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The map label for this gene is crtI [H]

Identifier: 78189843

GI number: 78189843

Start: 2399583

End: 2401100

Strand: Reverse

Name: crtI [H]

Synonym: Cag_1888

Alternate gene names: 78189843

Gene position: 2401100-2399583 (Counterclockwise)

Preceding gene: 78189853

Following gene: 78189837

Centisome position: 93.35

GC content: 49.54

Gene sequence:

>1518_bases
ATGGCAGATAAAAGAGCTGACGTTATTGTGATTGGGGCAGGCATTGGTGGCTTAACTACCGCCGCCTTGCTTCAAGAGAG
GGGAATTCAAACCGTGGTGTTTGAAAAAAATCGCTATGCTGGTGGCAGTTGCTCGGCGTTTCGCCGCGAAGGCTACACCT
TTGATGCTGGGGCATCGGTTTTTTATGGTTTTGGCGATAATGCTTCAAGCGGAACGCTTAATTTACATACTCGCATTTTT
CGCAAGTTTGGGATTAAGGTGGCAACGGTGCCCGATTCTGTGCAAATTCACTACCATCTTCCCAATGGATTTTCGGTAGC
CGCAAGCCATAATCGGCAGCAATTTTTAGCTGCGCTGAAAGCCCGTTTTCCGCATGAAGCTGAGGGAATTGAGCGCTTTT
ACGAGGAGCTAACAGCCGTCTGCGATATTTTACGCGCTATGCCTGCTGGCTCGTTAGAAGATGTTGTTCACTTAGCCTCA
GTTGGCGCTGCTCATCCGTTAAAAACTGTTGCATTGGCGCTGAAAAGTTTTCGCTCCATGGGCAAAACAGCTCGCCGCTA
CATTCGAGATGAAGAGCTGCTCCGCTTTATTGACATTGAAGCTTATTCGTGGGCGGTGCAGGATGCTACGGCAACACCGC
TTGTGAATGCAGGCATCTGCCTTGCCGATCGCCATTATGGTGGCATTAACTATCCCATCGGCGGTTCAGGCGCAATTCCC
GAAGGACTTTGCAAAGCCTTTCAGCAACACGGTGGTACGCTTAACTATCAAGCTGAGGTGGTAGAAATTCTCTTGGAAGC
GGGTGAAGCGCGAGGTGTGCGGTTAGCGGATGGCACGGTGCATTATGCCAAAGTGGTTATTAGTAATGCAACCATTTGGG
ACACCTTTAATCGGATGGTAAAGGATGTGCGTTACCGTGTTGAGGAGGATCGCTTTTTGCGGGCACCAAGTTGGTTTCAG
CTTTTTCTTGGTGTGGATAGCCGTGTAATTCCAGAAGGCTTTAACGTTCACCATATTATTGTGGATAATTGGCAAAGTTA
CCAGCAGCTTGGCGGCACTCTTTATTTTTCGGCTCCCACCATTCTTGATCCATCATTAGCACCTGCAGGGCATCATATTA
TTCATGCTTTTGTTACCGATGAGGTTGCATGTTGGAGCAACTACGAGCGTGGTAGTAGCGCCTACCGTGCAGCCAAAGAG
GAAAAAGCAGCCGCTCTTATTGCTCGCATTGAGCGCATTGTGCCTGAGCTTTCGTCGGCGATTAAGCTGAAAGTGCTTGC
TACGCCGCTCACGCATGAACGCTACCTCAATCGTTATAAAGGCTCGTATGGAGCACTGTTAAAGCCCGGTCAAACCATTT
TGCAAAAGCCACAAAACACAACGCCCGTGCGCAATTTATATGCGGTGGGCGATAGTACTTTTCCCGGGCAGGGAGTAATT
GCGGTTACCTATTCGGGTGTTTCGTGCGCTTCGTATGTGGCGCGCCGTTTTGGCAAACCGCTTGAGGAGTTGGGGTAG

Upstream 100 bases:

>100_bases
GTTAAATTGTAATGGATGCTTCGCTTCGCTCAGCATGACAGAAAGAACTTGACATGACAGTAGCACAAAGCGTTTCTTAT
GTAAATCCGAACTAAAAAAT

Downstream 100 bases:

>100_bases
AAGTGGGGGGGAGGGAGGTGAAGGTACCAATATCCATGATTTTGGTGGGTGCGTTACCTATGAAGTAATTCTCTCTATCC
TAAGGGCACCTCTAAAAATC

Product: carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MADKRADVIVIGAGIGGLTTAALLQERGIQTVVFEKNRYAGGSCSAFRREGYTFDAGASVFYGFGDNASSGTLNLHTRIF
RKFGIKVATVPDSVQIHYHLPNGFSVAASHNRQQFLAALKARFPHEAEGIERFYEELTAVCDILRAMPAGSLEDVVHLAS
VGAAHPLKTVALALKSFRSMGKTARRYIRDEELLRFIDIEAYSWAVQDATATPLVNAGICLADRHYGGINYPIGGSGAIP
EGLCKAFQQHGGTLNYQAEVVEILLEAGEARGVRLADGTVHYAKVVISNATIWDTFNRMVKDVRYRVEEDRFLRAPSWFQ
LFLGVDSRVIPEGFNVHHIIVDNWQSYQQLGGTLYFSAPTILDPSLAPAGHHIIHAFVTDEVACWSNYERGSSAYRAAKE
EKAAALIARIERIVPELSSAIKLKVLATPLTHERYLNRYKGSYGALLKPGQTILQKPQNTTPVRNLYAVGDSTFPGQGVI
AVTYSGVSCASYVARRFGKPLEELG

Sequences:

>Translated_505_residues
MADKRADVIVIGAGIGGLTTAALLQERGIQTVVFEKNRYAGGSCSAFRREGYTFDAGASVFYGFGDNASSGTLNLHTRIF
RKFGIKVATVPDSVQIHYHLPNGFSVAASHNRQQFLAALKARFPHEAEGIERFYEELTAVCDILRAMPAGSLEDVVHLAS
VGAAHPLKTVALALKSFRSMGKTARRYIRDEELLRFIDIEAYSWAVQDATATPLVNAGICLADRHYGGINYPIGGSGAIP
EGLCKAFQQHGGTLNYQAEVVEILLEAGEARGVRLADGTVHYAKVVISNATIWDTFNRMVKDVRYRVEEDRFLRAPSWFQ
LFLGVDSRVIPEGFNVHHIIVDNWQSYQQLGGTLYFSAPTILDPSLAPAGHHIIHAFVTDEVACWSNYERGSSAYRAAKE
EKAAALIARIERIVPELSSAIKLKVLATPLTHERYLNRYKGSYGALLKPGQTILQKPQNTTPVRNLYAVGDSTFPGQGVI
AVTYSGVSCASYVARRFGKPLEELG
>Mature_504_residues
ADKRADVIVIGAGIGGLTTAALLQERGIQTVVFEKNRYAGGSCSAFRREGYTFDAGASVFYGFGDNASSGTLNLHTRIFR
KFGIKVATVPDSVQIHYHLPNGFSVAASHNRQQFLAALKARFPHEAEGIERFYEELTAVCDILRAMPAGSLEDVVHLASV
GAAHPLKTVALALKSFRSMGKTARRYIRDEELLRFIDIEAYSWAVQDATATPLVNAGICLADRHYGGINYPIGGSGAIPE
GLCKAFQQHGGTLNYQAEVVEILLEAGEARGVRLADGTVHYAKVVISNATIWDTFNRMVKDVRYRVEEDRFLRAPSWFQL
FLGVDSRVIPEGFNVHHIIVDNWQSYQQLGGTLYFSAPTILDPSLAPAGHHIIHAFVTDEVACWSNYERGSSAYRAAKEE
KAAALIARIERIVPELSSAIKLKVLATPLTHERYLNRYKGSYGALLKPGQTILQKPQNTTPVRNLYAVGDSTFPGQGVIA
VTYSGVSCASYVARRFGKPLEELG

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=535, Percent_Identity=22.6168224299065, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540238, Length=532, Percent_Identity=23.1203007518797, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 55314; Mature: 55182

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKRADVIVIGAGIGGLTTAALLQERGIQTVVFEKNRYAGGSCSAFRREGYTFDAGASV
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCEEECCCCE
FYGFGDNASSGTLNLHTRIFRKFGIKVATVPDSVQIHYHLPNGFSVAASHNRQQFLAALK
EEECCCCCCCCEEEHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHH
ARFPHEAEGIERFYEELTAVCDILRAMPAGSLEDVVHLASVGAAHPLKTVALALKSFRSM
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GKTARRYIRDEELLRFIDIEAYSWAVQDATATPLVNAGICLADRHYGGINYPIGGSGAIP
HHHHHHHHCHHHHHHHHCCHHHEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
EGLCKAFQQHGGTLNYQAEVVEILLEAGEARGVRLADGTVHYAKVVISNATIWDTFNRMV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHH
KDVRYRVEEDRFLRAPSWFQLFLGVDSRVIPEGFNVHHIIVDNWQSYQQLGGTLYFSAPT
HHHHHHHCCCCEECCCHHHHHEECCCCCCCCCCCCEEEEEECCHHHHHHCCCEEEECCCC
ILDPSLAPAGHHIIHAFVTDEVACWSNYERGSSAYRAAKEEKAAALIARIERIVPELSSA
CCCCCCCCCCCCEEEEEHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKLKVLATPLTHERYLNRYKGSYGALLKPGQTILQKPQNTTPVRNLYAVGDSTFPGQGVI
EEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHEEEECCCCCCCCCEE
AVTYSGVSCASYVARRFGKPLEELG
EEEECCCHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure 
ADKRADVIVIGAGIGGLTTAALLQERGIQTVVFEKNRYAGGSCSAFRREGYTFDAGASV
CCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCEEECCCCE
FYGFGDNASSGTLNLHTRIFRKFGIKVATVPDSVQIHYHLPNGFSVAASHNRQQFLAALK
EEECCCCCCCCEEEHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHH
ARFPHEAEGIERFYEELTAVCDILRAMPAGSLEDVVHLASVGAAHPLKTVALALKSFRSM
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GKTARRYIRDEELLRFIDIEAYSWAVQDATATPLVNAGICLADRHYGGINYPIGGSGAIP
HHHHHHHHCHHHHHHHHCCHHHEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
EGLCKAFQQHGGTLNYQAEVVEILLEAGEARGVRLADGTVHYAKVVISNATIWDTFNRMV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHH
KDVRYRVEEDRFLRAPSWFQLFLGVDSRVIPEGFNVHHIIVDNWQSYQQLGGTLYFSAPT
HHHHHHHCCCCEECCCHHHHHEECCCCCCCCCCCCEEEEEECCHHHHHHCCCEEEECCCC
ILDPSLAPAGHHIIHAFVTDEVACWSNYERGSSAYRAAKEEKAAALIARIERIVPELSSA
CCCCCCCCCCCCEEEEEHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKLKVLATPLTHERYLNRYKGSYGALLKPGQTILQKPQNTTPVRNLYAVGDSTFPGQGVI
EEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHEEEECCCCCCCCCEE
AVTYSGVSCASYVARRFGKPLEELG
EEEECCCHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]