKPR
HHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRKVAVYPGSFDPITYGHLDIIDRGLRIFDEIIVAVARNSAKNSLFSIDERVDMIQRVL
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ADNVRARVDTFDGLLVDYVLSQNATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMM
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSVPFGYLSSSIVKEVSSLNGPIDGLVPPLVREALKDKFSKPR
HHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA