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The map label for this gene is ygbD [C]

Identifier: 78222364

GI number: 78222364

Start: 1274295

End: 1275650

Strand: Reverse

Name: ygbD [C]

Synonym: Gmet_1148

Alternate gene names: 78222364

Gene position: 1275650-1274295 (Counterclockwise)

Preceding gene: 78222365

Following gene: 78222343

Centisome position: 31.91

GC content: 63.72

Gene sequence:

>1356_bases
ATGGCCAAGGAAAAACTCGTTGTCATCGGCGGAGATGCCGCGGGGATGAGCGCCGCATCCCAGGCGAAGCGCCGCCGGCC
CGAACTGGAGATCGTCGTTTTCGAGCGAAGCCCCCACACGTCCTTTTCCGCGTGAGGGATTCCCTACTACGTCGGCCGGG
TTGTCGACAAGGAAGAAAAGCTCGTTATCCGTTCCCCGGAAAAGTTCCGGGAGAAATATGGAATCGATGCAAGGGCCCTG
CATGAGGTAGTGGAAATCGACGCGGCACAGGGAAAGGTGCGGGTGCGCGATCTGCAGCGCGGCGGGTCGGCGTGGGAGTC
CTACGACCAGCTTCTGATCGCCACCGGCGCGGTCCCCCTCTGCCCGGACCTTCCCGGCTCCGATGCCGTTGACATCTGCG
GGGTGAACACCCTTGAAAGTGGCCTGGAGATCCGCAGGCGTCTCGACAAGGGGGGGATGAAAAAGGGAGTTGTCGTCGGG
GGCGGGTACATCGGCCTGGAGATGGCGGAAGCGTTGGTACGGCATGGCCTTGAGGTTTCCCTCGTCAACAGGGCACCGCA
GGTCATGGGAACCCTCGACTACGACATGGGGGCCATGGTCTCACAGGCCCTGCGCGATGTGGGGGTCAGCCTTTATCTGG
AGGAGACTCTCACCGCGTTCGAGACAAAGGGGGGGAAAGTGACCGGGGTGGTCACGGACAGGCGCACCCTGCCGGCTGAC
ATCGTGATCCTCGGCCTGGGGGTGCGCCCTAACACGGCCCTTGCCTCGGCTGCCGGCATCCCCCTCGGGGAGAAGGGGTC
GATCAGGGTGAACGAACGGATGCAGACCGGCGTTGCCGGTATCTGGGCGGCAGGGGATTGCGCCGAATCGTTCCATCTGG
TGAGCCGCAAACCCGTCCATATCGCCCTCGGCACCGTCGCCAACCGGCACGGAAGGGTCGCGGGGATCAACCTGGGGGGC
GGCTATGCCACGTTTCCCGGGGTCGTGGGGACAGCGGTCACAAAAATATGCCAGGTGGAGGTCGCACGGACCGGCCTCCA
GGAAGAGGAACTCAGGGAACTGGGGATTGAGTGGATCAGCGCCGTCATTAAGAGCCGCACCAGGGCCGGCTACTTTCCCG
GCGCAGGGGGAATAACCGTAAAGGTGTTGGCGGAACGGGGGAGCGGCCGCCTGCTGGGAGGGCAGATCGTCGGGATGGAA
GGCTCGGCCAAGCGGATAGATACCCTGGCGACCGCCCTTCATGCCGGTTTTACGGTGGAGGAGATGATCAACCTGGACCT
GGGCTATGCCCCCCCGTTCTCACCGGTCTGGGACCCGGTCGTAATCGCTGCCCGTGAGGTTGCAAAGGAACTTTAG

Upstream 100 bases:

>100_bases
TGCCGCATGACTGCAGTTTCCCATTTCATAGGGATTGATCAATTTCAGTTCCACACAGGTCTTGCCATCAAACTGTATTG
ATCTGGAGAGGATACGAATC

Downstream 100 bases:

>100_bases
GAGGAATCGGGGTCGCCGCCTCAAGGAAGGGGGGCCATGCCGATGCCAGACCCGATGGAGAGATCAGTCAATGGGCCATA
GGAAGCTATCCTCCGGGGCA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MAKEKLVVIGGDAAGMSAASQAKRRRPELEIVVFERSPHTSFSAUGIPYYVGRVVDKEEKLVIRSPEKFREKYGIDARAL
HEVVEIDAAQGKVRVRDLQRGGSAWESYDQLLIATGAVPLCPDLPGSDAVDICGVNTLESGLEIRRRLDKGGMKKGVVVG
GGYIGLEMAEALVRHGLEVSLVNRAPQVMGTLDYDMGAMVSQALRDVGVSLYLEETLTAFETKGGKVTGVVTDRRTLPAD
IVILGLGVRPNTALASAAGIPLGEKGSIRVNERMQTGVAGIWAAGDCAESFHLVSRKPVHIALGTVANRHGRVAGINLGG
GYATFPGVVGTAVTKICQVEVARTGLQEEELRELGIEWISAVIKSRTRAGYFPGAGGITVKVLAERGSGRLLGGQIVGME
GSAKRIDTLATALHAGFTVEEMINLDLGYAPPFSPVWDPVVIAAREVAKEL

Sequences:

>Translated_451_residues
MAKEKLVVIGGDAAGMSAASQAKRRRPELEIVVFERSPHTSFSA*GIPYYVGRVVDKEEKLVIRSPEKFREKYGIDARAL
HEVVEIDAAQGKVRVRDLQRGGSAWESYDQLLIATGAVPLCPDLPGSDAVDICGVNTLESGLEIRRRLDKGGMKKGVVVG
GGYIGLEMAEALVRHGLEVSLVNRAPQVMGTLDYDMGAMVSQALRDVGVSLYLEETLTAFETKGGKVTGVVTDRRTLPAD
IVILGLGVRPNTALASAAGIPLGEKGSIRVNERMQTGVAGIWAAGDCAESFHLVSRKPVHIALGTVANRHGRVAGINLGG
GYATFPGVVGTAVTKICQVEVARTGLQEEELRELGIEWISAVIKSRTRAGYFPGAGGITVKVLAERGSGRLLGGQIVGME
GSAKRIDTLATALHAGFTVEEMINLDLGYAPPFSPVWDPVVIAAREVAKEL
>Mature_450_residues
AKEKLVVIGGDAAGMSAASQAKRRRPELEIVVFERSPHTSFSA*GIPYYVGRVVDKEEKLVIRSPEKFREKYGIDARALH
EVVEIDAAQGKVRVRDLQRGGSAWESYDQLLIATGAVPLCPDLPGSDAVDICGVNTLESGLEIRRRLDKGGMKKGVVVGG
GYIGLEMAEALVRHGLEVSLVNRAPQVMGTLDYDMGAMVSQALRDVGVSLYLEETLTAFETKGGKVTGVVTDRRTLPADI
VILGLGVRPNTALASAAGIPLGEKGSIRVNERMQTGVAGIWAAGDCAESFHLVSRKPVHIALGTVANRHGRVAGINLGGG
YATFPGVVGTAVTKICQVEVARTGLQEEELRELGIEWISAVIKSRTRAGYFPGAGGITVKVLAERGSGRLLGGQIVGMEG
SAKRIDTLATALHAGFTVEEMINLDLGYAPPFSPVWDPVVIAAREVAKEL

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=317, Percent_Identity=28.7066246056782, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI65787454, Length=317, Percent_Identity=28.7066246056782, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21389617, Length=317, Percent_Identity=28.7066246056782, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI91199540, Length=293, Percent_Identity=26.962457337884, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789065, Length=234, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786307, Length=306, Percent_Identity=29.7385620915033, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789765, Length=293, Percent_Identity=28.3276450511945, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559934, Length=265, Percent_Identity=27.5471698113208, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=262, Percent_Identity=29.7709923664122, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639257, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281359715, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281359713, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639250, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI18543267, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639252, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24585130, Length=291, Percent_Identity=24.7422680412371, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358499, Length=279, Percent_Identity=28.3154121863799, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47738; Mature: 47606

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKLVVIGGDAAGMSAASQAKRRRPELEIVVFERSPHTSFSAGIPYYVGRVVDKEEKL
CCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCE
VIRSPEKFREKYGIDARALHEVVEIDAAQGKVRVRDLQRGGSAWESYDQLLIATGAVPLC
EEECCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHCCCCHHHHHHHEEEECCCCCCC
PDLPGSDAVDICGVNTLESGLEIRRRLDKGGMKKGVVVGGGYIGLEMAEALVRHGLEVSL
CCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEE
VNRAPQVMGTLDYDMGAMVSQALRDVGVSLYLEETLTAFETKGGKVTGVVTDRRTLPADI
ECCCCHHHEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCEEEEEEECCCCCCCEE
VILGLGVRPNTALASAAGIPLGEKGSIRVNERMQTGVAGIWAAGDCAESFHLVSRKPVHI
EEEECCCCCCHHHHHHCCCCCCCCCCEEECHHHHCCCCEEEECCHHHHHHHHHCCCCEEE
ALGTVANRHGRVAGINLGGGYATFPGVVGTAVTKICQVEVARTGLQEEELRELGIEWISA
EEECHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIKSRTRAGYFPGAGGITVKVLAERGSGRLLGGQIVGMEGSAKRIDTLATALHAGFTVEE
HHHHHHCCCCCCCCCCEEEEEEEECCCCEEECCEEECCCCCHHHHHHHHHHHHCCCCHHH
MINLDLGYAPPFSPVWDPVVIAAREVAKEL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AKEKLVVIGGDAAGMSAASQAKRRRPELEIVVFERSPHTSFSAGIPYYVGRVVDKEEKL
CCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCE
VIRSPEKFREKYGIDARALHEVVEIDAAQGKVRVRDLQRGGSAWESYDQLLIATGAVPLC
EEECCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHCCCCHHHHHHHEEEECCCCCCC
PDLPGSDAVDICGVNTLESGLEIRRRLDKGGMKKGVVVGGGYIGLEMAEALVRHGLEVSL
CCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEE
VNRAPQVMGTLDYDMGAMVSQALRDVGVSLYLEETLTAFETKGGKVTGVVTDRRTLPADI
ECCCCHHHEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCEEEEEEECCCCCCCEE
VILGLGVRPNTALASAAGIPLGEKGSIRVNERMQTGVAGIWAAGDCAESFHLVSRKPVHI
EEEECCCCCCHHHHHHCCCCCCCCCCEEECHHHHCCCCEEEECCHHHHHHHHHCCCCEEE
ALGTVANRHGRVAGINLGGGYATFPGVVGTAVTKICQVEVARTGLQEEELRELGIEWISA
EEECHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIKSRTRAGYFPGAGGITVKVLAERGSGRLLGGQIVGMEGSAKRIDTLATALHAGFTVEE
HHHHHHCCCCCCCCCCEEEEEEEECCCCEEECCEEECCCCCHHHHHHHHHHHHCCCCHHH
MINLDLGYAPPFSPVWDPVVIAAREVAKEL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA