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The map label for this gene is rpoB

Identifier: 78221839

GI number: 78221839

Start: 687276

End: 691388

Strand: Direct

Name: rpoB

Synonym: Gmet_0619

Alternate gene names: 78221839

Gene position: 687276-691388 (Clockwise)

Preceding gene: 78221838

Following gene: 78221840

Centisome position: 17.19

GC content: 56.43

Gene sequence:

>4113_bases
ATGGCTTATTCAATTGCGAATAACCAGCTTCTACGCCAGAATTTCGCCAAGATCAAGAAAATCATTGACATCCCCAACCT
TATTGATATTCAAAAAAATTCCTATAAGCGTTTCCTGCAAATTGACACCCCCCCCGAAGCACGCAAGAACAGCGGGCTCG
AAGCTGTATTCAAGAGTGTTTTCCCAATTAAGGACTTTAGCGATACTGCTTCGCTTGAGTATGTTTCCTATAGCCTCGGC
ACACCGAAGTACGATGTTGAAGAATGCCACCAACGCGGGATGACCTTCGCCGCCCCCATGAAGGTGAAGGTGCGCCTCGT
CGTTTGGGACGTGAACAAGGATACTGGCGTCCGTTCTATTCGGGATATCAAGGAGCAGGAGGTCTACTTCGGCGAGATCC
CGCTCATGACCGAGAACGGCACGTTCATCATAAACGGTACCGAACGTGTTATCGTGAGCCAGCTTCACCGCTCTCCCGGT
GTTTTCTACGACCATGACAAGGGCAAGACCCATTCCAGCGGCAAGGTCCTCTATTCCGCCCGAGTGATCCCTTACCGTGG
CTCTTGGCTCGATTTCGAGTTCGACCACAAGGACATACTCTATGTCCGGATCGACCGTCGCCGCAAGATGCCGGCAACGG
TCCTCCTTAAGGCCCTTGGCAACAGTGCGGAGGAGCTTCTCAATTTTTATTACCGGAGTGAGGAGATCGGGCTCGATGGG
GAGCGGATGTGGAAGAAGGCCGACGCCGAGCTTCTGACAACTCAGAAAACCTCTTCCGACATCGTTGATTCCAAGACCGG
TGAAGTCATCATCAAGGCGAACAGAAAGTTCACCAAGGCGGCAATCCGCAAGATGACCGAGCACGGAATCACCGAGATTC
CCATTAAAGCCGAAGAGGTCTGTGGAAAGTACGCTTCTACCGATATTGTTGACCCTGCCACTGGCGAAGTGCTGGTAGAG
TGCAACGAGGAGATCTCCCAGGCTAAGCTTGACGAGATCAAGGCACGGGGCATTTCGGAGTTCAAGGTTCTTTTCATCGA
CAACCTCCATGTGACATCCTCGCTGCGGGACACACTGCTCGTCGATAAGATAAACACTACTGACGACGCGCTCATTGAGA
TCTATCGTCGCCTGCGTCCTGGTGATCCCCCGACCCTCAAGAGTGCCCAGGCACTTTTCGACAACCTCTTTTTCAATGCA
GAACGCTACGATCTCTCAGCCGTGGGACGGCTCAAGCTTAACTACAAGCTGGGACTCGGCGTCCCCCTTGACTGCCAGGT
GCTCACCAAGGAAGATATCCTTGAGGTGGTCCGGTATCTCATTGATCTGAAAAACGGCCGGGGGACCATCGATGATATCG
ACCATCTGGGCAACCGGCGGGTGCGGGCTGTGGGCGAGCTGCTGGAAAACCAGTACCGCATCGGTCTCGTCCGCATGGAG
CGGGCCATCAAGGAGCGGATGAGCCTACAGGAAGTCGAGAACCTGATGCCCCACGACCTGATCAACTCCAAGCCGGTTTC
GGCCGTGGTCAAGGAGTTTTTCGGCTCATCGCAGCTCTCGCAGTTCATGGACCAGACAAACCCGCTTTCCGAAGTTACCC
ACAAGCGGCGTCTCTCTGCCCTCGGACCAGGCGGCCTCACCCGCGAACGGGCCGGCTTCGAAGTCCGTGACGTTCACCCC
ACCCACTACGGCCGGGTCTGCCCGATCGAGACTCCTGAAGGTCCGAACATCGGTCTTATTGCATCGCTTTCCACCTACGC
CCGGATCAACGAGCACGGCTTTGTGGAAACGCCGTACCGGATCGTGAGCGAGGGGAAAGTCACCGCCGAGGTGAAGTTCT
TCTCCGCCCTTGAGGAGGAGGGGCATGCCATTGCCCAGGCCAATGCCGAGATGGATGCCGATGGCCGCTTTGTGAACGAT
TACGTCTCTGCCCGTAAGTCGGGCGAGTTCCTCCTCGTGCATCGGGACGAGCTGGAGCTTATGGACGTGGCACCGATGCA
GCTTGTTTCCGTTGCAGCATCGCTTATTCCGTTTCTTGAGAACGACGACGCCAACCGCGCCCTCATGGGCTCCAACATGC
AACGTCAGGCAGTACCGCTCCTGAAAGCCGATTCTCCGTTGGTCGGCACCGGCATGGAGCGGGTTGTCGCCAAGGATTCG
GGTGTTTCGGTTGTGGCGCGCCACACCGGCGTCGTCGAATCGGTAGATGCGTCACGCATCGTCGTCAAGATCGACGAAGA
CGAGTATGACGAGACCGGCACCGGTGTCGATATCTATAACCTCATCAAGTTTGCCCGCTCCAACCAGAACACGTGCATTA
ACCAGCGGCCGGTGGTCAAGGTTGGCGATCATGTGAAACGGGGCGATGTCATTGCTGATGGCCCGTCCACCGACATGGGG
GAACTGGCTCTGGGGCAGAACGTTGTCGTCGCCTTCATGCCCTGGGGTGGCTACAACTTCGAAGACTCGATCCTTATTTC
CGAGAAACTCACCAAGGACGACCGCTATACCTCGATCCATATCGAGGAGTTCGAGTGCGTTGCCCGTGACACCAAGCTCG
GCAAGGAAGAGATAACCTCGGATATCCCGAATCTGGGCGAGGAAACCCTCAAGGACCTGGACGAGTCCGGCATCATCCGG
ATTGGCGCTGAAGTCAAACCGGGTGACATCATGGTCGGGAAGATCACGCCGAAGGGCGAAACCCAGCTCTCGCCGGAGGA
AAAGCTTCTCCGGGCCATCTTCGGCGAAAAAGCTGGAGACGTTCGCGACACCTCCCTGCGTGTTCCGCCGGGGGTCGAGG
GGACAGTCATCGGCGCCAAAGTCTTTTCCCGTAAAGGGAATGACAAAGACTCCCGTACCGAGATGATCGAACGGATGGAG
GAGGAAAAGCTTCGCAAGGACGAGCAGGACGAGATCCGGATTATCCGTGATTCTGCTGTCGGCAAGCTGAAAAGGCTTCT
GGTCGGCAAGACCGCTGCCGTGAAGGTGGAGGACAAAAACGGCAAGACGGTTATCGCCAAGGATGCCGCCATCACGGAAG
AGGCCCTCACGGCAATCCCCCTCGATCGTTGGGATGAGATTTCGGTCAGTGGCGGGGAGGGGGTCGAGGAGAAGGTTGCT
GCGATCCTTGCCACGCTCCAACAGCAGATTGATATCATAAAATATGTCTTTGACGATAAGGTCCAGAAGCTGAAACGAGG
CGATGACCTTCCCCCGGGCGTTATCAAGATGGTCAAGGTTTACATTGCCATCAAGCGCAAGCTTCAGGTCGGCGACAAGA
TGGCAGGCCGCCACGGTAACAAGGGTGTTGTGTCCCGTATCCTCCCCGAGGAAGACATGCCGTACATGGAGGATGGCCGT
CCCGTCGAGATCGTGCTGAACCCCCTGGGTGTTCCTTCCCGTATGAACGTGGGGCAGATCCTCGAAACCCATCTGGGATG
GGCTGCCAAGGGAATCGGCTGGAAGATCGAGGAAATGCTTGAGAAGCATTCTCCGTCTGCCACGATCAAGGAGTATCTCC
AGAAGGTTTACGGCTCCAAGGAAATGAATGCGTTCCTTGACTCTCTCAACGAGGAGGAACTGATAAACGTCGCCAAGCGT
CTCCAACGCGGAGTTCCGATGGCGTCGCCCGTCTTTGAGGGGGCTTCGGAGGAGCAGATTCGAAGCATGCTCGACAAGGC
CGGTTTCGACGAGACCGCCCAGGTCAGACTTTTCGACGGCAAGACCGGAGAACCCTTCAAGCACAAGGTCACGGTCGGGG
TCATGTACGTCCTCAAGCTCCATCACCTGGTTGACGACAAGATCCACGCCCGGTCCATCGGCCCCTACAGCCTCGTGACC
CAACAGCCTCTGGGCGGCAAGGCTCAGTTTGGTGGCCAGCGTCTCGGTGAAATGGAGGTCTGGGCCATGGAAGCATACGG
CGCCGCCTATGCTCTCCAGGAATTCCTGACGGTGAAATCCGATGACGTTGCAGGCCGTACGCGCATGTACGAGGCCATTG
TCAAAGGAAAGCATACCCTCGAGCCGGGACTCCCGGAGTCGTTCAACGTCCTGATAAAGGAACTCCAGTCGCTGTGTCTC
GATGTGGAACTCCTGGAAGGCGACGAGGATTAG

Upstream 100 bases:

>100_bases
TTTTAGTTCCGAATTCGTATCCGCTGGCTCCGGGCAATATCGGAGAAGGCACTAAATCCAGGGGGTTAGAGGCTCCATGA
GCCTCGCCAAAGGAGAAAAC

Downstream 100 bases:

>100_bases
AGTTGGTCATCCAAGACATTGACCGCCTGAACGATCACATGAGCAGCAGCCACTCCTAAACAGAGGAGGATTAGACATTG
GAAGATTTTTTCAGCTTTTT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1370; Mature: 1369

Protein sequence:

>1370_residues
MAYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVSYSLG
TPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDG
ERMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEVCGKYASTDIVDPATGEVLVE
CNEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLLVDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNA
ERYDLSAVGRLKLNYKLGLGVPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVND
YVSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
GVSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMG
ELALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIR
IGAEVKPGDIMVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERME
EEKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIPLDRWDEISVSGGEGVEEKVA
AILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGR
PVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKR
LQRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVT
QQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCL
DVELLEGDED

Sequences:

>Translated_1370_residues
MAYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVSYSLG
TPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDG
ERMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEVCGKYASTDIVDPATGEVLVE
CNEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLLVDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNA
ERYDLSAVGRLKLNYKLGLGVPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVND
YVSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
GVSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMG
ELALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIR
IGAEVKPGDIMVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERME
EEKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIPLDRWDEISVSGGEGVEEKVA
AILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGR
PVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKR
LQRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVT
QQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCL
DVELLEGDED
>Mature_1369_residues
AYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSVFPIKDFSDTASLEYVSYSLGT
PKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSIRDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGV
FYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDGE
RMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEVCGKYASTDIVDPATGEVLVEC
NEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLLVDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNAE
RYDLSAVGRLKLNYKLGLGVPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRMER
AIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPT
HYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYRIVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVNDY
VSARKSGEFLLVHRDELELMDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDSG
VSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVKVGDHVKRGDVIADGPSTDMGE
LALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIHIEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIRI
GAEVKPGDIMVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERMEE
EKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIPLDRWDEISVSGGEGVEEKVAA
ILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRP
VEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKRL
QRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQ
QPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLD
VELLEGDED

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=292, Percent_Identity=30.1369863013699, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI238908503, Length=292, Percent_Identity=30.1369863013699, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI33469941, Length=254, Percent_Identity=30.7086614173228, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI212286172, Length=254, Percent_Identity=30.7086614173228, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI4505941, Length=301, Percent_Identity=28.2392026578073, Blast_Score=115, Evalue=4e-25,
Organism=Escherichia coli, GI1790419, Length=1371, Percent_Identity=57.1845368344274, Blast_Score=1617, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=292, Percent_Identity=28.4246575342466, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=246, Percent_Identity=29.6747967479675, Blast_Score=113, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=30.0813008130081, Blast_Score=110, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=292, Percent_Identity=29.1095890410959, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=268, Percent_Identity=30.5970149253731, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=247, Percent_Identity=29.9595141700405, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647877, Length=293, Percent_Identity=30.0341296928328, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136444, Length=246, Percent_Identity=29.6747967479675, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136446, Length=253, Percent_Identity=30.4347826086957, Blast_Score=110, Evalue=5e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_GEOMG (Q39Y13)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383586.1
- ProteinModelPortal:   Q39Y13
- STRING:   Q39Y13
- GeneID:   3739242
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0619
- NMPDR:   fig|269799.3.peg.646
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   Q39Y13
- ProtClustDB:   PRK00405
- BioCyc:   GMET269799:GMET_0619-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 152881; Mature: 152750

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSV
CCEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHCCCHHHHHHHH
FPIKDFSDTASLEYVSYSLGTPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSI
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
RDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDG
EEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCH
ERMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEV
HHHHHHHCHHHEEECCCCCHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCHHHH
CGKYASTDIVDPATGEVLVECNEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLL
HCHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHE
VDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNAERYDLSAVGRLKLNYKLGLG
EECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCC
VPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
CCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYR
CCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHH
IVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVNDYVSARKSGEFLLVHRDELEL
HHCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCH
MDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCEECCCCCCCCCHHHHHCCCC
GVSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVK
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
VGDHVKRGDVIADGPSTDMGELALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIH
CCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEEE
IEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIRIGAEVKPGDIMVGKITPKGE
EHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCC
TQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERME
CCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHH
EEKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIP
HHHHCCCCCCHHEEEHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHCC
LDRWDEISVSGGEGVEEKVAAILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKV
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQI
HHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKR
HHHHHCHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
LQRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKL
HHHCCCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
HHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKS
HHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC
DDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGDED
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCC
>Mature Secondary Structure 
AYSIANNQLLRQNFAKIKKIIDIPNLIDIQKNSYKRFLQIDTPPEARKNSGLEAVFKSV
CEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHCCCHHHHHHHH
FPIKDFSDTASLEYVSYSLGTPKYDVEECHQRGMTFAAPMKVKVRLVVWDVNKDTGVRSI
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
RDIKEQEVYFGEIPLMTENGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGNSAEELLNFYYRSEEIGLDG
EEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCH
ERMWKKADAELLTTQKTSSDIVDSKTGEVIIKANRKFTKAAIRKMTEHGITEIPIKAEEV
HHHHHHHCHHHEEECCCCCHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCHHHH
CGKYASTDIVDPATGEVLVECNEEISQAKLDEIKARGISEFKVLFIDNLHVTSSLRDTLL
HCHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHE
VDKINTTDDALIEIYRRLRPGDPPTLKSAQALFDNLFFNAERYDLSAVGRLKLNYKLGLG
EECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCC
VPLDCQVLTKEDILEVVRYLIDLKNGRGTIDDIDHLGNRRVRAVGELLENQYRIGLVRME
CCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
RAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINEHGFVETPYR
CCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHH
IVSEGKVTAEVKFFSALEEEGHAIAQANAEMDADGRFVNDYVSARKSGEFLLVHRDELEL
HHCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCH
MDVAPMQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLKADSPLVGTGMERVVAKDS
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCEECCCCCCCCCHHHHHCCCC
GVSVVARHTGVVESVDASRIVVKIDEDEYDETGTGVDIYNLIKFARSNQNTCINQRPVVK
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
VGDHVKRGDVIADGPSTDMGELALGQNVVVAFMPWGGYNFEDSILISEKLTKDDRYTSIH
CCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEEE
IEEFECVARDTKLGKEEITSDIPNLGEETLKDLDESGIIRIGAEVKPGDIMVGKITPKGE
EHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCC
TQLSPEEKLLRAIFGEKAGDVRDTSLRVPPGVEGTVIGAKVFSRKGNDKDSRTEMIERME
CCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHH
EEKLRKDEQDEIRIIRDSAVGKLKRLLVGKTAAVKVEDKNGKTVIAKDAAITEEALTAIP
HHHHCCCCCCHHEEEHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHCC
LDRWDEISVSGGEGVEEKVAAILATLQQQIDIIKYVFDDKVQKLKRGDDLPPGVIKMVKV
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQI
HHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHH
LETHLGWAAKGIGWKIEEMLEKHSPSATIKEYLQKVYGSKEMNAFLDSLNEEELINVAKR
HHHHHCHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
LQRGVPMASPVFEGASEEQIRSMLDKAGFDETAQVRLFDGKTGEPFKHKVTVGVMYVLKL
HHHCCCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
HHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKS
HHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC
DDVAGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGDED
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA