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The map label for this gene is mmpL12 [H]

Identifier: 78222908

GI number: 78222908

Start: 1904939

End: 1907482

Strand: Direct

Name: mmpL12 [H]

Synonym: Gmet_1699

Alternate gene names: 78222908

Gene position: 1904939-1907482 (Clockwise)

Preceding gene: 78222907

Following gene: 78222909

Centisome position: 47.65

GC content: 63.25

Gene sequence:

>2544_bases
ATGCTGAACAGAGTAACCGGCGCGACCCAGTCCGCCATCAAACGCCACCTGTCCTGGATTTTCAGGGTAACCAGCACGCG
GCCCGTGATGGTTTTTGCCGCGTTTGTTTTTTTTGTCGCTCTTTCAGTCGTCTCGATTCTTACCACTCGTTTCGAGGCCG
ATGTCTTCAAACTCTTTCCGGCGCGCCAAGGGGCACTCCGTCTCTTCCTCGATTCCCTCCAGTGGACCGGTAGTGCCAAC
GAGGCCTATTTCCTGCTCGAAGGGGAGAAGGAGCGCCTCGTCCCGGAGGCCGAGGCGTTTGCCGGCCGACTGAAGGAGCT
TCGGGTCGACGGGGCACCGGCCTTCCGCCGGGTCATCTACCGGATCTACGACCCGTCGGAGGCCAGGGCCTTTGCGGACT
TCATCGGATATGCCGTGGTGCACCCCGGTTCTTTCCTCGAACCGGCGGATGTGCCGGCTTACCTGGGGCGCCTGGCGCCG
AAGGCCATGGACGAGGCCCTCCTCCGGACGGGAACGGAGCTGGCCAGCCAGGCCGGAGCCGGTCTGCGGGACCTGGTCGT
GGCCGACCCCCTGGCCCTGCGGGATCTCGTAACTCCTCGGCTGAAACGGGGAAGCCAGGCTCTCGATCTGGACCCGAACT
CCCCCTATTTCCTCTCCCGGGACGGCCGAGTGCTGATCATCATTGCCGAGCCTGCCCGTCCGGTGCAGGACATGGTCTTT
GCCCGGAAGCTGGCCAAGGGGATCAACCAGGCCAGGGAAGGGGCGCGGGTCCGGATATCCTGCGCCGGGGCCCACCTGTC
GGCGGTCATCGACGAGGCGGCCATGAAGGGGGACATCCTCTCCTGCATCCTCTCGTCCCTTGTGGTGGTCCTGCTGCTTT
TCTTCGCCACCTATCGGCGGGTGCTGCCGACGCTCCTTCTGCCAGTCATCATCGGGGGGGGCGTGGTGTTGGCCTTGGGG
GTGGCCGGCGCCTTCCTTCCGTCGATCCATATCATCTCCTTCGCTTTCATGGCGCTCATCATCGGCCTCGGCACCGACTA
TTCGGTCCACCTCTATGACCGTTATCACATGGAGCGCTGCGCCGGGCTGACGCCGGAAGAGGCCCTGCGGCTCGCCGTCA
CCGACACGGGACACGGCATCTTCACCGCCGCCACAACTACTGCCATGCCGTTTCTCACCCTGGCCATCACCGACGTGCGG
GCACTCTCTGAACTGGGTATCCTGGTGGGACTCGGGGTGCTCTTTTCCCTCTATACGACCTTGTTCCTCCTGCCGCCTCT
GCTTCTCTTCATGGAGCGCCTGTCGCCCCGTTTTGTCTACCGGCCGCTTCCCGGCTTCGGCCTGGCCGCACTCTGGCGGG
GTAGCCGTCGCCGGGGCCGGCTGGTGAAAGTGGTGTCGATTCTCGCCGTGGCGGCTTTCTGCATCATGGCCTGCTATACC
ACCTTCGAGGGGGAGCTGAAGAACCTCCAGCCGCGTCATTCCGAGGCGTTCCTCACCCAGGAGAAGATCGAGCGGCACCT
GAGCCTGAGTCCGAAACAGATGCTGGTGGCGGTGGAGGGTAAAGACCTTGGCGATGTGCTGGCACGGGGGGCGCGGGTTG
ATCTCCTTGTGGAGCGTTACCGTCAACGGGGAGAGCTGGCGGCTTTCTCCAGTCTGGGCCAGCTGGTTAACGACGACACG
GCGCGTGCCGAGGTTTCACGTCAGATCGACCAGGGCCTTGCGGGGAGGGATCCGGGCAGGGCGCTCAAGGATGCTTTGGA
GCGGCAAGGGTTTGCGGTGGAACCGTTTGAAGGGACCATCGCCGGCCTTGTCTCCCTCCGGGGAAATGGGTCCTCATTGT
CAACCGAAGCAATTACCCGGCTTGCCGCATCGCCGCTCAAGGGGGCCGTGGACCGGCACCTGATCAGAGATGCTGCCGGT
TACCACCTGCTGGTCCACCTTTTCTACAAAGGGGCTGAATTTCCCCAGGATGCCTTCCTGAAAGAACTGTCGGCCATCGA
CCCGTCGGCCCGTGCCACCAGCGTCGATCTGGTGAGTCGTCAGCTGGCTGCCGACGTGAAGCAGAGTTTTCTCTGGGGAT
TTGTCATTGGCGGGGCACTGGTGATCTTTCTCCTCCTCTCCCATTTCTCCTCGATGCTGGGACTATTTGCCTCTTTCTAT
CCAGTTTTCGCAGGCATTGCCGCCATGCTCGGCATCATGGCCGTCAGTGGCATGGGAATCAATTTCATGAACGCCATGGT
CCTGGTGACGATTCTTGGCATGGGGAACGACTACGGAATGCACATAGCCCACCGAGTGGAGGGGAAGGACGAGCCGGAGC
GGGAGTTCGTGCAGGCCGGCCGGGCGGTGCTCCTGTCGGCCCTCACCACCATCGCCGGCTTCGGCTCCCTGGCCTTTGCC
GACTACGGAGCCCTTGCCTCCATCGGCTGGGCCACCAACTACGGTGTCGGGGCCACCATGATTTTTGCGCTCGTGTCGCT
TCCCGCGTTTCTCGTGGCGGGACGGCGGCGATCTCCGGCCCCTGGCAGGGAGATACGCCCATGA

Upstream 100 bases:

>100_bases
ACTCTCATCACTTTCAGCCGGGTGCGCAAAAACTCCGGGCTGACGGATAAAGATTTTCGTATAAATTAACCCCCCCTTCC
TTCCAGGAGTCTCCCCACCC

Downstream 100 bases:

>100_bases
AGTCCCGTCCCCGCCTCCTCTTGGTATATCCCGCCACCCACAAACTCGGGTGGGTGCGGCGGTTCCAGCTTCCCTCCCTC
TCCCTGAAACAGGTGGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 847

Protein sequence:

>847_residues
MLNRVTGATQSAIKRHLSWIFRVTSTRPVMVFAAFVFFVALSVVSILTTRFEADVFKLFPARQGALRLFLDSLQWTGSAN
EAYFLLEGEKERLVPEAEAFAGRLKELRVDGAPAFRRVIYRIYDPSEARAFADFIGYAVVHPGSFLEPADVPAYLGRLAP
KAMDEALLRTGTELASQAGAGLRDLVVADPLALRDLVTPRLKRGSQALDLDPNSPYFLSRDGRVLIIIAEPARPVQDMVF
ARKLAKGINQAREGARVRISCAGAHLSAVIDEAAMKGDILSCILSSLVVVLLLFFATYRRVLPTLLLPVIIGGGVVLALG
VAGAFLPSIHIISFAFMALIIGLGTDYSVHLYDRYHMERCAGLTPEEALRLAVTDTGHGIFTAATTTAMPFLTLAITDVR
ALSELGILVGLGVLFSLYTTLFLLPPLLLFMERLSPRFVYRPLPGFGLAALWRGSRRRGRLVKVVSILAVAAFCIMACYT
TFEGELKNLQPRHSEAFLTQEKIERHLSLSPKQMLVAVEGKDLGDVLARGARVDLLVERYRQRGELAAFSSLGQLVNDDT
ARAEVSRQIDQGLAGRDPGRALKDALERQGFAVEPFEGTIAGLVSLRGNGSSLSTEAITRLAASPLKGAVDRHLIRDAAG
YHLLVHLFYKGAEFPQDAFLKELSAIDPSARATSVDLVSRQLAADVKQSFLWGFVIGGALVIFLLLSHFSSMLGLFASFY
PVFAGIAAMLGIMAVSGMGINFMNAMVLVTILGMGNDYGMHIAHRVEGKDEPEREFVQAGRAVLLSALTTIAGFGSLAFA
DYGALASIGWATNYGVGATMIFALVSLPAFLVAGRRRSPAPGREIRP

Sequences:

>Translated_847_residues
MLNRVTGATQSAIKRHLSWIFRVTSTRPVMVFAAFVFFVALSVVSILTTRFEADVFKLFPARQGALRLFLDSLQWTGSAN
EAYFLLEGEKERLVPEAEAFAGRLKELRVDGAPAFRRVIYRIYDPSEARAFADFIGYAVVHPGSFLEPADVPAYLGRLAP
KAMDEALLRTGTELASQAGAGLRDLVVADPLALRDLVTPRLKRGSQALDLDPNSPYFLSRDGRVLIIIAEPARPVQDMVF
ARKLAKGINQAREGARVRISCAGAHLSAVIDEAAMKGDILSCILSSLVVVLLLFFATYRRVLPTLLLPVIIGGGVVLALG
VAGAFLPSIHIISFAFMALIIGLGTDYSVHLYDRYHMERCAGLTPEEALRLAVTDTGHGIFTAATTTAMPFLTLAITDVR
ALSELGILVGLGVLFSLYTTLFLLPPLLLFMERLSPRFVYRPLPGFGLAALWRGSRRRGRLVKVVSILAVAAFCIMACYT
TFEGELKNLQPRHSEAFLTQEKIERHLSLSPKQMLVAVEGKDLGDVLARGARVDLLVERYRQRGELAAFSSLGQLVNDDT
ARAEVSRQIDQGLAGRDPGRALKDALERQGFAVEPFEGTIAGLVSLRGNGSSLSTEAITRLAASPLKGAVDRHLIRDAAG
YHLLVHLFYKGAEFPQDAFLKELSAIDPSARATSVDLVSRQLAADVKQSFLWGFVIGGALVIFLLLSHFSSMLGLFASFY
PVFAGIAAMLGIMAVSGMGINFMNAMVLVTILGMGNDYGMHIAHRVEGKDEPEREFVQAGRAVLLSALTTIAGFGSLAFA
DYGALASIGWATNYGVGATMIFALVSLPAFLVAGRRRSPAPGREIRP
>Mature_847_residues
MLNRVTGATQSAIKRHLSWIFRVTSTRPVMVFAAFVFFVALSVVSILTTRFEADVFKLFPARQGALRLFLDSLQWTGSAN
EAYFLLEGEKERLVPEAEAFAGRLKELRVDGAPAFRRVIYRIYDPSEARAFADFIGYAVVHPGSFLEPADVPAYLGRLAP
KAMDEALLRTGTELASQAGAGLRDLVVADPLALRDLVTPRLKRGSQALDLDPNSPYFLSRDGRVLIIIAEPARPVQDMVF
ARKLAKGINQAREGARVRISCAGAHLSAVIDEAAMKGDILSCILSSLVVVLLLFFATYRRVLPTLLLPVIIGGGVVLALG
VAGAFLPSIHIISFAFMALIIGLGTDYSVHLYDRYHMERCAGLTPEEALRLAVTDTGHGIFTAATTTAMPFLTLAITDVR
ALSELGILVGLGVLFSLYTTLFLLPPLLLFMERLSPRFVYRPLPGFGLAALWRGSRRRGRLVKVVSILAVAAFCIMACYT
TFEGELKNLQPRHSEAFLTQEKIERHLSLSPKQMLVAVEGKDLGDVLARGARVDLLVERYRQRGELAAFSSLGQLVNDDT
ARAEVSRQIDQGLAGRDPGRALKDALERQGFAVEPFEGTIAGLVSLRGNGSSLSTEAITRLAASPLKGAVDRHLIRDAAG
YHLLVHLFYKGAEFPQDAFLKELSAIDPSARATSVDLVSRQLAADVKQSFLWGFVIGGALVIFLLLSHFSSMLGLFASFY
PVFAGIAAMLGIMAVSGMGINFMNAMVLVTILGMGNDYGMHIAHRVEGKDEPEREFVQAGRAVLLSALTTIAGFGSLAFA
DYGALASIGWATNYGVGATMIFALVSLPAFLVAGRRRSPAPGREIRP

Specific function: Unknown

COG id: COG1033

COG function: function code R; Predicted exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 91789; Mature: 91789

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRVTGATQSAIKRHLSWIFRVTSTRPVMVFAAFVFFVALSVVSILTTRFEADVFKLFP
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARQGALRLFLDSLQWTGSANEAYFLLEGEKERLVPEAEAFAGRLKELRVDGAPAFRRVIY
CCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RIYDPSEARAFADFIGYAVVHPGSFLEPADVPAYLGRLAPKAMDEALLRTGTELASQAGA
HHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
GLRDLVVADPLALRDLVTPRLKRGSQALDLDPNSPYFLSRDGRVLIIIAEPARPVQDMVF
CHHHHHHCCCHHHHHHHCHHHHCCCCEEECCCCCCEEECCCCEEEEEEECCCCCHHHHHH
ARKLAKGINQAREGARVRISCAGAHLSAVIDEAAMKGDILSCILSSLVVVLLLFFATYRR
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLPTLLLPVIIGGGVVLALGVAGAFLPSIHIISFAFMALIIGLGTDYSVHLYDRYHMERC
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
AGLTPEEALRLAVTDTGHGIFTAATTTAMPFLTLAITDVRALSELGILVGLGVLFSLYTT
CCCCHHHHEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLLPPLLLFMERLSPRFVYRPLPGFGLAALWRGSRRRGRLVKVVSILAVAAFCIMACYT
HHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TFEGELKNLQPRHSEAFLTQEKIERHLSLSPKQMLVAVEGKDLGDVLARGARVDLLVERY
HHCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEECCCCHHHHHHCCCHHHHHHHHH
RQRGELAAFSSLGQLVNDDTARAEVSRQIDQGLAGRDPGRALKDALERQGFAVEPFEGTI
HHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCCCHHH
AGLVSLRGNGSSLSTEAITRLAASPLKGAVDRHLIRDAAGYHLLVHLFYKGAEFPQDAFL
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KELSAIDPSARATSVDLVSRQLAADVKQSFLWGFVIGGALVIFLLLSHFSSMLGLFASFY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVFAGIAAMLGIMAVSGMGINFMNAMVLVTILGMGNDYGMHIAHRVEGKDEPEREFVQAG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHH
RAVLLSALTTIAGFGSLAFADYGALASIGWATNYGVGATMIFALVSLPAFLVAGRRRSPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PGREIRP
CCCCCCC
>Mature Secondary Structure
MLNRVTGATQSAIKRHLSWIFRVTSTRPVMVFAAFVFFVALSVVSILTTRFEADVFKLFP
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARQGALRLFLDSLQWTGSANEAYFLLEGEKERLVPEAEAFAGRLKELRVDGAPAFRRVIY
CCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RIYDPSEARAFADFIGYAVVHPGSFLEPADVPAYLGRLAPKAMDEALLRTGTELASQAGA
HHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
GLRDLVVADPLALRDLVTPRLKRGSQALDLDPNSPYFLSRDGRVLIIIAEPARPVQDMVF
CHHHHHHCCCHHHHHHHCHHHHCCCCEEECCCCCCEEECCCCEEEEEEECCCCCHHHHHH
ARKLAKGINQAREGARVRISCAGAHLSAVIDEAAMKGDILSCILSSLVVVLLLFFATYRR
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLPTLLLPVIIGGGVVLALGVAGAFLPSIHIISFAFMALIIGLGTDYSVHLYDRYHMERC
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
AGLTPEEALRLAVTDTGHGIFTAATTTAMPFLTLAITDVRALSELGILVGLGVLFSLYTT
CCCCHHHHEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLLPPLLLFMERLSPRFVYRPLPGFGLAALWRGSRRRGRLVKVVSILAVAAFCIMACYT
HHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TFEGELKNLQPRHSEAFLTQEKIERHLSLSPKQMLVAVEGKDLGDVLARGARVDLLVERY
HHCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEECCCCHHHHHHCCCHHHHHHHHH
RQRGELAAFSSLGQLVNDDTARAEVSRQIDQGLAGRDPGRALKDALERQGFAVEPFEGTI
HHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCCCHHH
AGLVSLRGNGSSLSTEAITRLAASPLKGAVDRHLIRDAAGYHLLVHLFYKGAEFPQDAFL
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KELSAIDPSARATSVDLVSRQLAADVKQSFLWGFVIGGALVIFLLLSHFSSMLGLFASFY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVFAGIAAMLGIMAVSGMGINFMNAMVLVTILGMGNDYGMHIAHRVEGKDEPEREFVQAG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHH
RAVLLSALTTIAGFGSLAFADYGALASIGWATNYGVGATMIFALVSLPAFLVAGRRRSPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PGREIRP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]