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The map label for this gene is dapL [H]

Identifier: 78221437

GI number: 78221437

Start: 246743

End: 247975

Strand: Direct

Name: dapL [H]

Synonym: Gmet_0213

Alternate gene names: 78221437

Gene position: 246743-247975 (Clockwise)

Preceding gene: 78221436

Following gene: 78221438

Centisome position: 6.17

GC content: 61.56

Gene sequence:

>1233_bases
ATGGCAAAAATCAACGACAACTACCTGAAACTGAAGGCCGGCTACCTCTTTCCCGAGATCGGCCGCCGCGTGCGGGAGTT
TTCCGCCGCCAACCCCGAGGCCAAGGTCATCCGGCTCGGCATCGGCGACGTGACCCGCCCCCTGGCCCCGGCCATCATCA
AGGCGTTCCACGACGCCGTGGACGATCTGGCCACCATCGACAACTTCGCCGGCTATGGCCCGGAGCAGGGGTACGACTGG
CTCATCAACGCCATCATCGAGAAGTCCTACAAGCCCCTGGGCGTTTCCCTCAAGACCGAGGAGATGTTCATCTCCGACGG
CTCCAAGTGCGACTGCGCCAACATCCTCGACATCTTCGCCCTCGACAACGTCGTTGCCATCGGCGATCCGGTCTACCCGG
TCTACAACGACACCAACGTCATGATCGGCCGCACCGGCGATGCCGACGAGAAGGGGTACTACAAGGGGATCGTCTACATG
CCCTGCACCGAGGCGAACGGCTTCATCCCGTCGCTCCCCACGGAAAAAGTGGACATCATCTACCTCTGCTTCCCCAATAA
TCCCACCGGCACCGTGGCCACCAAGGCCGAGCTGAAAAAGTGGGTCGACTACGCCAACGCCAACGATGCCGTCATCTTCT
TCGACGCCGCCTATGAGGCCTTCATCACCGATCCCGCAATCCCACACTCCATCTACGAGATCGAAGGGGCCAAGAAGTGC
GCCATCGAATTCCGCTCCTTCTCCAAGACCGCCGGTTTCACCGGTGTCCGCTGCGGCCTCGTGGTCGTTCCGGAAGAGGT
GATGGGCACCACGCCGACGGGGGAGAAGTACAGCTTCAACAAGCTCTGGCTCCGCCGCACCACCACCAAGTTCAACGGCG
CCTCCTACCCGGTCCAGAAGGCCGCCGCCGCCGTCTACTCCGACGAGGGATGGAAGCAGAACAAAGAGATCATCGACTAC
TACATGGAGAACGCCCGGATCATCCGCGAAGGCCTCGCCGCCGCCGGCCTTACAGTCTACGGCGGGGTCAACGCCCCCTA
CATCTGGCTGAAAACGCCGGGCGGCATGAGCAGCTGGGACTTCTTCGACAAACTTCTCACTGAGTGCAACGTCGTGGGGA
CGCCGGGAAGCGGCTTCGGCCCCAGCGGCGAAGGGTTCTTCCGGCTCTCGGCCTTCGGCCATCGCGAGAATGTGATTGAG
GCGGTGGAGAGGATAAAGAAGAATCTGAAGTAG

Upstream 100 bases:

>100_bases
AAAATCGACATCCCGTAGGTTAAACCGAAAACCTTGAACCCGATTTGCCGCTCCATGCGGCATTTCCTTTATAAAAACGA
ATCTGGAGGAATTACCGAAG

Downstream 100 bases:

>100_bases
GATGAATCGAAAGGGCGCCCGTTGCGGCGCCCTTTTTATATTGTGGTCAGGAGCTGGGAAATTTTTCCCGTTGACGCAAT
GCTTGACTATGTTATTGTAG

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAKINDNYLKLKAGYLFPEIGRRVREFSAANPEAKVIRLGIGDVTRPLAPAIIKAFHDAVDDLATIDNFAGYGPEQGYDW
LINAIIEKSYKPLGVSLKTEEMFISDGSKCDCANILDIFALDNVVAIGDPVYPVYNDTNVMIGRTGDADEKGYYKGIVYM
PCTEANGFIPSLPTEKVDIIYLCFPNNPTGTVATKAELKKWVDYANANDAVIFFDAAYEAFITDPAIPHSIYEIEGAKKC
AIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTPTGEKYSFNKLWLRRTTTKFNGASYPVQKAAAAVYSDEGWKQNKEIIDY
YMENARIIREGLAAAGLTVYGGVNAPYIWLKTPGGMSSWDFFDKLLTECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIE
AVERIKKNLK

Sequences:

>Translated_410_residues
MAKINDNYLKLKAGYLFPEIGRRVREFSAANPEAKVIRLGIGDVTRPLAPAIIKAFHDAVDDLATIDNFAGYGPEQGYDW
LINAIIEKSYKPLGVSLKTEEMFISDGSKCDCANILDIFALDNVVAIGDPVYPVYNDTNVMIGRTGDADEKGYYKGIVYM
PCTEANGFIPSLPTEKVDIIYLCFPNNPTGTVATKAELKKWVDYANANDAVIFFDAAYEAFITDPAIPHSIYEIEGAKKC
AIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTPTGEKYSFNKLWLRRTTTKFNGASYPVQKAAAAVYSDEGWKQNKEIIDY
YMENARIIREGLAAAGLTVYGGVNAPYIWLKTPGGMSSWDFFDKLLTECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIE
AVERIKKNLK
>Mature_409_residues
AKINDNYLKLKAGYLFPEIGRRVREFSAANPEAKVIRLGIGDVTRPLAPAIIKAFHDAVDDLATIDNFAGYGPEQGYDWL
INAIIEKSYKPLGVSLKTEEMFISDGSKCDCANILDIFALDNVVAIGDPVYPVYNDTNVMIGRTGDADEKGYYKGIVYMP
CTEANGFIPSLPTEKVDIIYLCFPNNPTGTVATKAELKKWVDYANANDAVIFFDAAYEAFITDPAIPHSIYEIEGAKKCA
IEFRSFSKTAGFTGVRCGLVVVPEEVMGTTPTGEKYSFNKLWLRRTTTKFNGASYPVQKAAAAVYSDEGWKQNKEIIDYY
MENARIIREGLAAAGLTVYGGVNAPYIWLKTPGGMSSWDFFDKLLTECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIEA
VERIKKNLK

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=353, Percent_Identity=26.9121813031161, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45135; Mature: 45004

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKINDNYLKLKAGYLFPEIGRRVREFSAANPEAKVIRLGIGDVTRPLAPAIIKAFHDAV
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
DDLATIDNFAGYGPEQGYDWLINAIIEKSYKPLGVSLKTEEMFISDGSKCDCANILDIFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHH
LDNVVAIGDPVYPVYNDTNVMIGRTGDADEKGYYKGIVYMPCTEANGFIPSLPTEKVDII
HCCEEEECCCCCEEECCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YLCFPNNPTGTVATKAELKKWVDYANANDAVIFFDAAYEAFITDPAIPHSIYEIEGAKKC
EEEECCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCHHCCCCCCCCCEEEECCCHHH
AIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTPTGEKYSFNKLWLRRTTTKFNGASYPVQK
HHHHHHHHCCCCCCCEEEEEEEECHHHHCCCCCCCCEECCEEEEEEECCCCCCCCCCHHH
AAAAVYSDEGWKQNKEIIDYYMENARIIREGLAAAGLTVYGGVNAPYIWLKTPGGMSSWD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLTECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIEAVERIKKNLK
HHHHHHHHCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKINDNYLKLKAGYLFPEIGRRVREFSAANPEAKVIRLGIGDVTRPLAPAIIKAFHDAV
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
DDLATIDNFAGYGPEQGYDWLINAIIEKSYKPLGVSLKTEEMFISDGSKCDCANILDIFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHH
LDNVVAIGDPVYPVYNDTNVMIGRTGDADEKGYYKGIVYMPCTEANGFIPSLPTEKVDII
HCCEEEECCCCCEEECCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YLCFPNNPTGTVATKAELKKWVDYANANDAVIFFDAAYEAFITDPAIPHSIYEIEGAKKC
EEEECCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCHHCCCCCCCCCEEEECCCHHH
AIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTPTGEKYSFNKLWLRRTTTKFNGASYPVQK
HHHHHHHHCCCCCCCEEEEEEEECHHHHCCCCCCCCEECCEEEEEEECCCCCCCCCCHHH
AAAAVYSDEGWKQNKEIIDYYMENARIIREGLAAAGLTVYGGVNAPYIWLKTPGGMSSWD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLTECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIEAVERIKKNLK
HHHHHHHHCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA