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The map label for this gene is 78221262

Identifier: 78221262

GI number: 78221262

Start: 44149

End: 45276

Strand: Reverse

Name: 78221262

Synonym: Gmet_0034

Alternate gene names: NA

Gene position: 45276-44149 (Counterclockwise)

Preceding gene: 78221264

Following gene: 78221252

Centisome position: 1.13

GC content: 63.03

Gene sequence:

>1128_bases
GTGAACCTCTTTCTGCTCGTCTTTTTCCTGGTCTACGGCGGCACTCACGCCTATTTCTTCGTCAAGGCGCGGGGGGCCTT
CGGCTTCGGCCCATCCATAGGCACCCTCCTCGCTTTTTTCCTGGCGCTCATGGCCATCGCGCCGGTCCTCGTCCGTATCA
CCGAGCGGCAGGGGTGGGAATTCACAGCCTGCTTCCTGGCCTGGACCGGCTATCTCTGGATGGGCCTCCTCTTTTTCTTC
TTTTCCGCATCTCTTGCCATGGATCTCTTTCACCTCGTTCTCAAGGGGGGAGGAACGCTCCTGCAGCGCGACCCGTCCCT
CCTGATCATCGGAAGAAGGGCCGCCTTCGGCATCGCCGCAGCCTACGCAGTATTGGCATGCCTGTCGAGCTACATGGAGG
CACGACACATCAGGTCCCGGCGGATCGTTATCCCCACCACGAAACTTCCCGCCACGATCCCGAAGCTGACGATAGCGCAA
ATTTCCGATGTCCATCTGGGTCTGATTGTACGGAAGGAACGGCTTGAGAATATCCTGGCCAGAGTCAGGGAGGCCAGGCC
CGACATCGTCGTCTCGACGGGGGATCTGGTGGACGGCCAGATCAACGACCTGTCGGCTCTGGAGAAACCCCTGGCGGAGC
TCTCGCCCCGGTACGGAAAGTTCGCGGTAACCGGCAACCACGAGGTTTACGTCGGTCTCGACCAGGCCATCGGTTTCACT
CGCAGGGGAGGATTTACGGTCCTGCGGGGGGAGGGGGTGACCGCCGGGGGAGTGGTAAACATCGCCGGGGTCGACGACCC
CGCAACCCCTTCGCCGCCCCATGCCGAACGGAACGCCCTGGCGGGACTTCCCGCCGACCGTTTCACCATCCTTCTCAAGC
ATCGCCCCCGGATCGACGGGGAGACCGTTGGACGCTTCGACCTCCAGCTCTCGGGCCACGTCCACGGCGGCCAACTCTTC
CCCTTCGGGCTCCTGGTCCGTCTCTCCTATCCCTACATGGACGGCTTTTATCGGCTGGCGAACGGGTCAGCCCTCTCCGT
GAGCCGCGGCAGCGGCACCTGGGGTCCGCCGCTCCGTTTCCTGGCCCCCCCCGAGGTTACCATCATCGAGTTGATCCCCT
TCGGCTGA

Upstream 100 bases:

>100_bases
CGAGCAGTCGTGCCCGTCCTGCGACAATCCGGAGCCTTAGGATGCGCGTCGGAGGAACGTCTGTGCCCCATTTCCTTGCC
ACCAGGGAGTAACAACCGTC

Downstream 100 bases:

>100_bases
AGAAGGGGCTAGCCGTTCATCAGGTGCTGCCGTACGCCTTGGCCAGGTCGTTGTCGATGGCGTAGATGCAGACCTCCTTG
GCGCCGTTCTTGGTGTAGCG

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNLFLLVFFLVYGGTHAYFFVKARGAFGFGPSIGTLLAFFLALMAIAPVLVRITERQGWEFTACFLAWTGYLWMGLLFFF
FSASLAMDLFHLVLKGGGTLLQRDPSLLIIGRRAAFGIAAAYAVLACLSSYMEARHIRSRRIVIPTTKLPATIPKLTIAQ
ISDVHLGLIVRKERLENILARVREARPDIVVSTGDLVDGQINDLSALEKPLAELSPRYGKFAVTGNHEVYVGLDQAIGFT
RRGGFTVLRGEGVTAGGVVNIAGVDDPATPSPPHAERNALAGLPADRFTILLKHRPRIDGETVGRFDLQLSGHVHGGQLF
PFGLLVRLSYPYMDGFYRLANGSALSVSRGSGTWGPPLRFLAPPEVTIIELIPFG

Sequences:

>Translated_375_residues
MNLFLLVFFLVYGGTHAYFFVKARGAFGFGPSIGTLLAFFLALMAIAPVLVRITERQGWEFTACFLAWTGYLWMGLLFFF
FSASLAMDLFHLVLKGGGTLLQRDPSLLIIGRRAAFGIAAAYAVLACLSSYMEARHIRSRRIVIPTTKLPATIPKLTIAQ
ISDVHLGLIVRKERLENILARVREARPDIVVSTGDLVDGQINDLSALEKPLAELSPRYGKFAVTGNHEVYVGLDQAIGFT
RRGGFTVLRGEGVTAGGVVNIAGVDDPATPSPPHAERNALAGLPADRFTILLKHRPRIDGETVGRFDLQLSGHVHGGQLF
PFGLLVRLSYPYMDGFYRLANGSALSVSRGSGTWGPPLRFLAPPEVTIIELIPFG
>Mature_375_residues
MNLFLLVFFLVYGGTHAYFFVKARGAFGFGPSIGTLLAFFLALMAIAPVLVRITERQGWEFTACFLAWTGYLWMGLLFFF
FSASLAMDLFHLVLKGGGTLLQRDPSLLIIGRRAAFGIAAAYAVLACLSSYMEARHIRSRRIVIPTTKLPATIPKLTIAQ
ISDVHLGLIVRKERLENILARVREARPDIVVSTGDLVDGQINDLSALEKPLAELSPRYGKFAVTGNHEVYVGLDQAIGFT
RRGGFTVLRGEGVTAGGVVNIAGVDDPATPSPPHAERNALAGLPADRFTILLKHRPRIDGETVGRFDLQLSGHVHGGQLF
PFGLLVRLSYPYMDGFYRLANGSALSVSRGSGTWGPPLRFLAPPEVTIIELIPFG

Specific function: Unknown

COG id: COG1408

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

Organism=Homo sapiens, GI210031196, Length=327, Percent_Identity=29.0519877675841, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI210031210, Length=286, Percent_Identity=30.0699300699301, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115535030, Length=248, Percent_Identity=31.0483870967742, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115535028, Length=248, Percent_Identity=31.0483870967742, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71996034, Length=278, Percent_Identity=28.0575539568345, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 40855; Mature: 40855

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFLLVFFLVYGGTHAYFFVKARGAFGFGPSIGTLLAFFLALMAIAPVLVRITERQGWE
CHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FTACFLAWTGYLWMGLLFFFFSASLAMDLFHLVLKGGGTLLQRDPSLLIIGRRAAFGIAA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECHHHHHHHH
AYAVLACLSSYMEARHIRSRRIVIPTTKLPATIPKLTIAQISDVHLGLIVRKERLENILA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEHHHCCCCEEHEEEHHHHHHHHH
RVREARPDIVVSTGDLVDGQINDLSALEKPLAELSPRYGKFAVTGNHEVYVGLDQAIGFT
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHCCEE
RRGGFTVLRGEGVTAGGVVNIAGVDDPATPSPPHAERNALAGLPADRFTILLKHRPRIDG
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCC
ETVGRFDLQLSGHVHGGQLFPFGLLVRLSYPYMDGFYRLANGSALSVSRGSGTWGPPLRF
CCCCEEEEEEECEECCCCCCHHEEEEEECCCHHCCEEEECCCCEEEEECCCCCCCCCCEE
LAPPEVTIIELIPFG
CCCCCEEEEEEEECC
>Mature Secondary Structure
MNLFLLVFFLVYGGTHAYFFVKARGAFGFGPSIGTLLAFFLALMAIAPVLVRITERQGWE
CHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FTACFLAWTGYLWMGLLFFFFSASLAMDLFHLVLKGGGTLLQRDPSLLIIGRRAAFGIAA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECHHHHHHHH
AYAVLACLSSYMEARHIRSRRIVIPTTKLPATIPKLTIAQISDVHLGLIVRKERLENILA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEHHHCCCCEEHEEEHHHHHHHHH
RVREARPDIVVSTGDLVDGQINDLSALEKPLAELSPRYGKFAVTGNHEVYVGLDQAIGFT
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHCCEE
RRGGFTVLRGEGVTAGGVVNIAGVDDPATPSPPHAERNALAGLPADRFTILLKHRPRIDG
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCC
ETVGRFDLQLSGHVHGGQLFPFGLLVRLSYPYMDGFYRLANGSALSVSRGSGTWGPPLRF
CCCCEEEEEEECEECCCCCCHHEEEEEECCCHHCCEEEECCCCEEEEECCCCCCCCCCEE
LAPPEVTIIELIPFG
CCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]