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The map label for this gene is zraS [C]

Identifier: 78222457

GI number: 78222457

Start: 1400215

End: 1402179

Strand: Reverse

Name: zraS [C]

Synonym: Gmet_1243

Alternate gene names: 78222457

Gene position: 1402179-1400215 (Counterclockwise)

Preceding gene: 78222458

Following gene: 78222446

Centisome position: 35.08

GC content: 56.23

Gene sequence:

>1965_bases
ATGGATTTTTTCGACGAGCTGAAAAACCGTCGTGACAGCGTGGGACTGAGGTTCTTCCTCCTGTTCACACTCTTTATCGC
GGTAATTTCGATTTCGTTTACGGTTTTCTTCTTCCAGCAACAGCGAAGCGCCCTGAGGGATAGTCTGGTCAACGAGGGGA
AACTCCTGGCGAGACTCCTGGCCCACAATACCCGTCTCGGTGTTTTTGCCGAAAATGCAGAACTTCTGCGGGACCCCATC
CAGGGTATTCTGGAACACGAAGGAGTCCTTTTTGTCACCATCGTGACGGCAGAAGGTAAAGCACTCCAGGAACAGGCACA
CAAGAGTGTTATCAACAATTCCGGCCGGGCCTTTCCCCATTGGAGCACCCGCTTCGAACGGCTGAAAGGGACAACCGAGC
CCTCGGTCTTCGAGGGAGATGACATCTTCGAGTTCTGGGCACCAGTACTGTCGAGTTCATCCTTCCCCACGGACGGATCA
TTGTTCCTCGACCAACCCCCACGGCCAACGCCCCGCGTTATCGGTTATGCGCGAATCATCGTCGACAAGAGCCTTCTCGG
GAAAAAACTCGACACGCTCCTCTACACAAGCGTCCTCATGGCAGCGGGCTTTCTCCTCCTCGGCACCTTCTTCACCTACG
TCATAACCCGTAGAATTACGCGCCCCCTCGACCGACTCACCGAAGGGATCAGGGTTCTCGAAAGTTCTGGTTCATTCGAG
CCTGTCCCCGTGGAATCGAAGGATGAGATCGGCCGGCTCGCCACGGCGTTCAACCACCTGGGCACTACACTGAAAACCCG
TGAGGCCGAGAAGGAACTCCTGGCCGAGGAACTCCGCCATGCCCAGAAGATGGAGGCTATCGGAACACTTGCCGGGGGGG
TAGCCCACGATTTCAACAACATACTCACTGCCATCGTTGGCTTCGGAACGCTTCTGCAGCGCAGCCTCAAGACTGACAAC
CCCTATCGCATTTACGTGGAACAGATTCTCTCAGCCGCTGACCGGGCCACCAACCTCGTCAAACGGCTCCTCGCCTTCGG
CAGGAAGCAGGTAATCTCTCCTCACCCGACGAATCTGAATGACATTGTGAAGGGTATAGAGAAACTTCTCCATCGACTGG
TGAGCGAGGATATCACCTTTGTAACCTCGCTCTCCAGCGAACCCCTCGTGTGCCATGTGGATGCGGGGCAAATCGACCAG
ATCCTGATGAATCTCGTGACAAACGCCCGCGACGCCATGCCGGACGGCGGCACGCTTACTGTTACGACGGGGAGCGACTT
CCTGGAAGAAGATTTCTTCGGTCCCCTTGAAAAGGGAAAAACCGGCTACTACGCAATTCTGACCATTGCAGATTCGGGCA
CCGGCATGGACTGCGAAACACAGGAACGCATCTTCGACCCCTTCTTCACCACCAAGGAGGTCGGCAAGGGAACAGGGCTC
GGCCTCTCCATGGTCTACGGCATCGTCAAGCAGCACGAGGGATTCATCACCGTTGATTCAGAGATAGGGAAAGGAACTGC
CGTCAGAATTTACCTTCCCATCGTGGCGCCAAAGGAGACCACGGAGCACCGCGACGCAACGGCGGCCGCCCAGGGGAACC
AGGAGACCATCCTGATAGCCGAAGACGACCGGGACGTGCGCAAGCTCTCGAAGCTCGTTCTTGAACGCAACGGCTACACC
GTCATCGAAGCGAGCGACGGTGCCGAGGCTGTCCGGCGGTTCATGGAGAACAGCACCCGGATAGACCTTCTGCTTCTCGA
TGTGGTTATGCCCAAAAGGAACGGCCAGTCCGTCTATGAAGAGATCCGGAACATCCGGCCGGAGATGAAGGCGCTCTTCA
TCAGCGGCTACACCCAGGACATCATCAGCCGGAAAGGGGTCCTCGACGAGGGGATCAACTTCATAGCGAAACCGGTGAAA
CCGGACGAACTCCTGGCAAAGATCAAAGAGGTATTACAGAACTGA

Upstream 100 bases:

>100_bases
GCGCGGTCATCACGATAAACAGCAGGATAGCGCGCAAACTTGGCCTCTCCTTGAACGAAGAGGCTTTAAGTCGAGCCAAA
GTCATACGCTAGGGGAAAGA

Downstream 100 bases:

>100_bases
AAAAGCCCGCGGAAGCGGGCTTTTCTTTACGATGCAGCACAGTGGTGCCGGCAGGTGTCGCTACTTTTTTGCCTCGAAGA
GGGTTACCTTCCCGTCGTCA

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MDFFDELKNRRDSVGLRFFLLFTLFIAVISISFTVFFFQQQRSALRDSLVNEGKLLARLLAHNTRLGVFAENAELLRDPI
QGILEHEGVLFVTIVTAEGKALQEQAHKSVINNSGRAFPHWSTRFERLKGTTEPSVFEGDDIFEFWAPVLSSSSFPTDGS
LFLDQPPRPTPRVIGYARIIVDKSLLGKKLDTLLYTSVLMAAGFLLLGTFFTYVITRRITRPLDRLTEGIRVLESSGSFE
PVPVESKDEIGRLATAFNHLGTTLKTREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLKTDN
PYRIYVEQILSAADRATNLVKRLLAFGRKQVISPHPTNLNDIVKGIEKLLHRLVSEDITFVTSLSSEPLVCHVDAGQIDQ
ILMNLVTNARDAMPDGGTLTVTTGSDFLEEDFFGPLEKGKTGYYAILTIADSGTGMDCETQERIFDPFFTTKEVGKGTGL
GLSMVYGIVKQHEGFITVDSEIGKGTAVRIYLPIVAPKETTEHRDATAAAQGNQETILIAEDDRDVRKLSKLVLERNGYT
VIEASDGAEAVRRFMENSTRIDLLLLDVVMPKRNGQSVYEEIRNIRPEMKALFISGYTQDIISRKGVLDEGINFIAKPVK
PDELLAKIKEVLQN

Sequences:

>Translated_654_residues
MDFFDELKNRRDSVGLRFFLLFTLFIAVISISFTVFFFQQQRSALRDSLVNEGKLLARLLAHNTRLGVFAENAELLRDPI
QGILEHEGVLFVTIVTAEGKALQEQAHKSVINNSGRAFPHWSTRFERLKGTTEPSVFEGDDIFEFWAPVLSSSSFPTDGS
LFLDQPPRPTPRVIGYARIIVDKSLLGKKLDTLLYTSVLMAAGFLLLGTFFTYVITRRITRPLDRLTEGIRVLESSGSFE
PVPVESKDEIGRLATAFNHLGTTLKTREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLKTDN
PYRIYVEQILSAADRATNLVKRLLAFGRKQVISPHPTNLNDIVKGIEKLLHRLVSEDITFVTSLSSEPLVCHVDAGQIDQ
ILMNLVTNARDAMPDGGTLTVTTGSDFLEEDFFGPLEKGKTGYYAILTIADSGTGMDCETQERIFDPFFTTKEVGKGTGL
GLSMVYGIVKQHEGFITVDSEIGKGTAVRIYLPIVAPKETTEHRDATAAAQGNQETILIAEDDRDVRKLSKLVLERNGYT
VIEASDGAEAVRRFMENSTRIDLLLLDVVMPKRNGQSVYEEIRNIRPEMKALFISGYTQDIISRKGVLDEGINFIAKPVK
PDELLAKIKEVLQN
>Mature_654_residues
MDFFDELKNRRDSVGLRFFLLFTLFIAVISISFTVFFFQQQRSALRDSLVNEGKLLARLLAHNTRLGVFAENAELLRDPI
QGILEHEGVLFVTIVTAEGKALQEQAHKSVINNSGRAFPHWSTRFERLKGTTEPSVFEGDDIFEFWAPVLSSSSFPTDGS
LFLDQPPRPTPRVIGYARIIVDKSLLGKKLDTLLYTSVLMAAGFLLLGTFFTYVITRRITRPLDRLTEGIRVLESSGSFE
PVPVESKDEIGRLATAFNHLGTTLKTREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLKTDN
PYRIYVEQILSAADRATNLVKRLLAFGRKQVISPHPTNLNDIVKGIEKLLHRLVSEDITFVTSLSSEPLVCHVDAGQIDQ
ILMNLVTNARDAMPDGGTLTVTTGSDFLEEDFFGPLEKGKTGYYAILTIADSGTGMDCETQERIFDPFFTTKEVGKGTGL
GLSMVYGIVKQHEGFITVDSEIGKGTAVRIYLPIVAPKETTEHRDATAAAQGNQETILIAEDDRDVRKLSKLVLERNGYT
VIEASDGAEAVRRFMENSTRIDLLLLDVVMPKRNGQSVYEEIRNIRPEMKALFISGYTQDIISRKGVLDEGINFIAKPVK
PDELLAKIKEVLQN

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=30.2521008403361, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=30.6451612903226, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=288, Percent_Identity=28.4722222222222, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=493, Percent_Identity=23.7322515212982, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=379, Percent_Identity=24.5382585751979, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72733; Mature: 72733

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFFDELKNRRDSVGLRFFLLFTLFIAVISISFTVFFFQQQRSALRDSLVNEGKLLARLL
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AHNTRLGVFAENAELLRDPIQGILEHEGVLFVTIVTAEGKALQEQAHKSVINNSGRAFPH
HCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
WSTRFERLKGTTEPSVFEGDDIFEFWAPVLSSSSFPTDGSLFLDQPPRPTPRVIGYARII
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHH
VDKSLLGKKLDTLLYTSVLMAAGFLLLGTFFTYVITRRITRPLDRLTEGIRVLESSGSFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVPVESKDEIGRLATAFNHLGTTLKTREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNN
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTAIVGFGTLLQRSLKTDNPYRIYVEQILSAADRATNLVKRLLAFGRKQVISPHPTNLN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHH
DIVKGIEKLLHRLVSEDITFVTSLSSEPLVCHVDAGQIDQILMNLVTNARDAMPDGGTLT
HHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEE
VTTGSDFLEEDFFGPLEKGKTGYYAILTIADSGTGMDCETQERIFDPFFTTKEVGKGTGL
EECCCHHHHHHCCCCHHCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHCCCCCC
GLSMVYGIVKQHEGFITVDSEIGKGTAVRIYLPIVAPKETTEHRDATAAAQGNQETILIA
HHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCEEEEE
EDDRDVRKLSKLVLERNGYTVIEASDGAEAVRRFMENSTRIDLLLLDVVMPKRNGQSVYE
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEEHHCCCCCCHHHHH
EIRNIRPEMKALFISGYTQDIISRKGVLDEGINFIAKPVKPDELLAKIKEVLQN
HHHHCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFFDELKNRRDSVGLRFFLLFTLFIAVISISFTVFFFQQQRSALRDSLVNEGKLLARLL
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AHNTRLGVFAENAELLRDPIQGILEHEGVLFVTIVTAEGKALQEQAHKSVINNSGRAFPH
HCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
WSTRFERLKGTTEPSVFEGDDIFEFWAPVLSSSSFPTDGSLFLDQPPRPTPRVIGYARII
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHH
VDKSLLGKKLDTLLYTSVLMAAGFLLLGTFFTYVITRRITRPLDRLTEGIRVLESSGSFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVPVESKDEIGRLATAFNHLGTTLKTREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNN
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTAIVGFGTLLQRSLKTDNPYRIYVEQILSAADRATNLVKRLLAFGRKQVISPHPTNLN
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHH
DIVKGIEKLLHRLVSEDITFVTSLSSEPLVCHVDAGQIDQILMNLVTNARDAMPDGGTLT
HHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEE
VTTGSDFLEEDFFGPLEKGKTGYYAILTIADSGTGMDCETQERIFDPFFTTKEVGKGTGL
EECCCHHHHHHCCCCHHCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHCCCCCC
GLSMVYGIVKQHEGFITVDSEIGKGTAVRIYLPIVAPKETTEHRDATAAAQGNQETILIA
HHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCEEEEE
EDDRDVRKLSKLVLERNGYTVIEASDGAEAVRRFMENSTRIDLLLLDVVMPKRNGQSVYE
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEEHHCCCCCCHHHHH
EIRNIRPEMKALFISGYTQDIISRKGVLDEGINFIAKPVKPDELLAKIKEVLQN
HHHHCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA