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The map label for this gene is ftsK [H]

Identifier: 78189611

GI number: 78189611

Start: 2150796

End: 2152397

Strand: Reverse

Name: ftsK [H]

Synonym: Cag_1654

Alternate gene names: 78189611

Gene position: 2152397-2150796 (Counterclockwise)

Preceding gene: 78189612

Following gene: 78189607

Centisome position: 83.68

GC content: 47.88

Gene sequence:

>1602_bases
TTGCGTGCCGTTCCCCCCGAAATAGTGCCTATTCCCACTTTGCCCGGTGAGCCTGAAATGGTGTTGCATACGGGCGTGCG
CGAAAAAGAGGCTGATCTTGATGAGCGTAAGCTAAAGGTTCACACTAAAGATCGTGATGCCTATCGTTTCCCTTCTATTG
ACTTGTTGGAAAAAGTGCATGATGATGACGAGGCAATTGATGAGCAGCATTTAGCCGAAAGTAAACGTCGCTTGCTTGAA
AAGTTGCGCATTTACAAAATTGAGGTGAAGCGCATTGCCACTACCGTTGGACCTCGTGTAACGCTTTTTGAGCTTGAGCT
TGAACCCGACGTTAAAGTAAGCCGTGTAACCTCGCTTGAAAACGATCTTGCCATGGCGCTTGCGGCGCGTGGCATTCGCA
TTATTGCCCCCATCCCTGGCAAAAATGCAGTGGGTGTTGAAATTCCCAATGCAAAGCCAAAAACCGTATGGCTTCGCTCA
GTGTTACAGGTGGAGAAGTTTAAAAGTAACAACATGATTTTACCGATTGTGTTGGGCAAAACCATTGCCAACGAAGTCTA
TATTGCCGACCTTGCCACCATGCCGCATTTGCTGATTGCGGGTGCTACGGGCGCTGGTAAGTCGGTCTGCATTAACGTGA
TTATTAGCAGCTTACTCTACGCTTGCAGCCCCGATAAAGTGAAGTTTGTCATGGTTGACCCAAAGCGGGTGGAGCTGTTC
CAATATCAGCACTTAAAAAACCACTTTCTCATGCGCTTTCCGGGGATTGAGGAGCAAATTATTACCGATCCCCAAAAAGC
TGTTTTTGCCCTGCGCTGTGTGGTAAAAGAGATGGAAATGCGCTACGAGGCGCTTGAAAAAGGGAGTGTGCGCAACATTG
GCGACTTCAATCGTCGTTATCCCGATGATGCTCTGCCCTATTTGGTGGTGGTTATTGATGAGCTTGCAGATTTAATGATT
ACCGCTGGACGTGAAGTTGAAGAGCCAATTATCCGCATTGCTCAACTTGCCCGTGCGGTTGGCATTCATTTGATTGTGGC
AACGCAGCGTCCTTCGGTGGATGTTATTACGGGCATTATTAAAGCGAACTTTCCTGCTCGTATTGCTTTTCAGGTGGCAA
GCCGCGTGGATTCTCGCACCATTCTTGATGGCTCAGGTGCCGAGCAATTACTTGGCAATGGCGATATGCTTTATCAGCCA
TCAAATCAGCCCAAGCCAATTCGCATTCAAAGCCCTTACGTCTCCTCTTCTGAAGTAGAGGAAATTACCTCCTTTATTGG
TGCGCAACATGCGTTAAAAAATATTTATGTGCTGCCCATGCCCGATGTATCGAAAAATTCCAATATGCAAGGTGGAAGTG
CTCAAGATCGTGATGGGCGCGATGCCATGTTTGAAGAGGCTGCTCGTTTGGTAGTAATGCACCAACAAGCAAGCGTGTCG
CTGTTGCAGCGGCGCTTACGGCTTGGCTTTAGCCGCGCAGGCAGGGTGATGGATCAGCTTGAAGCAAATGGAATTGTAGG
AGAAGCGGATGGAAGCAAATCAAGGGATGTCCTCATTAAAAACGAAGACTCCCTTGAGTTACTCTTGCGGAATTTAGATT
GA

Upstream 100 bases:

>100_bases
TAAAGCTGAGCGTTCACAAAAGCCTCGCTCGGTAAAAACTACGGAGCCACTTGTTTCTACCGTTACGCCCTTTAGTCCTC
TTGATGTTTCGCGCGATGAG

Downstream 100 bases:

>100_bases
GGAGGCTTACACCGACTCAACACGTACAATTTCAGGAATAGCTTTTTTAATTGCTTGTTCCACGCCCGCACGTAACGTAA
GCGTGCTCATTGGGCAGGAG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MRAVPPEIVPIPTLPGEPEMVLHTGVREKEADLDERKLKVHTKDRDAYRFPSIDLLEKVHDDDEAIDEQHLAESKRRLLE
KLRIYKIEVKRIATTVGPRVTLFELELEPDVKVSRVTSLENDLAMALAARGIRIIAPIPGKNAVGVEIPNAKPKTVWLRS
VLQVEKFKSNNMILPIVLGKTIANEVYIADLATMPHLLIAGATGAGKSVCINVIISSLLYACSPDKVKFVMVDPKRVELF
QYQHLKNHFLMRFPGIEEQIITDPQKAVFALRCVVKEMEMRYEALEKGSVRNIGDFNRRYPDDALPYLVVVIDELADLMI
TAGREVEEPIIRIAQLARAVGIHLIVATQRPSVDVITGIIKANFPARIAFQVASRVDSRTILDGSGAEQLLGNGDMLYQP
SNQPKPIRIQSPYVSSSEVEEITSFIGAQHALKNIYVLPMPDVSKNSNMQGGSAQDRDGRDAMFEEAARLVVMHQQASVS
LLQRRLRLGFSRAGRVMDQLEANGIVGEADGSKSRDVLIKNEDSLELLLRNLD

Sequences:

>Translated_533_residues
MRAVPPEIVPIPTLPGEPEMVLHTGVREKEADLDERKLKVHTKDRDAYRFPSIDLLEKVHDDDEAIDEQHLAESKRRLLE
KLRIYKIEVKRIATTVGPRVTLFELELEPDVKVSRVTSLENDLAMALAARGIRIIAPIPGKNAVGVEIPNAKPKTVWLRS
VLQVEKFKSNNMILPIVLGKTIANEVYIADLATMPHLLIAGATGAGKSVCINVIISSLLYACSPDKVKFVMVDPKRVELF
QYQHLKNHFLMRFPGIEEQIITDPQKAVFALRCVVKEMEMRYEALEKGSVRNIGDFNRRYPDDALPYLVVVIDELADLMI
TAGREVEEPIIRIAQLARAVGIHLIVATQRPSVDVITGIIKANFPARIAFQVASRVDSRTILDGSGAEQLLGNGDMLYQP
SNQPKPIRIQSPYVSSSEVEEITSFIGAQHALKNIYVLPMPDVSKNSNMQGGSAQDRDGRDAMFEEAARLVVMHQQASVS
LLQRRLRLGFSRAGRVMDQLEANGIVGEADGSKSRDVLIKNEDSLELLLRNLD
>Mature_533_residues
MRAVPPEIVPIPTLPGEPEMVLHTGVREKEADLDERKLKVHTKDRDAYRFPSIDLLEKVHDDDEAIDEQHLAESKRRLLE
KLRIYKIEVKRIATTVGPRVTLFELELEPDVKVSRVTSLENDLAMALAARGIRIIAPIPGKNAVGVEIPNAKPKTVWLRS
VLQVEKFKSNNMILPIVLGKTIANEVYIADLATMPHLLIAGATGAGKSVCINVIISSLLYACSPDKVKFVMVDPKRVELF
QYQHLKNHFLMRFPGIEEQIITDPQKAVFALRCVVKEMEMRYEALEKGSVRNIGDFNRRYPDDALPYLVVVIDELADLMI
TAGREVEEPIIRIAQLARAVGIHLIVATQRPSVDVITGIIKANFPARIAFQVASRVDSRTILDGSGAEQLLGNGDMLYQP
SNQPKPIRIQSPYVSSSEVEEITSFIGAQHALKNIYVLPMPDVSKNSNMQGGSAQDRDGRDAMFEEAARLVVMHQQASVS
LLQRRLRLGFSRAGRVMDQLEANGIVGEADGSKSRDVLIKNEDSLELLLRNLD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=498, Percent_Identity=42.570281124498, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 59402; Mature: 59402

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVPPEIVPIPTLPGEPEMVLHTGVREKEADLDERKLKVHTKDRDAYRFPSIDLLEKVH
CCCCCCCCEECCCCCCCCCEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
DDDEAIDEQHLAESKRRLLEKLRIYKIEVKRIATTVGPRVTLFELELEPDVKVSRVTSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
NDLAMALAARGIRIIAPIPGKNAVGVEIPNAKPKTVWLRSVLQVEKFKSNNMILPIVLGK
HHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
TIANEVYIADLATMPHLLIAGATGAGKSVCINVIISSLLYACSPDKVKFVMVDPKRVELF
HHHCCEEEEHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHH
QYQHLKNHFLMRFPGIEEQIITDPQKAVFALRCVVKEMEMRYEALEKGSVRNIGDFNRRY
HHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC
PDDALPYLVVVIDELADLMITAGREVEEPIIRIAQLARAVGIHLIVATQRPSVDVITGII
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHH
KANFPARIAFQVASRVDSRTILDGSGAEQLLGNGDMLYQPSNQPKPIRIQSPYVSSSEVE
HCCCCHHHHHHHHHHCCCCEEECCCCHHHHHCCCCEEECCCCCCCCEEEECCCCCHHHHH
EITSFIGAQHALKNIYVLPMPDVSKNSNMQGGSAQDRDGRDAMFEEAARLVVMHQQASVS
HHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECHHHHH
LLQRRLRLGFSRAGRVMDQLEANGIVGEADGSKSRDVLIKNEDSLELLLRNLD
HHHHHHHHCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MRAVPPEIVPIPTLPGEPEMVLHTGVREKEADLDERKLKVHTKDRDAYRFPSIDLLEKVH
CCCCCCCCEECCCCCCCCCEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
DDDEAIDEQHLAESKRRLLEKLRIYKIEVKRIATTVGPRVTLFELELEPDVKVSRVTSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
NDLAMALAARGIRIIAPIPGKNAVGVEIPNAKPKTVWLRSVLQVEKFKSNNMILPIVLGK
HHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
TIANEVYIADLATMPHLLIAGATGAGKSVCINVIISSLLYACSPDKVKFVMVDPKRVELF
HHHCCEEEEHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHH
QYQHLKNHFLMRFPGIEEQIITDPQKAVFALRCVVKEMEMRYEALEKGSVRNIGDFNRRY
HHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC
PDDALPYLVVVIDELADLMITAGREVEEPIIRIAQLARAVGIHLIVATQRPSVDVITGII
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHH
KANFPARIAFQVASRVDSRTILDGSGAEQLLGNGDMLYQPSNQPKPIRIQSPYVSSSEVE
HCCCCHHHHHHHHHHCCCCEEECCCCHHHHHCCCCEEECCCCCCCCEEEECCCCCHHHHH
EITSFIGAQHALKNIYVLPMPDVSKNSNMQGGSAQDRDGRDAMFEEAARLVVMHQQASVS
HHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECHHHHH
LLQRRLRLGFSRAGRVMDQLEANGIVGEADGSKSRDVLIKNEDSLELLLRNLD
HHHHHHHHCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]