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The map label for this gene is pqqE [H]

Identifier: 78221787

GI number: 78221787

Start: 608906

End: 609904

Strand: Direct

Name: pqqE [H]

Synonym: Gmet_0566

Alternate gene names: 78221787

Gene position: 608906-609904 (Clockwise)

Preceding gene: 78221786

Following gene: 78221788

Centisome position: 15.23

GC content: 66.17

Gene sequence:

>999_bases
ATGCCGAATGAGGTTGTCCTCGAAGCGCCGTTGACTATCAACTGGGCCATCAACAACAGCTGCAACTTCGCCTGCCGCCA
CTGCTACAGCCGTGGGGACACCCACGAGGAGCTCCCCCGGGAGGTCCTTCTCGCCTGTCTGGAAAAGGTGGCGCAGGCCG
GGGTCTTCTCCGTCAATTTCGGCGGCGGGGAGCCGCTTCTCCATCCCGGTATCCTGGAGATCGCCTGCCACGCCAGGAGC
CTGGGGCTGCGGATCTCCATGAACAGCAACGGCTGGCTCCTGGACCGGGAGATGGCCGGGGCGCTGCGGGACGCTGGCTT
CACCAAGGTGGGGATCAGCATCGATAGCCACATCCCCAAGGTCCACGACCGGTTCCGAGGCGTTGCGGGGAGCCACGGCC
GGGCCGTGGCGGCCCTGGGGGACCTGGCGGAGGCCGGCATCGACACCTCCATCTCCACGGTCATCTGCCGGATCAACAAT
ACCGCCATCGACGACCTGGTGGCCTTTGCCCGGGAGCAGGGGGCGCGGCAGCTCAACTTCCACAACTTCAAATGCTCGGG
GCTCGGCCTTTCCCACAAGGATGAACTGGACCTGACGCCGGAGGAGTGGCAGGAGTTCTACCGGCGCGCCCTGGCCGCCA
GGGACGGGGAGAAGGGGCTCGACATCTCCCTGGATGATCCGATCATCGCCCTTCTGGGGGCCCGTGACACCGGAAGCCTC
GTCAAGGGGAGCGTCTGCGGCAAGCTCTCCCTCAACATCAAGGCCAACGGCGACATGACCCCCTGCGGCTTCATCCCCAT
CGTCATCGGCAACATCGTCCGGGACGACCTGAAGCAGGTCTGGCGCGATTCGGCGGTGCTGGAGAAGATGCGCAACAAGA
AGCCCACGGGCAAATGCGCCGGCTGCGGCAAGTACGAAGACTGCCTCGGCGGCTGCTCCGCCCGGGCCCTGGCCCTCACC
GGCGACCTGAACAGCCCCGACCCCCACTGCTGGGCGTAA

Upstream 100 bases:

>100_bases
GTAGCGGAGCTCCTGCCACAGTTCGAGGTGGACGAGGCGGTGCTCCGGGAGGACGTCCGGGCTTTCCTGGACGAGCTGGC
CGCCAAGGGGTTCGTCAGCC

Downstream 100 bases:

>100_bases
TCCCCGCTCCGCTCCCTGCCGGATCAAGGATGATTCATGGAACTGGCATCCCCCATAACCATCTACTGGGACCTCCCCCC
CGACGCCCATGAGCCGTCCC

Product: radical SAM family protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPNEVVLEAPLTINWAINNSCNFACRHCYSRGDTHEELPREVLLACLEKVAQAGVFSVNFGGGEPLLHPGILEIACHARS
LGLRISMNSNGWLLDREMAGALRDAGFTKVGISIDSHIPKVHDRFRGVAGSHGRAVAALGDLAEAGIDTSISTVICRINN
TAIDDLVAFAREQGARQLNFHNFKCSGLGLSHKDELDLTPEEWQEFYRRALAARDGEKGLDISLDDPIIALLGARDTGSL
VKGSVCGKLSLNIKANGDMTPCGFIPIVIGNIVRDDLKQVWRDSAVLEKMRNKKPTGKCAGCGKYEDCLGGCSARALALT
GDLNSPDPHCWA

Sequences:

>Translated_332_residues
MPNEVVLEAPLTINWAINNSCNFACRHCYSRGDTHEELPREVLLACLEKVAQAGVFSVNFGGGEPLLHPGILEIACHARS
LGLRISMNSNGWLLDREMAGALRDAGFTKVGISIDSHIPKVHDRFRGVAGSHGRAVAALGDLAEAGIDTSISTVICRINN
TAIDDLVAFAREQGARQLNFHNFKCSGLGLSHKDELDLTPEEWQEFYRRALAARDGEKGLDISLDDPIIALLGARDTGSL
VKGSVCGKLSLNIKANGDMTPCGFIPIVIGNIVRDDLKQVWRDSAVLEKMRNKKPTGKCAGCGKYEDCLGGCSARALALT
GDLNSPDPHCWA
>Mature_331_residues
PNEVVLEAPLTINWAINNSCNFACRHCYSRGDTHEELPREVLLACLEKVAQAGVFSVNFGGGEPLLHPGILEIACHARSL
GLRISMNSNGWLLDREMAGALRDAGFTKVGISIDSHIPKVHDRFRGVAGSHGRAVAALGDLAEAGIDTSISTVICRINNT
AIDDLVAFAREQGARQLNFHNFKCSGLGLSHKDELDLTPEEWQEFYRRALAARDGEKGLDISLDDPIIALLGARDTGSLV
KGSVCGKLSLNIKANGDMTPCGFIPIVIGNIVRDDLKQVWRDSAVLEKMRNKKPTGKCAGCGKYEDCLGGCSARALALTG
DLNSPDPHCWA

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 35772; Mature: 35641

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNEVVLEAPLTINWAINNSCNFACRHCYSRGDTHEELPREVLLACLEKVAQAGVFSVNF
CCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
GGGEPLLHPGILEIACHARSLGLRISMNSNGWLLDREMAGALRDAGFTKVGISIDSHIPK
CCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCEEEHHHHHHHHHCCCEEEEEEHHCCCCH
VHDRFRGVAGSHGRAVAALGDLAEAGIDTSISTVICRINNTAIDDLVAFAREQGARQLNF
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCC
HNFKCSGLGLSHKDELDLTPEEWQEFYRRALAARDGEKGLDISLDDPIIALLGARDTGSL
CCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCH
VKGSVCGKLSLNIKANGDMTPCGFIPIVIGNIVRDDLKQVWRDSAVLEKMRNKKPTGKCA
HCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GCGKYEDCLGGCSARALALTGDLNSPDPHCWA
CCCCHHHHHCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PNEVVLEAPLTINWAINNSCNFACRHCYSRGDTHEELPREVLLACLEKVAQAGVFSVNF
CCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
GGGEPLLHPGILEIACHARSLGLRISMNSNGWLLDREMAGALRDAGFTKVGISIDSHIPK
CCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCEEEHHHHHHHHHCCCEEEEEEHHCCCCH
VHDRFRGVAGSHGRAVAALGDLAEAGIDTSISTVICRINNTAIDDLVAFAREQGARQLNF
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCC
HNFKCSGLGLSHKDELDLTPEEWQEFYRRALAARDGEKGLDISLDDPIIALLGARDTGSL
CCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCH
VKGSVCGKLSLNIKANGDMTPCGFIPIVIGNIVRDDLKQVWRDSAVLEKMRNKKPTGKCA
HCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GCGKYEDCLGGCSARALALTGDLNSPDPHCWA
CCCCHHHHHCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11111029 [H]