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The map label for this gene is hlyB [H]

Identifier: 78222041

GI number: 78222041

Start: 905950

End: 907587

Strand: Reverse

Name: hlyB [H]

Synonym: Gmet_0821

Alternate gene names: 78222041

Gene position: 907587-905950 (Counterclockwise)

Preceding gene: 78222044

Following gene: 78222040

Centisome position: 22.7

GC content: 60.32

Gene sequence:

>1638_bases
ATGTTACATCGTATGAAGATCGGAACGCGGCTCGGTCTGGGGTTCGGACTTGTGGTGCTGCTGCTGGTGATTACCGGGGG
CGCGGGATTTCTGGGAGTCGAAAAGATCGACAAGGCCAGCAACGAGATTCTCTCCCAGGAGGTCAAGATCGGTGAATACT
TTTCCCGGGTGAGGGCCAATATCCTCTACATGAGGATGTATGAAAAGGACGCGTTCATCAACATAAACAATCCCGATAAG
ATCGCGGAATACGAAAAGAAATGGACCGAGAAAAAGGGGCGTCTCGATGAGTGGCTTGGCAAGTTGGGCAAACTGAAGCT
GGACGACAAGGAAAAGGGTCAGTACGCCGCGATACAGGAAAACTACAAACAATACGTTGACGGTTTCGGGCAGCTCATGG
GGCAGATCAAATCCGGCGCCATCACCAGCACCCAGCAGGCAAACGAGGCGATGAAACCGGTCAAGGAGGCGGCCCAAGCC
ATTGAAAAACTGTCCACGGAAGGAAACCGGGCGGCCTACGAGATGAGCGACAAGAAGACCAAGGAAGTCGACGCCATCGG
GCAGAGATCGGTTACGACAATAGTCATCTGCCTGTTCGCTGCTCTAGTGCTCGCCGTGGTTATAACCGTGGTCATTACCC
GCGGCATCACCAAACCGCTGCGGGCGATGAACGTCATGATGGACGACATTGCCCAGGGGGAAGGCGACCTGACCAGGCGG
ATCGAAGTCCGCTCCGACGATGAACTGGGGCACCTGGGGCGCTCCTTCAACCTCTTTGTCGAGAAGCTCCAGAAGACCAT
TGCCATGGTGGCGGATAACACGGCCCAGGTGGCTGCGGCAGCCGGCCAGGTCTATTCCTCTTCCGAGCAGATGGCCACCG
GCGCCGAGGAAGTGGCGGCCCAGGCCGGAACGGTTGCCACCGCCAGCGAGGAGATGGCGGCGACATCCAACGAAATCGCC
AACAACTGCATGCTGGCGGCGGAAGGATCGCGGGAGGCAAGCGGTTCGGCATCAGGCGGCAGCCAGGTGGTTGAGCAGAC
CGTAGCAGTGATGAACCGCATTGCCGAGCGGGTGAAAGAGGCAGCCCACACCGTTGAAGGGCTGGGAGCCCGCGGGGATC
AGATCGGCGAAATCATCGGCACCATCCAGGACATTGCCGATCAGACCAACCTGCTGGCCCTGAACGCGGCCATCGAGGCA
GCCAGGGCCGGGGAGCAGGGGCGAGGGTTTGCCGTGGTTGCCGACGAAGTGCGAGCCCTGGCCGAACGGACCACGAAGGC
GACCCGGGAGATCGGCGAGATGATCAAGGGGATCCAGCAGGAAACCGGGCGGGCAGTCTCTTCCATGGAAGAAGGGGTCA
AAGAGGTGGCCAGCGGCACCGCTGAAGCGGCCAAGTCGGGCGATGCCCTGCGGGAGATTCTCGACAGGATCACCGGCGTA
ACCGGCCAGGTGAGCCAAATCGCCACAGCAGCGGAAGAGCAGACCGCCACCACCGCCGAGATCACCAACAACATCCAGCA
GATCACGACGGTGGTGGAAGCCACGGCTCGCGGCGCCCAGGAATCCGCCACGGCGGCAAGCAGGCTGACAGACCTGGCAA
CGGAACTGCAGGGGCTCGTGGGGCAGTTCAAGGTATAA

Upstream 100 bases:

>100_bases
CCCGCAAACTTTTACCGATAAATACTACTGAAAACTGAACTTTTTCCTCGTAATTCCAAGGAACTAACTGTGCGCAAGAA
CATCAGCCAAGGAGAATGAC

Downstream 100 bases:

>100_bases
ACGACGTATTATGTCGCACCTCTCGGGTTTACTGTCATTATCACACAACCGGGAGGTGCGTCATGATCTATCTCACCACA
GACCAGTTCGACCAGGCAGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MLHRMKIGTRLGLGFGLVVLLLVITGGAGFLGVEKIDKASNEILSQEVKIGEYFSRVRANILYMRMYEKDAFININNPDK
IAEYEKKWTEKKGRLDEWLGKLGKLKLDDKEKGQYAAIQENYKQYVDGFGQLMGQIKSGAITSTQQANEAMKPVKEAAQA
IEKLSTEGNRAAYEMSDKKTKEVDAIGQRSVTTIVICLFAALVLAVVITVVITRGITKPLRAMNVMMDDIAQGEGDLTRR
IEVRSDDELGHLGRSFNLFVEKLQKTIAMVADNTAQVAAAAGQVYSSSEQMATGAEEVAAQAGTVATASEEMAATSNEIA
NNCMLAAEGSREASGSASGGSQVVEQTVAVMNRIAERVKEAAHTVEGLGARGDQIGEIIGTIQDIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKGIQQETGRAVSSMEEGVKEVASGTAEAAKSGDALREILDRITGV
TGQVSQIATAAEEQTATTAEITNNIQQITTVVEATARGAQESATAASRLTDLATELQGLVGQFKV

Sequences:

>Translated_545_residues
MLHRMKIGTRLGLGFGLVVLLLVITGGAGFLGVEKIDKASNEILSQEVKIGEYFSRVRANILYMRMYEKDAFININNPDK
IAEYEKKWTEKKGRLDEWLGKLGKLKLDDKEKGQYAAIQENYKQYVDGFGQLMGQIKSGAITSTQQANEAMKPVKEAAQA
IEKLSTEGNRAAYEMSDKKTKEVDAIGQRSVTTIVICLFAALVLAVVITVVITRGITKPLRAMNVMMDDIAQGEGDLTRR
IEVRSDDELGHLGRSFNLFVEKLQKTIAMVADNTAQVAAAAGQVYSSSEQMATGAEEVAAQAGTVATASEEMAATSNEIA
NNCMLAAEGSREASGSASGGSQVVEQTVAVMNRIAERVKEAAHTVEGLGARGDQIGEIIGTIQDIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKGIQQETGRAVSSMEEGVKEVASGTAEAAKSGDALREILDRITGV
TGQVSQIATAAEEQTATTAEITNNIQQITTVVEATARGAQESATAASRLTDLATELQGLVGQFKV
>Mature_545_residues
MLHRMKIGTRLGLGFGLVVLLLVITGGAGFLGVEKIDKASNEILSQEVKIGEYFSRVRANILYMRMYEKDAFININNPDK
IAEYEKKWTEKKGRLDEWLGKLGKLKLDDKEKGQYAAIQENYKQYVDGFGQLMGQIKSGAITSTQQANEAMKPVKEAAQA
IEKLSTEGNRAAYEMSDKKTKEVDAIGQRSVTTIVICLFAALVLAVVITVVITRGITKPLRAMNVMMDDIAQGEGDLTRR
IEVRSDDELGHLGRSFNLFVEKLQKTIAMVADNTAQVAAAAGQVYSSSEQMATGAEEVAAQAGTVATASEEMAATSNEIA
NNCMLAAEGSREASGSASGGSQVVEQTVAVMNRIAERVKEAAHTVEGLGARGDQIGEIIGTIQDIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRALAERTTKATREIGEMIKGIQQETGRAVSSMEEGVKEVASGTAEAAKSGDALREILDRITGV
TGQVSQIATAAEEQTATTAEITNNIQQITTVVEATARGAQESATAASRLTDLATELQGLVGQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=566, Percent_Identity=26.1484098939929, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI2367378, Length=523, Percent_Identity=29.0630975143403, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1788194, Length=331, Percent_Identity=31.4199395770393, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=33.4375, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789453, Length=368, Percent_Identity=29.0760869565217, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58159; Mature: 58159

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHRMKIGTRLGLGFGLVVLLLVITGGAGFLGVEKIDKASNEILSQEVKIGEYFSRVRAN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILYMRMYEKDAFININNPDKIAEYEKKWTEKKGRLDEWLGKLGKLKLDDKEKGQYAAIQE
HHHHEEECCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
NYKQYVDGFGQLMGQIKSGAITSTQQANEAMKPVKEAAQAIEKLSTEGNRAAYEMSDKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
KEVDAIGQRSVTTIVICLFAALVLAVVITVVITRGITKPLRAMNVMMDDIAQGEGDLTRR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHEE
IEVRSDDELGHLGRSFNLFVEKLQKTIAMVADNTAQVAAAAGQVYSSSEQMATGAEEVAA
EECCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCHHHHHH
QAGTVATASEEMAATSNEIANNCMLAAEGSREASGSASGGSQVVEQTVAVMNRIAERVKE
HCCCHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAHTVEGLGARGDQIGEIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHH
AERTTKATREIGEMIKGIQQETGRAVSSMEEGVKEVASGTAEAAKSGDALREILDRITGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCC
TGQVSQIATAAEEQTATTAEITNNIQQITTVVEATARGAQESATAASRLTDLATELQGLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GQFKV
HHCCC
>Mature Secondary Structure
MLHRMKIGTRLGLGFGLVVLLLVITGGAGFLGVEKIDKASNEILSQEVKIGEYFSRVRAN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILYMRMYEKDAFININNPDKIAEYEKKWTEKKGRLDEWLGKLGKLKLDDKEKGQYAAIQE
HHHHEEECCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
NYKQYVDGFGQLMGQIKSGAITSTQQANEAMKPVKEAAQAIEKLSTEGNRAAYEMSDKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
KEVDAIGQRSVTTIVICLFAALVLAVVITVVITRGITKPLRAMNVMMDDIAQGEGDLTRR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHEE
IEVRSDDELGHLGRSFNLFVEKLQKTIAMVADNTAQVAAAAGQVYSSSEQMATGAEEVAA
EECCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCHHHHHH
QAGTVATASEEMAATSNEIANNCMLAAEGSREASGSASGGSQVVEQTVAVMNRIAERVKE
HCCCHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAHTVEGLGARGDQIGEIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHH
AERTTKATREIGEMIKGIQQETGRAVSSMEEGVKEVASGTAEAAKSGDALREILDRITGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCC
TGQVSQIATAAEEQTATTAEITNNIQQITTVVEATARGAQESATAASRLTDLATELQGLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GQFKV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]