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The map label for this gene is cbbY [H]

Identifier: 78221449

GI number: 78221449

Start: 257812

End: 258468

Strand: Direct

Name: cbbY [H]

Synonym: Gmet_0226

Alternate gene names: 78221449

Gene position: 257812-258468 (Clockwise)

Preceding gene: 78221447

Following gene: 78221450

Centisome position: 6.45

GC content: 68.19

Gene sequence:

>657_bases
ATGTTTGAGGGGATTTTCTGGGACAACGACGGGGTGTTGATGGAGACCGAGCACCTCTACTATCAGGCCAATGCCGAGGC
GTTGGCCCAGGCGGGGGTGACGCTTACCCTTGACGACTTTCGCCGGATCTCCCTGCGCCAGGGGGAGAGCGTGCTTGGCT
TGGCCGCCGGCGCGGGGCTGGGTGACGAGGAGGCTACGGCGCTGCGCCGGGTGCGGGACGGGATCTATTACCGGCTTCTG
GGGGAGGAGGCCCGGGTGATGTCCGGGGTGCGGGAAACCCTGGCGCGGCTCCACGGCCGGCTCCCCATGGCGATCGTCAC
CAGCTGCCGCCGGGAGAACTTCCTGCAGATGCACCGGCAGAGCGGACTCCTCGACTACTTCGATTTCATCCTCACCCGCG
AGGACTACGGCGCGTCCAAGCCCGATCCCGAGCCATACCGGACCGCCTGCTCCCGGGTCGGGCTCGACCCCGGTCGCTGT
CTGGCAATTGAGGATTCGGAGCGGGGTGTAACCTCCGCCGCCCGGGCCGGGCTCGTCGTTGCCGCGATCCCCGGCGACAT
GAACCGGGGGGGCGATTTCGGGGCCGCCCGCTGGCTTCTGGACGGCGTCCGCGAACTGCCGGCGCTTCTGAAGCTCGACG
AGGCGCAAGGATCGTAA

Upstream 100 bases:

>100_bases
CCCCTCTTGCAGTTTTGCACGACTTTACACCACAATGGTTGGGACGGCTGAACGTGGAACGTACGTTTACCCATGGACGG
AAGGCGAGGCGGGCACGAAG

Downstream 100 bases:

>100_bases
TACCACCGCGGCGCCGCCTCCACCAAGCGTTGACAAAAACACCGCCGCCATGTCATAAATCAACTGCCTGACGGGAAGCC
GCTTCCACCTCATGAAGCGG

Product: HAD family hydrolase

Products: Beta-D-Glucose 6- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MFEGIFWDNDGVLMETEHLYYQANAEALAQAGVTLTLDDFRRISLRQGESVLGLAAGAGLGDEEATALRRVRDGIYYRLL
GEEARVMSGVRETLARLHGRLPMAIVTSCRRENFLQMHRQSGLLDYFDFILTREDYGASKPDPEPYRTACSRVGLDPGRC
LAIEDSERGVTSAARAGLVVAAIPGDMNRGGDFGAARWLLDGVRELPALLKLDEAQGS

Sequences:

>Translated_218_residues
MFEGIFWDNDGVLMETEHLYYQANAEALAQAGVTLTLDDFRRISLRQGESVLGLAAGAGLGDEEATALRRVRDGIYYRLL
GEEARVMSGVRETLARLHGRLPMAIVTSCRRENFLQMHRQSGLLDYFDFILTREDYGASKPDPEPYRTACSRVGLDPGRC
LAIEDSERGVTSAARAGLVVAAIPGDMNRGGDFGAARWLLDGVRELPALLKLDEAQGS
>Mature_218_residues
MFEGIFWDNDGVLMETEHLYYQANAEALAQAGVTLTLDDFRRISLRQGESVLGLAAGAGLGDEEATALRRVRDGIYYRLL
GEEARVMSGVRETLARLHGRLPMAIVTSCRRENFLQMHRQSGLLDYFDFILTREDYGASKPDPEPYRTACSRVGLDPGRC
LAIEDSERGVTSAARAGLVVAAIPGDMNRGGDFGAARWLLDGVRELPALLKLDEAQGS

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=184, Percent_Identity=25, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789046, Length=181, Percent_Identity=23.7569060773481, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6 [C]

Molecular weight: Translated: 23938; Mature: 23938

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGIFWDNDGVLMETEHLYYQANAEALAQAGVTLTLDDFRRISLRQGESVLGLAAGAGL
CCCCEEECCCCEEEEECCEEEECCHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEECCCCC
GDEEATALRRVRDGIYYRLLGEEARVMSGVRETLARLHGRLPMAIVTSCRRENFLQMHRQ
CCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SGLLDYFDFILTREDYGASKPDPEPYRTACSRVGLDPGRCLAIEDSERGVTSAARAGLVV
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCEEE
AAIPGDMNRGGDFGAARWLLDGVRELPALLKLDEAQGS
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFEGIFWDNDGVLMETEHLYYQANAEALAQAGVTLTLDDFRRISLRQGESVLGLAAGAGL
CCCCEEECCCCEEEEECCEEEECCHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEECCCCC
GDEEATALRRVRDGIYYRLLGEEARVMSGVRETLARLHGRLPMAIVTSCRRENFLQMHRQ
CCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SGLLDYFDFILTREDYGASKPDPEPYRTACSRVGLDPGRCLAIEDSERGVTSAARAGLVV
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCEEE
AAIPGDMNRGGDFGAARWLLDGVRELPALLKLDEAQGS
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Beta-D-Glucose 1-Phosphate [C]

Specific reaction: Beta-D-Glucose 1-Phosphate = Beta-D-Glucose 6- Phosphate. [C]

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA