Click here to switch to the map view.

The map label for this gene is infC

Identifier: 78189670

GI number: 78189670

Start: 2226496

End: 2227176

Strand: Reverse

Name: infC

Synonym: Cag_1714

Alternate gene names: 78189670

Gene position: 2227176-2226496 (Counterclockwise)

Preceding gene: 78189671

Following gene: 78189669

Centisome position: 86.59

GC content: 46.11

Gene sequence:

>681_bases
ATGAAGAAACCAAAGGTTACAACGCAAAAACCAAAACTCACCTACCGCGTCAACGAGCAAATTCGTGTGCCAGAGGTTCG
CGTGATTTTTACCGACGGGACACAAAAGGTTATGCCGACCCTTGAAGCAAGGCGAATGGCGGAAGAGCGCAATCAGGACC
TTATTGAAGTGCAGCCAAATGCCGCGCCACCCGTTTGTAAGTTCGATAATCTCGGTAAGCTTCTCTACAAAATGGATAAG
CGTGATAAGGATTTAAAGAAAAAGCAGAAGGCAACAACGCTGAAAGAGTTGCGCTTTCATCCCAATACCGATAAGCACGA
TTTCGATTTTAAAACGGCGCACCTTGAAGAGTTTCTTCGCAAAGGCAACCGCGTAAGGGCGACTATTGTTTTTCTTGGGC
GCTCCATTATCTACAAAGATAAAGGGCTGGAACTTGCCGAACGTTTAACCGAACGCCTCAGCATTGTGAGCAATCGCGAT
GGCGATCCAAAATTCGAGGGCAAAAAGCTCTTTGTTTATTTCGATCCCGATAAAAAGAAAATTGATACCTACGAGCGCAT
TAAAGCGAAAACAAGCCAGCCATTTGTGCCGCTTGCTCCGCTTTCGCCCGAAGACCTTATTGAAGAGCCTGAATTGGAGT
CAGAATCAGACTCAGACGCAGAGCCAGAATCAGACAATTAA

Upstream 100 bases:

>100_bases
TTGCTAATCGCCAGTAAAGAGTGGCAAAGAGGGCATTGTTAACAATGAATTTTGAGTGATGCCCCGCAAGTTTGATACCC
GATAAACAAATTCATAACGA

Downstream 100 bases:

>100_bases
TCCGTGGGTATTTCCACAACATGGTAGCTCTTGCTTGCAAACAAGAGTAAACCTGCTGTTGAAGAAATCAACCCCTTGTT
TTCCCATAAACCATATAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKKPKVTTQKPKLTYRVNEQIRVPEVRVIFTDGTQKVMPTLEARRMAEERNQDLIEVQPNAAPPVCKFDNLGKLLYKMDK
RDKDLKKKQKATTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGLELAERLTERLSIVSNRD
GDPKFEGKKLFVYFDPDKKKIDTYERIKAKTSQPFVPLAPLSPEDLIEEPELESESDSDAEPESDN

Sequences:

>Translated_226_residues
MKKPKVTTQKPKLTYRVNEQIRVPEVRVIFTDGTQKVMPTLEARRMAEERNQDLIEVQPNAAPPVCKFDNLGKLLYKMDK
RDKDLKKKQKATTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGLELAERLTERLSIVSNRD
GDPKFEGKKLFVYFDPDKKKIDTYERIKAKTSQPFVPLAPLSPEDLIEEPELESESDSDAEPESDN
>Mature_226_residues
MKKPKVTTQKPKLTYRVNEQIRVPEVRVIFTDGTQKVMPTLEARRMAEERNQDLIEVQPNAAPPVCKFDNLGKLLYKMDK
RDKDLKKKQKATTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGLELAERLTERLSIVSNRD
GDPKFEGKKLFVYFDPDKKKIDTYERIKAKTSQPFVPLAPLSPEDLIEEPELESESDSDAEPESDN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=178, Percent_Identity=37.0786516853933, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CHLCH (Q3APW0)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_380008.1
- ProteinModelPortal:   Q3APW0
- STRING:   Q3APW0
- GeneID:   3746980
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1714
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   YEAKKES
- ProtClustDB:   PRK00028
- BioCyc:   CCHL340177:CAG_1714-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 26276; Mature: 26276

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPKVTTQKPKLTYRVNEQIRVPEVRVIFTDGTQKVMPTLEARRMAEERNQDLIEVQPN
CCCCCCCCCCCCEEEEECCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCC
AAPPVCKFDNLGKLLYKMDKRDKDLKKKQKATTLKELRFHPNTDKHDFDFKTAHLEEFLR
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
KGNRVRATIVFLGRSIIYKDKGLELAERLTERLSIVSNRDGDPKFEGKKLFVYFDPDKKK
CCCCEEEEEEEECCHHEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCH
IDTYERIKAKTSQPFVPLAPLSPEDLIEEPELESESDSDAEPESDN
HHHHHHHHHHCCCCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKPKVTTQKPKLTYRVNEQIRVPEVRVIFTDGTQKVMPTLEARRMAEERNQDLIEVQPN
CCCCCCCCCCCCEEEEECCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCC
AAPPVCKFDNLGKLLYKMDKRDKDLKKKQKATTLKELRFHPNTDKHDFDFKTAHLEEFLR
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
KGNRVRATIVFLGRSIIYKDKGLELAERLTERLSIVSNRDGDPKFEGKKLFVYFDPDKKK
CCCCEEEEEEEECCHHEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCH
IDTYERIKAKTSQPFVPLAPLSPEDLIEEPELESESDSDAEPESDN
HHHHHHHHHHCCCCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA