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The map label for this gene is menC [H]

Identifier: 78189674

GI number: 78189674

Start: 2232123

End: 2233214

Strand: Reverse

Name: menC [H]

Synonym: Cag_1718

Alternate gene names: 78189674

Gene position: 2233214-2232123 (Counterclockwise)

Preceding gene: 78189675

Following gene: 78189673

Centisome position: 86.83

GC content: 49.91

Gene sequence:

>1092_bases
ATGGAGCTGGAACTTTCTCTTTACCGCTATGCCATCCCTTTTACTGAGCCAATTACTGTGAAGCAGCAACGGCTTGTAAT
GCGGGATGGCTTGGTGCTTGCCCTTACAAGCGCTACAGAAGCGGTAACCGCTTTTGGTGAAATTGCTCCGCTTTTTGGCT
TGCATAGCGAAACGTTGGAGCAAGCTGAAGCCCAGCTTGTAACGCTTTTTGCAACTCCCCACACAACCCTCGCTCGCATT
ATGGAGGCGCAATTCTATCCTTCGGTGCGTACAGGGTTAGAAATGGCGATACACAATTTCACCGCTGCACGTTCAGGTGC
TTTGCCACGCTTTGGCACAACGCCTCATAACGCCGAGCAAGTGCCCGTTAACGCCTTGCTTTTTGGCGCTTCCAACGAAG
TGGTTGAACGAGCCGAGCGGTTGTTTACGGCTGGTTACCGCACCTTTAAACTGAAAGTAAACGCCGCCAACAGCGCAAAT
GCCATAGCAAGTATTCAGGCTCTGCATAGCCGCTTTGGTAACGCTATTGCTTTACGGCTCGATGCCAATCAATCATTTAC
CTTGAATGACGCTATTGCATTTGGCAAAGCACTGCCCGATGGCAGCATTGCCTATATTGAAGAGCCACTGCAAAACGCCG
AGCGCATTGGCGACTTTTATGCTGCAACCGCAATTCCAGCCGCACTTGATGAAACGCTGTGGCAAAATCCTGCATTGCTC
GACATTATTCCCACTAAAGCATTAGCGGCATTAGTGCTTAAACCCAACCGTTTGGGCGGCATTACCGTAGCAGAAAAGTT
TGCTCGTTATGCGGCTGAACGTGGTTTGCTTGCCGTTGTTAGCTCCGCCTTTGAAAGCGGCATAAGCCTTGGTTTTTACG
CATGGCTTGCCGCCTCATGCAACGCCGAACCTGCCGCTTGCGGGCTTGATACAAGTCGCTATTTAGCCTTCGATGTGCTA
ACAACGCCCTTTCCAACCAACACACCTTTGCTTGATGCCGCACAGTGCTACCGCAACAGCTTACAGGTGAATCTTGCAAC
ACTCAAGCCTTGTGCTATGCCTCAAAGTTTTAGAATTTTGATGGAAAATTAA

Upstream 100 bases:

>100_bases
CCACCATGCTTTATTACATGACTGAAGAGGGGCAGGAAGGCAAAAATGCTTTTGTTGAAAAACGTAAACCCAACTTCAAC
AAATTCCCTCGCCGCCCATA

Downstream 100 bases:

>100_bases
CAACTTCAGAACTCTATCGGGTAACGGCAAAACAACCAACAAGTTTTTTTAGGATAAAAAACATGGCAATAACGTTTTTG
CAAATGGCGGAAAAAGTGCT

Product: O-succinylbenzoate-CoA synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MELELSLYRYAIPFTEPITVKQQRLVMRDGLVLALTSATEAVTAFGEIAPLFGLHSETLEQAEAQLVTLFATPHTTLARI
MEAQFYPSVRTGLEMAIHNFTAARSGALPRFGTTPHNAEQVPVNALLFGASNEVVERAERLFTAGYRTFKLKVNAANSAN
AIASIQALHSRFGNAIALRLDANQSFTLNDAIAFGKALPDGSIAYIEEPLQNAERIGDFYAATAIPAALDETLWQNPALL
DIIPTKALAALVLKPNRLGGITVAEKFARYAAERGLLAVVSSAFESGISLGFYAWLAASCNAEPAACGLDTSRYLAFDVL
TTPFPTNTPLLDAAQCYRNSLQVNLATLKPCAMPQSFRILMEN

Sequences:

>Translated_363_residues
MELELSLYRYAIPFTEPITVKQQRLVMRDGLVLALTSATEAVTAFGEIAPLFGLHSETLEQAEAQLVTLFATPHTTLARI
MEAQFYPSVRTGLEMAIHNFTAARSGALPRFGTTPHNAEQVPVNALLFGASNEVVERAERLFTAGYRTFKLKVNAANSAN
AIASIQALHSRFGNAIALRLDANQSFTLNDAIAFGKALPDGSIAYIEEPLQNAERIGDFYAATAIPAALDETLWQNPALL
DIIPTKALAALVLKPNRLGGITVAEKFARYAAERGLLAVVSSAFESGISLGFYAWLAASCNAEPAACGLDTSRYLAFDVL
TTPFPTNTPLLDAAQCYRNSLQVNLATLKPCAMPQSFRILMEN
>Mature_363_residues
MELELSLYRYAIPFTEPITVKQQRLVMRDGLVLALTSATEAVTAFGEIAPLFGLHSETLEQAEAQLVTLFATPHTTLARI
MEAQFYPSVRTGLEMAIHNFTAARSGALPRFGTTPHNAEQVPVNALLFGASNEVVERAERLFTAGYRTFKLKVNAANSAN
AIASIQALHSRFGNAIALRLDANQSFTLNDAIAFGKALPDGSIAYIEEPLQNAERIGDFYAATAIPAALDETLWQNPALL
DIIPTKALAALVLKPNRLGGITVAEKFARYAAERGLLAVVSSAFESGISLGFYAWLAASCNAEPAACGLDTSRYLAFDVL
TTPFPTNTPLLDAAQCYRNSLQVNLATLKPCAMPQSFRILMEN

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=309, Percent_Identity=28.8025889967638, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39230; Mature: 39230

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELELSLYRYAIPFTEPITVKQQRLVMRDGLVLALTSATEAVTAFGEIAPLFGLHSETLE
CCEEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHH
QAEAQLVTLFATPHTTLARIMEAQFYPSVRTGLEMAIHNFTAARSGALPRFGTTPHNAEQ
HHHHEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
VPVNALLFGASNEVVERAERLFTAGYRTFKLKVNAANSANAIASIQALHSRFGNAIALRL
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
DANQSFTLNDAIAFGKALPDGSIAYIEEPLQNAERIGDFYAATAIPAALDETLWQNPALL
ECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DIIPTKALAALVLKPNRLGGITVAEKFARYAAERGLLAVVSSAFESGISLGFYAWLAASC
EEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCC
NAEPAACGLDTSRYLAFDVLTTPFPTNTPLLDAAQCYRNSLQVNLATLKPCAMPQSFRIL
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHEEE
MEN
ECC
>Mature Secondary Structure
MELELSLYRYAIPFTEPITVKQQRLVMRDGLVLALTSATEAVTAFGEIAPLFGLHSETLE
CCEEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHH
QAEAQLVTLFATPHTTLARIMEAQFYPSVRTGLEMAIHNFTAARSGALPRFGTTPHNAEQ
HHHHEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
VPVNALLFGASNEVVERAERLFTAGYRTFKLKVNAANSANAIASIQALHSRFGNAIALRL
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
DANQSFTLNDAIAFGKALPDGSIAYIEEPLQNAERIGDFYAATAIPAALDETLWQNPALL
ECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DIIPTKALAALVLKPNRLGGITVAEKFARYAAERGLLAVVSSAFESGISLGFYAWLAASC
EEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCC
NAEPAACGLDTSRYLAFDVLTTPFPTNTPLLDAAQCYRNSLQVNLATLKPCAMPQSFRIL
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHEEE
MEN
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]