Click here to switch to the map view.

The map label for this gene is feoB1 [H]

Identifier: 78189882

GI number: 78189882

Start: 2460579

End: 2462717

Strand: Reverse

Name: feoB1 [H]

Synonym: Cag_1929

Alternate gene names: 78189882

Gene position: 2462717-2460579 (Counterclockwise)

Preceding gene: 78189883

Following gene: 78189873

Centisome position: 95.75

GC content: 46.14

Gene sequence:

>2139_bases
ATGACTGATGTAAAAGAGATTCGGGTGGCGTTAGCGGGCAATCCCAATTGTGGTAAAACATCTCTGTTTAATGTGCTAAC
GGGCGCTAATCAGCGAGTTGGCAATTTTGCGGGCGTAACGGTTGAAAAGCATGAGGGCTACCTTGAGCATAAGGGGTACA
AAATTACGGTGGTTGATTTGCCCGGTATTTATTCGCTTACCCCCTATTCGCCCGAAGAGATTGTAACGCGCGAGTACCTT
ATTGGCGAAACCCCTGATGTGGTGGTGAATGTGGTTGAAGGTCCAAACCTTGAGCGCAATTTGCTACTCACAACGCAGCT
TATGGAGCTTGAGGTGGATTTTTTAGTTGCCCTCAATATGATGGATGAGGTTGAAGCGAAAGGTATTGTGATTGAGGAAA
AGCAATTGCAGGTGCTGCTTGGTTGCCACATTATTCCTGTTTCGGCTCGTAAAAAAAGCGGCATTGATTCTTTGCTTGAT
CACATTGTGCGCGTTTATCAAAAAAATATCACCATTCAAAAAAATAAGCTCTTTTTTCGTCCTGAGCTTGAGGAGCGTGT
TGAAGCGCTTGCCACCATTCTTGCTCGTCAGCCTGAGCTAAGCACCTATCATCCACGCTGGCTTGCTACCAAGTTGCTTG
AAAATGATCGCGTTGTTTATCACGAAGTGCAAAGCTATCCCGTATGGCTCAAAGTGGAGCGATTGTTGCAAGAAGCTATG
CAAGCTACGGAGCGACTATTTGAGGCTGATCCCGAATTGCTTATTACCGAAGATCGCCATGCCTTTATTCGTGGCGCTAT
GCAGGAGTGTGTTCGTTATCCTACCGTCAAAGGCAAAAGTGTTACCGATTACCTTGACCACATTGTACTGAACCGTGTGC
TGGGTTTGCCCATTTTTTTGTTGGTCGTGTGGGCAATTTTTCAACTTACCTTTACGTTGGGTTCGCCTTTAATGGATGGT
TTAGAGGCATTGTTTGCTCTGCTTGGTGAAGCCATTCAGCCATACTTAACCAATAAGATGCTCCGCTCCATTGTGCTCGA
TGGTATTCTTGCTGGAGTTGGTGGTGTCTTAGTTTTTCTGCCAAACATTGTGCTGCTTTTTCTTGGGCTTTCATTTCTTG
AAGCCTCAGGTTACATGGCGCGTGCAGCTTTTGTGATTGATCGTGTGATGCACCGCTTTGGATTGCATGGTAAATCGTTT
ATTCCGCTGATAACTGGTTTTGGTTGCTCCATTCCTGCTATGATGGCAACACGCACGCTTAAAAGTCATAGTGATCGCTT
AGCAACCCTGATGATTATTCCCTTTATGAGTTGCGGAGCAAAATTGCCCGTTTACGTACTCCTTACGGCAGCTTTTTTCC
CGCCCGAAATGGCAGCCAATGTTATGTTTGGCATTTACATGTTTGGAGTTTTTATAGGGCTTTTAACGGCATTAGTGATG
AAGTCCACGGTGCTGCAAAGCGATTCCGAGCCATTTGTAATGGAGTTGCCGCCTTATCGCTGGCCTACTTTTTCGTCGGT
GTTCTTTCAGGCAAAAATTAAAGCCTTCATGTATTTAAAGAAGGCAGGAACGCTTATTCTTGGGGCAGTTGTCCTTATTT
GGGTGGTCAGCAATTATCCAAAAAGTGCCGCTTTGGAGCAGCAATTGGCTACCGAATCAGCACGCATTGAAGCGTCAACT
ATAGGTGCAGAGGCAAAAGCGACGGAGTTACAAACGCTTGAGGCTGCCATTACCTCACAACAGCTTGAATATTCCATAGC
AGGCAGAGTTGGCAAAGTAATTGAGCCACTTATTAAGCCACTTGGCTTTGATTGGCGCATTGGCATTGCGCTTGTTACAG
GGATTGCCGCCAAAGAGGTGGTGGTTTCAACGCTTGGCACCATTTACTCGCTTGGCGATAGTGAAGATGGTGCCGCAGAA
TTATCAGCCGTGTTGGCGCGTGATCCTGCCTTTAACAAAGCAACAGCATTAAGCTTGATGGTTTTTGTACTGCTTTACAT
TCCTTGCGTTGCCGCTATTGGCGTGATGAAAAAAGAGGTTGGTCGGTGGAAGCCCGTTGTGCTTTATGGCACTTACTCTA
TTGCTGTTGCGTGGGTGATGGCGTTTTTAACCTACCGCATAGCGTTAATGGTGGGGTGA

Upstream 100 bases:

>100_bases
CCTATGGAAATTGCCTTTAAAGGGCTCCATTTAGCGCTTCGTAAAAGTGAAGCGCAAGAAATTTTTGTTGTAAAACATTA
ATGCCGTTAAGGGGTGTTGC

Downstream 100 bases:

>100_bases
GAAAAAAGCTCAAGCTATTTTTTCGACTTCATACATGAAATGATGAGAACAGCTCGCAGCGCCAATAAAATCAAGGAAGA
TTTTATTGGCGCATCAAAGG

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MTDVKEIRVALAGNPNCGKTSLFNVLTGANQRVGNFAGVTVEKHEGYLEHKGYKITVVDLPGIYSLTPYSPEEIVTREYL
IGETPDVVVNVVEGPNLERNLLLTTQLMELEVDFLVALNMMDEVEAKGIVIEEKQLQVLLGCHIIPVSARKKSGIDSLLD
HIVRVYQKNITIQKNKLFFRPELEERVEALATILARQPELSTYHPRWLATKLLENDRVVYHEVQSYPVWLKVERLLQEAM
QATERLFEADPELLITEDRHAFIRGAMQECVRYPTVKGKSVTDYLDHIVLNRVLGLPIFLLVVWAIFQLTFTLGSPLMDG
LEALFALLGEAIQPYLTNKMLRSIVLDGILAGVGGVLVFLPNIVLLFLGLSFLEASGYMARAAFVIDRVMHRFGLHGKSF
IPLITGFGCSIPAMMATRTLKSHSDRLATLMIIPFMSCGAKLPVYVLLTAAFFPPEMAANVMFGIYMFGVFIGLLTALVM
KSTVLQSDSEPFVMELPPYRWPTFSSVFFQAKIKAFMYLKKAGTLILGAVVLIWVVSNYPKSAALEQQLATESARIEAST
IGAEAKATELQTLEAAITSQQLEYSIAGRVGKVIEPLIKPLGFDWRIGIALVTGIAAKEVVVSTLGTIYSLGDSEDGAAE
LSAVLARDPAFNKATALSLMVFVLLYIPCVAAIGVMKKEVGRWKPVVLYGTYSIAVAWVMAFLTYRIALMVG

Sequences:

>Translated_712_residues
MTDVKEIRVALAGNPNCGKTSLFNVLTGANQRVGNFAGVTVEKHEGYLEHKGYKITVVDLPGIYSLTPYSPEEIVTREYL
IGETPDVVVNVVEGPNLERNLLLTTQLMELEVDFLVALNMMDEVEAKGIVIEEKQLQVLLGCHIIPVSARKKSGIDSLLD
HIVRVYQKNITIQKNKLFFRPELEERVEALATILARQPELSTYHPRWLATKLLENDRVVYHEVQSYPVWLKVERLLQEAM
QATERLFEADPELLITEDRHAFIRGAMQECVRYPTVKGKSVTDYLDHIVLNRVLGLPIFLLVVWAIFQLTFTLGSPLMDG
LEALFALLGEAIQPYLTNKMLRSIVLDGILAGVGGVLVFLPNIVLLFLGLSFLEASGYMARAAFVIDRVMHRFGLHGKSF
IPLITGFGCSIPAMMATRTLKSHSDRLATLMIIPFMSCGAKLPVYVLLTAAFFPPEMAANVMFGIYMFGVFIGLLTALVM
KSTVLQSDSEPFVMELPPYRWPTFSSVFFQAKIKAFMYLKKAGTLILGAVVLIWVVSNYPKSAALEQQLATESARIEAST
IGAEAKATELQTLEAAITSQQLEYSIAGRVGKVIEPLIKPLGFDWRIGIALVTGIAAKEVVVSTLGTIYSLGDSEDGAAE
LSAVLARDPAFNKATALSLMVFVLLYIPCVAAIGVMKKEVGRWKPVVLYGTYSIAVAWVMAFLTYRIALMVG
>Mature_711_residues
TDVKEIRVALAGNPNCGKTSLFNVLTGANQRVGNFAGVTVEKHEGYLEHKGYKITVVDLPGIYSLTPYSPEEIVTREYLI
GETPDVVVNVVEGPNLERNLLLTTQLMELEVDFLVALNMMDEVEAKGIVIEEKQLQVLLGCHIIPVSARKKSGIDSLLDH
IVRVYQKNITIQKNKLFFRPELEERVEALATILARQPELSTYHPRWLATKLLENDRVVYHEVQSYPVWLKVERLLQEAMQ
ATERLFEADPELLITEDRHAFIRGAMQECVRYPTVKGKSVTDYLDHIVLNRVLGLPIFLLVVWAIFQLTFTLGSPLMDGL
EALFALLGEAIQPYLTNKMLRSIVLDGILAGVGGVLVFLPNIVLLFLGLSFLEASGYMARAAFVIDRVMHRFGLHGKSFI
PLITGFGCSIPAMMATRTLKSHSDRLATLMIIPFMSCGAKLPVYVLLTAAFFPPEMAANVMFGIYMFGVFIGLLTALVMK
STVLQSDSEPFVMELPPYRWPTFSSVFFQAKIKAFMYLKKAGTLILGAVVLIWVVSNYPKSAALEQQLATESARIEASTI
GAEAKATELQTLEAAITSQQLEYSIAGRVGKVIEPLIKPLGFDWRIGIALVTGIAAKEVVVSTLGTIYSLGDSEDGAAEL
SAVLARDPAFNKATALSLMVFVLLYIPCVAAIGVMKKEVGRWKPVVLYGTYSIAVAWVMAFLTYRIALMVG

Specific function: Fe(2+) uptake system, probably driven by GTP [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=764, Percent_Identity=34.6858638743456, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF04023 FeoA; PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 78696; Mature: 78565

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVKEIRVALAGNPNCGKTSLFNVLTGANQRVGNFAGVTVEKHEGYLEHKGYKITVVDL
CCCHHHHHEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHCCCCEEEEEEEC
PGIYSLTPYSPEEIVTREYLIGETPDVVVNVVEGPNLERNLLLTTQLMELEVDFLVALNM
CCCEECCCCCHHHHHHHHHHCCCCCHHEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
MDEVEAKGIVIEEKQLQVLLGCHIIPVSARKKSGIDSLLDHIVRVYQKNITIQKNKLFFR
HHHHHHCCEEEEHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEC
PELEERVEALATILARQPELSTYHPRWLATKLLENDRVVYHEVQSYPVWLKVERLLQEAM
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHHH
QATERLFEADPELLITEDRHAFIRGAMQECVRYPTVKGKSVTDYLDHIVLNRVLGLPIFL
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVVWAIFQLTFTLGSPLMDGLEALFALLGEAIQPYLTNKMLRSIVLDGILAGVGGVLVFL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNIVLLFLGLSFLEASGYMARAAFVIDRVMHRFGLHGKSFIPLITGFGCSIPAMMATRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHH
KSHSDRLATLMIIPFMSCGAKLPVYVLLTAAFFPPEMAANVMFGIYMFGVFIGLLTALVM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KSTVLQSDSEPFVMELPPYRWPTFSSVFFQAKIKAFMYLKKAGTLILGAVVLIWVVSNYP
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSAALEQQLATESARIEASTIGAEAKATELQTLEAAITSQQLEYSIAGRVGKVIEPLIKP
CHHHHHHHHHHHHHCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFDWRIGIALVTGIAAKEVVVSTLGTIYSLGDSEDGAAELSAVLARDPAFNKATALSLM
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
VFVLLYIPCVAAIGVMKKEVGRWKPVVLYGTYSIAVAWVMAFLTYRIALMVG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDVKEIRVALAGNPNCGKTSLFNVLTGANQRVGNFAGVTVEKHEGYLEHKGYKITVVDL
CCHHHHHEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHCCCCEEEEEEEC
PGIYSLTPYSPEEIVTREYLIGETPDVVVNVVEGPNLERNLLLTTQLMELEVDFLVALNM
CCCEECCCCCHHHHHHHHHHCCCCCHHEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
MDEVEAKGIVIEEKQLQVLLGCHIIPVSARKKSGIDSLLDHIVRVYQKNITIQKNKLFFR
HHHHHHCCEEEEHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEC
PELEERVEALATILARQPELSTYHPRWLATKLLENDRVVYHEVQSYPVWLKVERLLQEAM
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHHH
QATERLFEADPELLITEDRHAFIRGAMQECVRYPTVKGKSVTDYLDHIVLNRVLGLPIFL
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVVWAIFQLTFTLGSPLMDGLEALFALLGEAIQPYLTNKMLRSIVLDGILAGVGGVLVFL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNIVLLFLGLSFLEASGYMARAAFVIDRVMHRFGLHGKSFIPLITGFGCSIPAMMATRTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHH
KSHSDRLATLMIIPFMSCGAKLPVYVLLTAAFFPPEMAANVMFGIYMFGVFIGLLTALVM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KSTVLQSDSEPFVMELPPYRWPTFSSVFFQAKIKAFMYLKKAGTLILGAVVLIWVVSNYP
HHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSAALEQQLATESARIEASTIGAEAKATELQTLEAAITSQQLEYSIAGRVGKVIEPLIKP
CHHHHHHHHHHHHHCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFDWRIGIALVTGIAAKEVVVSTLGTIYSLGDSEDGAAELSAVLARDPAFNKATALSLM
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
VFVLLYIPCVAAIGVMKKEVGRWKPVVLYGTYSIAVAWVMAFLTYRIALMVG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]