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The map label for this gene is resD [H]

Identifier: 78222175

GI number: 78222175

Start: 1061055

End: 1062374

Strand: Direct

Name: resD [H]

Synonym: Gmet_0955

Alternate gene names: 78222175

Gene position: 1061055-1062374 (Clockwise)

Preceding gene: 78222174

Following gene: 78222176

Centisome position: 26.54

GC content: 62.05

Gene sequence:

>1320_bases
ATGGGCAACAGGATTCTCCTTGCCGACGACAGCATCACAATCCAGAAGGTCGTGGGGATCATCTTCGCCAACGAGGACTG
CGACCTTACTGTCGTTGACAATGGGGACTCCGCTGTGGAGAAGGCCCGCGAAGTCACCCCTGATGTGATGCTGGTGGACG
CCCTCATGCCCGGCAAGTCCGGCTACGAGGTCTGTACCGCCATCCGGAAGGATCCCGCCCTCGGCACTGTCCCCATCCTC
CTCATGACCGGTGCCTTCGAGCCCTTTGACGAGGAGAAGGCCCGCCAGTGCGGCGCCGACGATTTCATCTCCAAGCCTTT
CGAGTCCCAGCAACTTATCGACAAGGTCAAAACTCTCCTTGATCTTGGCAAAAGCCGGGCCGGGGCGCCGTCAGTGGCGG
CAGCAGCACCGACTATGACGGCCGTGACGCCGCCTGCGGCGCCGACAGTGGCAGAGGCGGCTGAATCAATTGCGTCCGTT
GCACCAGTTGCTGCCGGGCCGGTTGAGTCCTTTGCCATTGAATTCGACGAACCCGCGTCCAGTGAGCCCCAGCCGGCCGT
GACGCCACCTCCCACCCCCGAACCCACGGCCGCCAAGGTAACCGTGCCCGAACCGCAACCCTTTGTCTTCGCGGTTGAGG
AGGCATCTCCCGCCGATGATCTCTGGGGTGCTTTCGAGCTTGAGGACGAGGTTGTCGGTGACGAGCCTGTCAAGTCCAGC
CAGGCGGCTGCCGATGGAGCGTCCGCCGCAGTAGACGAGGTTTCTCCCTTTGGGCTGGAACAGACTCCGGACGTCTTTGG
TGCCGGAACGGGGCCTGCCGCCGAGTCGGTCGATTTCGGCTTTGCCTCTGCCAGCGACGAGTTCGGTTTTGCCGTGGCGG
CGGAAACGCCTGCTCCGTCAGCTTCCGTCGAACCGGCACCCTTCAGTGCTCCCCCCATGGATGAGTCATTCGTATTCGGC
GAGGAGAGCGCTGAAAGCGTTGTTGAGCCGTACGGAAGCATTTCCGAAACGCCGGTTTCCGGAGCGTTTGACCCGGGCAT
CGAGCCCTTTGAAATGCCCTTGAAAACGGAATTTACTCCGGCCGCCGGGGTATCTTCATTTGCTCCTGAAGAGAAACCGG
TTCCGTCATCCGCGTCCTTCACTGCTGCGCCCGCTGTCGAGGGGGGTGGAGGGACCATCACCCTGACCGAGGAGCAGCTT
GCTGCAGCCATCTCCCGCATTTCCCGGGAGGTCATCGAGCGGATCGCGTGGGAAGTGGTGCCCGATCTGGCCGAAACCCT
CATCAAGGAAGAGATCCGCCGGATCAAGGAAGGCAGTTAG

Upstream 100 bases:

>100_bases
GGTAAACATCTTGACACCCACCGGGGGGCTGTGCTAGTTTTTCCGCGGTTGTTCGCGGTTTTTCAGGACTTACGGCGCTC
CTATCCGAGGAGGTTTTTTC

Downstream 100 bases:

>100_bases
GAACCGGGGACCGGGGGGCAGGGACCGGCAGGAATTGTTGCGCTGAAATGGGGATGACACATCCCCATTTTTCATTTTGC
AGATGAAAGAGGTTATCCCA

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MGNRILLADDSITIQKVVGIIFANEDCDLTVVDNGDSAVEKAREVTPDVMLVDALMPGKSGYEVCTAIRKDPALGTVPIL
LMTGAFEPFDEEKARQCGADDFISKPFESQQLIDKVKTLLDLGKSRAGAPSVAAAAPTMTAVTPPAAPTVAEAAESIASV
APVAAGPVESFAIEFDEPASSEPQPAVTPPPTPEPTAAKVTVPEPQPFVFAVEEASPADDLWGAFELEDEVVGDEPVKSS
QAAADGASAAVDEVSPFGLEQTPDVFGAGTGPAAESVDFGFASASDEFGFAVAAETPAPSASVEPAPFSAPPMDESFVFG
EESAESVVEPYGSISETPVSGAFDPGIEPFEMPLKTEFTPAAGVSSFAPEEKPVPSSASFTAAPAVEGGGGTITLTEEQL
AAAISRISREVIERIAWEVVPDLAETLIKEEIRRIKEGS

Sequences:

>Translated_439_residues
MGNRILLADDSITIQKVVGIIFANEDCDLTVVDNGDSAVEKAREVTPDVMLVDALMPGKSGYEVCTAIRKDPALGTVPIL
LMTGAFEPFDEEKARQCGADDFISKPFESQQLIDKVKTLLDLGKSRAGAPSVAAAAPTMTAVTPPAAPTVAEAAESIASV
APVAAGPVESFAIEFDEPASSEPQPAVTPPPTPEPTAAKVTVPEPQPFVFAVEEASPADDLWGAFELEDEVVGDEPVKSS
QAAADGASAAVDEVSPFGLEQTPDVFGAGTGPAAESVDFGFASASDEFGFAVAAETPAPSASVEPAPFSAPPMDESFVFG
EESAESVVEPYGSISETPVSGAFDPGIEPFEMPLKTEFTPAAGVSSFAPEEKPVPSSASFTAAPAVEGGGGTITLTEEQL
AAAISRISREVIERIAWEVVPDLAETLIKEEIRRIKEGS
>Mature_438_residues
GNRILLADDSITIQKVVGIIFANEDCDLTVVDNGDSAVEKAREVTPDVMLVDALMPGKSGYEVCTAIRKDPALGTVPILL
MTGAFEPFDEEKARQCGADDFISKPFESQQLIDKVKTLLDLGKSRAGAPSVAAAAPTMTAVTPPAAPTVAEAAESIASVA
PVAAGPVESFAIEFDEPASSEPQPAVTPPPTPEPTAAKVTVPEPQPFVFAVEEASPADDLWGAFELEDEVVGDEPVKSSQ
AAADGASAAVDEVSPFGLEQTPDVFGAGTGPAAESVDFGFASASDEFGFAVAAETPAPSASVEPAPFSAPPMDESFVFGE
ESAESVVEPYGSISETPVSGAFDPGIEPFEMPLKTEFTPAAGVSSFAPEEKPVPSSASFTAAPAVEGGGGTITLTEEQLA
AAISRISREVIERIAWEVVPDLAETLIKEEIRRIKEGS

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=95, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=32.4786324786325, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=28.6764705882353, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 45387; Mature: 45255

Theoretical pI: Translated: 3.73; Mature: 3.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRILLADDSITIQKVVGIIFANEDCDLTVVDNGDSAVEKAREVTPDVMLVDALMPGKS
CCCEEEEECCCEEHHHHHEHEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEEHHCCCCC
GYEVCTAIRKDPALGTVPILLMTGAFEPFDEEKARQCGADDFISKPFESQQLIDKVKTLL
CHHHHHHHHCCCCCCCHHHHHEECCCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
DLGKSRAGAPSVAAAAPTMTAVTPPAAPTVAEAAESIASVAPVAAGPVESFAIEFDEPAS
HHCCCCCCCCCHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCC
SEPQPAVTPPPTPEPTAAKVTVPEPQPFVFAVEEASPADDLWGAFELEDEVVGDEPVKSS
CCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHCCEEECCHHHCCCCCCCCH
QAAADGASAAVDEVSPFGLEQTPDVFGAGTGPAAESVDFGFASASDEFGFAVAAETPAPS
HHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
ASVEPAPFSAPPMDESFVFGEESAESVVEPYGSISETPVSGAFDPGIEPFEMPLKTEFTP
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAGVSSFAPEEKPVPSSASFTAAPAVEGGGGTITLTEEQLAAAISRISREVIERIAWEVV
CCCCHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
PDLAETLIKEEIRRIKEGS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GNRILLADDSITIQKVVGIIFANEDCDLTVVDNGDSAVEKAREVTPDVMLVDALMPGKS
CCEEEEECCCEEHHHHHEHEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEEHHCCCCC
GYEVCTAIRKDPALGTVPILLMTGAFEPFDEEKARQCGADDFISKPFESQQLIDKVKTLL
CHHHHHHHHCCCCCCCHHHHHEECCCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
DLGKSRAGAPSVAAAAPTMTAVTPPAAPTVAEAAESIASVAPVAAGPVESFAIEFDEPAS
HHCCCCCCCCCHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCC
SEPQPAVTPPPTPEPTAAKVTVPEPQPFVFAVEEASPADDLWGAFELEDEVVGDEPVKSS
CCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHCCEEECCHHHCCCCCCCCH
QAAADGASAAVDEVSPFGLEQTPDVFGAGTGPAAESVDFGFASASDEFGFAVAAETPAPS
HHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
ASVEPAPFSAPPMDESFVFGEESAESVVEPYGSISETPVSGAFDPGIEPFEMPLKTEFTP
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAGVSSFAPEEKPVPSSASFTAAPAVEGGGGTITLTEEQLAAAISRISREVIERIAWEVV
CCCCHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
PDLAETLIKEEIRRIKEGS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]