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The map label for this gene is moaC/mobA [H]

Identifier: 78189027

GI number: 78189027

Start: 1441377

End: 1442483

Strand: Reverse

Name: moaC/mobA [H]

Synonym: Cag_1060

Alternate gene names: 78189027

Gene position: 1442483-1441377 (Counterclockwise)

Preceding gene: 78189028

Following gene: 78189026

Centisome position: 56.08

GC content: 50.32

Gene sequence:

>1107_bases
ATGACCTTCCACCCCTTTGAGATAGCTTTTTGCGGCTATTCAGGCTCAGGCAAAACCACGTTGCTTACAAAAGTTGTGCG
ATCTTTAGCAGAGCGCTACAGCGTAGCATGTTATAAGCATGGCTGCCACCATTTTTCTCTTGATAAAGAAGGAAAAGATT
CTTGGCTTATGCGGCAGGCTGGCGCTTCAGCCGTTATGATTGGCGATCCTCAGCAGCAAGCGCTGATGGCGGAGCGGGGC
GTTTTTTCTTTAGCGCTTGAGCGCCATGCCTTTGCGTTTGCAGATATGTTGTTGGTTGAGGGGTTAAAGGAGTTGCCGTT
GCCCAAATTGTTGATGATTGATGCTGAGCGGCGTATTGTGAAGCTGTGGCAGCAGGGGAGTATCAGCAATGTGTTGGGCT
TTATTTCGCCCGACGATCCCCAGCATTATACTGATTATGGATTGCCGGTTATGCAGCGCGACAATGTGGAGGCAATAGCT
CATTTTGTTGAGAGCATCTTACTTGAACGGGCAAAAGCGCACTATCCGCTTAATGGCTTATTGCTTGCTGGTGGGCAAAG
TTCTCGTATGGGGAGCGATAAAGCGCTTCTCAGTTATCACGGCGATAATCAGCTTCAGCACACGGCAGCGCTGCTTCGCG
AGGTGTGTTGCAACGTCTATGTTTCATGCCGTCAAGAGCAAGCCGAGCACTATTGCCAATTTGGCATTCCATTGATTACC
GATGCTTATCTTGGCATTGGTCCAATGGGTGGATTGCTTTCGGCACAGCAAGCGCATCCCAATGCCGCATGGTTGGTTAC
AGCGTGCGACATGCCACTGCTCACGCCCAAAACCTTGCAGCAGCTTGCAGAGGAGCGCCAGCCCCTGCGTTTCGCCACAG
CATTTCGCCATCCCCAAACCCAGCGGCTTGAACCGCTTTTTGCAATTTATGAGCCAAAAACACGAATCCCGTTGCTTTTG
CAACATGCTGAAGGCAATAATTCGCTTGCCTCATTTCTTGCAACCGCACGAATTGCCGCGCTTATGCCTGATGCTGCACA
ATCATTGCTGAACATTAACACCCCCGACGAACAAAAGTCGTTTGAGCAAAACCAAGGCAGAGCATGA

Upstream 100 bases:

>100_bases
CACTGTTTATGAAATATGAAAATGTTAAGGAGTCTTATATGGGCTTTCCCGATAATTGGCGTAATAAGCAAATCTGGCAG
TAAGTACTATAAAAATAATC

Downstream 100 bases:

>100_bases
AATTGCACTCGCAACAACCTCGCTTGCAATGGTTGTTGAAGCTATCGCCAAAATATTTGAGCGGTGGGAATGAGTTTCCG
CACAAATCTCCGCCTTGTAA

Product: putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MobA

Products: molybdopterin guanine dinucleotide; pyrophosphate [C]

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdopterin-guanine dinucleotide biosynthesis protein A [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTFHPFEIAFCGYSGSGKTTLLTKVVRSLAERYSVACYKHGCHHFSLDKEGKDSWLMRQAGASAVMIGDPQQQALMAERG
VFSLALERHAFAFADMLLVEGLKELPLPKLLMIDAERRIVKLWQQGSISNVLGFISPDDPQHYTDYGLPVMQRDNVEAIA
HFVESILLERAKAHYPLNGLLLAGGQSSRMGSDKALLSYHGDNQLQHTAALLREVCCNVYVSCRQEQAEHYCQFGIPLIT
DAYLGIGPMGGLLSAQQAHPNAAWLVTACDMPLLTPKTLQQLAEERQPLRFATAFRHPQTQRLEPLFAIYEPKTRIPLLL
QHAEGNNSLASFLATARIAALMPDAAQSLLNINTPDEQKSFEQNQGRA

Sequences:

>Translated_368_residues
MTFHPFEIAFCGYSGSGKTTLLTKVVRSLAERYSVACYKHGCHHFSLDKEGKDSWLMRQAGASAVMIGDPQQQALMAERG
VFSLALERHAFAFADMLLVEGLKELPLPKLLMIDAERRIVKLWQQGSISNVLGFISPDDPQHYTDYGLPVMQRDNVEAIA
HFVESILLERAKAHYPLNGLLLAGGQSSRMGSDKALLSYHGDNQLQHTAALLREVCCNVYVSCRQEQAEHYCQFGIPLIT
DAYLGIGPMGGLLSAQQAHPNAAWLVTACDMPLLTPKTLQQLAEERQPLRFATAFRHPQTQRLEPLFAIYEPKTRIPLLL
QHAEGNNSLASFLATARIAALMPDAAQSLLNINTPDEQKSFEQNQGRA
>Mature_367_residues
TFHPFEIAFCGYSGSGKTTLLTKVVRSLAERYSVACYKHGCHHFSLDKEGKDSWLMRQAGASAVMIGDPQQQALMAERGV
FSLALERHAFAFADMLLVEGLKELPLPKLLMIDAERRIVKLWQQGSISNVLGFISPDDPQHYTDYGLPVMQRDNVEAIAH
FVESILLERAKAHYPLNGLLLAGGQSSRMGSDKALLSYHGDNQLQHTAALLREVCCNVYVSCRQEQAEHYCQFGIPLITD
AYLGIGPMGGLLSAQQAHPNAAWLVTACDMPLLTPKTLQQLAEERQPLRFATAFRHPQTQRLEPLFAIYEPKTRIPLLLQ
HAEGNNSLASFLATARIAALMPDAAQSLLNINTPDEQKSFEQNQGRA

Specific function: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) [H]

COG id: COG0746

COG function: function code H; Molybdopterin-guanine dinucleotide biosynthesis protein A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the mobA family [H]

Homologues:

Organism=Escherichia coli, GI1790288, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693204, Length=165, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR002820
- InterPro:   IPR013482 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 40813; Mature: 40682

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFHPFEIAFCGYSGSGKTTLLTKVVRSLAERYSVACYKHGCHHFSLDKEGKDSWLMRQA
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GASAVMIGDPQQQALMAERGVFSLALERHAFAFADMLLVEGLKELPLPKLLMIDAERRIV
CCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
KLWQQGSISNVLGFISPDDPQHYTDYGLPVMQRDNVEAIAHFVESILLERAKAHYPLNGL
HHHHCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
LLAGGQSSRMGSDKALLSYHGDNQLQHTAALLREVCCNVYVSCRQEQAEHYCQFGIPLIT
EEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DAYLGIGPMGGLLSAQQAHPNAAWLVTACDMPLLTPKTLQQLAEERQPLRFATAFRHPQT
HHHHCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCC
QRLEPLFAIYEPKTRIPLLLQHAEGNNSLASFLATARIAALMPDAAQSLLNINTPDEQKS
HHCCCHHEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHH
FEQNQGRA
HHHHCCCC
>Mature Secondary Structure 
TFHPFEIAFCGYSGSGKTTLLTKVVRSLAERYSVACYKHGCHHFSLDKEGKDSWLMRQA
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GASAVMIGDPQQQALMAERGVFSLALERHAFAFADMLLVEGLKELPLPKLLMIDAERRIV
CCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
KLWQQGSISNVLGFISPDDPQHYTDYGLPVMQRDNVEAIAHFVESILLERAKAHYPLNGL
HHHHCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
LLAGGQSSRMGSDKALLSYHGDNQLQHTAALLREVCCNVYVSCRQEQAEHYCQFGIPLIT
EEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DAYLGIGPMGGLLSAQQAHPNAAWLVTACDMPLLTPKTLQQLAEERQPLRFATAFRHPQT
HHHHCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCC
QRLEPLFAIYEPKTRIPLLLQHAEGNNSLASFLATARIAALMPDAAQSLLNINTPDEQKS
HHCCCHHEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHH
FEQNQGRA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: molybdopterin; GTP [C]

Specific reaction: molybdopterin + GTP = molybdopterin guanine dinucleotide + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]