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The map label for this gene is cph1 [H]

Identifier: 78222876

GI number: 78222876

Start: 1872375

End: 1873988

Strand: Reverse

Name: cph1 [H]

Synonym: Gmet_1667

Alternate gene names: 78222876

Gene position: 1873988-1872375 (Counterclockwise)

Preceding gene: 78222877

Following gene: 78222875

Centisome position: 46.88

GC content: 55.95

Gene sequence:

>1614_bases
ATGCGGATATTTCGACAAGCGACGATAAAGCGGAAAATGATGCTGATCAGCATGGCGACGACCGGCGTAGCACTGCTCAT
ATCCGGGGTTGTCCTGATATTCAATGAGATGGTTTCATACCGCCGCTCCCTGGTGAACAGCTTGACGGTTCAGGCACGGA
TCACCGGCAGCAACAGTACGGCGGCACTGAGCTTTAACAATCCGAGGGTGGCACATGAAATGTTGGGGGCTCTGAGCGCT
GCGCCCAATATCGTCCAAGCGACAATTCATACCCGCGAGGGTGAGGTATTTGCCCGTTACCTGCGAACCGGGGAGAGAGT
CAAACCGATCTCCCCTCCCCCGAAGAACGGCTACTCTATTGCTGCCAACAGCATTGTTGTGGTCGAGCCCATCATCCTCG
ACCAGGAGCCGATCGGCACCATACTGATCGAATCGGATCTCAGAGAACTGCATGGACGCTTGGGGTGGTATACAGCGATC
ATGGTCATCGTCTTCTCGGGATCGCTCTGGGTTGCCTTCCTCCTGTTGTCAAGGATGCAACGGGCTGTCACCAGCCCCAT
CCTTGATCTGGTACAGGTTATGGGTACCGTTTCCCGCGAGGGTGACTATTCCGTGCGGGCCTCGGCATGGAATGATGACG
AACTCGGCTCCCTGGCGCAAGGGTTCAACGAGATGCTGGTCCAGATTCAGAGCAGGGATAACGAGTTGGAGTTGCATCGC
AGACATCTTGAGCAAACAGTGGCAAGCCGTACGGCGGAACTCGCGGACGCCAACGAACAGCTGCAGCGTGAGCTTGTGGA
GCGCCAGCGCGCTGAAGAGCAGCTGCAACGTTATTCCGGGGAACTGCGGGACATCAACGATGAGCTTAAAAGCTTTGCCT
ATATGGTCTCGCACGATCTTCGGGCACCGCTCATCAACATTAAAGGGTTTGCTTCCGAGCTCGATCTGGCGCTGAAGGAC
GCGTTCCCCCTTCTTGAGCAATCTCTTACCACGCTGAGCGGAAAAGAACGTGAGCAGGTCAGGTTCGCCTTGCAGCAGGA
TGCACCAGAGGCGCTCGGATTCATCAGCTCTTCGGTCAACCGGATGGATGCGCTCATCAACGCGGTGTTGCAACTCTCCT
ATATAGGGCGGCGAGAAATCAGGCTCGAAACAGTCTGCGTCACGACGATCGTCAATTCAATCCTGCAATCGTTGCGACAC
CAGCTTGAGCAGCGCAGCGTCACGGTCACGGTCGGCGAGCTTCCGGAAATCATCATAGACAAGATGGCGCTTGAGCAGAT
CATTGGCAACCTGCTGGACAATGCGGTCAAGTACCTGGCACCGGAACGCCCCGGACGCATCGAAGTCAACGCCTACGAAG
AAGCGGATGGAACGACTCTCCGCATCAGCGACAACGGACGCGGAATAGCACCGGGGGATATGGGAAAAGTGTTTGAGCTG
TTCCGTCGGGGAAACTGCCCGGATACCGTGGGCGAAGGGATGGGCCTCGCCTACGTGAAGACCCTTGTGCGTCGCTTCGG
GGGACGGATCGAGTGCGAATCAATACCGGGAGTGGGGACAACCTTTAGTGTCTTTATCCCAATACAATCATATTCAGGGA
AGGAGTATCAGTAA

Upstream 100 bases:

>100_bases
TGAAATCAATGTGGATGCCGGGAAACGCGCAGGCCTGCAGATAAGCTCCAAACTCCTGAGCCTGGCGCGAATCGTTCGCG
ATTCGCAATAGAGTGTCGGT

Downstream 100 bases:

>100_bases
GCTCTCCGGCGCGCCTCCTTTCTTGACATAAGGGGTATTGTTGCTAGGGTTTATTATCGTCATTCTCAGACATGCGTGAA
ACAGCATTACTGCCGACTGT

Product: histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MRIFRQATIKRKMMLISMATTGVALLISGVVLIFNEMVSYRRSLVNSLTVQARITGSNSTAALSFNNPRVAHEMLGALSA
APNIVQATIHTREGEVFARYLRTGERVKPISPPPKNGYSIAANSIVVVEPIILDQEPIGTILIESDLRELHGRLGWYTAI
MVIVFSGSLWVAFLLLSRMQRAVTSPILDLVQVMGTVSREGDYSVRASAWNDDELGSLAQGFNEMLVQIQSRDNELELHR
RHLEQTVASRTAELADANEQLQRELVERQRAEEQLQRYSGELRDINDELKSFAYMVSHDLRAPLINIKGFASELDLALKD
AFPLLEQSLTTLSGKEREQVRFALQQDAPEALGFISSSVNRMDALINAVLQLSYIGRREIRLETVCVTTIVNSILQSLRH
QLEQRSVTVTVGELPEIIIDKMALEQIIGNLLDNAVKYLAPERPGRIEVNAYEEADGTTLRISDNGRGIAPGDMGKVFEL
FRRGNCPDTVGEGMGLAYVKTLVRRFGGRIECESIPGVGTTFSVFIPIQSYSGKEYQ

Sequences:

>Translated_537_residues
MRIFRQATIKRKMMLISMATTGVALLISGVVLIFNEMVSYRRSLVNSLTVQARITGSNSTAALSFNNPRVAHEMLGALSA
APNIVQATIHTREGEVFARYLRTGERVKPISPPPKNGYSIAANSIVVVEPIILDQEPIGTILIESDLRELHGRLGWYTAI
MVIVFSGSLWVAFLLLSRMQRAVTSPILDLVQVMGTVSREGDYSVRASAWNDDELGSLAQGFNEMLVQIQSRDNELELHR
RHLEQTVASRTAELADANEQLQRELVERQRAEEQLQRYSGELRDINDELKSFAYMVSHDLRAPLINIKGFASELDLALKD
AFPLLEQSLTTLSGKEREQVRFALQQDAPEALGFISSSVNRMDALINAVLQLSYIGRREIRLETVCVTTIVNSILQSLRH
QLEQRSVTVTVGELPEIIIDKMALEQIIGNLLDNAVKYLAPERPGRIEVNAYEEADGTTLRISDNGRGIAPGDMGKVFEL
FRRGNCPDTVGEGMGLAYVKTLVRRFGGRIECESIPGVGTTFSVFIPIQSYSGKEYQ
>Mature_537_residues
MRIFRQATIKRKMMLISMATTGVALLISGVVLIFNEMVSYRRSLVNSLTVQARITGSNSTAALSFNNPRVAHEMLGALSA
APNIVQATIHTREGEVFARYLRTGERVKPISPPPKNGYSIAANSIVVVEPIILDQEPIGTILIESDLRELHGRLGWYTAI
MVIVFSGSLWVAFLLLSRMQRAVTSPILDLVQVMGTVSREGDYSVRASAWNDDELGSLAQGFNEMLVQIQSRDNELELHR
RHLEQTVASRTAELADANEQLQRELVERQRAEEQLQRYSGELRDINDELKSFAYMVSHDLRAPLINIKGFASELDLALKD
AFPLLEQSLTTLSGKEREQVRFALQQDAPEALGFISSSVNRMDALINAVLQLSYIGRREIRLETVCVTTIVNSILQSLRH
QLEQRSVTVTVGELPEIIIDKMALEQIIGNLLDNAVKYLAPERPGRIEVNAYEEADGTTLRISDNGRGIAPGDMGKVFEL
FRRGNCPDTVGEGMGLAYVKTLVRRFGGRIECESIPGVGTTFSVFIPIQSYSGKEYQ

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=465, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=25.9259259259259, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=264, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=278, Percent_Identity=28.4172661870504, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=25.8196721311475, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=24.8175182481752, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790567, Length=100, Percent_Identity=39, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=24.8945147679325, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59723; Mature: 59723

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFRQATIKRKMMLISMATTGVALLISGVVLIFNEMVSYRRSLVNSLTVQARITGSNST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCE
AALSFNNPRVAHEMLGALSAAPNIVQATIHTREGEVFARYLRTGERVKPISPPPKNGYSI
EEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEE
AANSIVVVEPIILDQEPIGTILIESDLRELHGRLGWYTAIMVIVFSGSLWVAFLLLSRMQ
ECCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RAVTSPILDLVQVMGTVSREGDYSVRASAWNDDELGSLAQGFNEMLVQIQSRDNELELHR
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RHLEQTVASRTAELADANEQLQRELVERQRAEEQLQRYSGELRDINDELKSFAYMVSHDL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
RAPLINIKGFASELDLALKDAFPLLEQSLTTLSGKEREQVRFALQQDAPEALGFISSSVN
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
RMDALINAVLQLSYIGRREIRLETVCVTTIVNSILQSLRHQLEQRSVTVTVGELPEIIID
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
KMALEQIIGNLLDNAVKYLAPERPGRIEVNAYEEADGTTLRISDNGRGIAPGDMGKVFEL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHH
FRRGNCPDTVGEGMGLAYVKTLVRRFGGRIECESIPGVGTTFSVFIPIQSYSGKEYQ
HHCCCCCCHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MRIFRQATIKRKMMLISMATTGVALLISGVVLIFNEMVSYRRSLVNSLTVQARITGSNST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCE
AALSFNNPRVAHEMLGALSAAPNIVQATIHTREGEVFARYLRTGERVKPISPPPKNGYSI
EEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEE
AANSIVVVEPIILDQEPIGTILIESDLRELHGRLGWYTAIMVIVFSGSLWVAFLLLSRMQ
ECCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RAVTSPILDLVQVMGTVSREGDYSVRASAWNDDELGSLAQGFNEMLVQIQSRDNELELHR
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RHLEQTVASRTAELADANEQLQRELVERQRAEEQLQRYSGELRDINDELKSFAYMVSHDL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
RAPLINIKGFASELDLALKDAFPLLEQSLTTLSGKEREQVRFALQQDAPEALGFISSSVN
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
RMDALINAVLQLSYIGRREIRLETVCVTTIVNSILQSLRHQLEQRSVTVTVGELPEIIID
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
KMALEQIIGNLLDNAVKYLAPERPGRIEVNAYEEADGTTLRISDNGRGIAPGDMGKVFEL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHH
FRRGNCPDTVGEGMGLAYVKTLVRRFGGRIECESIPGVGTTFSVFIPIQSYSGKEYQ
HHCCCCCCHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]