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The map label for this gene is dhaR [H]

Identifier: 78222023

GI number: 78222023

Start: 883023

End: 883613

Strand: Direct

Name: dhaR [H]

Synonym: Gmet_0803

Alternate gene names: 78222023

Gene position: 883023-883613 (Clockwise)

Preceding gene: 78222022

Following gene: 78222024

Centisome position: 22.09

GC content: 62.61

Gene sequence:

>591_bases
ATGGATAAGAACGAAACGAGAGCAACCATCATCCGCATCGGCACCGACCTCATCGGCCGTCAGGGGTTCAACGCCACCGG
CATTGATGCGGTGCTGAGGGAGGCTGGTGTACCCAAGGGCTCATTCTACTACTATTTCAGGAGCAAGGAGGAGTTCGGCC
TGGCGGTGATTGACCACTTTGCCGAGCGCTACGACCAGCGGCTCGACACCTTCCTGAACGACGATGAGGTGACACCGCTG
AATCGGCTCCGTAATCTGCTGGAGAGCGGCCTGGCGCGCCTGGAGCAGAACCAGTGCGCCAAGGGATGCCTCATCGGCAA
CCTGGGGCAGGAGCTGGCCGACCAGAACGAACGCTTCCGGGCGAGGCTCGAAGAGGTGTTTACCTCGTGGAAGAAGCGCT
ACGCCGCCTGCCTGCGGGAGGCCCAGCGTGCAGGGGAACTGGCACCGGAGCTTGACCCGTCCGTGGTGGCGGGATTCATT
CTCTCCGGCTGGGAAGGGGCTGTCCTCCGGGCCAAGGTGATGAAGTCGCCCCAGCCCCTGCGGGATTTCATCGCCACGCT
TTTTGCAACGGTGCTGCGCGAGCAGGTGTGA

Upstream 100 bases:

>100_bases
AAGCCCGCCATGTGCGGGCTTTTCCGTTTGTGATAGGAACAACCATTCACTCTAAATTCCCTCCTTGACTTTGTAGACGA
CCGGTCTAATAATGATCCCC

Downstream 100 bases:

>100_bases
AAATTTTTTTCGGCAACTAGACGACTGGTCTAATTTGAGAAGGGGAGGGGAGCATGGGAAACTCGGTATTCAAGGCGCTG
GTGGTGGAGAAGACCCCCGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MDKNETRATIIRIGTDLIGRQGFNATGIDAVLREAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDDEVTPL
NRLRNLLESGLARLEQNQCAKGCLIGNLGQELADQNERFRARLEEVFTSWKKRYAACLREAQRAGELAPELDPSVVAGFI
LSGWEGAVLRAKVMKSPQPLRDFIATLFATVLREQV

Sequences:

>Translated_196_residues
MDKNETRATIIRIGTDLIGRQGFNATGIDAVLREAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDDEVTPL
NRLRNLLESGLARLEQNQCAKGCLIGNLGQELADQNERFRARLEEVFTSWKKRYAACLREAQRAGELAPELDPSVVAGFI
LSGWEGAVLRAKVMKSPQPLRDFIATLFATVLREQV
>Mature_196_residues
MDKNETRATIIRIGTDLIGRQGFNATGIDAVLREAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDDEVTPL
NRLRNLLESGLARLEQNQCAKGCLIGNLGQELADQNERFRARLEEVFTSWKKRYAACLREAQRAGELAPELDPSVVAGFI
LSGWEGAVLRAKVMKSPQPLRDFIATLFATVLREQV

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=183, Percent_Identity=30.6010928961749, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22145; Mature: 22145

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNETRATIIRIGTDLIGRQGFNATGIDAVLREAGVPKGSFYYYFRSKEEFGLAVIDHF
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
AERYDQRLDTFLNDDEVTPLNRLRNLLESGLARLEQNQCAKGCLIGNLGQELADQNERFR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ARLEEVFTSWKKRYAACLREAQRAGELAPELDPSVVAGFILSGWEGAVLRAKVMKSPQPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHH
RDFIATLFATVLREQV
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKNETRATIIRIGTDLIGRQGFNATGIDAVLREAGVPKGSFYYYFRSKEEFGLAVIDHF
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
AERYDQRLDTFLNDDEVTPLNRLRNLLESGLARLEQNQCAKGCLIGNLGQELADQNERFR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ARLEEVFTSWKKRYAACLREAQRAGELAPELDPSVVAGFILSGWEGAVLRAKVMKSPQPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHH
RDFIATLFATVLREQV
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]