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The map label for this gene is galE [H]

Identifier: 78222548

GI number: 78222548

Start: 1493177

End: 1494193

Strand: Direct

Name: galE [H]

Synonym: Gmet_1335

Alternate gene names: 78222548

Gene position: 1493177-1494193 (Clockwise)

Preceding gene: 78222547

Following gene: 78222549

Centisome position: 37.35

GC content: 51.52

Gene sequence:

>1017_bases
ATGCAACCAAATACCTATTTTCTGCATAACATCCTCGTTACCGGCGCAACCGGCTTTGTAGGTAGTTTTCTCTGCTCGCG
TCTGCTTGCCGAAGGGATGTCTGTCCGTGGAACCTTTCTAGTTACTGAAAATCCCGATTCTCTTGTCAAGGGCACTGAAC
AGGCATTGATCGAACCAATTGGGCCTGCCACATTCTGGGGCCATGCGCTTGCTGGTGCTGGCACGGTTATCCACCTGGCG
GCTCGTGTGCATGTGATGCGGGAGCGTGCTGCTGATCCGTTGAAAGAGTTCCGGTTTGTAAATACAGAGGGGACTGCACA
CCTTGCACGGGAAGCTGCCAAAGCCGGCGTCAAACGTTTCGTCTTTATGGGCACGATAGGTGTCAATGGCGACAACTCGG
GAGATGCCCCTTACATTGAATCCAGCCCGCCATATCCCCACAACCCTTATTCTGTTTCGAAATATGAAGCCGAACAACTG
TTGCGGCAGATATCTTCCGAGACAGGCATGGAGGTTGTGATAATCCGTGCACCCCTCGTCTATGGGCCGGGAAATCCTGG
TAATTTCCTCTCTCTGCTGAAGGCTGTCAACGGCGATTATGGATTCAAAACTTTGAATTTTGGATTGAAAGTCTTACCCC
TCCCACTTGCCTCAATCAATAACAAACGTAGCCTGATCTATGTCGGCAACCTTGTTGATGCACTGGTAACTTGCGCAACA
CATCCTGCCGCAGTTGGGCAGACATACCTCGTCAGTGATGGTGAAGATGTTTCTACTCCCGAACTTATCCGTCGTACGGC
CGCGGCTCTTGGGGTGCCGGCACGACTGTTCCCATTCCCAGTTCCTCTTATGAAGCTTGCTGGTAAACTGATTGACAAGA
GTGCTGCGGTCAATCGGCTGACCGGTTCTCTGACTGTTGATAGCTCCAAAATCAGGCGGGAGCTTGGCTGGCAACCGCCG
TTTACCATGGAAGAGGGATTGCAGGAGACTGCAAAATGGTTCGAAAAGCAAGGTTGA

Upstream 100 bases:

>100_bases
TAATGTCTTTGCATTCCGTAGGTCGTTTCGGGATCGAATAGCATTATTTTTTTTACTATTGTTGCCGCAGAAAAAATAGC
TTTACCGCGGAATATTCAAC

Downstream 100 bases:

>100_bases
ATTTTGGATGTCGAATTCTGGATGACTGGCAAAAGAGCAGATTTGGCATGTTTTATCCTTGCAAATCATGGAGTGATATT
CCAAAATTACAAATATGATA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQPNTYFLHNILVTGATGFVGSFLCSRLLAEGMSVRGTFLVTENPDSLVKGTEQALIEPIGPATFWGHALAGAGTVIHLA
ARVHVMRERAADPLKEFRFVNTEGTAHLAREAAKAGVKRFVFMGTIGVNGDNSGDAPYIESSPPYPHNPYSVSKYEAEQL
LRQISSETGMEVVIIRAPLVYGPGNPGNFLSLLKAVNGDYGFKTLNFGLKVLPLPLASINNKRSLIYVGNLVDALVTCAT
HPAAVGQTYLVSDGEDVSTPELIRRTAAALGVPARLFPFPVPLMKLAGKLIDKSAAVNRLTGSLTVDSSKIRRELGWQPP
FTMEEGLQETAKWFEKQG

Sequences:

>Translated_338_residues
MQPNTYFLHNILVTGATGFVGSFLCSRLLAEGMSVRGTFLVTENPDSLVKGTEQALIEPIGPATFWGHALAGAGTVIHLA
ARVHVMRERAADPLKEFRFVNTEGTAHLAREAAKAGVKRFVFMGTIGVNGDNSGDAPYIESSPPYPHNPYSVSKYEAEQL
LRQISSETGMEVVIIRAPLVYGPGNPGNFLSLLKAVNGDYGFKTLNFGLKVLPLPLASINNKRSLIYVGNLVDALVTCAT
HPAAVGQTYLVSDGEDVSTPELIRRTAAALGVPARLFPFPVPLMKLAGKLIDKSAAVNRLTGSLTVDSSKIRRELGWQPP
FTMEEGLQETAKWFEKQG
>Mature_338_residues
MQPNTYFLHNILVTGATGFVGSFLCSRLLAEGMSVRGTFLVTENPDSLVKGTEQALIEPIGPATFWGHALAGAGTVIHLA
ARVHVMRERAADPLKEFRFVNTEGTAHLAREAAKAGVKRFVFMGTIGVNGDNSGDAPYIESSPPYPHNPYSVSKYEAEQL
LRQISSETGMEVVIIRAPLVYGPGNPGNFLSLLKAVNGDYGFKTLNFGLKVLPLPLASINNKRSLIYVGNLVDALVTCAT
HPAAVGQTYLVSDGEDVSTPELIRRTAAALGVPARLFPFPVPLMKLAGKLIDKSAAVNRLTGSLTVDSSKIRRELGWQPP
FTMEEGLQETAKWFEKQG

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=356, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI48994969, Length=351, Percent_Identity=28.4900284900285, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081792, Length=355, Percent_Identity=23.0985915492958, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788353, Length=354, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786974, Length=360, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36450; Mature: 36450

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPNTYFLHNILVTGATGFVGSFLCSRLLAEGMSVRGTFLVTENPDSLVKGTEQALIEPI
CCCCCEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCHHHHHCCC
GPATFWGHALAGAGTVIHLAARVHVMRERAADPLKEFRFVNTEGTAHLAREAAKAGVKRF
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCEECCCCCHHHHHHHHHHHHHHHE
VFMGTIGVNGDNSGDAPYIESSPPYPHNPYSVSKYEAEQLLRQISSETGMEVVIIRAPLV
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECEE
YGPGNPGNFLSLLKAVNGDYGFKTLNFGLKVLPLPLASINNKRSLIYVGNLVDALVTCAT
ECCCCCHHHHHHHHHHCCCCCCEECCCCCEEEECCHHCCCCCCEEEEEHHHHHHHHHHCC
HPAAVGQTYLVSDGEDVSTPELIRRTAAALGVPARLFPFPVPLMKLAGKLIDKSAAVNRL
CCHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
TGSLTVDSSKIRRELGWQPPFTMEEGLQETAKWFEKQG
CCCEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQPNTYFLHNILVTGATGFVGSFLCSRLLAEGMSVRGTFLVTENPDSLVKGTEQALIEPI
CCCCCEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCHHHHHCCC
GPATFWGHALAGAGTVIHLAARVHVMRERAADPLKEFRFVNTEGTAHLAREAAKAGVKRF
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCEECCCCCHHHHHHHHHHHHHHHE
VFMGTIGVNGDNSGDAPYIESSPPYPHNPYSVSKYEAEQLLRQISSETGMEVVIIRAPLV
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECEE
YGPGNPGNFLSLLKAVNGDYGFKTLNFGLKVLPLPLASINNKRSLIYVGNLVDALVTCAT
ECCCCCHHHHHHHHHHCCCCCCEECCCCCEEEECCHHCCCCCCEEEEEHHHHHHHHHHCC
HPAAVGQTYLVSDGEDVSTPELIRRTAAALGVPARLFPFPVPLMKLAGKLIDKSAAVNRL
CCHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
TGSLTVDSSKIRRELGWQPPFTMEEGLQETAKWFEKQG
CCCEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]