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The map label for this gene is mrdB [H]

Identifier: 78222149

GI number: 78222149

Start: 1023492

End: 1024592

Strand: Direct

Name: mrdB [H]

Synonym: Gmet_0929

Alternate gene names: 78222149

Gene position: 1023492-1024592 (Clockwise)

Preceding gene: 78222148

Following gene: 78222150

Centisome position: 25.6

GC content: 55.4

Gene sequence:

>1101_bases
ATGATCGATCGCAGACTTTTTACCAATTTCGACTGGACTCTCCTGGTGCTGGTGTTCCTCATCAGCGCCATGGGCATAGT
CAATATCTACAGTGCGTCCGCTTCCTATACCCTGGTGGGGGCACCCTATTACCTCAAGCAGTTCTACTGGATCGTTGCCG
GCATGTTCCTGGTGGTGCTCGCCTGCAGTGTCGACTACCATCTGCTGGAGGACGTTACCTACTGGTTTTACGGGTTACTC
TGCGTTGTGCTGGTTGCCGTCCTGCTGATGGGAAAGACATCCATGGGGGCCACTCGCTGGCTTCACCTCGGATTTTTCAG
CATCCAACCATCCGAACCGATGAAGGTGGTCATGATTATGACCCTCGCACGGTTCCTTTCACGGTACCCGGCCGTCGACG
GGTTAACCGTGCGGGATCTCGTCTATCCCCTGTTGTTCGTGGGGGGACCGGCAATCCTCATCATGAAGCAGCCCGACCTG
GGCACTGCCATTGTCATAATTCTCATTGCCTGTTCCATGATTGCCTATGTAGGAGTCCGCTTGGCAACCCTCGTCGCCTG
CCTTGCGGCAACCGTCCCCGCGATTTACCTGGGATGGCGCTATTACCTACGTGATTACCAGAAAAACAGAATCCTCAACT
TCCTCAATCCGGAACGCGATCCGCTCGGATCGGGCTACCATATCATCCAAAGCAAGATTGCAGTCGGTTCAGGGGGGATA
TTCGGCAAGGGGTTTACCCACGGGACCCAGACCCAGCTCCGTTTCCTCCCCGAACAGCACACCGATTTCGCATTCTCGGT
TTTCGGCGAGGAGTGGGGGTTCATCGGGTGTCTGACGCTGCTGCTTCTCTACCTGTTCCTCATTTTCTGGGGACTCCACA
TTGCCGGCAGGTGTAACGACCGATTCGGCAGCCTTATGGCCGTCGGGGTGACGGCCATGCTCTTCTGGCATACCATCATC
AATATCGGCATGGTAATCGGGGTATTCCCGGTTGTCGGCGTTCCCCTCCCGCTTTTCTCCTATGGCGGCACCTCAATGAT
CACCTCCATGATTGGTGTGGGAGTGCTGCTCAATATCAGCATGCGCAGGTTCATGTTCTAG

Upstream 100 bases:

>100_bases
CCGTCAGGAAAGATGTTCCCAGCGAGACGGGAGAGCAGGCAGGGCAGGAAACACCGGCATCCGAGCAAGGCGGCAGTGCG
TCGCAAGGACAGCAAGAGCA

Downstream 100 bases:

>100_bases
TACTCTCCTCCCGGTAGACAGCCCCTCAAGCCTCGCATGAATGCATCTCCTGAGACCGTCGGGAACGGCGCTTTGATCAG
TTTTCTGTTTGGGTCCGAAG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIDRRLFTNFDWTLLVLVFLISAMGIVNIYSASASYTLVGAPYYLKQFYWIVAGMFLVVLACSVDYHLLEDVTYWFYGLL
CVVLVAVLLMGKTSMGATRWLHLGFFSIQPSEPMKVVMIMTLARFLSRYPAVDGLTVRDLVYPLLFVGGPAILIMKQPDL
GTAIVIILIACSMIAYVGVRLATLVACLAATVPAIYLGWRYYLRDYQKNRILNFLNPERDPLGSGYHIIQSKIAVGSGGI
FGKGFTHGTQTQLRFLPEQHTDFAFSVFGEEWGFIGCLTLLLLYLFLIFWGLHIAGRCNDRFGSLMAVGVTAMLFWHTII
NIGMVIGVFPVVGVPLPLFSYGGTSMITSMIGVGVLLNISMRRFMF

Sequences:

>Translated_366_residues
MIDRRLFTNFDWTLLVLVFLISAMGIVNIYSASASYTLVGAPYYLKQFYWIVAGMFLVVLACSVDYHLLEDVTYWFYGLL
CVVLVAVLLMGKTSMGATRWLHLGFFSIQPSEPMKVVMIMTLARFLSRYPAVDGLTVRDLVYPLLFVGGPAILIMKQPDL
GTAIVIILIACSMIAYVGVRLATLVACLAATVPAIYLGWRYYLRDYQKNRILNFLNPERDPLGSGYHIIQSKIAVGSGGI
FGKGFTHGTQTQLRFLPEQHTDFAFSVFGEEWGFIGCLTLLLLYLFLIFWGLHIAGRCNDRFGSLMAVGVTAMLFWHTII
NIGMVIGVFPVVGVPLPLFSYGGTSMITSMIGVGVLLNISMRRFMF
>Mature_366_residues
MIDRRLFTNFDWTLLVLVFLISAMGIVNIYSASASYTLVGAPYYLKQFYWIVAGMFLVVLACSVDYHLLEDVTYWFYGLL
CVVLVAVLLMGKTSMGATRWLHLGFFSIQPSEPMKVVMIMTLARFLSRYPAVDGLTVRDLVYPLLFVGGPAILIMKQPDL
GTAIVIILIACSMIAYVGVRLATLVACLAATVPAIYLGWRYYLRDYQKNRILNFLNPERDPLGSGYHIIQSKIAVGSGGI
FGKGFTHGTQTQLRFLPEQHTDFAFSVFGEEWGFIGCLTLLLLYLFLIFWGLHIAGRCNDRFGSLMAVGVTAMLFWHTII
NIGMVIGVFPVVGVPLPLFSYGGTSMITSMIGVGVLLNISMRRFMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=345, Percent_Identity=42.3188405797101, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1786277, Length=358, Percent_Identity=29.608938547486, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40831; Mature: 40831

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRLFTNFDWTLLVLVFLISAMGIVNIYSASASYTLVGAPYYLKQFYWIVAGMFLVVL
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
ACSVDYHLLEDVTYWFYGLLCVVLVAVLLMGKTSMGATRWLHLGFFSIQPSEPMKVVMIM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCHHHHHHH
TLARFLSRYPAVDGLTVRDLVYPLLFVGGPAILIMKQPDLGTAIVIILIACSMIAYVGVR
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LATLVACLAATVPAIYLGWRYYLRDYQKNRILNFLNPERDPLGSGYHIIQSKIAVGSGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFTHGTQTQLRFLPEQHTDFAFSVFGEEWGFIGCLTLLLLYLFLIFWGLHIAGRCND
CCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
RFGSLMAVGVTAMLFWHTIINIGMVIGVFPVVGVPLPLFSYGGTSMITSMIGVGVLLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC
>Mature Secondary Structure
MIDRRLFTNFDWTLLVLVFLISAMGIVNIYSASASYTLVGAPYYLKQFYWIVAGMFLVVL
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
ACSVDYHLLEDVTYWFYGLLCVVLVAVLLMGKTSMGATRWLHLGFFSIQPSEPMKVVMIM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCHHHHHHH
TLARFLSRYPAVDGLTVRDLVYPLLFVGGPAILIMKQPDLGTAIVIILIACSMIAYVGVR
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LATLVACLAATVPAIYLGWRYYLRDYQKNRILNFLNPERDPLGSGYHIIQSKIAVGSGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFTHGTQTQLRFLPEQHTDFAFSVFGEEWGFIGCLTLLLLYLFLIFWGLHIAGRCND
CCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
RFGSLMAVGVTAMLFWHTIINIGMVIGVFPVVGVPLPLFSYGGTSMITSMIGVGVLLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]