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The map label for this gene is fabD [H]

Identifier: 78222900

GI number: 78222900

Start: 1898189

End: 1899019

Strand: Direct

Name: fabD [H]

Synonym: Gmet_1691

Alternate gene names: 78222900

Gene position: 1898189-1899019 (Clockwise)

Preceding gene: 78222899

Following gene: 78222901

Centisome position: 47.49

GC content: 62.33

Gene sequence:

>831_bases
ATGTTTCCCGGCCAACCCCTGACCTTTGAAACAACGGTTCCCGACGATCCCGATTTCCGGCAGGCAACGGCACTGACCCT
GGACCGGACTGGCCTTGACCTGGCTGACTCTGCCTTGCTCGGTGAGGGACTGACGGAGCATGTACGGCTTCAGGTCTACG
GCGTAGCGATGAGCCTTTACCGCTGCCGGCGGTTGCGTCGTGAAGGGACGGTTCCCGCAATCATCGCCGAGCACAGCATG
GGGATCTATCCGGCCATGGCCGCATGCGGAGCCCTTGACGACGGGGATGCCCTGGAATTGACGTGCCGCATCGGGGCCTG
CATCGCTGCCATGGGGACACGGAGGTCCTACGCCCTCGGCTGCGTCACGGGACTCACCGCTGCCCCGCTCATGGCCGTGG
CCGAAAACAACGGCGTCTTTCTGGCAAACTACAACACATCGCGCCATTTCCTCCTCTCCGGCGAACGGCGGAATGTGGAG
GATGCCGTGGCCGAAGCGTTGAACAACGGCGCGTTTACGGCTCGAAGCTTCCCCTGCGATGCGCCGCTTCATTCGCCTCT
TATGGAGGAGGTGGCCGGCGAGCTGCGGGAGGTTATCGGTGACTACCGTTTCCGGGAACCGGTGCTTCCGCTCATGAGCC
ACATTGACCAGGATTATCTTTCTGCTGCCGACCTGCCGGAGTTTCTGGTGCGGGAACTCTCGCTCCCCGTTTACTGGGAG
CGGACTTTCCAGGCGCTCTCCGATGCCGGTGTGAGCCGTTTCGTGGAGGTTGGCGTCGGCGATTCCCTGAAAAAGTACAA
CCGCTGGATTGCCAGCGAAGGGGGCAGGTGA

Upstream 100 bases:

>100_bases
GAATCTTCAAGGCCCACCGCTCGGTCCAGGTATTCGCCCCCATGAATTTCGGATTCCGCAGCGCTATCCGCCGGAAGGGG
AGGGTCGCGTGATCTGCTTC

Downstream 100 bases:

>100_bases
GGGGCGTGAGACACCATGAGACTCAGATAAAGGTGCGCTTCAACGAGATTGACGCCTACCGGGTCGCCTGGCACGGACAC
TATGTTGCCTGGATGGAGGT

Product: Acyl transferase region

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MFPGQPLTFETTVPDDPDFRQATALTLDRTGLDLADSALLGEGLTEHVRLQVYGVAMSLYRCRRLRREGTVPAIIAEHSM
GIYPAMAACGALDDGDALELTCRIGACIAAMGTRRSYALGCVTGLTAAPLMAVAENNGVFLANYNTSRHFLLSGERRNVE
DAVAEALNNGAFTARSFPCDAPLHSPLMEEVAGELREVIGDYRFREPVLPLMSHIDQDYLSAADLPEFLVRELSLPVYWE
RTFQALSDAGVSRFVEVGVGDSLKKYNRWIASEGGR

Sequences:

>Translated_276_residues
MFPGQPLTFETTVPDDPDFRQATALTLDRTGLDLADSALLGEGLTEHVRLQVYGVAMSLYRCRRLRREGTVPAIIAEHSM
GIYPAMAACGALDDGDALELTCRIGACIAAMGTRRSYALGCVTGLTAAPLMAVAENNGVFLANYNTSRHFLLSGERRNVE
DAVAEALNNGAFTARSFPCDAPLHSPLMEEVAGELREVIGDYRFREPVLPLMSHIDQDYLSAADLPEFLVRELSLPVYWE
RTFQALSDAGVSRFVEVGVGDSLKKYNRWIASEGGR
>Mature_276_residues
MFPGQPLTFETTVPDDPDFRQATALTLDRTGLDLADSALLGEGLTEHVRLQVYGVAMSLYRCRRLRREGTVPAIIAEHSM
GIYPAMAACGALDDGDALELTCRIGACIAAMGTRRSYALGCVTGLTAAPLMAVAENNGVFLANYNTSRHFLLSGERRNVE
DAVAEALNNGAFTARSFPCDAPLHSPLMEEVAGELREVIGDYRFREPVLPLMSHIDQDYLSAADLPEFLVRELSLPVYWE
RTFQALSDAGVSRFVEVGVGDSLKKYNRWIASEGGR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Escherichia coli, GI1787334, Length=220, Percent_Identity=28.1818181818182, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 30137; Mature: 30137

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPGQPLTFETTVPDDPDFRQATALTLDRTGLDLADSALLGEGLTEHVRLQVYGVAMSLY
CCCCCCCEEECCCCCCCCCHHHHEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RCRRLRREGTVPAIIAEHSMGIYPAMAACGALDDGDALELTCRIGACIAAMGTRRSYALG
HHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCHHHHH
CVTGLTAAPLMAVAENNGVFLANYNTSRHFLLSGERRNVEDAVAEALNNGAFTARSFPCD
HHHHHHHHHHHEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCCC
APLHSPLMEEVAGELREVIGDYRFREPVLPLMSHIDQDYLSAADLPEFLVRELSLPVYWE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCHHHH
RTFQALSDAGVSRFVEVGVGDSLKKYNRWIASEGGR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPGQPLTFETTVPDDPDFRQATALTLDRTGLDLADSALLGEGLTEHVRLQVYGVAMSLY
CCCCCCCEEECCCCCCCCCHHHHEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RCRRLRREGTVPAIIAEHSMGIYPAMAACGALDDGDALELTCRIGACIAAMGTRRSYALG
HHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCHHHHH
CVTGLTAAPLMAVAENNGVFLANYNTSRHFLLSGERRNVEDAVAEALNNGAFTARSFPCD
HHHHHHHHHHHEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCCC
APLHSPLMEEVAGELREVIGDYRFREPVLPLMSHIDQDYLSAADLPEFLVRELSLPVYWE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHCCCHHHHHHHCCCCHHHH
RTFQALSDAGVSRFVEVGVGDSLKKYNRWIASEGGR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]