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The map label for this gene is qor [H]

Identifier: 78221454

GI number: 78221454

Start: 263106

End: 264068

Strand: Direct

Name: qor [H]

Synonym: Gmet_0231

Alternate gene names: 78221454

Gene position: 263106-264068 (Clockwise)

Preceding gene: 78221452

Following gene: 78221456

Centisome position: 6.58

GC content: 66.98

Gene sequence:

>963_bases
ATGAAAGCTATTCGAGTGCGTGAATTTGGCGAACCGGAAGTGATGGGGCTAGAAGACGTGGCCCCCCTGACCCCGGGACC
GGCAGAGGTCGTGGTCAGGCTGCACGCCGTGGGGGTGAACCCGGTTGATGCCTATATCCGCTCCGGCCAGTACCGCCCTG
ACCTGAAACTTCCCTACACGCCCGGCCTCGACGGGGCCGGCGTCATCAGTGCCGTCGGTTCGGAAGTCAAGCACCGGCAC
GTGGGACAGCGGGTCTATGTCGCCTGGTCCCTGAGCGGTACCTATGCGGAGGAGGTCCTCTGCAAGGAATTCCAGACCCA
TCCGCTTCCCGACGGGGTCAGCTTCGCCCAGGGCGCGGCCATCGGCGTCCCCTATGGCGCCGCATTCCGGGCGCTGTTCC
AGCGTGCCCATGCGGTGGCAGGGGAAACGGTGCTGATCCATGGCGCGAGCGGCGGCGTGGGGATTGCGGCGGTGCAGCTC
GCCCGGAGGGCCGGCATGTGGGTGATCGGTACCGCCGGCACGGAGAAGGGCGAGGCGCTGGTGAGGGCCCAGGGTGCCCA
CCATGTCCTGAACCACCGTGTCGAGGGGTATCTGGACAGGCTGCAGGAGTTCCCCTGCGGCAAGGGGGTGGACGTTATCG
TGGAGATGCTCGCCAACGTGAACCTGGACCGTGACCTTGGGGTGCTGGCAAAGGGGGGCCGGGTGGTGGTGGTTGGCAGC
CGCGGCCGGGTGGAGATCGATCCCCGCACCGCCATGGGAAAGGAAGCCGCGATCCTTGGCATGACCCTCTACAACGCCAG
CGACAAGGAACTGGCCGGCATGCATGCGGCATTTGTCGAGGGGCTGGCCAACGGCACCCTCAGGCCGGTGGTGAGCCGGG
AGCTCCCCCTTGCCGCCGCGGCTGAGGCCCATCACGCGGTCATGGAGTCGAGCACCTTCGGCAAGATCGTGCTGCTTCCG
TGA

Upstream 100 bases:

>100_bases
GAAATGCGGCTTGCTTACCAGCATCTCTGCCGGTCACTGCTGGCGGTGATATAATGGGAATCAAAAGGAGCCAAAAGAGA
TAAAGGAATCGGTGATCATC

Downstream 100 bases:

>100_bases
GTGGGGCAGACGGCACTCACGAGGCGATGGCATACACCTCCGAGGAGATCGTGAGGTTCCCTTCGTCGAGCGCAAGGGGA
TGGGCACTATGCCCGATCAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKAIRVREFGEPEVMGLEDVAPLTPGPAEVVVRLHAVGVNPVDAYIRSGQYRPDLKLPYTPGLDGAGVISAVGSEVKHRH
VGQRVYVAWSLSGTYAEEVLCKEFQTHPLPDGVSFAQGAAIGVPYGAAFRALFQRAHAVAGETVLIHGASGGVGIAAVQL
ARRAGMWVIGTAGTEKGEALVRAQGAHHVLNHRVEGYLDRLQEFPCGKGVDVIVEMLANVNLDRDLGVLAKGGRVVVVGS
RGRVEIDPRTAMGKEAAILGMTLYNASDKELAGMHAAFVEGLANGTLRPVVSRELPLAAAAEAHHAVMESSTFGKIVLLP

Sequences:

>Translated_320_residues
MKAIRVREFGEPEVMGLEDVAPLTPGPAEVVVRLHAVGVNPVDAYIRSGQYRPDLKLPYTPGLDGAGVISAVGSEVKHRH
VGQRVYVAWSLSGTYAEEVLCKEFQTHPLPDGVSFAQGAAIGVPYGAAFRALFQRAHAVAGETVLIHGASGGVGIAAVQL
ARRAGMWVIGTAGTEKGEALVRAQGAHHVLNHRVEGYLDRLQEFPCGKGVDVIVEMLANVNLDRDLGVLAKGGRVVVVGS
RGRVEIDPRTAMGKEAAILGMTLYNASDKELAGMHAAFVEGLANGTLRPVVSRELPLAAAAEAHHAVMESSTFGKIVLLP
>Mature_320_residues
MKAIRVREFGEPEVMGLEDVAPLTPGPAEVVVRLHAVGVNPVDAYIRSGQYRPDLKLPYTPGLDGAGVISAVGSEVKHRH
VGQRVYVAWSLSGTYAEEVLCKEFQTHPLPDGVSFAQGAAIGVPYGAAFRALFQRAHAVAGETVLIHGASGGVGIAAVQL
ARRAGMWVIGTAGTEKGEALVRAQGAHHVLNHRVEGYLDRLQEFPCGKGVDVIVEMLANVNLDRDLGVLAKGGRVVVVGS
RGRVEIDPRTAMGKEAAILGMTLYNASDKELAGMHAAFVEGLANGTLRPVVSRELPLAAAAEAHHAVMESSTFGKIVLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=321, Percent_Identity=49.2211838006231, Blast_Score=315, Evalue=4e-86,
Organism=Homo sapiens, GI13236495, Length=321, Percent_Identity=49.2211838006231, Blast_Score=315, Evalue=4e-86,
Organism=Homo sapiens, GI194239676, Length=321, Percent_Identity=43.3021806853583, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=49.2063492063492, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=31.5286624203822, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=29.483282674772, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=29.483282674772, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=29.0598290598291, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI47519420, Length=362, Percent_Identity=26.7955801104972, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41872631, Length=316, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790485, Length=326, Percent_Identity=31.5950920245399, Blast_Score=131, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17507255, Length=313, Percent_Identity=40.8945686900958, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17562876, Length=330, Percent_Identity=26.969696969697, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=26.8292682926829, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=310, Percent_Identity=25.4838709677419, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=205, Percent_Identity=26.3414634146341, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550423, Length=171, Percent_Identity=32.1637426900585, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581345, Length=270, Percent_Identity=25.1851851851852, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33736; Mature: 33736

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIRVREFGEPEVMGLEDVAPLTPGPAEVVVRLHAVGVNPVDAYIRSGQYRPDLKLPYT
CCCEECCCCCCCCCCCHHHCCCCCCCHHHHEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
PGLDGAGVISAVGSEVKHRHVGQRVYVAWSLSGTYAEEVLCKEFQTHPLPDGVSFAQGAA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHCCCE
IGVPYGAAFRALFQRAHAVAGETVLIHGASGGVGIAAVQLARRAGMWVIGTAGTEKGEAL
ECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEE
VRAQGAHHVLNHRVEGYLDRLQEFPCGKGVDVIVEMLANVNLDRDLGVLAKGGRVVVVGS
EEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEECCCEEEEECC
RGRVEIDPRTAMGKEAAILGMTLYNASDKELAGMHAAFVEGLANGTLRPVVSRELPLAAA
CCEEEECCCHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHH
AEAHHAVMESSTFGKIVLLP
HHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKAIRVREFGEPEVMGLEDVAPLTPGPAEVVVRLHAVGVNPVDAYIRSGQYRPDLKLPYT
CCCEECCCCCCCCCCCHHHCCCCCCCHHHHEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
PGLDGAGVISAVGSEVKHRHVGQRVYVAWSLSGTYAEEVLCKEFQTHPLPDGVSFAQGAA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHCCCE
IGVPYGAAFRALFQRAHAVAGETVLIHGASGGVGIAAVQLARRAGMWVIGTAGTEKGEAL
ECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEE
VRAQGAHHVLNHRVEGYLDRLQEFPCGKGVDVIVEMLANVNLDRDLGVLAKGGRVVVVGS
EEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEECCCEEEEECC
RGRVEIDPRTAMGKEAAILGMTLYNASDKELAGMHAAFVEGLANGTLRPVVSRELPLAAA
CCEEEECCCHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHH
AEAHHAVMESSTFGKIVLLP
HHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]